Gene Details:

• Gene ID: AT3G15660
• Gene Symbol: ATGRX4, GRX4, GRXS15
• Gene Name: A. THALIANA GLUTAREDOXIN 4, glutaredoxin 4, glutaredoxin S15
• Description: glutaredoxin 4;(source:Araport11)
• TAIR Accession: locus:2093297
• Genome: Araport11_genome_release
• Species: Arabidopsis thaliana

Transcripts:

• AT3G15660.1     AT3G15660.2

Plant Ontology Annotations:

• PO:0000084  — plant sperm cell — célula espermática o esperma (Spanish, exact), male gamete (exact), microgamete (exact), 植物精子細胞 (Japanese, exact), sperm nucleus (related), sperm cell (broad)

Gene Ontology:

• GO:0005829  — located in — cytosol
• GO:0046872  — enables — metal ion binding
• GO:0005759  — is active in — mitochondrial matrix
• GO:0009249  — acts upstream of or within — protein lipoylation
• GO:0005515  — enables — protein binding
• GO:0051537  — enables — 2 iron, 2 sulfur cluster binding
• GO:0005739  — located in — mitochondrion
• GO:0015036  — enables — disulfide oxidoreductase activity

Germplasm Phenotype:

• grxs15-2  — Segregates for embryo lethality at around 23%.Early arrest at globular stage.
• grxs15-3  — Segregates around 20% for embryo lethal phenotype. Early globular arrest.

Function-related keywords:

• plant sperm cell

Literature:

• Proteomic identification of divalent metal cation binding proteins in plant mitochondria.   DOI:  10.1016/s0014-5793(03)00101-7 ;  PMID:  12606038
• Molecular definition of the ascorbate-glutathione cycle in Arabidopsis mitochondria reveals dual targeting of antioxidant defenses in plants.   DOI:  10.1074/jbc.M307525200 ;  PMID:  12954611
• AtGRXcp, an Arabidopsis chloroplastic glutaredoxin, is critical for protection against protein oxidative damage.   DOI:  10.1074/jbc.M601354200 ;  PMID:  16829529
• Confocal imaging of glutathione redox potential in living plant cells.   DOI:  10.1111/j.1365-2818.2008.02030.x ;  PMID:  18778428
• Genome-wide identification of EMBRYO-DEFECTIVE (EMB) genes required for growth and development in Arabidopsis.   DOI:  10.1111/nph.16071 ;  PMID:  31334862
• Alteration of iron responsive gene expression in Arabidopsis glutaredoxin S17 loss of function plants with or without iron stress.   DOI:  10.1080/15592324.2020.1758455 ;  PMID:  32351167
• The Arabidopsis Mitochondrial Glutaredoxin GRXS15 Provides [2Fe-2S] Clusters for ISCA-Mediated [4Fe-4S] Cluster Maturation.   DOI:  10.3390/ijms21239237 ;  PMID:  33287436
• The function of glutaredoxin GRXS15 is required for lipoyl-dependent dehydrogenases in mitochondria.   DOI:  10.1093/plphys/kiab172 ;  PMID:  33856472
• Proteomic identification of divalent metal cation binding proteins in plant mitochondria.   DOI:  10.1016/s0014-5793(03)00101-7 ;  PMID:  12606038
• Molecular definition of the ascorbate-glutathione cycle in Arabidopsis mitochondria reveals dual targeting of antioxidant defenses in plants.   DOI:  10.1074/jbc.M307525200 ;  PMID:  12954611
• Proteomic identification of divalent metal cation binding proteins in plant mitochondria.   DOI:  10.1016/s0014-5793(03)00101-7 ;  PMID:  12606038
• AtGRXcp, an Arabidopsis chloroplastic glutaredoxin, is critical for protection against protein oxidative damage.   DOI:  10.1074/jbc.M601354200 ;  PMID:  16829529
• Analysis of protein complexes in Arabidopsis leaves using size exclusion chromatography and label-free protein correlation profiling.   DOI:  10.1016/j.jprot.2017.06.004 ;  PMID:  28627464

Sequences: