Gene Details:

• Gene ID: AT3G15020
• Gene Symbol: mMDH2
• Gene Name: mitochondrial malate dehydrogenase 2
• Description: Lactate/malate dehydrogenase family protein;(source:Araport11)
• TAIR Accession:
• Genome: Araport11_genome_release
• Species: Arabidopsis thaliana

Transcripts:

• AT3G15020.1     AT3G15020.2

Plant Ontology Annotations:

• PO:0025195  — pollen tube cell — célula del tubo polínico (Spanish, exact), 花粉管細胞 (Japanese, exact)
• PO:0025281  — pollen — polen (Spanish, exact), pollen grain (exact), 花粉 (Japanese, exact)

Germplasm Phenotype:

• mmdh1-2 mmdh2-1  — mmdh1-2 mmdh2-1 double mutants have no detectable mitochondrial malate dehydrogenase (MDH) activity and over a 40% reduction in total leaf MDH activity. They also have growth defects under long and short days.

Function-related keywords:

• pollen tube cell ,  pollen

Literature:

• Genomic and proteomic analysis of mitochondrial carrier proteins in Arabidopsis.   DOI:  10.1104/pp.009985 ;  PMID:  12586869
• The age of the Arabidopsis thaliana genome duplication.   DOI:  10.1023/a:1023001130337 ;  PMID:  12777046
• Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.   DOI:  10.1105/tpc.016055 ;  PMID:  14671022
• Linking protein fractionation with multidimensional monolithic reversed-phase peptide chromatography/mass spectrometry enhances protein identification from complex mixtures even in the presence of abundant proteins.   DOI:  10.1002/rcm.1376 ;  PMID:  15052571
• Untangling multi-gene families in plants by integrating proteomics into functional genomics.   DOI:  10.1016/j.phytochem.2004.04.021 ;  PMID:  15276449
• Coordination of nuclear and mitochondrial genome expression during mitochondrial biogenesis in Arabidopsis.   DOI:  10.1105/tpc.104.030254 ;  PMID:  15829605
• Computational identification of 69 retroposons in Arabidopsis.   DOI:  10.1104/pp.105.060244 ;  PMID:  15923328
• Identification of Arabidopsis salt and osmotic stress responsive proteins using two-dimensional difference gel electrophoresis and mass spectrometry.   DOI:  10.1002/pmic.200401282 ;  PMID:  16254930
• Modifications to the Arabidopsis defense proteome occur prior to significant transcriptional change in response to inoculation with Pseudomonas syringae.   DOI:  10.1104/pp.106.086231 ;  PMID:  17028151
• Alternative and effective proteomic analysis in Arabidopsis.   DOI:  10.1002/pmic.200700346 ;  PMID:  17828791
• The rules of gene expression in plants: organ identity and gene body methylation are key factors for regulation of gene expression in Arabidopsis thaliana.   DOI:  10.1186/1471-2164-9-438 ;  PMID:  18811951
• Transcriptional profiling of mature Arabidopsis trichomes reveals that NOECK encodes the MIXTA-like transcriptional regulator MYB106.   DOI:  10.1104/pp.108.126979 ;  PMID:  18805951
• Transcriptome analyses show changes in gene expression to accompany pollen germination and tube growth in Arabidopsis.   DOI:  10.1104/pp.108.126375 ;  PMID:  18775970
• Divalent metal ions in plant mitochondria and their role in interactions with proteins and oxidative stress-induced damage to respiratory function.   DOI:  10.1104/pp.109.147942 ;  PMID:  20018591
• Mitochondrial malate dehydrogenase lowers leaf respiration and alters photorespiration and plant growth in Arabidopsis.   DOI:  10.1104/pp.110.161612 ;  PMID:  20876337
• Proteomic analyses of apoplastic proteins from germinating Arabidopsis thaliana pollen.   DOI:  10.1016/j.bbapap.2011.07.013 ;  PMID:  21798377
• The trehalose 6-phosphate/SnRK1 signaling pathway primes growth recovery following relief of sink limitation.   DOI:  10.1104/pp.113.220657 ;  PMID:  23735508
• Selected reaction monitoring to determine protein abundance in Arabidopsis using the Arabidopsis proteotypic predictor.   DOI:  10.1104/pp.113.225524 ;  PMID:  24296071
• Plants Possess a Cyclic Mitochondrial Metabolic Pathway similar to the Mammalian Metabolic Repair Mechanism Involving Malate Dehydrogenase and l-2-Hydroxyglutarate Dehydrogenase.   DOI:  10.1093/pcp/pcv108 ;  PMID:  26203119
• 2-Hydroxy Acids in Plant Metabolism.   DOI:  10.1199/tab.0182 ;  PMID:  26380567
• Loss of Mitochondrial Malate Dehydrogenase Activity Alters Seed Metabolism Impairing Seed Maturation and Post-Germination Growth in Arabidopsis.   DOI:  10.1104/pp.16.01654 ;  PMID:  27208265
• Negative regulation of cadmium tolerance in Arabidopsis by MMDH2.   DOI:  10.1007/s11103-019-00923-w ;  PMID:  31617145
• Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins.   DOI:  10.1105/tpc.016055 ;  PMID:  14671022
• Modifications to the Arabidopsis defense proteome occur prior to significant transcriptional change in response to inoculation with Pseudomonas syringae.   DOI:  10.1104/pp.106.086231 ;  PMID:  17028151
• Membrane proteomic analysis of Arabidopsis thaliana using alternative solubilization techniques.   DOI:  10.1021/pr060525b ;  PMID:  17432890
• Hydroponic isotope labelling of entire plants (HILEP) for quantitative plant proteomics; an oxidative stress case study.   DOI:  10.1016/j.phytochem.2008.04.007 ;  PMID:  18538804
• Analysis of the Arabidopsis cytosolic proteome highlights subcellular partitioning of central plant metabolism.   DOI:  10.1021/pr1009433 ;  PMID:  21166475
• Modifications to the Arabidopsis defense proteome occur prior to significant transcriptional change in response to inoculation with Pseudomonas syringae.   DOI:  10.1104/pp.106.086231 ;  PMID:  17028151
• Membrane proteomic analysis of Arabidopsis thaliana using alternative solubilization techniques.   DOI:  10.1021/pr060525b ;  PMID:  17432890
• Hydroponic isotope labelling of entire plants (HILEP) for quantitative plant proteomics; an oxidative stress case study.   DOI:  10.1016/j.phytochem.2008.04.007 ;  PMID:  18538804
• Analysis of the Arabidopsis cytosolic proteome highlights subcellular partitioning of central plant metabolism.   DOI:  10.1021/pr1009433 ;  PMID:  21166475

Sequences: