Gene Details:

• Gene ID: AT3G12400
• Gene Symbol: ATELC, ELC, Vps23A
• Gene Name: Vacuolar protein sorting 23A
• Description: Ubiquitin-conjugating enzyme/RWD-like protein;(source:Araport11)
• TAIR Accession:
• Genome: Araport11_genome_release
• Species: Arabidopsis thaliana

Transcripts:

• AT3G12400.1     AT3G12400.3     AT3G12400.2

Plant Ontology Annotations:

• PO:0000037  — shoot axis apex — ápice del epiblasto (epiblastema) (Spanish, exact), シュート頂、茎頂 (Japanese, exact)
• PO:0008019  — leaf lamina base — base de la lámina de la hoja (Spanish, exact), 葉身基部 (Japanese, exact)
• PO:0009005  — root — raíz (Spanish, exact), radices (exact, plural), radix (exact), 根 (Japanese, exact), aerial root (narrow), climbing root (narrow)
• PO:0009006  — shoot system — sistema de epiblasto (epiblastema) (Spanish, exact), シュート系、苗条系 (Japanese, exact), Poaceae crown (related), shoot (related), thalli (related), thallus (related), tree crown (narrow)
• PO:0009009  — plant embryo — embrión (Spanish, exact), 植物胚 (Japanese, exact), germ (related), embryo (broad)
• PO:0009025  — vascular leaf — foliage leaf (exact), hoja vascular (Spanish, exact), leaf, vascular (exact), vascular leaves (exact, plural), 維管束のある葉, または維管束植物の葉 (Japanese, exact), crozier (related), macrophyll (related), megaphyll (related), ascidia (narrow), ascidium (narrow), fiddlehead (narrow), frond (narrow), needle-like leaf (narrow), pitcher (narrow), pitcher blade (narrow), pitcher-blade (narrow), scale-like leaf (narrow), sterile frond (narrow), trophophyll (narrow)
• PO:0009029  — stamen — estambre (Spanish, exact), 雄蕊 (Japanese, exact), Poaceae stamen (narrow), Zea stamen (narrow)
• PO:0009031  — sepal — sépalo (Spanish, exact), がく片 (Japanese, exact)
• PO:0009046  — flower — flor (Spanish, exact), 花 (Japanese, exact), floret (related), Asteraceae floret (narrow), basal flower (narrow), double flower (narrow), hermaphrodite flower (narrow), monoclinous flower (narrow), perfect flower (narrow)
• PO:0009052  — inflorescence flower pedicel — 小花柄 (Japanese, related), pedicelo (Spanish, broad)
• PO:0020030  — cotyledon — cotiledón (Spanish, exact), seed leaf (exact), 子葉 (Japanese, exact)
• PO:0020038  — petiole — pecíolo (Spanish, exact), 葉柄 (Japanese, exact)
• PO:0020100  — hypocotyl — hipocótile (Spanish, exact), 胚軸 (Japanese, exact)
• PO:0020137  — leaf apex — ápice de la hoja (Spanish, exact), 葉先 (Japanese, exact), leaf lamina apex (narrow), phyllid apex (narrow)
• PO:0025022  — collective leaf structure — estructura colectiva de hoja (Spanish, exact), leaf series (exact), 葉が集まった構造 (Japanese, exact), leaf whorl (narrow), rosette (narrow), cycle (broad), verticil (broad)
• PO:0025281  — pollen — polen (Spanish, exact), pollen grain (exact), 花粉 (Japanese, exact)

Germplasm Phenotype:

• elc  — About 2% of all trichomes had more than one nucleus. Among the cluster-like trichomes, 93% had several nuclei, whereas 0.4% of the trichomes with a normal appearance had more than one nucleus.
• elc  — In the mutant, about 2% of the trichomes showed a cluster phenotype. In clusters, two stems were usually formed that appeared to separate just above the epidermal surface giving the trichome a moose-horn-like appearance.
• elc  — The mutant has slightly less branching of trichomes than in wild type.
• elc kis-T1  — Epidermal pavement cells are strongly reduced in size.
• elc kis-T1  — Increase in the frequency of trichomes with more stems.
• elc kis-T1  — Leaf architecture is grossly disturbed.
• elc kis-T1  — Many cells contain multiple nuclei and nuclear anomalies.
• elc kis-T1  — Synergistic phenotype compared to both single mutants.
• elc sti  — The mutant showed cluster-like trichomes lacking additional branches.
• kak elc  — The double mutant exhibits an additive trichome phenotype. The cluster frequency and number of nuclei was similar to that in elc single mutants and the number of branches was similar to that in kak single mutants.

Function-related keywords:

• shoot axis apex ,  leaf lamina base ,  root ,  shoot system ,  plant embryo ,  vascular leaf ,  stamen ,  sepal ,  flower ,  inflorescence flower pedicel ,  cotyledon ,  petiole ,  hypocotyl ,  leaf apex ,  collective leaf structure ,  pollen

Literature:

• Ubiquitylation in plants: a post-genomic look at a post-translational modification.   DOI:  10.1016/s1360-1385(01)02080-5 ;  PMID:  11590065
• Inactivation of the chloroplast ATP synthase gamma subunit results in high non-photochemical fluorescence quenching and altered nuclear gene expression in Arabidopsis thaliana.   DOI:  10.1074/jbc.M308435200 ;  PMID:  14576160
• The Arabidopsis elch mutant reveals functions of an ESCRT component in cytokinesis.   DOI:  10.1242/dev.02654 ;  PMID:  17090720
• Integration of Arabidopsis thaliana stress-related transcript profiles, promoter structures, and cell-specific expression.   DOI:  10.1186/gb-2007-8-4-r49 ;  PMID:  17408486
• Global analysis of Arabidopsis gene expression uncovers a complex array of changes impacting pathogen response and cell cycle during geminivirus infection.   DOI:  10.1104/pp.108.121038 ;  PMID:  18650403
• Transcriptome analyses show changes in gene expression to accompany pollen germination and tube growth in Arabidopsis.   DOI:  10.1104/pp.108.126375 ;  PMID:  18775970
• A unique plant ESCRT component, FREE1, regulates multivesicular body protein sorting and plant growth.   DOI:  10.1016/j.cub.2014.09.014 ;  PMID:  25438943
• Arabidopsis ALIX Regulates Stomatal Aperture and Turnover of Abscisic Acid Receptors.   DOI:  10.1105/tpc.19.00399 ;  PMID:  31363038
• ESCRT-I Component VPS23A Sustains Salt Tolerance by Strengthening the SOS Module in Arabidopsis.   DOI:  10.1016/j.molp.2020.05.010 ;  PMID:  32439321
• SINAT E3 Ubiquitin Ligases Mediate FREE1 and VPS23A Degradation to Modulate Abscisic Acid Signaling.   DOI:  10.1105/tpc.20.00267 ;  PMID:  32753431
• The deubiquitinases UBP12 and UBP13 integrate with the E3 ubiquitin ligase XBAT35.2 to modulate VPS23A stability in ABA signaling.   DOI:  10.1126/sciadv.abl5765 ;  PMID:  35385312
• Plant autophagosomes mature into amphisomes prior to their delivery to the central vacuole.   DOI:  10.1083/jcb.202203139 ;  PMID:  36260289
• Exploring the ESCRTing machinery in eukaryotes.   DOI:  10.1016/j.tplants.2006.01.008 ;  PMID:  16488176

Sequences: