AT3G12400

Gene Details

Gene ID: AT3G12400
Gene Symbol: ATELC, ELC, Vps23A
Gene Name: Vacuolar protein sorting 23A
Description: Ubiquitin-conjugating enzyme/RWD-like protein;(source:Araport11)
TAIR Accession:
Genome: Araport11_genome_release
Species: Arabidopsis thaliana

Functional Descriptions

PO:0000037 — shoot axis apex — ápice del epiblasto (epiblastema) (Spanish, exact), シュート頂、茎頂 (Japanese, exact)
PO:0008019 — leaf lamina base — base de la lámina de la hoja (Spanish, exact), 葉身基部 (Japanese, exact)
PO:0009005 — root — raíz (Spanish, exact), radices (exact, plural), radix (exact), 根 (Japanese, exact), aerial root (narrow), climbing root (narrow)
PO:0009006 — shoot system — sistema de epiblasto (epiblastema) (Spanish, exact), シュート系、苗条系 (Japanese, exact), Poaceae crown (related), shoot (related), thalli (related), thallus (related), tree crown (narrow)
PO:0009009 — plant embryo — embrión (Spanish, exact), 植物胚 (Japanese, exact), germ (related), embryo (broad)
PO:0009025 — vascular leaf — foliage leaf (exact), hoja vascular (Spanish, exact), leaf, vascular (exact), vascular leaves (exact, plural), 維管束のある葉, または維管束植物の葉 (Japanese, exact), crozier (related), macrophyll (related), megaphyll (related), ascidia (narrow), ascidium (narrow), fiddlehead (narrow), frond (narrow), needle-like leaf (narrow), pitcher (narrow), pitcher blade (narrow), pitcher-blade (narrow), scale-like leaf (narrow), sterile frond (narrow), trophophyll (narrow)
PO:0009029 — stamen — estambre (Spanish, exact), 雄蕊 (Japanese, exact), Poaceae stamen (narrow), Zea stamen (narrow)
PO:0009031 — sepal — sépalo (Spanish, exact), がく片 (Japanese, exact)
PO:0009046 — flower — flor (Spanish, exact), 花 (Japanese, exact), floret (related), Asteraceae floret (narrow), basal flower (narrow), double flower (narrow), hermaphrodite flower (narrow), monoclinous flower (narrow), perfect flower (narrow)
PO:0009052 — inflorescence flower pedicel — 小花柄 (Japanese, related), pedicelo (Spanish, broad)
PO:0020030 — cotyledon — cotiledón (Spanish, exact), seed leaf (exact), 子葉 (Japanese, exact)
PO:0020038 — petiole — pecíolo (Spanish, exact), 葉柄 (Japanese, exact)
PO:0020100 — hypocotyl — hipocótile (Spanish, exact), 胚軸 (Japanese, exact)
PO:0020137 — leaf apex — ápice de la hoja (Spanish, exact), 葉先 (Japanese, exact), leaf lamina apex (narrow), phyllid apex (narrow)
PO:0025022 — collective leaf structure — estructura colectiva de hoja (Spanish, exact), leaf series (exact), 葉が集まった構造 (Japanese, exact), leaf whorl (narrow), rosette (narrow), cycle (broad), verticil (broad)
PO:0025281 — pollen — polen (Spanish, exact), pollen grain (exact), 花粉 (Japanese, exact)

elc — About 2% of all trichomes had more than one nucleus. Among the cluster-like trichomes, 93% had several nuclei, whereas 0.4% of the trichomes with a normal appearance had more than one nucleus.
elc — In the mutant, about 2% of the trichomes showed a cluster phenotype. In clusters, two stems were usually formed that appeared to separate just above the epidermal surface giving the trichome a moose-horn-like appearance.
elc — The mutant has slightly less branching of trichomes than in wild type.
elc kis-T1 — Epidermal pavement cells are strongly reduced in size.
elc kis-T1 — Increase in the frequency of trichomes with more stems.
elc kis-T1 — Leaf architecture is grossly disturbed.
elc kis-T1 — Many cells contain multiple nuclei and nuclear anomalies.
elc kis-T1 — Synergistic phenotype compared to both single mutants.
elc sti — The mutant showed cluster-like trichomes lacking additional branches.
kak elc — The double mutant exhibits an additive trichome phenotype. The cluster frequency and number of nuclei was similar to that in elc single mutants and the number of branches was similar to that in kak single mutants.

Functional Keywords

Literature and News

Gene Resources

Sequences

cDNA Sequence

>AT3G12400.1
AATCTCCTCCCCAGTTGTCGTCGTCATCTTCAATTTGGACTTCCAACGCCGACACCGTTTAACTCCGATGGTTCCCCCGCCGTCTAATCCGCAGCAGGTTCAGCAGTTCCTCTCCTCTGCCCTCTCCCAGCGCGGCCCATCTTCAGTCCCCTACGAAGAGTCCAACAAGTGGTTGATCCGGCAACATCTACTTAACCTAATCTCTTCTTACCCTTCCTTAGAGCCCAAAACGGCATCGTTTATGCACAACGATGGTCGCTCCGTCAACCTCCTTCAAGCAGATGGTACGATTCCGATGCCTTTTCATGGAGTCACCTATAACATACCTGTGATTATCTGGCTCCTCGAGTCATATCCTCGTCATCCTCCTTGCGTCTATGTGAATCCCACCGCTGATATGATCATCAAGCGACCTCACGCACATGTCACTCCTTCTGGTCTCGTTTCTCTTCCGTACCTTCAGAATTGGGTCTACCCTAGCTCCAATCTCGTAGATCTCGTCTCCGATCTCAGCGCTGCTTTTGCTCGTGATCCGCCTCTTTATTCTCGACGCCGTCCTCAGCCACCGCCACCGTCTCCTCCTACGGTATACGATTCGTCTCTGTCACGACCTCCTTCGGCTGATCAGTCATTGCCTAGACCGTTCCCGCCATCACCTTACGGCGGAGGAGTAAGTAGGGTGCAAGTGCAGCATGTTCACCACCAGCAGCAATCTGATGATGCGGCGGAGGTTTTCAAGAGAAATGCGATTAATAAGATGGTGGAGATGGTTCATAGCGATTTGGTTTCGATGAGGAGAGCCAGAGAAGCTGAAGCAGAGGAGCTGCTGAGCTTGCAAGCTGGGCTGAAGAGAAGAGAGGATGAGCTTAATATAGGGTTGAAAGAGATGGTTGAGGAGAAAGAAACACTTGAACAACAATTACAGATTATCTCCATGAACACTGATATTCTAGACTCGTGGGTTAGAGAGAACCAAGGCAAAACCAAGAATTTAGTTGATTTGGATGTGGATAATGCTTTTGAATGTGGTGACACACTCTCTAAGCAGATGTTAGAGTGTACTGCTTTGGATTTAGCCATTGAAGATGCTATTTATTCCTTGGATAAGTCGTTTCAAGATGGTGTTGTTCCCTTTGATCAGTATTTGAGGAATGTGAGGTTGTTGTCGAGAGAACAGTTCTTCCACCGAGCCACGGGTTCTAAAGTCAGGGCGGCACAAATGGAGGTTCAGGTTGCAGCCATCGCAGGTAGGTTACATTCATGAATGAAATTCAGTGTTTTTGTTTGCGGGATACTGTGTCACACAATGCTGGTTTATATAGTCTGAGATTAGCATCTTTGAGGAGTATTTCTGTGGCTATGCGTGTGATGATGGTTCCTCTTTAAGATTGAATTAAATGTCTATAGACTATATATACACGTACACTGTTGTGCACATACATATTTGAATGGATCAGGGCCTGAGAATCGTCTCCTTTTGTGATCTATGACTACTTTTTTACATGTTGGGGATCTTTGTGATAAACAGTATTATTATCTAATGAATCAATCAATTGGTTTGAGAATGTTAGTATCTTTGTTTTGGATATTGGAAC
>AT3G12400.3
AATCTCCTCCCCAGTTGTCGTCGTCATCTTCAATTTGGACTTCCAACGCCGACACCGTTTAACTCCGATGGTTCCCCCGCCGTCTAATCCGCAGCAGGTTCAGCAGTTCCTCTCCTCTGCCCTCTCCCAGCGCGGCCCATCTTCAGTCCCCTACGAAGAGTCCAACAAGTGGTTGATCCGGCAACATCTACTTAACCTAATCTCTTCTTACCCTTCCTTAGAGCCCAAAACGGCATCGTTTATGCACAACGATGGTCGCTCCGTCAACCTCCTTCAAGCAGATGGTACGATTCCGATGCCTTTTCATGGAGTCACCTATAACATACCTGTGATTATCTGGCTCCTCGAGTCATATCCTCGTCATCCTCCTTGCGTCTATGTGAATCCCACCGCTGATATGATCATCAAGCGACCTCACGCACATGTCACTCCTTCTGGTCTCGTTTCTCTTCCGTACCTTCAGAATTGGGTCTACCCTAGCTCCAATCTCGTAGATCTCGTCTCCGATCTCAGCGCTGCTTTTGCTCGTGATCCGCCTCTTTATTCTCGACGCCGTCCTCAGCCACCGCCACCGTCTCCTCCTACGGTATACGATTCGTCTCTGTCACGACCTCCTTCGGCTGATCAGTCATTGCCTAGACCGTTCCCGCCATCACCTTACGGCGGAGGAGTAAGTAGGGTGCAAGTGCAGCATGTTCACCACCAGCAGCAATCTGATGATGCGGCGGAGGTTTTCAAGAGAAATGCGATTAATAAGATGGTGGAGATGGTTCATAGCGATTTGGTTTCGATGAGGAGAGCCAGAGAAGCTGAAGCAGAGGAGCTGCTGAGCTTGCAAGCTGGGCTGAAGAGAAGAGAGGATGAGCTTAATATAGGGTTGAAAGAGATGGTTGAGGAGAAAGAAACACTTGAACAACAATTACAGATTATCTCCATGAACACTGATATTCTAGACTCGTGGGTTAGAGAGAACCAAGGCAAAACCAAGAATTTAGTTGATTTGGATGTGGATAATGCTTTTGAATGTGGTGACACACTCTCTAAGCAGATGTTAGAGTGTACTGCTTTGGATTTAGCCATTGAAGATGCTATTTATTCCTTGGATAAGTCGTTTCAAGATGGTGTTGTTCCCTTTGATCAGTATTTGAGGAATGTGAGGTTGTTGTCGAGAGAACAGTTCTTCCACCGAGCCACGGGTTCTAAAGTCAGGGCGGCACAAATGGAGGTTCAGGTTGCAGCCATCGCAGGTAGGTTACATTCATGAATGAAATTCAGTGTTTTTGTTTGCGGGATACTGTGTCACACAATGCTGGTTTATATAGTCTGAGATTAGCATCTTTGAGGAGTATTTCTGTGGCTATGCGTGTGATGATGGTTCCTCTTTAAGATTGAATTAAATGTCTATAGACTATATATACACGTACACTGTTGTGCACATACATATTTGAATGGATCAGGGCCTGAGAATCGTCTCCTTTTGTGATCTATGACTACTTTTTTACATGTTGGGGATCTTTGTGATAAACAGTATTATTATCTAATGAATCAATCAATTGGTTTGAGAATGTTAGTATCTTTGTTTTGGATATTGGAAC
>AT3G12400.2
AATCTCCTCCCCAGTTGTCGTCGTCATCTTCAATTTGGACTTCCAACGCCGACACCGTTTAACTCCGATGGTTCCCCCGCCGTCTAATCCGCAGCAGGTTCAGCAGTTCCTCTCCTCTGCCCTCTCCCAGCGCGGCCCATCTTCAGTCCCCTACGAAGAGTCCAACAAGTGGTTGATCCGGCAACATCTACTTAACCTAATCTCTTCTTACCCTTCCTTAGAGCCCAAAACGGCATCGTTTATGCACAACGATGGTCGCTCCGTCAACCTCCTTCAAGCAGATGGTACGATTCCGATGCCTTTTCATGGAGTCACCTATAACATACCTGTGATTATCTGGCTCCTCGAGTCATATCCTCGTCATCCTCCTTGCGTCTATGTGAATCCCACCGCTGATATGATCATCAAGCGACCTCACGCACATGTCACTCCTTCTGGTCTCGTTTCTCTTCCGTACCTTCAGAATTGGGTCTACCCTAGCTCCAATCTCGTAGATCTCGTCTCCGATCTCAGCGCTGCTTTTGCTCGTGATCCGCCTCTTTATTCTCGACGCCGTCCTCAGCCACCGCCACCGTCTCCTCCTACGGTATACGATTCGTCTCTGTCACGACCTCCTTCGGCTGATCAGTCATTGCCTAGACCGTTCCCGCCATCACCTTACGGCGGAGGAGTAAGTAGGGTGCAAGTGCAGCATGTTCACCACCAGCAGCAATCTGATGATGCGGCGGAGGTTTTCAAGAGAAATGCGATTAATAAGATGGTGGAGATGGTTCATAGCGATTTGGTTTCGATGAGGAGAGCCAGAGAAGCTGAAGCAGAGGAGCTGCTGAGCTTGCAAGCTGGGCTGAAGAGAAGAGAGGATGAGCTTAATATAGGGTTGAAAGAGATGGTTGAGGAGAAAGAAACACTTGAACAACAATTACAGATTATCTCCATGAACACTGATATTCTAGACTCGTGGGTTAGAGAGAACCAAGGCAAAACCAAGAATTTAGTTGATTTGGATGTGGATAATGCTTTTGAATGTGGTGACACACTCTCTAAGCAGATGTTAGAGTGTACTGCTTTGGATTTAGCCATTGAAGATGCTATTTATTCCTTGGATAAGTCGTTTCAAGATGGTGTTGTTCCCTTTGATCAGTATTTGAGGAATGTGAGGTTGTTGTCGAGAGAACAGTTCTTCCACCGAGCCACGGGTTCTAAAGTCAGGGCGGCACAAATGGAGGTTCAGGTTGCAGCCATCGCAGGTAGGTTACATTCATGAATGAAATTCAGTGTTTTTGTTTGCGGGATACTGTGTCACACAATGCTGGTTTATATAGTCTGAGATTAGCATCTTTGAGGAGTATTTCTGTGGCTATGCGTGTGATGATGGTTCCTCTTTAAGATTGAATTAAATGTCTATAGACTATATATACACGTACACTGTTGTGCACATACATATTTGAATGGATCAGGGCCTGAGAATCGTCTCCTTTTGTGATCTATGACTACTTTTTTACATGTTGGGGATCTTTGTGATAAACAGTATTATTATCTAATGAATCAATCAATTGGTTTGAGAATGTTAGTATCTTTGTTTTGGATATTGGAAC

CDS Sequence

>AT3G12400.1
ATGGTTCCCCCGCCGTCTAATCCGCAGCAGGTTCAGCAGTTCCTCTCCTCTGCCCTCTCCCAGCGCGGCCCATCTTCAGTCCCCTACGAAGAGTCCAACAAGTGGTTGATCCGGCAACATCTACTTAACCTAATCTCTTCTTACCCTTCCTTAGAGCCCAAAACGGCATCGTTTATGCACAACGATGGTCGCTCCGTCAACCTCCTTCAAGCAGATGGTACGATTCCGATGCCTTTTCATGGAGTCACCTATAACATACCTGTGATTATCTGGCTCCTCGAGTCATATCCTCGTCATCCTCCTTGCGTCTATGTGAATCCCACCGCTGATATGATCATCAAGCGACCTCACGCACATGTCACTCCTTCTGGTCTCGTTTCTCTTCCGTACCTTCAGAATTGGGTCTACCCTAGCTCCAATCTCGTAGATCTCGTCTCCGATCTCAGCGCTGCTTTTGCTCGTGATCCGCCTCTTTATTCTCGACGCCGTCCTCAGCCACCGCCACCGTCTCCTCCTACGGTATACGATTCGTCTCTGTCACGACCTCCTTCGGCTGATCAGTCATTGCCTAGACCGTTCCCGCCATCACCTTACGGCGGAGGAGTAAGTAGGGTGCAAGTGCAGCATGTTCACCACCAGCAGCAATCTGATGATGCGGCGGAGGTTTTCAAGAGAAATGCGATTAATAAGATGGTGGAGATGGTTCATAGCGATTTGGTTTCGATGAGGAGAGCCAGAGAAGCTGAAGCAGAGGAGCTGCTGAGCTTGCAAGCTGGGCTGAAGAGAAGAGAGGATGAGCTTAATATAGGGTTGAAAGAGATGGTTGAGGAGAAAGAAACACTTGAACAACAATTACAGATTATCTCCATGAACACTGATATTCTAGACTCGTGGGTTAGAGAGAACCAAGGCAAAACCAAGAATTTAGTTGATTTGGATGTGGATAATGCTTTTGAATGTGGTGACACACTCTCTAAGCAGATGTTAGAGTGTACTGCTTTGGATTTAGCCATTGAAGATGCTATTTATTCCTTGGATAAGTCGTTTCAAGATGGTGTTGTTCCCTTTGATCAGTATTTGAGGAATGTGAGGTTGTTGTCGAGAGAACAGTTCTTCCACCGAGCCACGGGTTCTAAAGTCAGGGCGGCACAAATGGAGGTTCAGGTTGCAGCCATCGCAGGTAGGTTACATTCATGA
>AT3G12400.3
ATGGTTCCCCCGCCGTCTAATCCGCAGCAGGTTCAGCAGTTCCTCTCCTCTGCCCTCTCCCAGCGCGGCCCATCTTCAGTCCCCTACGAAGAGTCCAACAAGTGGTTGATCCGGCAACATCTACTTAACCTAATCTCTTCTTACCCTTCCTTAGAGCCCAAAACGGCATCGTTTATGCACAACGATGGTCGCTCCGTCAACCTCCTTCAAGCAGATGGTACGATTCCGATGCCTTTTCATGGAGTCACCTATAACATACCTGTGATTATCTGGCTCCTCGAGTCATATCCTCGTCATCCTCCTTGCGTCTATGTGAATCCCACCGCTGATATGATCATCAAGCGACCTCACGCACATGTCACTCCTTCTGGTCTCGTTTCTCTTCCGTACCTTCAGAATTGGGTCTACCCTAGCTCCAATCTCGTAGATCTCGTCTCCGATCTCAGCGCTGCTTTTGCTCGTGATCCGCCTCTTTATTCTCGACGCCGTCCTCAGCCACCGCCACCGTCTCCTCCTACGGTATACGATTCGTCTCTGTCACGACCTCCTTCGGCTGATCAGTCATTGCCTAGACCGTTCCCGCCATCACCTTACGGCGGAGGAGTAAGTAGGGTGCAAGTGCAGCATGTTCACCACCAGCAGCAATCTGATGATGCGGCGGAGGTTTTCAAGAGAAATGCGATTAATAAGATGGTGGAGATGGTTCATAGCGATTTGGTTTCGATGAGGAGAGCCAGAGAAGCTGAAGCAGAGGAGCTGCTGAGCTTGCAAGCTGGGCTGAAGAGAAGAGAGGATGAGCTTAATATAGGGTTGAAAGAGATGGTTGAGGAGAAAGAAACACTTGAACAACAATTACAGATTATCTCCATGAACACTGATATTCTAGACTCGTGGGTTAGAGAGAACCAAGGCAAAACCAAGAATTTAGTTGATTTGGATGTGGATAATGCTTTTGAATGTGGTGACACACTCTCTAAGCAGATGTTAGAGTGTACTGCTTTGGATTTAGCCATTGAAGATGCTATTTATTCCTTGGATAAGTCGTTTCAAGATGGTGTTGTTCCCTTTGATCAGTATTTGAGGAATGTGAGGTTGTTGTCGAGAGAACAGTTCTTCCACCGAGCCACGGGTTCTAAAGTCAGGGCGGCACAAATGGAGGTTCAGGTTGCAGCCATCGCAGGTAGGTTACATTCATGA
>AT3G12400.2
ATGGTTCCCCCGCCGTCTAATCCGCAGCAGGTTCAGCAGTTCCTCTCCTCTGCCCTCTCCCAGCGCGGCCCATCTTCAGTCCCCTACGAAGAGTCCAACAAGTGGTTGATCCGGCAACATCTACTTAACCTAATCTCTTCTTACCCTTCCTTAGAGCCCAAAACGGCATCGTTTATGCACAACGATGGTCGCTCCGTCAACCTCCTTCAAGCAGATGGTACGATTCCGATGCCTTTTCATGGAGTCACCTATAACATACCTGTGATTATCTGGCTCCTCGAGTCATATCCTCGTCATCCTCCTTGCGTCTATGTGAATCCCACCGCTGATATGATCATCAAGCGACCTCACGCACATGTCACTCCTTCTGGTCTCGTTTCTCTTCCGTACCTTCAGAATTGGGTCTACCCTAGCTCCAATCTCGTAGATCTCGTCTCCGATCTCAGCGCTGCTTTTGCTCGTGATCCGCCTCTTTATTCTCGACGCCGTCCTCAGCCACCGCCACCGTCTCCTCCTACGGTATACGATTCGTCTCTGTCACGACCTCCTTCGGCTGATCAGTCATTGCCTAGACCGTTCCCGCCATCACCTTACGGCGGAGGAGTAAGTAGGGTGCAAGTGCAGCATGTTCACCACCAGCAGCAATCTGATGATGCGGCGGAGGTTTTCAAGAGAAATGCGATTAATAAGATGGTGGAGATGGTTCATAGCGATTTGGTTTCGATGAGGAGAGCCAGAGAAGCTGAAGCAGAGGAGCTGCTGAGCTTGCAAGCTGGGCTGAAGAGAAGAGAGGATGAGCTTAATATAGGGTTGAAAGAGATGGTTGAGGAGAAAGAAACACTTGAACAACAATTACAGATTATCTCCATGAACACTGATATTCTAGACTCGTGGGTTAGAGAGAACCAAGGCAAAACCAAGAATTTAGTTGATTTGGATGTGGATAATGCTTTTGAATGTGGTGACACACTCTCTAAGCAGATGTTAGAGTGTACTGCTTTGGATTTAGCCATTGAAGATGCTATTTATTCCTTGGATAAGTCGTTTCAAGATGGTGTTGTTCCCTTTGATCAGTATTTGAGGAATGTGAGGTTGTTGTCGAGAGAACAGTTCTTCCACCGAGCCACGGGTTCTAAAGTCAGGGCGGCACAAATGGAGGTTCAGGTTGCAGCCATCGCAGGTAGGTTACATTCATGA

Protein Sequence

>AT3G12400.1
MVPPPSNPQQVQQFLSSALSQRGPSSVPYEESNKWLIRQHLLNLISSYPSLEPKTASFMHNDGRSVNLLQADGTIPMPFHGVTYNIPVIIWLLESYPRHPPCVYVNPTADMIIKRPHAHVTPSGLVSLPYLQNWVYPSSNLVDLVSDLSAAFARDPPLYSRRRPQPPPPSPPTVYDSSLSRPPSADQSLPRPFPPSPYGGGVSRVQVQHVHHQQQSDDAAEVFKRNAINKMVEMVHSDLVSMRRAREAEAEELLSLQAGLKRREDELNIGLKEMVEEKETLEQQLQIISMNTDILDSWVRENQGKTKNLVDLDVDNAFECGDTLSKQMLECTALDLAIEDAIYSLDKSFQDGVVPFDQYLRNVRLLSREQFFHRATGSKVRAAQMEVQVAAIAGRLHS
>AT3G12400.3
MVPPPSNPQQVQQFLSSALSQRGPSSVPYEESNKWLIRQHLLNLISSYPSLEPKTASFMHNDGRSVNLLQADGTIPMPFHGVTYNIPVIIWLLESYPRHPPCVYVNPTADMIIKRPHAHVTPSGLVSLPYLQNWVYPSSNLVDLVSDLSAAFARDPPLYSRRRPQPPPPSPPTVYDSSLSRPPSADQSLPRPFPPSPYGGGVSRVQVQHVHHQQQSDDAAEVFKRNAINKMVEMVHSDLVSMRRAREAEAEELLSLQAGLKRREDELNIGLKEMVEEKETLEQQLQIISMNTDILDSWVRENQGKTKNLVDLDVDNAFECGDTLSKQMLECTALDLAIEDAIYSLDKSFQDGVVPFDQYLRNVRLLSREQFFHRATGSKVRAAQMEVQVAAIAGRLHS
>AT3G12400.2
MVPPPSNPQQVQQFLSSALSQRGPSSVPYEESNKWLIRQHLLNLISSYPSLEPKTASFMHNDGRSVNLLQADGTIPMPFHGVTYNIPVIIWLLESYPRHPPCVYVNPTADMIIKRPHAHVTPSGLVSLPYLQNWVYPSSNLVDLVSDLSAAFARDPPLYSRRRPQPPPPSPPTVYDSSLSRPPSADQSLPRPFPPSPYGGGVSRVQVQHVHHQQQSDDAAEVFKRNAINKMVEMVHSDLVSMRRAREAEAEELLSLQAGLKRREDELNIGLKEMVEEKETLEQQLQIISMNTDILDSWVRENQGKTKNLVDLDVDNAFECGDTLSKQMLECTALDLAIEDAIYSLDKSFQDGVVPFDQYLRNVRLLSREQFFHRATGSKVRAAQMEVQVAAIAGRLHS