Gene Details:

• Gene ID: AT3G11170
• Gene Symbol: AtFAD7, FAD7, FADD
• Gene Name: fatty acid desaturase 7, FATTY ACID DESATURASE D
• Description: fatty acid desaturase 7;(source:Araport11)
• TAIR Accession: locus:2074628
• Genome: Araport11_genome_release
• Species: Arabidopsis thaliana

Transcripts:

• AT3G11170.1

Gene Ontology:

• GO:0006636  — involved in — unsaturated fatty acid biosynthetic process
• GO:0009507  — located in — chloroplast
• GO:0006633  — acts upstream of or within — fatty acid biosynthetic process
• GO:0102839  — enables — 1-18:2-2-16:2-monogalactosyldiacylglycerol desaturase activity
• GO:0009409  — acts upstream of or within — response to cold
• GO:0102837  — enables — 1-18:2-2-16:1-monogalactosyldiacylglycerol desaturase activity
• GO:0042389  — enables — omega-3 fatty acid desaturase activity
• GO:0009941  — located in — chloroplast envelope
• GO:0102874  — enables — 1-16:0-2-18:2-digalactosyldiacylglycerol desaturase activity
• GO:0102875  — enables — 1-18:2-2-18:2-monogalactosyldiacylglycerol desaturase activity
• GO:0042170  — located in — plastid membrane
• GO:0102835  — enables — 1-18:2-2-16:0-monogalactosyldiacylglycerol desaturase activity
• GO:0102848  — enables — 1-18:2-2-18:2-digalactosyldiacylglycerol desaturase activity

Germplasm Phenotype:

• CS209  — altered fatty acid composition.
• CS3108  — altered fatty acid composition, glabrous, no other phenotypic effect.
• CS71655  — Altered fatty acid composition. Resistant to green peach aphids.
• CS8036  — reduction in desaturation of storage and membrane lipids; chilling sensitive; linoleic acid overproducer; linolenic acid underproducer.
• CS8042  — reduced glycerolipid n-3 desaturase (probably chloroplastic), chloroplast and extrachloroplast lipids are equally affected; decrease in 16:3 and 18:3 fatty acids, increase in 16:2 and 18:2 fatty acids; temperature sensitive, mutant effects most pronounced at growth temperatures greater that 26C; no visible phenotypic effects.

Literature:

• Wounding and chemicals induce expression of the Arabidopsis thaliana gene Thi2.1, encoding a fungal defense thionin, via the octadecanoid pathway.   DOI:  10.1016/s0014-5793(98)01251-4 ;  PMID:  9824308
• A role for jasmonate in pathogen defense of Arabidopsis.   DOI:  10.1073/pnas.95.12.7209 ;  PMID:  9618564
• The impact of alteration of polyunsaturated fatty acid levels on C6-aldehyde formation of Arabidopsis thaliana leaves.   DOI:  10.1104/pp.111.3.805 ;  PMID:  8754681
• Cloning of a temperature-regulated gene encoding a chloroplast omega-3 desaturase from Arabidopsis thaliana.   DOI:  10.1104/pp.106.4.1615 ;  PMID:  7846164
• A gene encoding a chloroplast omega-3 fatty acid desaturase complements alterations in fatty acid desaturation and chloroplast copy number of the fad7 mutant of Arabidopsis thaliana.   DOI:  S0021-9258(20)80498-0 ;  PMID:  8226956
• Plant defense in the absence of jasmonic acid: the role of cyclopentenones.   DOI:  10.1073/pnas.211311098 ;  PMID:  11592974
• Photoinhibition in mutants of Arabidopsis deficient in thylakoid unsaturation.   DOI:  10.1104/pp.004341 ;  PMID:  12068126
• Hormonal regulation of tissue-specific ectopic expression of an Arabidopsis endoplasmic reticulum-type omega-3 fatty acid desaturase (FAD3) gene.   DOI:  10.1007/s004250100575 ;  PMID:  11722119
• Plant growth-promoting rhizobacteria systemically protect Arabidopsis thaliana against Cucumber mosaic virus by a salicylic acid and NPR1-independent and jasmonic acid-dependent signaling pathway.   DOI:  10.1111/j.1365-313X.2004.02142.x ;  PMID:  15255867
• Temperature dependence of photosynthesis in Arabidopsis plants with modifications in Rubisco activase and membrane fluidity.   DOI:  10.1093/pcp/pci052 ;  PMID:  15695447
• Role of salicylic acid and fatty acid desaturation pathways in ssi2-mediated signaling.   DOI:  10.1104/pp.105.071662 ;  PMID:  16306139
• Enhanced cold tolerance in transgenic tobacco expressing a chloroplast omega-3 fatty acid desaturase gene under the control of a cold-inducible promoter.   DOI:  10.1007/s00425-005-0161-4 ;  PMID:  16292565
• Ozone-induced expression of the Arabidopsis FAD7 gene requires salicylic acid, but not NPR1 and SID2.   DOI:  10.1093/pcp/pci253 ;  PMID:  16415067
• Altered rates of protein transport in Arabidopsis mutants deficient in chloroplast membrane unsaturation.   DOI:  10.1016/j.phytochem.2006.04.008 ;  PMID:  16759675
• Genetic removal of tri-unsaturated fatty acids suppresses developmental and molecular phenotypes of an Arabidopsis tocopherol-deficient mutant. Whole-body mapping of malondialdehyde pools in a complex eukaryote.   DOI:  10.1074/jbc.M706838200 ;  PMID:  17928299
• Plastid omega3-fatty acid desaturase-dependent accumulation of a systemic acquired resistance inducing activity in petiole exudates of Arabidopsis thaliana is independent of jasmonic acid.   DOI:  10.1111/j.1365-313X.2007.03400.x ;  PMID:  18088304
• Tocopherols modulate extraplastidic polyunsaturated fatty acid metabolism in Arabidopsis at low temperature.   DOI:  10.1105/tpc.107.054718 ;  PMID:  18314499
• Global analysis of Arabidopsis gene expression uncovers a complex array of changes impacting pathogen response and cell cycle during geminivirus infection.   DOI:  10.1104/pp.108.121038 ;  PMID:  18650403
• Transcriptome analyses show changes in gene expression to accompany pollen germination and tube growth in Arabidopsis.   DOI:  10.1104/pp.108.126375 ;  PMID:  18775970
• Nonenzymatic oxidation of trienoic fatty acids contributes to reactive oxygen species management in Arabidopsis.   DOI:  10.1074/jbc.M807114200 ;  PMID:  18996838
• Light-regulated Arabidopsis ACBP4 and ACBP5 encode cytosolic acyl-CoA-binding proteins that bind phosphatidylcholine and oleoyl-CoA ester.   DOI:  10.1016/j.plaphy.2009.06.007 ;  PMID:  19589686
• The power of mutants for investigating jasmonate biosynthesis and signaling.   DOI:  10.1016/j.phytochem.2009.08.004 ;  PMID:  19740496
• Expression of ACBP4 and ACBP5 proteins is modulated by light in Arabidopsis.   DOI:  10.4161/psb.4.11.9718 ;  PMID:  20009557
• The octadecanoid signaling pathway participates in the chilling-induced transcription of ω-3 fatty acid desaturases in Arabidopsis.   DOI:  10.1016/j.plaphy.2010.11.013 ;  PMID:  21185196
• and long-term thermotolerance have different requirements for trienoic fatty acids.   DOI:  10.1093/jxb/err381 ;  PMID:  22140238
• Heterosis manifestation during early Arabidopsis seedling development is characterized by intermediate gene expression and enhanced metabolic activity in the hybrids.   DOI:  10.1111/j.1365-313X.2012.05021.x ;  PMID:  22487254
• Acyl-lipid metabolism.   DOI:  10.1199/tab.0161 ;  PMID:  23505340
• Plant lipidomics based on hydrophilic interaction chromatography coupled to ion trap time-of-flight mass spectrometry.   DOI:  10.1007/s11306-011-0318-z ;  PMID:  23463370
• FAD2 and FAD3 desaturases form heterodimers that facilitate metabolic channeling in vivo.   DOI:  10.1074/jbc.M114.572883 ;  PMID:  24811169
• Endogenous Arabidopsis messenger RNAs transported to distant tissues.   DOI:  10.1038/nplants.2015.25 ;  PMID:  27247031
• Membranes as Structural Antioxidants: RECYCLING OF MALONDIALDEHYDE TO ITS SOURCE IN OXIDATION-SENSITIVE CHLOROPLAST FATTY ACIDS.   DOI:  10.1074/jbc.M116.729921 ;  PMID:  27143359
• The pht4;1-3 mutant line contains a loss of function allele in the Fatty Acid Desaturase 7 gene caused by a remnant inactivated selection marker-a cautionary tale.   DOI:  10.7717/peerj.4134 ;  PMID:  29209580
• A Role for Tocopherol Biosynthesis in Arabidopsis Basal Immunity to Bacterial Infection.   DOI:  10.1104/pp.19.00618 ;  PMID:  31515446
• Plant surface metabolites as potent antifungal agents.   DOI:  10.1016/j.plaphy.2020.02.026 ;  PMID:  32112998
• Ozone-induced lipid changes in the wildtype and toc132toc120 heterozygote mutant of Arabidopsis thaliana.   DOI:  10.1016/j.plaphy.2020.11.050 ;  PMID:  33291051
• Fatty Acid Desaturases in the Chloroplast and Endoplasmic Reticulum Promote Susceptibility to the Green Peach Aphid Myzus persicae in Arabidopsis thaliana.   DOI:  10.1094/MPMI-12-20-0345-R ;  PMID:  33596108
• A gene encoding a chloroplast omega-3 fatty acid desaturase complements alterations in fatty acid desaturation and chloroplast copy number of the fad7 mutant of Arabidopsis thaliana.   DOI:  S0021-9258(20)80498-0 ;  PMID:  8226956
• Proteomics of the chloroplast envelope membranes from Arabidopsis thaliana.   DOI:  10.1074/mcp.M300030-MCP200 ;  PMID:  12766230
• Proteomic study of the Arabidopsis thaliana chloroplastic envelope membrane utilizing alternatives to traditional two-dimensional electrophoresis.   DOI:  10.1021/pr034025j ;  PMID:  12938931
• Sorting signals, N-terminal modifications and abundance of the chloroplast proteome.   DOI:  10.1371/journal.pone.0001994 ;  PMID:  18431481

Sequences: