Gene Details:

• Gene ID: AT3G07040
• Gene Symbol: RPM1, RPS3
• Gene Name: RESISTANCE TO P. SYRINGAE PV MACULICOLA 1, RESISTANCE TO PSEUDOMONAS SYRINGAE 3
• Description: NB-ARC domain-containing disease resistance protein;(source:Araport11)
• TAIR Accession:
• Genome: Araport11_genome_release
• Species: Arabidopsis thaliana

Transcripts:

• AT3G07040.1

Germplasm Phenotype:

• CS6193  — susceptible to Pseudomonas syringae pv. tomato strain carrying the avirulence gene avrB from the soybean pathogen Pseudomonas syringae pv. glycinea; lacks trichomes on stem and leaves.
• CS67955  — Increased susceptibility to Pseudomonas syringae strains carrying avrB or avrRpm1.
• CS67956  — Increased susceptibility to Pseudomonas syringae strains carrying avrB or avrRpm1.
• CS67957  — Increased susceptibility to Pseudomonas syringae strains carrying avrB or avrRpm1.
• CS68739  — Susceptible to bacterial pathogen Pseudomonas syringae pv. tomato DC3000 (Pto DC3000) carrying the avirulence gene avrRpm1 or avrB.
• CS68740  — Susceptible to bacterial pathogen Pseudomonas syringae pv. tomato DC3000 (Pto DC3000) carrying virulence effector gene avrRpm1, avrB, or avrRpt2.
• CS68746  — Susceptible to bacterial pathogen Pseudomonas syringae pv. tomato DC3000 (Pto DC3000) carrying the avirulence gene avrB. Susceptibility is similar to single mutant rpm1-3 (CS68739).
• CS68760  — Susceptible to pathogen Pto DC3000 carrying virulence effector gene avrRpm1or avrRpt2.
• CS68777  — Lose AvrRpm1-induced cell death. Control for a11 (CS68776).
• CS68778  — No visible phenotype.
• CS68779  — Lose AvrRpm1-induced cell death; reduced RPM1-myc accumulation.
• CS68783  — No visible phenotype.
• CS68789  — No visible phenotype.
• CS68790  — No visible phenotype.
• CS68791  — No visible phenotype.
• CS68792  — No visible phenotype.
• CS68799  — No visible phenotype.
• CS68800  — No visible phenotype.
• CS68801  — No visible phenotype.
• CS68802  — No visible phenotype.
• CS72197  — Full loss-of-function for RPM1 against P. syringae type III effector protein AvrB, and partial loss-of-function for RPM1 against P. syringae type II effector protein AvrRpm1.
• CS72198  — Small, chlorotic plants under long day growth conditions. Gain-of-function for RPM1, up-regulated PR1.
• CS72200  — Suppressed callose accumulation upon flg22 treatment.
• CS72201  — Enhanced callose accumulation upon flg22 treatment. Weak enhanced disease resistance (EDR) phenotype against P. syringae virulence strain DC3000.
• CS72202  — Enhanced callose accumulation upon flg22 treatment. Weak enhanced disease resistance (EDR) phenotype against P. syringae virulence strain DC3000.
• CS72204  — Suppression of callose accumulation upon flg22 treatment. Weak enhanced disease susceptibility (EDS) phenotype against P. syringae virulence strain DC3000.
• CS72205  — Suppression of callose accumulation upon flg22 treatment. Weak enhanced disease susceptibility (EDS) phenotype against P. syringae virulence strain DC3000.
• CS8637  — susceptible to Pseudomonas syringae strains carrying the avirulence genes avrB or avrRpm1

Literature:

• Plant disease resistance genes encode members of an ancient and diverse protein family within the nucleotide-binding superfamily.   DOI:  10.1046/j.1365-313x.1999.t01-1-00606.x ;  PMID:  10571892
• Identification of three putative signal transduction genes involved in R gene-specified disease resistance in Arabidopsis.   DOI:  10.1093/genetics/152.1.401 ;  PMID:  10224270
• Different requirements for EDS1 and NDR1 by disease resistance genes define at least two R gene-mediated signaling pathways in Arabidopsis.   DOI:  10.1073/pnas.95.17.10306 ;  PMID:  9707643
• Isolation of Arabidopsis genes that differentiate between resistance responses mediated by the RPS2 and RPM1 disease resistance genes.   DOI:  10.1105/tpc.8.2.241 ;  PMID:  8742710
• Rapid activation of a novel plant defense gene is strictly dependent on the Arabidopsis RPM1 disease resistance locus.   DOI:  10.1002/j.1460-2075.1992.tb05572.x ;  PMID:  1464303
• Arabidopsis NHO1 is required for general resistance against Pseudomonas bacteria.   DOI:  10.1105/tpc.13.2.437 ;  PMID:  11226196
• A gain-of-function mutation in an Arabidopsis Toll Interleukin1 receptor-nucleotide binding site-leucine-rich repeat type R gene triggers defense responses and results in enhanced disease resistance.   DOI:  10.1105/tpc.005348 ;  PMID:  12468733
• Expression profiling of the host response to bacterial infection: the transition from basal to induced defence responses in RPM1-mediated resistance.   DOI:  10.1046/j.1365-313x.2003.01653.x ;  PMID:  12609040
• Activation of a COI1-dependent pathway in Arabidopsis by Pseudomonas syringae type III effectors and coronatine.   DOI:  10.1111/j.1365-313x.2003.01986.x ;  PMID:  14756769
• A putative nucleoporin 96 Is required for both basal defense and constitutive resistance responses mediated by suppressor of npr1-1,constitutive 1.   DOI:  10.1105/tpc.104.029926 ;  PMID:  15772285
• RIN13 is a positive regulator of the plant disease resistance protein RPM1.   DOI:  10.1105/tpc.104.028720 ;  PMID:  15722472
• Characterization of natural and induced variation in the LOV1 gene, a CC-NB-LRR gene conferring victorin sensitivity and disease susceptibility in Arabidopsis.   DOI:  10.1094/MPMI-21-1-0007 ;  PMID:  18052878
• Constitutive activation of a CC-NB-LRR protein alters morphogenesis through the cytokinin pathway in Arabidopsis.   DOI:  10.1111/j.1365-313X.2008.03466.x ;  PMID:  18315541
• Arabidopsis TAO1 is a TIR-NB-LRR protein that contributes to disease resistance induced by the Pseudomonas syringae effector AvrB.   DOI:  10.1073/pnas.0802157105 ;  PMID:  18424557
• Global analysis of Arabidopsis gene expression uncovers a complex array of changes impacting pathogen response and cell cycle during geminivirus infection.   DOI:  10.1104/pp.108.121038 ;  PMID:  18650403
• The Pseudomonas syringae type III effector AvrRpm1 induces significant defenses by activating the Arabidopsis nucleotide-binding leucine-rich repeat protein RPS2.   DOI:  10.1111/j.1365-313X.2008.03716.x ;  PMID:  18980653
• Combining subproteome enrichment and Rubisco depletion enables identification of low abundance proteins differentially regulated during plant defense.   DOI:  10.1002/pmic.200800293 ;  PMID:  19053141
• Resistance to the Pseudomonas syringae effector HopA1 is governed by the TIR-NBS-LRR protein RPS6 and is enhanced by mutations in SRFR1.   DOI:  10.1104/pp.109.139238 ;  PMID:  19525323
• A protein phosphatase 2C, responsive to the bacterial effector AvrRpm1 but not to the AvrB effector, regulates defense responses in Arabidopsis.   DOI:  10.1111/j.1365-313X.2009.04047.x ;  PMID:  19843314
• Lazarus1, a DUF300 protein, contributes to programmed cell death associated with Arabidopsis acd11 and the hypersensitive response.   DOI:  10.1371/journal.pone.0012586 ;  PMID:  20830211
• Arabidopsis NDR1 is an integrin-like protein with a role in fluid loss and plasma membrane-cell wall adhesion.   DOI:  10.1104/pp.110.169656 ;  PMID:  21398259
• A receptor-like cytoplasmic kinase phosphorylates the host target RIN4, leading to the activation of a plant innate immune receptor.   DOI:  10.1016/j.chom.2011.01.010 ;  PMID:  21320696
• Dynamics of defense responses and cell fate change during Arabidopsis-Pseudomonas syringae interactions.   DOI:  10.1371/journal.pone.0083219 ;  PMID:  24349466
• A restorer-of-fertility like pentatricopeptide repeat gene directs ribonucleolytic processing within the coding sequence of rps3-rpl16 and orf240a mitochondrial transcripts in Arabidopsis thaliana.   DOI:  10.1111/tpj.12463 ;  PMID:  24506331
• The Arabidopsis immune adaptor SRFR1 interacts with TCP transcription factors that redundantly contribute to effector-triggered immunity.   DOI:  10.1111/tpj.12527 ;  PMID:  24689742
• Pseudomonas syringae Effector AvrPphB Suppresses AvrB-Induced Activation of RPM1 but Not AvrRpm1-Induced Activation.   DOI:  10.1094/MPMI-08-14-0248-R ;  PMID:  25625821
• Two N-terminal acetyltransferases antagonistically regulate the stability of a nod-like receptor in Arabidopsis.   DOI:  10.1105/tpc.15.00173 ;  PMID:  25966763
• IBR5 Modulates Temperature-Dependent, R Protein CHS3-Mediated Defense Responses in Arabidopsis.   DOI:  10.1371/journal.pgen.1005584 ;  PMID:  26451844
• Correction: IBR5 Modulates Temperature-Dependent, R Protein CHS3-Mediated Defense Responses in Arabidopsis.   DOI:  10.1371/journal.pgen.1005795 ;  PMID:  26735692
• The Bacterial Effector AvrB-Induced RIN4 Hyperphosphorylation Is Mediated by a Receptor-Like Cytoplasmic Kinase Complex in Arabidopsis.   DOI:  10.1094/MPMI-01-17-0017-R ;  PMID:  28353399
• Translatome analysis of an NB-LRR immune response identifies important contributors to plant immunity in Arabidopsis.   DOI:  10.1093/jxb/erx078 ;  PMID:  28369573
• Comparative Genomics of Non-TNL Disease Resistance Genes from Six Plant Species.   DOI:  10.3390/genes8100249 ;  PMID:  28973974
• Corrigendum: Translatome analysis of an NB-LRR immune response identifies important contributors to plant immunity in Arabidopsis.   DOI:  10.1093/jxb/ery150 ;  PMID:  29878155
• The analogous and opposing roles of double-stranded RNA-binding proteins in bacterial resistance.   DOI:  10.1093/jxb/erz019 ;  PMID:  30843586
• Pathogen-Associated Molecular Pattern-Triggered Immunity Involves Proteolytic Degradation of Core Nonsense-Mediated mRNA Decay Factors During the Early Defense Response.   DOI:  10.1105/tpc.19.00631 ;  PMID:  32086363
• The nuclear localized RIN13 induces cell death through interacting with ARF1.   DOI:  10.1016/j.bbrc.2020.04.082 ;  PMID:  32446355
• RIN13-mediated disease resistance depends on the SNC1-EDS1/PAD4 signaling pathway in Arabidopsis.   DOI:  10.1093/jxb/eraa433 ;  PMID:  32937656
• DELAYED GREENING 409 encodes a dual-localized pentatricopeptide repeat protein required for chloroplast and mitochondrial development.   DOI:  10.1093/plphys/kiad258 ;  PMID:  37096684
• Quantitative phosphoproteomics of early elicitor signaling in Arabidopsis.   DOI:  10.1074/mcp.M600429-MCP200 ;  PMID:  17317660
• Interaction between SGT1 and cytosolic/nuclear HSC70 chaperones regulates Arabidopsis immune responses.   DOI:  10.1105/tpc.107.051896 ;  PMID:  18065690

Sequences: