Gene Details:

• Gene ID: AT3G06030
• Gene Symbol: ANP3, AtANP3, MAPKKK12, NP3
• Gene Name: NPK1-related protein kinase 3, NPK1-related protein kinase 3
• Description: NPK1-related protein kinase 3;(source:Araport11)
• TAIR Accession: locus:2080394
• Genome: Araport11_genome_release
• Species: Arabidopsis thaliana

Transcripts:

• AT3G06030.1

Plant Ontology Annotations:

• PO:0025195  — pollen tube cell — célula del tubo polínico (Spanish, exact), 花粉管細胞 (Japanese, exact)
• PO:0025281  — pollen — polen (Spanish, exact), pollen grain (exact), 花粉 (Japanese, exact)

Gene Ontology:

• GO:0048046  — located in — apoplast
• GO:0004672  — enables — protein kinase activity
• GO:0005886  — located in — plasma membrane
• GO:0004709  — enables — MAP kinase kinase kinase activity
• GO:0006468  — involved in — protein phosphorylation
• GO:0004674  — enables — protein serine/threonine kinase activity
• GO:0043622  — involved in — cortical microtubule organization
• GO:0007165  — involved in — signal transduction
• GO:0043622  — acts upstream of or within — cortical microtubule organization
• GO:0046777  — acts upstream of or within — protein autophosphorylation

Germplasm Phenotype:

• anp2 anp3  — Delayed growth,short roots, multiply branched root hairs.Radially expanded root and hypocotyl cells.Aberrant microtuble organization and resistance to oryzalin.

Function-related keywords:

• pollen tube cell ,  pollen

Literature:

• Possible involvement of differential splicing in regulation of the activity of Arabidopsis ANP1 that is related to mitogen-activated protein kinase kinase kinases (MAPKKKs).   DOI:  10.1046/j.1365-313x.1997.12010039.x ;  PMID:  9263451
• An Arabidopsis mitogen-activated protein kinase kinase kinase gene family encodes essential positive regulators of cytokinesis.   DOI:  10.1105/tpc.001164 ;  PMID:  12034900
• Mitogen-activated protein kinase cascades in plants: a new nomenclature.   DOI:  10.1016/s1360-1385(02)02302-6 ;  PMID:  12119167
• The water-water cycle is essential for chloroplast protection in the absence of stress.   DOI:  10.1074/jbc.M304987200 ;  PMID:  12885779
• A MAPKK kinase gene regulates extra-embryonic cell fate in Arabidopsis.   DOI:  10.1016/s0092-8674(03)01067-5 ;  PMID:  14718171
• Differential binding of calmodulin-related proteins to their targets revealed through high-density Arabidopsis protein microarrays.   DOI:  10.1073/pnas.0611615104 ;  PMID:  17360592
• Elucidating the germination transcriptional program using small molecules.   DOI:  10.1104/pp.107.110841 ;  PMID:  18359847
• Transcriptome analyses show changes in gene expression to accompany pollen germination and tube growth in Arabidopsis.   DOI:  10.1104/pp.108.126375 ;  PMID:  18775970
• and phragmoplast-localized kinase 2 and 3 and mitogen-activated protein kinase 4 are essential for microtubule organization.   DOI:  10.1105/tpc.109.071746 ;  PMID:  20215588
• HINKEL kinesin, ANP MAPKKKs and MKK6/ANQ MAPKK, which phosphorylates and activates MPK4 MAPK, constitute a pathway that is required for cytokinesis in Arabidopsis thaliana.   DOI:  10.1093/pcp/pcq135 ;  PMID:  20802223
• Functional compensation of primary and secondary metabolites by duplicate genes in Arabidopsis thaliana.   DOI:  10.1093/molbev/msq204 ;  PMID:  20736450
• Autophosphorylation profiling of Arabidopsis protein kinases using the cell-free system.   DOI:  10.1016/j.phytochem.2011.02.029 ;  PMID:  21477822
• AND PHRAGMOPLAST-LOCALIZED KINASE1-Related Protein Kinases Are Required for Elicitor-Induced Oxidative Burst and Immunity.   DOI:  10.1104/pp.114.236901 ;  PMID:  24812107
• Proteomic and biochemical analyses show a functional network of proteins involved in antioxidant defense of the Arabidopsis anp2anp3 double mutant.   DOI:  10.1021/pr500588c ;  PMID:  25325904
• Genetic interaction between G2/M phase-specific transcription factor MYB3R4 and MAPKKK ANP3 for execution of cytokinesis in Arabidopsis thaliana.   DOI:  10.4161/15592324.2014.990817 ;  PMID:  25806785
• A double-mutant collection targeting MAP kinase related genes in Arabidopsis for studying genetic interactions.   DOI:  10.1111/tpj.13292 ;  PMID:  27490954
• Loss of the Arabidopsis Protein Kinases ANPs Affects Root Cell Wall Composition, and Triggers the Cell Wall Damage Syndrome.   DOI:  10.3389/fpls.2017.02234 ;  PMID:  29403509
• MKK6 Functions in Two Parallel MAP Kinase Cascades in Immune Signaling.   DOI:  10.1104/pp.18.00592 ;  PMID:  30185442
• The intracellular ROS accumulation in elicitor-induced immunity requires the multiple organelle-targeted Arabidopsis NPK1-related protein kinases.   DOI:  10.1111/pce.13978 ;  PMID:  33314180
• Possible involvement of differential splicing in regulation of the activity of Arabidopsis ANP1 that is related to mitogen-activated protein kinase kinase kinases (MAPKKKs).   DOI:  10.1046/j.1365-313x.1997.12010039.x ;  PMID:  9263451
• Hydroponic isotope labelling of entire plants (HILEP) for quantitative plant proteomics; an oxidative stress case study.   DOI:  10.1016/j.phytochem.2008.04.007 ;  PMID:  18538804

Sequences: