Gene Details:

• Gene ID: AT3G04680
• Gene Symbol: CLPS3
• Gene Name: CLP-similar protein 3
• Description: CLP-similar protein 3;(source:Araport11)
• TAIR Accession: locus:2084938
• Genome: Araport11_genome_release
• Species: Arabidopsis thaliana

Transcripts:

• AT3G04680.1     AT3G04680.2     AT3G04680.3

Gene Ontology:

• GO:0005515  — enables — protein binding
• GO:0010228  — acts upstream of or within — vegetative to reproductive phase transition of meristem
• GO:0006397  — acts upstream of or within — mRNA processing
• GO:0005634  — located in — nucleus
• GO:0051731  — enables — polynucleotide 5-hydroxyl-kinase activity GO:0051731 22523 F transferase activity IBA none PANTHER:PTN000978836|UniProtKB:E7F3I6|UniProtKB:Q5SY16|SGD:S000003958|UniProtKB:Q92989|WB:WBGene00010304 Communication:501741973 2023-06-07 AT3G04680 locus:2084938 AT3G04680 enables polynucleotide 5-hydroxyl-kinase activity
• GO:0006388  — involved in — tRNA splicing, via endonucleolytic cleavage and ligation
• GO:0009908  — acts upstream of or within — flower development
• GO:0005634  — is active in — nucleus
• GO:0048827  — acts upstream of or within — phyllome development
• GO:0006378  — involved in — mRNA polyadenylation
• GO:0005849  — part of — mRNA cleavage factor complex

Germplasm Phenotype:

• clps3-1  — Homozygous clps3-1 mutants cannot be generated. Reciprocal crosses using the gametes from a clps3-1 heterozygote indicate that wild-type and clps3-1 pollen are equally efficient in fertilizing wild type plants. But, there is roughly a 50% reduction in transmission of the clps3-1 mutant female gametophyte. No embryo development can be observed in a presumed homozygote indicating lethality at a very early stage after fertilization. Expression of 35S:CLPS3:TAP rescues the embryo lethality phenotype.

Literature:

• Inactivation of the chloroplast ATP synthase gamma subunit results in high non-photochemical fluorescence quenching and altered nuclear gene expression in Arabidopsis thaliana.   DOI:  10.1074/jbc.M308435200 ;  PMID:  14576160
• Arabidopsis mRNA polyadenylation machinery: comprehensive analysis of protein-protein interactions and gene expression profiling.   DOI:  10.1186/1471-2164-9-220 ;  PMID:  18479511
• Unique features of plant cleavage and polyadenylation specificity factor revealed by proteomic studies.   DOI:  10.1104/pp.109.142729 ;  PMID:  19748916
• Genome-wide identification of EMBRYO-DEFECTIVE (EMB) genes required for growth and development in Arabidopsis.   DOI:  10.1111/nph.16071 ;  PMID:  31334862
• Unique features of plant cleavage and polyadenylation specificity factor revealed by proteomic studies.   DOI:  10.1104/pp.109.142729 ;  PMID:  19748916

Sequences: