AT3G04520

Gene Details

Gene ID: AT3G04520
Gene Symbol: THA2
Gene Name: threonine aldolase 2
Description: threonine aldolase 2;(source:Araport11)
TAIR Accession: locus:2100860
Genome: Araport11_genome_release
Species: Arabidopsis thaliana

Functional Descriptions

GO:0005634 — located in — nucleus
GO:0016829 — enables — lyase activity
GO:0006520 — involved in — amino acid metabolic process
GO:0004793 — enables — threonine aldolase activity
GO:0006567 — involved in — threonine catabolic process
GO:0005829 — is active in — cytosol
GO:0006567 — acts upstream of or within — threonine catabolic process
GO:0006545 — involved in — glycine biosynthetic process
GO:0005829 — located in — cytosol
GO:0008732 — enables — L-allo-threonine aldolase activity

CS6934 — 25% of seeds in developing silique of heterozygous plants are albino and lethal; mature mutant and wild type seeds look identical; but 25% of the developing seedlings are albino, fail to mature beyond the cotyledon stage and do not accumulate any chlorophyll pigments. Mutant growth not rescued with exogenous addition of metabolically related amino acids. Significant alteration in the amino acid profiles of most plant tissue types, increased seed Threonine (Thr) content; reduced Glicyn (a product of Thr aldolase reaction) content in all plant tissues; increased branched-chain amino acids (Ile, Leu and Val) in vegetative tissues, except in stems, where there is a decrease. Reduced levels of organic acids and sugars, citrate and isocitrate levels in seeds and flowers are significantly lower than in wild type; levels of most sugars are significantly decreased in flowers and siliques.
CS6935 — Seeds, seedlings and whole homozygous plants do not show any visible phenotypic differences compared to wild type; not lethal. Analysis of the seed amino acid content show no significant Threonine (Thr) increase compared to wild type; Thr and Ile content in plants is not significantly different from the wild type; reduced levels of organic acids and sugars, citrate and isocitrate levels in seeds and flowers are significantly lower than in wild type.
CS6960 — 25% of seeds in developing silique of heterozygous plants are albino and lethal; mature mutant and wild type seeds look identical; but 25% of the developing seedlings are albino, fail to mature beyond the cotyledon stage and do not accumulate any chlorophyll pigments. Mutant growth not rescued with exogenous addition of metabolically related amino acids. Significant alteration in the amino acid profiles of most plant tissue types, increased seed Threonine (Thr) content; reduced Glicyn (a product of Thr aldolase reaction) content in all plant tissues; increased branched-chain amino acids (Ile, Leu and Val) in vegetative tissues, except in stems, where there is a decrease. Reduced levels of organic acids and sugars, citrate and isocitrate levels in seeds and flowers are significantly lower than in wild type; levels of most sugars are significantly decreased in flowers and siliques.
SAIL_5-CO1 — albino developing seeds. Heterozygous seeds look normal but have moderate increases of threonine and branched-chain amino acids.
SALK_013854 — homozygote plant has no visible phenotype. No significant seed threonine increase either.
SALK_129163 — albino developing seeds. Heterozygous seeds look normal but have moderate increases of threonine and branched-chain amino acids.

Functional Keywords

Literature and News

Gene Resources

Homologs

Sequences

cDNA Sequence

>AT3G04520.1
CACTTATTTGGTTGGACCGATCTTCTTTCTATAAGATTCCCTGTCGTCATTTCGTATTTGATTTGATCACTCATTCTCTCAACCATTTGAGTCACCCGAAGCACATCTCTTTTTATCTCTTCGCCAAGAAAACAAAAAGCATAGCCTAACAGAACAGAATCTAGTGAGCCAAATCAAGATGGTGACGCCAACTACAATTAGAACCGTCGATCTCCGCTCCGACACGGTGACTAAACCAACAGAGTCAATGCGTTCAGCAATGGCAAACGCGGAAGTAGACGACGACGTTTTGGGAAACGATCCAACGGCTCTGCGTTTGGAGAAAGAGGTGGCTGAGATCGCTGGAAAAGAGGCGGCGATGTTTGTTCCGTCAGGGACAATGGGGAATCTGATAAGCGTGTTGGTCCATTGTGATGAGAGAGGGAGTGAAGTGATTCTTGGAGACGACTCTCACATTCATATATATGAAAACGGCGGCGTTTCAAGCCTCGGTGGTGTGCATCCGAGGACGGTGAAGAATGAGGAAGACGGTACGATGGAGATTGGTGCTATTGAAGCTGCCGTGAGGAGTCCCAAAGGAGATCTCCATCATCCGGTTACTAAGCTTATATGTCTTGAGAATACTCAAGCAAATTGTGGAGGTAGATGCCTTCCTATAGAATATATAGACAAAGTCGGAGAATTAGCCAAGAAACATGGTTTGAAGCTTCACATTGACGGAGCTAGGATTTTCAACGCTTCTGTGGCACTTGGAGTTCCCGTGAAGAGGATTGTTCAAGCAGCTGATTCTGTCTCGATCTGTTTGTCGAAAGGTATTGGTGCACCGGTCGGTTCGGTAATCGTGGGAAGCAAGAAGTTCATTACTAAAGCAAGGTGGTTAAGGAAAACATTAGGCGGAGGAATGAGACAGATCGGCGTGCTCTGCGCCGCCGCATTGGTGGCTCTCCATGAAAACGTCGCCAAGCTCGAAGATGACCATAAGAAAGCCAGGGTTTTGGCAGAAGGACTGAACCGGATTGAACGGTTAAGAGTGAACGTTGCAGCTGTGGAAACCAACATCATATACGTAGACATACCAGAAGATCCAAAATTTGGAGCAGAAGAGGCATGTAAGAGCTTGGAAGATGTCGGTGTGCTTGTCATACCCCAAGCTACATTCAGAATCAGGATTGTTCTACACCACCAAATCTCAGACGTCGACGTGGAATATGTACTCTCTTGCTTTGAGAAAATATTTCACTCGTGAAGAGAAGAGAAGGCGTTATTATTTTAAGTAATTTCACTCGTTGGACATGTGTAAGGTTGTATTTGAATCTTCATTCAGAATAAGGTTGTATTTGAATCGATTTTCTTGGTTTACAAATGAAAACCTTTAACCAAGAAGTAGAAAACTCTTTCATCAAATTCACTTATACATATAAATAACCAATTATAACCCAATAATTTATTCTTTATAATCCGATTATTCC
>AT3G04520.2
CACTTATTTGGTTGGACCGATCTTCTTTCTATAAGATTCCCTGTCGTCATTTCGTATTTGATTTGATCACTCATTCTCTCAACCATTTGAGTCACCCGAAGCACATCTCTTTTTATCTCTTCGCCAAGAAAACAAAAAGCATAGCCTAACAGAACAGAATCTAGTGAGCCAAATCAAGATGGTGACGCCAACTACAATTAGAACCGTCGATCTCCGCTCCGACACGGTGACTAAACCAACAGAGTCAATGCGTTCAGCAATGGCAAACGCGGAAGTAGACGACGACGTTTTGGGAAACGATCCAACGGCTCTGCGTTTGGAGAAAGAGGTGGCTGAGATCGCTGGAAAAGAGGCGGCGATGTTTGTTCCGTCAGGGACAATGGGGAATCTGATAAGCGTGTTGGTCCATTGTGATGAGAGAGGGAGTGAAGTGATTCTTGGAGACGACTCTCACATTCATATATATGAAAACGGCGGCGTTTCAAGCCTCGGTGGTGTGCATCCGAGGACGGTGAAGAATGAGGAAGACGGTACGATGGAGATTGGTGCTATTGAAGCTGCCGTGAGGAGTCCCAAAGGAGATCTCCATCATCCGGTTACTAAGCTTATATGTCTTGAGAATACTCAAGCAAATTGTGGAGGTAGATGCCTTCCTATAGAATATATAGACAAAGTCGGAGAATTAGCCAAGAAACATGGTTTGAAGCTTCACATTGACGGAGCTAGGATTTTCAACGCTTCTGTGGCACTTGGAGTTCCCGTGAAGAGGATTGTTCAAGCAGCTGATTCTGTCTCGATCTGTTTGTCGAAAGGTATTGGTGCACCGGTCGGTTCGGTAATCGTGGGAAGCAAGAAGTTCATTACTAAAGCAAGGTGGTTAAGGAAAACATTAGGCGGAGGAATGAGACAGATCGGCGTGCTCTGCGCCGCCGCATTGGTGGCTCTCCATGAAAACGTCGCCAAGCTCGAAGATGACCATAAGAAAGCCAGGGTTTTGGCAGAAGGACTGAACCGGATTGAACGGTTAAGAGTGAACGTTGCAGCTGTGGAAACCAACATCATATACGTAGACATACCAGAAGATCCAAAATTTGGAGCAGAAGAGGCATGTAAGAGCTTGGAAGATGTCGGTGTGCTTGTCATACCCCAAGCTACATTCAGAATCAGGATTGTTCTACACCACCAAATCTCAGACGTCGACGTGGAATATGTACTCTCTTGCTTTGAGAAAATATTTCACTCGTGAAGAGAAGAGAAGGCGTTATTATTTTAAGTAATTTCACTCGTTGGACATGTGTAAGGTTGTATTTGAATCTTCATTCAGAATAAGGTTGTATTTGAATCGATTTTCTTGGTTTACAAATGAAAACCTTTAACCAAGAAGTAGAAAACTCTTTCATCAAATTCACTTATACATATAAATAACCAATTATAACCCAATAATTTATTCTTTATAATCCGATTATTCC
>AT3G04520.3
CACTTATTTGGTTGGACCGATCTTCTTTCTATAAGATTCCCTGTCGTCATTTCGTATTTGATTTGATCACTCATTCTCTCAACCATTTGAGTCACCCGAAGCACATCTCTTTTTATCTCTTCGCCAAGAAAACAAAAAGCATAGCCTAACAGAACAGAATCTAGTGAGCCAAATCAAGATGGTGACGCCAACTACAATTAGAACCGTCGATCTCCGCTCCGACACGGTGACTAAACCAACAGAGTCAATGCGTTCAGCAATGGCAAACGCGGAAGTAGACGACGACGTTTTGGGAAACGATCCAACGGCTCTGCGTTTGGAGAAAGAGGTGGCTGAGATCGCTGGAAAAGAGGCGGCGATGTTTGTTCCGTCAGGGACAATGGGGAATCTGATAAGCGTGTTGGTCCATTGTGATGAGAGAGGGAGTGAAGTGATTCTTGGAGACGACTCTCACATTCATATATATGAAAACGGCGGCGTTTCAAGCCTCGGTGGTGTGCATCCGAGGACGGTGAAGAATGAGGAAGACGGTACGATGGAGATTGGTGCTATTGAAGCTGCCGTGAGGAGTCCCAAAGGAGATCTCCATCATCCGGTTACTAAGCTTATATGTCTTGAGAATACTCAAGCAAATTGTGGAGGTAGATGCCTTCCTATAGAATATATAGACAAAGTCGGAGAATTAGCCAAGAAACATGGTTTGAAGCTTCACATTGACGGAGCTAGGATTTTCAACGCTTCTGTGGCACTTGGAGTTCCCGTGAAGAGGATTGTTCAAGCAGCTGATTCTGTCTCGATCTGTTTGTCGAAAGGTATTGGTGCACCGGTCGGTTCGGTAATCGTGGGAAGCAAGAAGTTCATTACTAAAGCAAGGTGGTTAAGGAAAACATTAGGCGGAGGAATGAGACAGATCGGCGTGCTCTGCGCCGCCGCATTGGTGGCTCTCCATGAAAACGTCGCCAAGCTCGAAGATGACCATAAGAAAGCCAGGGTTTTGGCAGAAGGACTGAACCGGATTGAACGGTTAAGAGTGAACGTTGCAGCTGTGGAAACCAACATCATATACGTAGACATACCAGAAGATCCAAAATTTGGAGCAGAAGAGGCATGTAAGAGCTTGGAAGATGTCGGTGTGCTTGTCATACCCCAAGCTACATTCAGAATCAGGATTGTTCTACACCACCAAATCTCAGACGTCGACGTGGAATATGTACTCTCTTGCTTTGAGAAAATATTTCACTCGTGAAGAGAAGAGAAGGCGTTATTATTTTAAGTAATTTCACTCGTTGGACATGTGTAAGGTTGTATTTGAATCTTCATTCAGAATAAGGTTGTATTTGAATCGATTTTCTTGGTTTACAAATGAAAACCTTTAACCAAGAAGTAGAAAACTCTTTCATCAAATTCACTTATACATATAAATAACCAATTATAACCCAATAATTTATTCTTTATAATCCGATTATTCC

CDS Sequence

>AT3G04520.1
ATGGTGACGCCAACTACAATTAGAACCGTCGATCTCCGCTCCGACACGGTGACTAAACCAACAGAGTCAATGCGTTCAGCAATGGCAAACGCGGAAGTAGACGACGACGTTTTGGGAAACGATCCAACGGCTCTGCGTTTGGAGAAAGAGGTGGCTGAGATCGCTGGAAAAGAGGCGGCGATGTTTGTTCCGTCAGGGACAATGGGGAATCTGATAAGCGTGTTGGTCCATTGTGATGAGAGAGGGAGTGAAGTGATTCTTGGAGACGACTCTCACATTCATATATATGAAAACGGCGGCGTTTCAAGCCTCGGTGGTGTGCATCCGAGGACGGTGAAGAATGAGGAAGACGGTACGATGGAGATTGGTGCTATTGAAGCTGCCGTGAGGAGTCCCAAAGGAGATCTCCATCATCCGGTTACTAAGCTTATATGTCTTGAGAATACTCAAGCAAATTGTGGAGGTAGATGCCTTCCTATAGAATATATAGACAAAGTCGGAGAATTAGCCAAGAAACATGGTTTGAAGCTTCACATTGACGGAGCTAGGATTTTCAACGCTTCTGTGGCACTTGGAGTTCCCGTGAAGAGGATTGTTCAAGCAGCTGATTCTGTCTCGATCTGTTTGTCGAAAGGTATTGGTGCACCGGTCGGTTCGGTAATCGTGGGAAGCAAGAAGTTCATTACTAAAGCAAGGTGGTTAAGGAAAACATTAGGCGGAGGAATGAGACAGATCGGCGTGCTCTGCGCCGCCGCATTGGTGGCTCTCCATGAAAACGTCGCCAAGCTCGAAGATGACCATAAGAAAGCCAGGGTTTTGGCAGAAGGACTGAACCGGATTGAACGGTTAAGAGTGAACGTTGCAGCTGTGGAAACCAACATCATATACGTAGACATACCAGAAGATCCAAAATTTGGAGCAGAAGAGGCATGTAAGAGCTTGGAAGATGTCGGTGTGCTTGTCATACCCCAAGCTACATTCAGAATCAGGATTGTTCTACACCACCAAATCTCAGACGTCGACGTGGAATATGTACTCTCTTGCTTTGAGAAAATATTTCACTCGTGA
>AT3G04520.2
ATGGTGACGCCAACTACAATTAGAACCGTCGATCTCCGCTCCGACACGGTGACTAAACCAACAGAGTCAATGCGTTCAGCAATGGCAAACGCGGAAGTAGACGACGACGTTTTGGGAAACGATCCAACGGCTCTGCGTTTGGAGAAAGAGGTGGCTGAGATCGCTGGAAAAGAGGCGGCGATGTTTGTTCCGTCAGGGACAATGGGGAATCTGATAAGCGTGTTGGTCCATTGTGATGAGAGAGGGAGTGAAGTGATTCTTGGAGACGACTCTCACATTCATATATATGAAAACGGCGGCGTTTCAAGCCTCGGTGGTGTGCATCCGAGGACGGTGAAGAATGAGGAAGACGGTACGATGGAGATTGGTGCTATTGAAGCTGCCGTGAGGAGTCCCAAAGGAGATCTCCATCATCCGGTTACTAAGCTTATATGTCTTGAGAATACTCAAGCAAATTGTGGAGGTAGATGCCTTCCTATAGAATATATAGACAAAGTCGGAGAATTAGCCAAGAAACATGGTTTGAAGCTTCACATTGACGGAGCTAGGATTTTCAACGCTTCTGTGGCACTTGGAGTTCCCGTGAAGAGGATTGTTCAAGCAGCTGATTCTGTCTCGATCTGTTTGTCGAAAGGTATTGGTGCACCGGTCGGTTCGGTAATCGTGGGAAGCAAGAAGTTCATTACTAAAGCAAGGTGGTTAAGGAAAACATTAGGCGGAGGAATGAGACAGATCGGCGTGCTCTGCGCCGCCGCATTGGTGGCTCTCCATGAAAACGTCGCCAAGCTCGAAGATGACCATAAGAAAGCCAGGGTTTTGGCAGAAGGACTGAACCGGATTGAACGGTTAAGAGTGAACGTTGCAGCTGTGGAAACCAACATCATATACGTAGACATACCAGAAGATCCAAAATTTGGAGCAGAAGAGGCATGTAAGAGCTTGGAAGATGTCGGTGTGCTTGTCATACCCCAAGCTACATTCAGAATCAGGATTGTTCTACACCACCAAATCTCAGACGTCGACGTGGAATATGTACTCTCTTGCTTTGAGAAAATATTTCACTCGTGA
>AT3G04520.3
ATGGTGACGCCAACTACAATTAGAACCGTCGATCTCCGCTCCGACACGGTGACTAAACCAACAGAGTCAATGCGTTCAGCAATGGCAAACGCGGAAGTAGACGACGACGTTTTGGGAAACGATCCAACGGCTCTGCGTTTGGAGAAAGAGGTGGCTGAGATCGCTGGAAAAGAGGCGGCGATGTTTGTTCCGTCAGGGACAATGGGGAATCTGATAAGCGTGTTGGTCCATTGTGATGAGAGAGGGAGTGAAGTGATTCTTGGAGACGACTCTCACATTCATATATATGAAAACGGCGGCGTTTCAAGCCTCGGTGGTGTGCATCCGAGGACGGTGAAGAATGAGGAAGACGGTACGATGGAGATTGGTGCTATTGAAGCTGCCGTGAGGAGTCCCAAAGGAGATCTCCATCATCCGGTTACTAAGCTTATATGTCTTGAGAATACTCAAGCAAATTGTGGAGGTAGATGCCTTCCTATAGAATATATAGACAAAGTCGGAGAATTAGCCAAGAAACATGGTTTGAAGCTTCACATTGACGGAGCTAGGATTTTCAACGCTTCTGTGGCACTTGGAGTTCCCGTGAAGAGGATTGTTCAAGCAGCTGATTCTGTCTCGATCTGTTTGTCGAAAGGTATTGGTGCACCGGTCGGTTCGGTAATCGTGGGAAGCAAGAAGTTCATTACTAAAGCAAGGTGGTTAAGGAAAACATTAGGCGGAGGAATGAGACAGATCGGCGTGCTCTGCGCCGCCGCATTGGTGGCTCTCCATGAAAACGTCGCCAAGCTCGAAGATGACCATAAGAAAGCCAGGGTTTTGGCAGAAGGACTGAACCGGATTGAACGGTTAAGAGTGAACGTTGCAGCTGTGGAAACCAACATCATATACGTAGACATACCAGAAGATCCAAAATTTGGAGCAGAAGAGGCATGTAAGAGCTTGGAAGATGTCGGTGTGCTTGTCATACCCCAAGCTACATTCAGAATCAGGATTGTTCTACACCACCAAATCTCAGACGTCGACGTGGAATATGTACTCTCTTGCTTTGAGAAAATATTTCACTCGTGA

Protein Sequence

>AT3G04520.1
MVTPTTIRTVDLRSDTVTKPTESMRSAMANAEVDDDVLGNDPTALRLEKEVAEIAGKEAAMFVPSGTMGNLISVLVHCDERGSEVILGDDSHIHIYENGGVSSLGGVHPRTVKNEEDGTMEIGAIEAAVRSPKGDLHHPVTKLICLENTQANCGGRCLPIEYIDKVGELAKKHGLKLHIDGARIFNASVALGVPVKRIVQAADSVSICLSKGIGAPVGSVIVGSKKFITKARWLRKTLGGGMRQIGVLCAAALVALHENVAKLEDDHKKARVLAEGLNRIERLRVNVAAVETNIIYVDIPEDPKFGAEEACKSLEDVGVLVIPQATFRIRIVLHHQISDVDVEYVLSCFEKIFHS
>AT3G04520.2
MVTPTTIRTVDLRSDTVTKPTESMRSAMANAEVDDDVLGNDPTALRLEKEVAEIAGKEAAMFVPSGTMGNLISVLVHCDERGSEVILGDDSHIHIYENGGVSSLGGVHPRTVKNEEDGTMEIGAIEAAVRSPKGDLHHPVTKLICLENTQANCGGRCLPIEYIDKVGELAKKHGLKLHIDGARIFNASVALGVPVKRIVQAADSVSICLSKGIGAPVGSVIVGSKKFITKARWLRKTLGGGMRQIGVLCAAALVALHENVAKLEDDHKKARVLAEGLNRIERLRVNVAAVETNIIYVDIPEDPKFGAEEACKSLEDVGVLVIPQATFRIRIVLHHQISDVDVEYVLSCFEKIFHS
>AT3G04520.3
MVTPTTIRTVDLRSDTVTKPTESMRSAMANAEVDDDVLGNDPTALRLEKEVAEIAGKEAAMFVPSGTMGNLISVLVHCDERGSEVILGDDSHIHIYENGGVSSLGGVHPRTVKNEEDGTMEIGAIEAAVRSPKGDLHHPVTKLICLENTQANCGGRCLPIEYIDKVGELAKKHGLKLHIDGARIFNASVALGVPVKRIVQAADSVSICLSKGIGAPVGSVIVGSKKFITKARWLRKTLGGGMRQIGVLCAAALVALHENVAKLEDDHKKARVLAEGLNRIERLRVNVAAVETNIIYVDIPEDPKFGAEEACKSLEDVGVLVIPQATFRIRIVLHHQISDVDVEYVLSCFEKIFHS