Gene Details:

• Gene ID: AT3G04340
• Gene Symbol: EMB2458, FtsHi5, TSL2
• Gene Name: EMBRYO DEFECTIVE 2458, (Filamentation temperature-sensitive H)-like 5, thermo-sensitive mutant in leaf color 2
• Description: FtsH extracellular protease family;(source:Araport11)
• TAIR Accession: locus:2103055
• Genome: Araport11_genome_release
• Species: Arabidopsis thaliana

Transcripts:

• AT3G04340.1

Gene Ontology:

• GO:0005515  — enables — protein binding
• GO:0009941  — located in — chloroplast envelope
• GO:0004176  — enables — ATP-dependent peptidase activity
• GO:0009534  — is active in — chloroplast thylakoid
• GO:0009941  — colocalizes with — chloroplast envelope
• GO:0005829  — located in — cytosol
• GO:0016887  — enables — ATP hydrolysis activity
• GO:0009706  — located in — chloroplast inner membrane
• GO:0009507  — located in — chloroplast
• GO:0009658  — acts upstream of or within — chloroplast organization
• GO:0004222  — enables — metalloendopeptidase activity
• GO:0009793  — acts upstream of or within — embryo development ending in seed dormancy
• GO:0045037  — acts upstream of or within — protein import into chloroplast stroma
• GO:0045454  — acts upstream of or within — cell redox homeostasis
• GO:0016464  — enables — chloroplast protein-transporting ATPase activity
• GO:0080093  — acts upstream of or within — regulation of photorespiration
• GO:0009506  — located in — plasmodesma

Germplasm Phenotype:

• pr1  — Chlorotic, curled and smaller leaves. Higher H2O2 contents.

Literature:

• Inactivation of the chloroplast ATP synthase gamma subunit results in high non-photochemical fluorescence quenching and altered nuclear gene expression in Arabidopsis thaliana.   DOI:  10.1074/jbc.M308435200 ;  PMID:  14576160
• Identification of genes required for embryo development in Arabidopsis.   DOI:  10.1104/pp.104.045179 ;  PMID:  15266054
• Identification of nuclear genes encoding chloroplast-localized proteins required for embryo development in Arabidopsis.   DOI:  10.1104/pp.110.168120 ;  PMID:  21139083
• FtsH proteases located in the plant chloroplast.   DOI:  10.1111/j.1399-3054.2011.01548.x ;  PMID:  22121866
• Nitrogen remobilization during leaf senescence: lessons from Arabidopsis to crops.   DOI:  10.1093/jxb/erw365 ;  PMID:  27707774
• Plastidial NAD-Dependent Malate Dehydrogenase: A Moonlighting Protein Involved in Early Chloroplast Development through Its Interaction with an FtsH12-FtsHi Protease Complex.   DOI:  10.1105/tpc.18.00121 ;  PMID:  29934433
• A Ycf2-FtsHi Heteromeric AAA-ATPase Complex Is Required for Chloroplast Protein Import.   DOI:  10.1105/tpc.18.00357 ;  PMID:  30309901
• Reduced expression of the proteolytically inactive FtsH members has impacts on the Darwinian fitness of Arabidopsis thaliana.   DOI:  10.1093/jxb/erz004 ;  PMID:  30721974
• Genome-wide identification of EMBRYO-DEFECTIVE (EMB) genes required for growth and development in Arabidopsis.   DOI:  10.1111/nph.16071 ;  PMID:  31334862
• The FtsH-Inactive Protein FtsHi5 Is Required for Chloroplast Development and Protein Accumulation in Chloroplasts at Low Ambient Temperature in Arabidopsis.   DOI:  10.3389/fpls.2021.830390 ;  PMID:  35185971
• Proteomic study of the Arabidopsis thaliana chloroplastic envelope membrane utilizing alternatives to traditional two-dimensional electrophoresis.   DOI:  10.1021/pr034025j ;  PMID:  12938931
• Sorting signals, N-terminal modifications and abundance of the chloroplast proteome.   DOI:  10.1371/journal.pone.0001994 ;  PMID:  18431481

Sequences: