Gene Details:

• Gene ID: AT2G44990
• Gene Symbol: ATCCD7, CCD7, MAX3
• Gene Name: carotenoid cleavage dioxygenase 7
• Description: carotenoid cleavage dioxygenase 7;(source:Araport11)
• TAIR Accession:
• Genome: Araport11_genome_release
• Species: Arabidopsis thaliana

Transcripts:

• AT2G44990.1     AT2G44990.3     AT2G44990.2

Plant Ontology Annotations:

• PO:0000037  — shoot axis apex — ápice del epiblasto (epiblastema) (Spanish, exact), シュート頂、茎頂 (Japanese, exact)
• PO:0008019  — leaf lamina base — base de la lámina de la hoja (Spanish, exact), 葉身基部 (Japanese, exact)
• PO:0009005  — root — raíz (Spanish, exact), radices (exact, plural), radix (exact), 根 (Japanese, exact), aerial root (narrow), climbing root (narrow)
• PO:0009009  — plant embryo — embrión (Spanish, exact), 植物胚 (Japanese, exact), germ (related), embryo (broad)
• PO:0009025  — vascular leaf — foliage leaf (exact), hoja vascular (Spanish, exact), leaf, vascular (exact), vascular leaves (exact, plural), 維管束のある葉, または維管束植物の葉 (Japanese, exact), crozier (related), macrophyll (related), megaphyll (related), ascidia (narrow), ascidium (narrow), fiddlehead (narrow), frond (narrow), needle-like leaf (narrow), pitcher (narrow), pitcher blade (narrow), pitcher-blade (narrow), scale-like leaf (narrow), sterile frond (narrow), trophophyll (narrow)
• PO:0009029  — stamen — estambre (Spanish, exact), 雄蕊 (Japanese, exact), Poaceae stamen (narrow), Zea stamen (narrow)
• PO:0009031  — sepal — sépalo (Spanish, exact), がく片 (Japanese, exact)
• PO:0009046  — flower — flor (Spanish, exact), 花 (Japanese, exact), floret (related), Asteraceae floret (narrow), basal flower (narrow), double flower (narrow), hermaphrodite flower (narrow), monoclinous flower (narrow), perfect flower (narrow)
• PO:0009052  — inflorescence flower pedicel — 小花柄 (Japanese, related), pedicelo (Spanish, broad)
• PO:0020030  — cotyledon — cotiledón (Spanish, exact), seed leaf (exact), 子葉 (Japanese, exact)
• PO:0020038  — petiole — pecíolo (Spanish, exact), 葉柄 (Japanese, exact)
• PO:0020100  — hypocotyl — hipocótile (Spanish, exact), 胚軸 (Japanese, exact)
• PO:0020137  — leaf apex — ápice de la hoja (Spanish, exact), 葉先 (Japanese, exact), leaf lamina apex (narrow), phyllid apex (narrow)
• PO:0025022  — collective leaf structure — estructura colectiva de hoja (Spanish, exact), leaf series (exact), 葉が集まった構造 (Japanese, exact), leaf whorl (narrow), rosette (narrow), cycle (broad), verticil (broad)
• PO:0025281  — pollen — polen (Spanish, exact), pollen grain (exact), 花粉 (Japanese, exact)
• PO:0009001  — fruit — frucht (exact, German), fruto (exact, Spanish), 果実 (exact, Japanese), coenocarp (narrow), syncarp (narrow), aggregate fruit (broad), compound fruit (broad), dehiscent fruit (broad), diaspore (broad), indehiscent fruit (broad), multiple fruit (broad), propagule (broad)
• PO:0009047  — stem — caña (Spanish, exact), culm (exact), eje primario (Spanish, exact), primary axis (exact), primary stem (exact), tallo (Spanish, exact), tronco (Spanish, exact), 茎 (Japanese, exact), bole (narrow), cane (narrow), caudex (narrow), caudices (narrow), core (narrow), primocane (narrow), scape (narrow), stalk (narrow), trunk (narrow)
• PO:0000084  — plant sperm cell — célula espermática o esperma (Spanish, exact), male gamete (exact), microgamete (exact), 植物精子細胞 (Japanese, exact), sperm nucleus (related), sperm cell (broad)

Germplasm Phenotype:

• CS9567  — bushy appearance due to increased axillary branching; reduced height; reduced petiole and leaf length
• MAX3:max3-11 MAX4:max4-6  — Slight increase in inflorescence number compared with wild type.
• max3-10  — 80% of wild type height at maturity. Leaves and petioles are shorter than wild type.
• max3-10  — Bushy appearance due to an increase in primary and secondary order branching.
• max3-10  — Endogenous levels of IAA and ABA are slightly higher than in wild type but differences were not significant.
• max3-11 bps1-2  — Double mutants were indistinguishable from bps1 single mutants.
• max3-11 max4-6  — Double mutant is phenotypically indistinguishable from either single mutant.
• max3-3  — 80% of wild type height at maturity. Leaves and petioles are shorter than wild type.
• max3-3  — Bushy appearance due to an increase in primary and secondary order branching.
• max3-4  — 80% of wild type height at maturity. Leaves and petioles are shorter than wild type.
• max3-4  — Bushy appearance due to an increase in primary and secondary order branching.
• max3-9  — 80% of wild type height at maturity. Leaves and petioles are shorter than wild type.
• max3-9  — Bushy appearance due to an increase in primary and secondary order branching.

Function-related keywords:

• shoot axis apex ,  leaf lamina base ,  root ,  plant embryo ,  vascular leaf ,  stamen ,  sepal ,  flower ,  inflorescence flower pedicel ,  cotyledon ,  petiole ,  hypocotyl ,  leaf apex ,  collective leaf structure ,  pollen ,  fruit ,  root ,  vascular leaf ,  flower ,  stem ,  petiole ,  plant sperm cell

Literature:

• Micrografting techniques for testing long-distance signalling in Arabidopsis.   DOI:  10.1046/j.1365-313x.2002.01419.x ;  PMID:  12383090
• MAX3/CCD7 is a carotenoid cleavage dioxygenase required for the synthesis of a novel plant signaling molecule.   DOI:  10.1016/j.cub.2004.06.061 ;  PMID:  15268852
• MAX1 encodes a cytochrome P450 family member that acts downstream of MAX3/4 to produce a carotenoid-derived branch-inhibiting hormone.   DOI:  10.1016/j.devcel.2005.01.009 ;  PMID:  15737939
• Characterization of three members of the Arabidopsis carotenoid cleavage dioxygenase family demonstrates the divergent roles of this multifunctional enzyme family.   DOI:  10.1111/j.1365-313X.2006.02666.x ;  PMID:  16507088
• Branching genes are conserved across species. Genes controlling a novel signal in pea are coregulated by other long-distance signals.   DOI:  10.1104/pp.106.087676 ;  PMID:  16980559
• The rice HIGH-TILLERING DWARF1 encoding an ortholog of Arabidopsis MAX3 is required for negative regulation of the outgrowth of axillary buds.   DOI:  10.1111/j.1365-313X.2006.02916.x ;  PMID:  17092317
• MAX2 participates in an SCF complex which acts locally at the node to suppress shoot branching.   DOI:  10.1111/j.1365-313X.2007.03032.x ;  PMID:  17346265
• The genetic architecture of shoot branching in Arabidopsis thaliana: a comparative assessment of candidate gene associations vs. quantitative trait locus mapping.   DOI:  10.1534/genetics.107.071928 ;  PMID:  17435248
• Promoter DNA hypermethylation and gene repression in undifferentiated Arabidopsis cells.   DOI:  10.1371/journal.pone.0003306 ;  PMID:  18827894
• Carotenoid oxygenases involved in plant branching catalyse a highly specific conserved apocarotenoid cleavage reaction.   DOI:  10.1042/BJ20080568 ;  PMID:  18637791
• Interactions between auxin and strigolactone in shoot branching control.   DOI:  10.1104/pp.109.137646 ;  PMID:  19641034
• Over-expression of the IGI1 leading to altered shoot-branching development related to MAX pathway in Arabidopsis.   DOI:  10.1007/s11103-010-9645-0 ;  PMID:  20473553
• Modified CAROTENOID CLEAVAGE DIOXYGENASE8 expression correlates with altered branching in kiwifruit (Actinidia chinensis).   DOI:  10.1111/j.1469-8137.2010.03394.x ;  PMID:  20659299
• Vascular-specific activity of the Arabidopsis carotenoid cleavage dioxygenase 7 gene promoter.   DOI:  10.1007/s00299-010-0999-1 ;  PMID:  21243360
• The path from β-carotene to carlactone, a strigolactone-like plant hormone.   DOI:  10.1126/science.1218094 ;  PMID:  22422982
• The Arabidopsis ortholog of rice DWARF27 acts upstream of MAX1 in the control of plant development by strigolactones.   DOI:  10.1104/pp.112.196253 ;  PMID:  22623516
• A novel antilithiatic protein from Tribulus terrestris having cytoprotective potency.   DOI:  10.2174/092986612801619552 ;  PMID:  22702898
• Arabidopsis mutant sk156 reveals complex regulation of SPL15 in a miR156-controlled gene network.   DOI:  10.1186/1471-2229-12-169 ;  PMID:  22989211
• Selective mimics of strigolactone actions and their potential use for controlling damage caused by root parasitic weeds.   DOI:  10.1093/mp/sss138 ;  PMID:  23204501
• Effects of strigolactone-biosynthesis inhibitor TIS108 on Arabidopsis.   DOI:  10.4161/psb.24193 ;  PMID:  23511201
• Carotenoid cleavage dioxygenase 7 modulates plant growth, reproduction, senescence, and determinate nodulation in the model legume Lotus japonicus.   DOI:  10.1093/jxb/ert056 ;  PMID:  23567864
• MAX2 affects multiple hormones to promote photomorphogenesis.   DOI:  10.1093/mp/sss029 ;  PMID:  22466576
• Regulation of drought tolerance by the F-box protein MAX2 in Arabidopsis.   DOI:  10.1104/pp.113.226837 ;  PMID:  24198318
• Carlactone is an endogenous biosynthetic precursor for strigolactones.   DOI:  10.1073/pnas.1314805111 ;  PMID:  24434551
• and stereospecificity of the plant carotenoid cleavage dioxygenase 7.   DOI:  10.1016/j.febslet.2014.03.041 ;  PMID:  24685691
• Strigolactone Regulates Leaf Senescence in Concert with Ethylene in Arabidopsis.   DOI:  10.1104/pp.15.00325 ;  PMID:  25979917
• Strigolactones as an auxiliary hormonal defence mechanism against leafy gall syndrome in Arabidopsis thaliana.   DOI:  10.1093/jxb/erv309 ;  PMID:  26136271
• Biochemical characterization and selective inhibition of β-carotene cis-trans isomerase D27 and carotenoid cleavage dioxygenase CCD8 on the strigolactone biosynthetic pathway.   DOI:  10.1111/febs.13400 ;  PMID:  26257333
• Strigolactone Signaling in Arabidopsis Regulates Shoot Development by Targeting D53-Like SMXL Repressor Proteins for Ubiquitination and Degradation.   DOI:  10.1105/tpc.15.00605 ;  PMID:  26546446
• Effects of strigolactone signaling on Arabidopsis growth under nitrogen deficient stress condition.   DOI:  10.1080/15592324.2015.1126031 ;  PMID:  26653175
• Enzymatic study on AtCCD4 and AtCCD7 and their potential to form acyclic regulatory metabolites.   DOI:  10.1093/jxb/erw356 ;  PMID:  27811075
• Molecular Modeling and Dynamic Simulation of Arabidopsis Thaliana Carotenoid Cleavage Dioxygenase Gene: A Comparison with Bixa orellana and Crocus Sativus.   DOI:  10.1002/jcb.25919 ;  PMID:  28145590
• Largely additive effects of gibberellin and strigolactone on gene expression in Arabidopsis thaliana seedlings.   DOI:  10.1111/tpj.13729 ;  PMID:  28977719
• Expression of MdCCD7 in the scion determines the extent of sylleptic branching and the primary shoot growth rate of apple trees.   DOI:  10.1093/jxb/erx404 ;  PMID:  29190381
• Functional characterization of soybean strigolactone biosynthesis and signaling genes in Arabidopsis MAX mutants and GmMAX3 in soybean nodulation.   DOI:  10.1186/s12870-017-1182-4 ;  PMID:  29268717
• The Arabidopsis DWARF27 gene encodes an all-trans-/9-cis-β-carotene isomerase and is induced by auxin, abscisic acid and phosphate deficiency.   DOI:  10.1016/j.plantsci.2018.06.024 ;  PMID:  30466598
• Molecular dialogue between arbuscular mycorrhizal fungi and the nonhost plant Arabidopsis thaliana switches from initial detection to antagonism.   DOI:  10.1111/nph.15798 ;  PMID:  30883790
• Strigolactone Signaling Genes Showing Differential Expression Patterns in Arabidopsis max Mutants.   DOI:  10.3390/plants8090352 ;  PMID:  31546850
• Prolonged cold exposure to Arabidopsis juvenile seedlings extends vegetative growth and increases the number of shoot branches.   DOI:  10.1080/15592324.2020.1789320 ;  PMID:  32631114
• Genetic dissection of cell wall defects and the strigolactone pathway in Arabidopsis.   DOI:  10.1002/pld3.149 ;  PMID:  31245785
• Strigolactones Interact With Nitric Oxide in Regulating Root System Architecture of Arabidopsis thaliana.   DOI:  10.3389/fpls.2020.01019 ;  PMID:  32719710
• Strigolactone mimic 2-nitrodebranone is highly active in Arabidopsis growth and development.   DOI:  10.1111/tpj.15274 ;  PMID:  33860570
• Cytosine methylation of the FWA promoter promotes direct in vitro shoot regeneration in Arabidopsis thaliana.   DOI:  10.1111/jipb.13156 ;  PMID:  34292662
• Synthetic Strigolactone GR24 Improves Arabidopsis Somatic Embryogenesis through Changes in Auxin Responses.   DOI:  10.3390/plants10122720 ;  PMID:  34961192
• Micrografting techniques for testing long-distance signalling in Arabidopsis.   DOI:  10.1046/j.1365-313x.2002.01419.x ;  PMID:  12383090
• The genetic architecture of shoot branching in Arabidopsis thaliana: a comparative assessment of candidate gene associations vs. quantitative trait locus mapping.   DOI:  10.1534/genetics.107.071928 ;  PMID:  17435248

Sequences: