Gene Details:

• Gene ID: AT2G43710
• Gene Symbol: AtSSI2, FAB2, LDW1, SSI2
• Gene Name: FATTY ACID BIOSYNTHESIS 2, lesion dwarf mimic 1, suppressor of SA insensitive 2
• Description:
• TAIR Accession: locus:2043899
• Genome: Araport11_genome_release
• Species: Arabidopsis thaliana

Transcripts:

Plant Ontology Annotations:

• PO:0000037  — shoot axis apex — ápice del epiblasto (epiblastema) (Spanish, exact), シュート頂、茎頂 (Japanese, exact)
• PO:0008019  — leaf lamina base — base de la lámina de la hoja (Spanish, exact), 葉身基部 (Japanese, exact)
• PO:0009005  — root — raíz (Spanish, exact), radices (exact, plural), radix (exact), 根 (Japanese, exact), aerial root (narrow), climbing root (narrow)
• PO:0009006  — shoot system — sistema de epiblasto (epiblastema) (Spanish, exact), シュート系、苗条系 (Japanese, exact), Poaceae crown (related), shoot (related), thalli (related), thallus (related), tree crown (narrow)
• PO:0009009  — plant embryo — embrión (Spanish, exact), 植物胚 (Japanese, exact), germ (related), embryo (broad)
• PO:0009025  — vascular leaf — foliage leaf (exact), hoja vascular (Spanish, exact), leaf, vascular (exact), vascular leaves (exact, plural), 維管束のある葉, または維管束植物の葉 (Japanese, exact), crozier (related), macrophyll (related), megaphyll (related), ascidia (narrow), ascidium (narrow), fiddlehead (narrow), frond (narrow), needle-like leaf (narrow), pitcher (narrow), pitcher blade (narrow), pitcher-blade (narrow), scale-like leaf (narrow), sterile frond (narrow), trophophyll (narrow)
• PO:0009029  — stamen — estambre (Spanish, exact), 雄蕊 (Japanese, exact), Poaceae stamen (narrow), Zea stamen (narrow)
• PO:0009031  — sepal — sépalo (Spanish, exact), がく片 (Japanese, exact)
• PO:0009046  — flower — flor (Spanish, exact), 花 (Japanese, exact), floret (related), Asteraceae floret (narrow), basal flower (narrow), double flower (narrow), hermaphrodite flower (narrow), monoclinous flower (narrow), perfect flower (narrow)
• PO:0009052  — inflorescence flower pedicel — 小花柄 (Japanese, related), pedicelo (Spanish, broad)
• PO:0020030  — cotyledon — cotiledón (Spanish, exact), seed leaf (exact), 子葉 (Japanese, exact)
• PO:0020038  — petiole — pecíolo (Spanish, exact), 葉柄 (Japanese, exact)
• PO:0020100  — hypocotyl — hipocótile (Spanish, exact), 胚軸 (Japanese, exact)
• PO:0020137  — leaf apex — ápice de la hoja (Spanish, exact), 葉先 (Japanese, exact), leaf lamina apex (narrow), phyllid apex (narrow)
• PO:0025022  — collective leaf structure — estructura colectiva de hoja (Spanish, exact), leaf series (exact), 葉が集まった構造 (Japanese, exact), leaf whorl (narrow), rosette (narrow), cycle (broad), verticil (broad)
• PO:0025281  — pollen — polen (Spanish, exact), pollen grain (exact), 花粉 (Japanese, exact)

Gene Ontology:

• GO:0009570  — located in — chloroplast stroma
• GO:0006636  — acts upstream of or within — unsaturated fatty acid biosynthetic process
• GO:0006631  — acts upstream of or within — fatty acid metabolic process
• GO:0004768  — enables — stearoyl-CoA 9-desaturase activity
• GO:0009507  — located in — chloroplast
• GO:0042742  — acts upstream of or within — defense response to bacterium
• GO:0002213  — acts upstream of or within — defense response to insect
• GO:0051607  — acts upstream of or within — defense response to virus
• GO:0006631  — involved in — fatty acid metabolic process
• GO:0009534  — located in — chloroplast thylakoid
• GO:0009536  — located in — plastid
• GO:0008610  — acts upstream of or within — lipid biosynthetic process
• GO:2000022  — acts upstream of or within — regulation of jasmonic acid mediated signaling pathway
• GO:0045300  — enables — acyl-[acyl-carrier-protein] desaturase activity
• GO:0006952  — involved in — defense response
• GO:2000031  — acts upstream of or within — regulation of salicylic acid mediated signaling pathway
• GO:0102786  — enables — stearoyl-[acp] desaturase activity
• GO:0009695  — acts upstream of or within — jasmonic acid biosynthetic process
• GO:0006952  — acts upstream of or within — defense response

Germplasm Phenotype:

• aad1 aad5 aad6 fab2  — Increased proportions of C18:0 and their elongated derivatives (C20:0 and C22:0), concomitantly decreased levels of &
• aad1 aad5 fab2  — Increased proportions of C18:0 and their elongated derivatives (C20:0 and C22:0), concomitantly decreased levels of &
• aad5 fab2  — Increased proportions of C18:0 and their elongated derivatives (C20:0 and C22:0), concomitantly decreased levels of &
• ssi2  — Spontaneous lesions, enhanced resistance to P. parasitica
• ssi2  — dwarf with crinkled leaves. conferred hyper-resistance to green peach aphid.
• ssi2-4  — Soil-grown ssi2-4 mutant plants exhibit dwarf phenotype and constitutively express the ER molecular chaperone BiP3.

Function-related keywords:

• shoot axis apex ,  leaf lamina base ,  root ,  shoot system ,  plant embryo ,  vascular leaf ,  stamen ,  sepal ,  flower ,  inflorescence flower pedicel ,  cotyledon ,  petiole ,  hypocotyl ,  leaf apex ,  collective leaf structure ,  pollen

Literature:

• and NPR1-independent expression of PR genes and resistance against bacterial and oomycete pathogens.   DOI:  10.1046/j.1365-313x.2001.00992.x ;  PMID:  11309146
• A fatty acid desaturase modulates the activation of defense signaling pathways in plants.   DOI:  10.1073/pnas.151258398 ;  PMID:  11481500
• A Mutant of Arabidopsis with Increased Levels of Stearic Acid.   DOI:  10.1104/pp.106.4.1443 ;  PMID:  12232421
• Arabidopsis sfd mutants affect plastidic lipid composition and suppress dwarfing, cell death, and the enhanced disease resistance phenotypes resulting from the deficiency of a fatty acid desaturase.   DOI:  10.1105/tpc.015529 ;  PMID:  14507997
• and jasmonic acid-mediated defense pathways in the Arabidopsis ssi2 mutant.   DOI:  10.1105/tpc.017301 ;  PMID:  14615603
• Restoration of defective cross talk in ssi2 mutants: role of salicylic acid, jasmonic acid, and fatty acids in SSI2-mediated signaling.   DOI:  10.1094/MPMI.2003.16.11.1022 ;  PMID:  14601670
• Oleic acid levels regulated by glycerolipid metabolism modulate defense gene expression in Arabidopsis.   DOI:  10.1073/pnas.0401315101 ;  PMID:  15044700
• Enhanced resistance to Cucumber mosaic virus in the Arabidopsis thaliana ssi2 mutant is mediated via an SA-independent mechanism.   DOI:  10.1094/MPMI.2004.17.6.623 ;  PMID:  15195945
• and rrt-mediated resistance to turnip crinkle virus in Arabidopsis.   DOI:  10.1111/j.1365-313X.2004.02241.x ;  PMID:  15546349
• Arabidopsis ssi2-conferred susceptibility to Botrytis cinerea is dependent on EDS5 and PAD4.   DOI:  10.1094/MPMI-18-0363 ;  PMID:  15828688
• Role of salicylic acid and fatty acid desaturation pathways in ssi2-mediated signaling.   DOI:  10.1104/pp.105.071662 ;  PMID:  16306139
• The Arabidopsis stearoyl-acyl carrier protein-desaturase family and the contribution of leaf isoforms to oleic acid synthesis.   DOI:  10.1007/s11103-006-9086-y ;  PMID:  17072561
• Plastidial fatty acid levels regulate resistance gene-dependent defense signaling in Arabidopsis.   DOI:  10.1073/pnas.0609259104 ;  PMID:  17431038
• An oleic acid-mediated pathway induces constitutive defense signaling and enhanced resistance to multiple pathogens in soybean.   DOI:  10.1094/MPMI-21-5-0564 ;  PMID:  18393616
• Global analysis of Arabidopsis gene expression uncovers a complex array of changes impacting pathogen response and cell cycle during geminivirus infection.   DOI:  10.1104/pp.108.121038 ;  PMID:  18650403
• Suppression of the rice fatty-acid desaturase gene OsSSI2 enhances resistance to blast and leaf blight diseases in rice.   DOI:  10.1094/MPMI-22-7-0820 ;  PMID:  19522564
• Heterologous expression of stearoyl-acyl carrier protein desaturase (S-ACP-DES) from Arabidopsis thaliana in Escherichia coli.   DOI:  10.1016/j.pep.2009.08.011 ;  PMID:  19716420
• Systems analysis of seed filling in Arabidopsis: using general linear modeling to assess concordance of transcript and protein expression.   DOI:  10.1104/pp.109.152413 ;  PMID:  20118269
• Low oleic acid-derived repression of jasmonic acid-inducible defense responses requires the WRKY50 and WRKY51 proteins.   DOI:  10.1104/pp.110.166876 ;  PMID:  21030507
• Antibiosis against the green peach aphid requires the Arabidopsis thaliana MYZUS PERSICAE-INDUCED LIPASE1 gene.   DOI:  10.1111/j.1365-313X.2010.04378.x ;  PMID:  21105927
• Isolation and characterization of fatty acid desaturase genes from peanut (Arachis hypogaea L.).   DOI:  10.1007/s00299-011-1048-4 ;  PMID:  21409552
• Towards the genetic architecture of seed lipid biosynthesis and accumulation in Arabidopsis thaliana.   DOI:  10.1038/hdy.2011.54 ;  PMID:  21731053
• Oleic acid-dependent modulation of NITRIC OXIDE ASSOCIATED1 protein levels regulates nitric oxide-mediated defense signaling in Arabidopsis.   DOI:  10.1105/tpc.112.096768 ;  PMID:  22492810
• Acyl-lipid metabolism.   DOI:  10.1199/tab.0161 ;  PMID:  23505340
• Overexpression of a wheat stearoyl-ACP desaturase (SACPD) gene TaSSI2 in Arabidopsis ssi2 mutant compromise its resistance to powdery mildew.   DOI:  10.1016/j.gene.2013.04.019 ;  PMID:  23624392
• Characterization of a stearoyl-acyl carrier protein desaturase gene family from chocolate tree, Theobroma cacao L.   DOI:  10.3389/fpls.2015.00239 ;  PMID:  25926841
• ACYL-ACYL CARRIER PROTEIN DESATURASE2 and 3 Are Responsible for Making Omega-7 Fatty Acids in the Arabidopsis Aleurone.   DOI:  10.1104/pp.16.00836 ;  PMID:  27462083
• A bioassay-guided fractionation system to identify endogenous small molecules that activate plasma membrane H+-ATPase activity in Arabidopsis.   DOI:  10.1093/jxb/erx156 ;  PMID:  28582540
• A novel mutant allele of SSI2 confers a better balance between disease resistance and plant growth inhibition on Arabidopsis thaliana.   DOI:  10.1186/s12870-016-0898-x ;  PMID:  27669891
• Constitutive BiP protein accumulation in Arabidopsis mutants defective in a gene encoding chloroplast-resident stearoyl-acyl carrier protein desaturase.   DOI:  10.1111/gtc.12585 ;  PMID:  29688606
• CYP720A1 function in roots is required for flowering time and systemic acquired resistance in the foliage of Arabidopsis.   DOI:  10.1093/jxb/eraa374 ;  PMID:  32793967
• Differential Activation of Partially Redundant Δ9 Stearoyl-ACP Desaturase Genes Is Critical for Omega-9 Monounsaturated Fatty Acid Biosynthesis During Seed Development in Arabidopsis.   DOI:  10.1105/tpc.20.00554 ;  PMID:  32958563
• Fatty Acid Desaturases in the Chloroplast and Endoplasmic Reticulum Promote Susceptibility to the Green Peach Aphid Myzus persicae in Arabidopsis thaliana.   DOI:  10.1094/MPMI-12-20-0345-R ;  PMID:  33596108
• Characterization of fab2 T-DNA insertion mutants in terms of fatty acid composition and plant phenotype.   DOI:  10.1080/15592324.2023.2213937 ;  PMID:  37204036
• A fatty acid desaturase modulates the activation of defense signaling pathways in plants.   DOI:  10.1073/pnas.151258398 ;  PMID:  11481500
• A Mutant of Arabidopsis with Increased Levels of Stearic Acid.   DOI:  10.1104/pp.106.4.1443 ;  PMID:  12232421
• Sorting signals, N-terminal modifications and abundance of the chloroplast proteome.   DOI:  10.1371/journal.pone.0001994 ;  PMID:  18431481
• Quantitative proteomics of a chloroplast SRP54 sorting mutant and its genetic interactions with CLPC1 in Arabidopsis.   DOI:  10.1104/pp.108.124545 ;  PMID:  18633119
• The oligomeric stromal proteome of Arabidopsis thaliana chloroplasts.   DOI:  10.1074/mcp.M500180-MCP200 ;  PMID:  16207701
• Sorting signals, N-terminal modifications and abundance of the chloroplast proteome.   DOI:  10.1371/journal.pone.0001994 ;  PMID:  18431481
• Analysis of protein complexes in Arabidopsis leaves using size exclusion chromatography and label-free protein correlation profiling.   DOI:  10.1016/j.jprot.2017.06.004 ;  PMID:  28627464

Sequences: