Gene Details:

• Gene ID: AT2G43430
• Gene Symbol: GLX2-1, GLY1, GLYII4
• Gene Name: glyoxalase 2-1, GLYOXALASE II
• Description: glyoxalase 2-1;(source:Araport11)
• TAIR Accession: locus:2058239
• Genome: Araport11_genome_release
• Species: Arabidopsis thaliana

Transcripts:

• AT2G43430.1     AT2G43430.2     AT2G43430.3

Plant Ontology Annotations:

• PO:0000037  — shoot axis apex — ápice del epiblasto (epiblastema) (Spanish, exact), シュート頂、茎頂 (Japanese, exact)
• PO:0008019  — leaf lamina base — base de la lámina de la hoja (Spanish, exact), 葉身基部 (Japanese, exact)
• PO:0009005  — root — raíz (Spanish, exact), radices (exact, plural), radix (exact), 根 (Japanese, exact), aerial root (narrow), climbing root (narrow)
• PO:0009006  — shoot system — sistema de epiblasto (epiblastema) (Spanish, exact), シュート系、苗条系 (Japanese, exact), Poaceae crown (related), shoot (related), thalli (related), thallus (related), tree crown (narrow)
• PO:0009009  — plant embryo — embrión (Spanish, exact), 植物胚 (Japanese, exact), germ (related), embryo (broad)
• PO:0009025  — vascular leaf — foliage leaf (exact), hoja vascular (Spanish, exact), leaf, vascular (exact), vascular leaves (exact, plural), 維管束のある葉, または維管束植物の葉 (Japanese, exact), crozier (related), macrophyll (related), megaphyll (related), ascidia (narrow), ascidium (narrow), fiddlehead (narrow), frond (narrow), needle-like leaf (narrow), pitcher (narrow), pitcher blade (narrow), pitcher-blade (narrow), scale-like leaf (narrow), sterile frond (narrow), trophophyll (narrow)
• PO:0009029  — stamen — estambre (Spanish, exact), 雄蕊 (Japanese, exact), Poaceae stamen (narrow), Zea stamen (narrow)
• PO:0009031  — sepal — sépalo (Spanish, exact), がく片 (Japanese, exact)
• PO:0009046  — flower — flor (Spanish, exact), 花 (Japanese, exact), floret (related), Asteraceae floret (narrow), basal flower (narrow), double flower (narrow), hermaphrodite flower (narrow), monoclinous flower (narrow), perfect flower (narrow)
• PO:0009052  — inflorescence flower pedicel — 小花柄 (Japanese, related), pedicelo (Spanish, broad)
• PO:0020030  — cotyledon — cotiledón (Spanish, exact), seed leaf (exact), 子葉 (Japanese, exact)
• PO:0020038  — petiole — pecíolo (Spanish, exact), 葉柄 (Japanese, exact)
• PO:0020100  — hypocotyl — hipocótile (Spanish, exact), 胚軸 (Japanese, exact)
• PO:0020137  — leaf apex — ápice de la hoja (Spanish, exact), 葉先 (Japanese, exact), leaf lamina apex (narrow), phyllid apex (narrow)
• PO:0025022  — collective leaf structure — estructura colectiva de hoja (Spanish, exact), leaf series (exact), 葉が集まった構造 (Japanese, exact), leaf whorl (narrow), rosette (narrow), cycle (broad), verticil (broad)
• PO:0025281  — pollen — polen (Spanish, exact), pollen grain (exact), 花粉 (Japanese, exact)

Gene Ontology:

• GO:0019243  — involved in — methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione
• GO:0009507  — located in — chloroplast
• GO:0017001  — involved in — antibiotic catabolic process
• GO:0019243  — acts upstream of or within — methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione
• GO:0004416  — enables — hydroxyacylglutathione hydrolase activity
• GO:0008800  — enables — beta-lactamase activity
• GO:0034059  — acts upstream of or within — response to anoxia
• GO:0005737  — located in — cytoplasm
• GO:0009651  — acts upstream of or within — response to salt stress
• GO:0005739  — located in — mitochondrion
• GO:0043200  — acts upstream of or within — response to amino acid
• GO:0008270  — enables — zinc ion binding
• GO:0046872  — enables — metal ion binding

Germplasm Phenotype:

• SALK_059108  — glx2-1 plants were indistinguishable from wild type plants under normal growth conditions. glx2-1 plants are more sensitive to salt stress than wild type plants.

Function-related keywords:

• shoot axis apex ,  leaf lamina base ,  root ,  shoot system ,  plant embryo ,  vascular leaf ,  stamen ,  sepal ,  flower ,  inflorescence flower pedicel ,  cotyledon ,  petiole ,  hypocotyl ,  leaf apex ,  collective leaf structure ,  pollen

Literature:

• Molecular characterization of glyoxalase II from Arabidopsis thaliana.   DOI:  10.1023/a:1005891123344 ;  PMID:  9349270
• Global analysis of Arabidopsis gene expression uncovers a complex array of changes impacting pathogen response and cell cycle during geminivirus infection.   DOI:  10.1104/pp.108.121038 ;  PMID:  18650403
• Arabidopsis thaliana GLX2-1 contains a dinuclear metal binding site, but is not a glyoxalase 2.   DOI:  10.1042/BJ20081151 ;  PMID:  18782082
• Arabidopsis thaliana mitochondrial glyoxalase 2-1 exhibits beta-lactamase activity.   DOI:  10.1021/bi9010539 ;  PMID:  19735113
• Converting GLX2-1 into an active glyoxalase II.   DOI:  10.1021/bi1010865 ;  PMID:  20715794
• Genome-wide analysis of rice and Arabidopsis identifies two glyoxalase genes that are highly expressed in abiotic stresses.   DOI:  10.1007/s10142-010-0203-2 ;  PMID:  21213008
• Arabidopsis thaliana glyoxalase 2-1 is required during abiotic stress but is not essential under normal plant growth.   DOI:  10.1371/journal.pone.0095971 ;  PMID:  24760003
• The metabolite methylglyoxal-mediated gene expression is associated with histone methylglyoxalation.   DOI:  10.1093/nar/gkab014 ;  PMID:  33476385

Sequences: