Gene Details:

• Gene ID: AT2G43410
• Gene Symbol: FPA
• Gene Name:
• Description: RNA binding protein;(source:Araport11)
• TAIR Accession: locus:2058203
• Genome: Araport11_genome_release
• Species: Arabidopsis thaliana

Transcripts:

• AT2G43410.1     AT2G43410.2     AT2G43410.3     AT2G43410.4     AT2G43410.6     AT2G43410.5

Gene Ontology:

• GO:0000785  — colocalizes with — chromatin
• GO:0009793  — acts upstream of or within — embryo development ending in seed dormancy
• GO:0009553  — acts upstream of or within — embryo sac development
• GO:0009911  — acts upstream of or within — positive regulation of flower development
• GO:0003723  — enables — RNA binding
• GO:0006378  — involved in — mRNA polyadenylation
• GO:0031048  — acts upstream of or within — regulatory ncRNA-mediated heterochromatin formation
• GO:0005634  — located in — nucleus
• GO:0000785  — located in — chromatin
• GO:0010228  — acts upstream of or within — vegetative to reproductive phase transition of meristem

Germplasm Phenotype:

• CS109  — late flowering; like fca, but less extreme.
• CS165  — late flowering; vernalization has large effect on flowering time under both long days and short days; flowering occurs about 10 days later than wild type. Rosette leaf number at flowering was more than 2 times higher than in the wild type.
• CS166  — late flowering; vernalization affects flowering time under both long days and short days; flowering occurs about 13 days later than wild type. Rosette leaf number at flowering was more than 2 times higher than in the wild type.
• fca-11/fpa-8  — Late flowering, reduced fertility.
• fpa-6  — Longest delay in flowering (among all fpa mutants). Rosette leaf number at flowering was approximately 5 times higher than in the wild type.

Literature:

• EMF genes interact with late-flowering genes to regulate Arabidopsis shoot development.   DOI:  10.1093/oxfordjournals.pcp.a029381 ;  PMID:  9615462
• Different roles of flowering-time genes in the activation of floral initiation genes in Arabidopsis.   DOI:  10.1105/tpc.9.11.1921 ;  PMID:  9401118
• Interaction of FLC and late-flowering mutations in Arabidopsis thaliana.   DOI:  10.1007/BF02174346 ;  PMID:  8628249
• A genetic and physiological analysis of late flowering mutants in Arabidopsis thaliana.   DOI:  10.1007/BF00264213 ;  PMID:  1896021
• FPA, a gene involved in floral induction in Arabidopsis, encodes a protein containing RNA-recognition motifs.   DOI:  10.1105/tpc.13.6.1427 ;  PMID:  11402170
• PIE1, an ISWI family gene, is required for FLC activation and floral repression in Arabidopsis.   DOI:  10.1105/tpc.012161 ;  PMID:  12837955
• Widespread role for the flowering-time regulators FCA and FPA in RNA-mediated chromatin silencing.   DOI:  10.1126/science.1146565 ;  PMID:  17916737
• Functional redundancy and new roles for genes of the autonomous floral-promotion pathway.   DOI:  10.1104/pp.108.118927 ;  PMID:  18408043
• Regulated RNA processing in the control of Arabidopsis flowering.   DOI:  10.1387/ijdb.051995vq ;  PMID:  16096981
• The spen family protein FPA controls alternative cleavage and polyadenylation of RNA.   DOI:  10.1016/j.devcel.2009.12.009 ;  PMID:  20079695
• Phylogenetic and expression analysis of RNA-binding proteins with triple RNA recognition motifs in plants.   DOI:  10.1007/s10059-011-0001-2 ;  PMID:  21120628
• RNA 3' processing functions of Arabidopsis FCA and FPA limit intergenic transcription.   DOI:  10.1073/pnas.1105334108 ;  PMID:  21536901
• Transcription beyond borders has downstream consequences.   DOI:  10.4161/rna.18668 ;  PMID:  22258223
• Comprehensive analysis of silencing mutants reveals complex regulation of the Arabidopsis methylome.   DOI:  10.1016/j.cell.2012.10.054 ;  PMID:  23313553
• OsRRMh, a Spen-like gene, plays an important role during the vegetative to reproductive transition in rice.   DOI:  10.1111/jipb.12056 ;  PMID:  23621499
• Transcription termination and chimeric RNA formation controlled by Arabidopsis thaliana FPA.   DOI:  10.1371/journal.pgen.1003867 ;  PMID:  24204292
• Crystal Structure of the SPOC Domain of the Arabidopsis Flowering Regulator FPA.   DOI:  10.1371/journal.pone.0160694 ;  PMID:  27513867
• Dehydration stress extends mRNA 3' untranslated regions with noncoding RNA functions in Arabidopsis.   DOI:  10.1101/gr.218669.116 ;  PMID:  28522613
• Expression analysis of the Arabidopsis thaliana AtSpen2 gene, and its relationship with other plant genes encoding Spen proteins.   DOI:  10.1590/1678-4685-GMB-2016-0223 ;  PMID:  28850635
• Research progress on the autonomous flowering time pathway in Arabidopsis.   DOI:  10.1007/s12298-017-0458-3 ;  PMID:  28878488
• Nuclear Speckle RNA Binding Proteins Remodel Alternative Splicing and the Non-coding Arabidopsis Transcriptome to Regulate a Cross-Talk Between Auxin and Immune Responses.   DOI:  10.3389/fpls.2018.01209 ;  PMID:  30186296
• Impact of Alternatively Polyadenylated Isoforms of ETHYLENE RESPONSE FACTOR4 with Activator and Repressor Function on Senescence in Arabidopsis thaliana L.   DOI:  10.3390/genes10020091 ;  PMID:  30696119
• Antagonistic Actions of FPA and IBM2 Regulate Transcript Processing from Genes Containing Heterochromatin.   DOI:  10.1104/pp.18.01106 ;  PMID:  30814131
• Regulation of Flowering Time by the RNA-Binding Proteins AtGRP7 and AtGRP8.   DOI:  10.1093/pcp/pcz124 ;  PMID:  31241165
• Widespread premature transcription termination of Arabidopsis thaliana NLR genes by the spen protein FPA.   DOI:  10.7554/eLife.65537 ;  PMID:  33904405
• The BORDER family of negative transcription elongation factors regulates flowering time in Arabidopsis.   DOI:  10.1016/j.cub.2021.09.074 ;  PMID:  34666004
• The U1 snRNP component RBP45d regulates temperature-responsive flowering in Arabidopsis.   DOI:  10.1093/plcell/koab273 ;  PMID:  34791475
• Landscape of transcription termination in Arabidopsis revealed by single-molecule nascent RNA sequencing.   DOI:  10.1186/s13059-021-02543-4 ;  PMID:  34823554

Sequences: