Gene Details:
- Gene ID: AT2G42790
- Gene Symbol: CSY3
- Gene Name: citrate synthase 3
- Description: citrate synthase 3;(source:Araport11)
- TAIR Accession: locus:2052379
- Genome: Araport11_genome_release
- Species: Arabidopsis thaliana
Transcripts:
Plant Ontology Annotations:
- PO:0000037 — shoot axis apex — ápice del epiblasto (epiblastema) (Spanish, exact), シュート頂、茎頂 (Japanese, exact)
- PO:0008019 — leaf lamina base — base de la lámina de la hoja (Spanish, exact), 葉身基部 (Japanese, exact)
- PO:0009005 — root — raíz (Spanish, exact), radices (exact, plural), radix (exact), 根 (Japanese, exact), aerial root (narrow), climbing root (narrow)
- PO:0009006 — shoot system — sistema de epiblasto (epiblastema) (Spanish, exact), シュート系、苗条系 (Japanese, exact), Poaceae crown (related), shoot (related), thalli (related), thallus (related), tree crown (narrow)
- PO:0009009 — plant embryo — embrión (Spanish, exact), 植物胚 (Japanese, exact), germ (related), embryo (broad)
- PO:0009025 — vascular leaf — foliage leaf (exact), hoja vascular (Spanish, exact), leaf, vascular (exact), vascular leaves (exact, plural), 維管束のある葉, または維管束植物の葉 (Japanese, exact), crozier (related), macrophyll (related), megaphyll (related), ascidia (narrow), ascidium (narrow), fiddlehead (narrow), frond (narrow), needle-like leaf (narrow), pitcher (narrow), pitcher blade (narrow), pitcher-blade (narrow), scale-like leaf (narrow), sterile frond (narrow), trophophyll (narrow)
- PO:0009029 — stamen — estambre (Spanish, exact), 雄蕊 (Japanese, exact), Poaceae stamen (narrow), Zea stamen (narrow)
- PO:0009031 — sepal — sépalo (Spanish, exact), がく片 (Japanese, exact)
- PO:0009046 — flower — flor (Spanish, exact), 花 (Japanese, exact), floret (related), Asteraceae floret (narrow), basal flower (narrow), double flower (narrow), hermaphrodite flower (narrow), monoclinous flower (narrow), perfect flower (narrow)
- PO:0009052 — inflorescence flower pedicel — 小花柄 (Japanese, related), pedicelo (Spanish, broad)
- PO:0020030 — cotyledon — cotiledón (Spanish, exact), seed leaf (exact), 子葉 (Japanese, exact)
- PO:0020038 — petiole — pecíolo (Spanish, exact), 葉柄 (Japanese, exact)
- PO:0020100 — hypocotyl — hipocótile (Spanish, exact), 胚軸 (Japanese, exact)
- PO:0020137 — leaf apex — ápice de la hoja (Spanish, exact), 葉先 (Japanese, exact), leaf lamina apex (narrow), phyllid apex (narrow)
- PO:0025022 — collective leaf structure — estructura colectiva de hoja (Spanish, exact), leaf series (exact), 葉が集まった構造 (Japanese, exact), leaf whorl (narrow), rosette (narrow), cycle (broad), verticil (broad)
- PO:0025281 — pollen — polen (Spanish, exact), pollen grain (exact), 花粉 (Japanese, exact)
- PO:0000084 — plant sperm cell — célula espermática o esperma (Spanish, exact), male gamete (exact), microgamete (exact), 植物精子細胞 (Japanese, exact), sperm nucleus (related), sperm cell (broad)
Gene Ontology:
- GO:0006099 — involved in — tricarboxylic acid cycle
- GO:0004108 — enables — citrate (Si)-synthase activity
- GO:0005777 — located in — peroxisome
- GO:0005759 — is active in — mitochondrial matrix
- GO:0005829 — located in — cytosol
- GO:0006635 — acts upstream of or within — fatty acid beta-oxidation
- GO:0005739 — located in — mitochondrion
- GO:0005975 — involved in — carbohydrate metabolic process
Germplasm Phenotype:
- csy2 csy3 — Dormant seeds. Lack peroxisomal citrate synthase. Cannot mobilize triacyglycerols due to a block in fatty acid beta-oxidation.
Function-related keywords:
- shoot axis apex , leaf lamina base , root , shoot system , plant embryo , vascular leaf , stamen , sepal , flower , inflorescence flower pedicel , cotyledon , petiole , hypocotyl , leaf apex , collective leaf structure , pollen , shoot system , plant sperm cell
Literature:
- Cell cycle-regulated gene expression in Arabidopsis. DOI: 10.1074/jbc.M207570200 ; PMID: 12169696
- Arabidopsis peroxisomal citrate synthase is required for fatty acid respiration and seed germination. DOI: 10.1105/tpc.105.031856 ; PMID: 15923350
- Nine 3-ketoacyl-CoA thiolases (KATs) and acetoacetyl-CoA thiolases (ACATs) encoded by five genes in Arabidopsis thaliana are targeted either to peroxisomes or cytosol but not to mitochondria. DOI: 10.1007/s11103-006-9075-1 ; PMID: 17120136
- Proteome analysis of Arabidopsis leaf peroxisomes reveals novel targeting peptides, metabolic pathways, and defense mechanisms. DOI: 10.1105/tpc.107.050989 ; PMID: 17951448
- Global analysis of Arabidopsis gene expression uncovers a complex array of changes impacting pathogen response and cell cycle during geminivirus infection. DOI: 10.1104/pp.108.121038 ; PMID: 18650403
- The DEG15 serine protease cleaves peroxisomal targeting signal 2-containing proteins in Arabidopsis. DOI: 10.1104/pp.108.125377 ; PMID: 18952862
- Novel proteins, putative membrane transporters, and an integrated metabolic network are revealed by quantitative proteomic analysis of Arabidopsis cell culture peroxisomes. DOI: 10.1104/pp.108.129999 ; PMID: 18931141
- Systems analysis of seed filling in Arabidopsis: using general linear modeling to assess concordance of transcript and protein expression. DOI: 10.1104/pp.109.152413 ; PMID: 20118269
- Proteome analysis of Arabidopsis leaf peroxisomes reveals novel targeting peptides, metabolic pathways, and defense mechanisms. DOI: 10.1105/tpc.107.050989 ; PMID: 17951448
- Analysis of the Arabidopsis cytosolic proteome highlights subcellular partitioning of central plant metabolism. DOI: 10.1021/pr1009433 ; PMID: 21166475
- Analysis of protein complexes in Arabidopsis leaves using size exclusion chromatography and label-free protein correlation profiling. DOI: 10.1016/j.jprot.2017.06.004 ; PMID: 28627464
Sequences:
cDNA Sequence
- >AT2G42790.1
CGAAGAGTAAGAATGGTTTCTAATAATTTCTTCGCTCCCTTTCTTCTTCTTCTCTCCTTCTTTGAATTTTGATTTTGGTTGAATGGAGATATCAGAGAGAGTTCGAGCTCGATTAGCTGTTCTCTCAGGTCATTTATCGGAAGGAAAACAGGATTCTCCAGCGATCGAGCGATGGTGCACGTCGGCGGATACGAGTGTCGCACCGCTTGGATCTTTGAAGGGAACACTGACGATCGTCGACGAACGCACCGGAAAAAATTATAAAGTTCCGGTCTCAGATGATGGTACCGTTAAAGCCGTTGATTTCAAAAAGATAGTGACGGGGAAGGAAGACAAGGGGCTTAAGTTATACGATCCAGGTTACTTGAACACGGCTCCTGTTCGATCTTCGATTTCTTACATCGATGGAGATGAAGGGATCCTTCGTTACCGTGGCTACCCAATTGAGGAAATGGCTGAGAACAGTACTTTTCTGGAGGTGGCTTATCTTCTCATGTATGGGAATCTGCCCTCTGAAAGTCAGCTATCTGATTGGGAGTTTGCAGTTTCTCAGCATTCAGCTGTGCCACAAGGTGTATTAGATATTATACAGTCTATGCCTCATGATGCACACCCAATGGGAGTTCTTGTGAGTGCAATGAGTGCGCTTTCCATCTTTCATCCTGATGCTAATCCTGCTCTTAGGGGCCAGGATATTTACGATTCAAAACAAGTTAGAGATAAACAAATTATCCGCATTATTGGAAAGGCACCAACAATTGCAGCAGCTGCTTATCTGAGGATGGCAGGAAGGCCTCCTGTTCTTCCTTCAGGAAACCTTCCTTATGCAGATAATTTCCTCTATATGCTTGATTCCCTGGGAAATAGATCCTACAAACCTAATCCTCGGCTGGCTCGGGTGTTGGACATCCTCTTCATACTGCATGCAGAGCATGAAATGAACTGCTCCACCGCTGCTGCTCGGCATCTTGCCTCTAGCGGTGTTGATGTCTACACTGCTGTTGCTGGAGCTGTGGGAGCGCTTTATGGTCCACTTCATGGTGGTGCAAACGAGGCTGTGCTTAAGATGTTGTCAGAGATTGGGACTGTTGAAAATATTCCAGAGTTCATTGAGGGTGTGAAGAACAGGAAGAGGAAGATGTCTGGTTTTGGACACCGTGTGTACAAAAACTATGACCCTCGAGCTAAAGTCATCAAGAACCTGGCTGATGAAGTATTTTCCATTGTTGGAAAGGATCCTCTAATTGAGGTTGCTGTTGCACTTGAGAAGGCAGCTCTCTCTGACGATTACTTTGTTAAGAGAAAGCTGTATCCAAATGTTGACTTCTACTCTGGATTAATATACAGGGCAATGGGATTTCCACCGGAGTTCTTCACGGTCTTATTCGCGATTCCTCGCATGGCTGGATACTTGTCACATTGGAAAGAGTCACTGGATGATCCTGACACCAAGATCATGAGACCACAACAGGTGTACACAGGCGTGTGGCTGAGGCATTACACACCAGTGAGAGAGAGAATAGTGACGGATGACTCGAAAGAGTCAGACAAATTGGGTCAAGTCGCGACTTCAAATGCATCAAGAAGACGTTTGGCTGGATCTTCAGTTTAGACGTAGGCCCTTTTAGGGTCCATACTATACATCAAACCACACCGCAAAGAATAAAAGAGATTGGTTTCTCTAGCCTAAAGCTAAGATACTTGATCATACTCGAAACTTAGATTTCTCATTTTGTAGGCACAATATAGACTTGATCTATATTTGCTTCAATCCATCTTCTAAGGGTGTTTGTCCGCCTTGTTTGTCTTCTTATCAGAACGTGTTTATTGTATAAAATGATTTATGGTTATGGATTATTACTCTAATTTCTATATCGAATGCTTCTGCAGAGACGTTTGTTGT
CDS Sequence
- >AT2G42790.1
ATGGAGATATCAGAGAGAGTTCGAGCTCGATTAGCTGTTCTCTCAGGTCATTTATCGGAAGGAAAACAGGATTCTCCAGCGATCGAGCGATGGTGCACGTCGGCGGATACGAGTGTCGCACCGCTTGGATCTTTGAAGGGAACACTGACGATCGTCGACGAACGCACCGGAAAAAATTATAAAGTTCCGGTCTCAGATGATGGTACCGTTAAAGCCGTTGATTTCAAAAAGATAGTGACGGGGAAGGAAGACAAGGGGCTTAAGTTATACGATCCAGGTTACTTGAACACGGCTCCTGTTCGATCTTCGATTTCTTACATCGATGGAGATGAAGGGATCCTTCGTTACCGTGGCTACCCAATTGAGGAAATGGCTGAGAACAGTACTTTTCTGGAGGTGGCTTATCTTCTCATGTATGGGAATCTGCCCTCTGAAAGTCAGCTATCTGATTGGGAGTTTGCAGTTTCTCAGCATTCAGCTGTGCCACAAGGTGTATTAGATATTATACAGTCTATGCCTCATGATGCACACCCAATGGGAGTTCTTGTGAGTGCAATGAGTGCGCTTTCCATCTTTCATCCTGATGCTAATCCTGCTCTTAGGGGCCAGGATATTTACGATTCAAAACAAGTTAGAGATAAACAAATTATCCGCATTATTGGAAAGGCACCAACAATTGCAGCAGCTGCTTATCTGAGGATGGCAGGAAGGCCTCCTGTTCTTCCTTCAGGAAACCTTCCTTATGCAGATAATTTCCTCTATATGCTTGATTCCCTGGGAAATAGATCCTACAAACCTAATCCTCGGCTGGCTCGGGTGTTGGACATCCTCTTCATACTGCATGCAGAGCATGAAATGAACTGCTCCACCGCTGCTGCTCGGCATCTTGCCTCTAGCGGTGTTGATGTCTACACTGCTGTTGCTGGAGCTGTGGGAGCGCTTTATGGTCCACTTCATGGTGGTGCAAACGAGGCTGTGCTTAAGATGTTGTCAGAGATTGGGACTGTTGAAAATATTCCAGAGTTCATTGAGGGTGTGAAGAACAGGAAGAGGAAGATGTCTGGTTTTGGACACCGTGTGTACAAAAACTATGACCCTCGAGCTAAAGTCATCAAGAACCTGGCTGATGAAGTATTTTCCATTGTTGGAAAGGATCCTCTAATTGAGGTTGCTGTTGCACTTGAGAAGGCAGCTCTCTCTGACGATTACTTTGTTAAGAGAAAGCTGTATCCAAATGTTGACTTCTACTCTGGATTAATATACAGGGCAATGGGATTTCCACCGGAGTTCTTCACGGTCTTATTCGCGATTCCTCGCATGGCTGGATACTTGTCACATTGGAAAGAGTCACTGGATGATCCTGACACCAAGATCATGAGACCACAACAGGTGTACACAGGCGTGTGGCTGAGGCATTACACACCAGTGAGAGAGAGAATAGTGACGGATGACTCGAAAGAGTCAGACAAATTGGGTCAAGTCGCGACTTCAAATGCATCAAGAAGACGTTTGGCTGGATCTTCAGTTTAG
Protein Sequence
- >AT2G42790.1
MEISERVRARLAVLSGHLSEGKQDSPAIERWCTSADTSVAPLGSLKGTLTIVDERTGKNYKVPVSDDGTVKAVDFKKIVTGKEDKGLKLYDPGYLNTAPVRSSISYIDGDEGILRYRGYPIEEMAENSTFLEVAYLLMYGNLPSESQLSDWEFAVSQHSAVPQGVLDIIQSMPHDAHPMGVLVSAMSALSIFHPDANPALRGQDIYDSKQVRDKQIIRIIGKAPTIAAAAYLRMAGRPPVLPSGNLPYADNFLYMLDSLGNRSYKPNPRLARVLDILFILHAEHEMNCSTAAARHLASSGVDVYTAVAGAVGALYGPLHGGANEAVLKMLSEIGTVENIPEFIEGVKNRKRKMSGFGHRVYKNYDPRAKVIKNLADEVFSIVGKDPLIEVAVALEKAALSDDYFVKRKLYPNVDFYSGLIYRAMGFPPEFFTVLFAIPRMAGYLSHWKESLDDPDTKIMRPQQVYTGVWLRHYTPVRERIVTDDSKESDKLGQVATSNASRRRLAGSSV