Gene Details:

• Gene ID: AT2G42260
• Gene Symbol: PYM, UVI4
• Gene Name: POLYCHOME, UV-B-INSENSITIVE 4
• Description: uv-b-insensitive 4;(source:Araport11)
• TAIR Accession: locus:2060035
• Genome: Araport11_genome_release
• Species: Arabidopsis thaliana

Transcripts:

• AT2G42260.1     AT2G42260.2

Plant Ontology Annotations:

• PO:0000025  — root tip — punta de la raíz (Spanish, exact), 根端 (Japanese, exact)
• PO:0000036  — leaf vascular system — sistema vascular de la hoja (Spanish, exact), 葉維管系 (Japanese, exact), leaf venation (related)

Gene Ontology:

• GO:0005515  — enables — protein binding
• GO:0010091  — acts upstream of or within — trichome branching
• GO:1900426  — involved in — positive regulation of defense response to bacterium
• GO:1904667  — involved in — negative regulation of ubiquitin protein ligase activity
• GO:0005634  — located in — nucleus
• GO:0042023  — acts upstream of or within — DNA endoreduplication
• GO:0051783  — involved in — regulation of nuclear division
• GO:0009960  — involved in — endosperm development
• GO:0010224  — acts upstream of or within — response to UV-B
• GO:0009561  — involved in — megagametogenesis

Germplasm Phenotype:

• uvi4  — Fresh weight of mutant plants was 2.1 times higher than that of the wild-type plants when grown under supplemental UV-B light. Mutant plants were less sensitive to UV-B light. In addition, the mutant plants have overbranching trichomes on their leaves and stems. Trichomes with more than five branches were often seen on mutant leaves, but were never found on the wild-type leaves.

Function-related keywords:

• root tip ,  leaf vascular system

Literature:

• Trichome cell growth in Arabidopsis thaliana can be derepressed by mutations in at least five genes.   DOI:  10.1093/genetics/152.1.461 ;  PMID:  10224275
• A mutation in the uvi4 gene promotes progression of endo-reduplication and confers increased tolerance towards ultraviolet B light.   DOI:  10.1111/j.1365-313X.2006.02696.x ;  PMID:  16623893
• AGRONOMICS1: a new resource for Arabidopsis transcriptome profiling.   DOI:  10.1104/pp.109.150185 ;  PMID:  20032078
• Targeted interactomics reveals a complex core cell cycle machinery in Arabidopsis thaliana.   DOI:  10.1038/msb.2010.53 ;  PMID:  20706207
• Arabidopsis ULTRAVIOLET-B-INSENSITIVE4 maintains cell division activity by temporal inhibition of the anaphase-promoting complex/cyclosome.   DOI:  10.1105/tpc.111.091793 ;  PMID:  22167059
• GIGAS CELL1, a novel negative regulator of the anaphase-promoting complex/cyclosome, is required for proper mitotic progression and cell fate determination in Arabidopsis.   DOI:  10.1105/tpc.111.092049 ;  PMID:  22167058
• DELLA signaling mediates stress-induced cell differentiation in Arabidopsis leaves through modulation of anaphase-promoting complex/cyclosome activity.   DOI:  10.1104/pp.112.195032 ;  PMID:  22535421
• Roles of GIG1 and UVI4 in genome duplication in Arabidopsis thaliana.   DOI:  10.4161/psb.21133 ;  PMID:  22899078
• Perturbation of cell cycle regulation triggers plant immune response via activation of disease resistance genes.   DOI:  10.1073/pnas.1217024110 ;  PMID:  23345424
• UBIQUITIN-SPECIFIC PROTEASE14 Interacts with ULTRAVIOLET-B INSENSITIVE4 to Regulate Endoreduplication and Cell and Organ Growth in Arabidopsis.   DOI:  10.1105/tpc.16.00007 ;  PMID:  27099260
• Interaction of CPR5 with cell cycle regulators UVI4 and OSD1 in Arabidopsis.   DOI:  10.1371/journal.pone.0100347 ;  PMID:  24945150
• Tissue-Specific Control of the Endocycle by the Anaphase Promoting Complex/Cyclosome Inhibitors UVI4 and DEL1.   DOI:  10.1104/pp.17.00785 ;  PMID:  28698355
• An SNW/SKI-INTERACTING PROTEIN influences endoreduplication and cell growth in Arabidopsis.   DOI:  10.1093/plphys/kiac415 ;  PMID:  36063458

Sequences: