Gene Details:

• Gene ID: AT2G41500
• Gene Symbol: AtPRP4, AtSAP60, EMB2776, LIS, PRP4
• Gene Name: LACHESIS, proline-rich protein 4
• Description: WD-40 repeat family protein / small nuclear ribonucleoprotein Prp4p-like protein;(source:Araport11)
• TAIR Accession: locus:2060560
• Genome: Araport11_genome_release
• Species: Arabidopsis thaliana

Transcripts:

• AT2G41500.1     AT2G41500.2

Plant Ontology Annotations:

• PO:0000037  — shoot axis apex — ápice del epiblasto (epiblastema) (Spanish, exact), シュート頂、茎頂 (Japanese, exact)
• PO:0008019  — leaf lamina base — base de la lámina de la hoja (Spanish, exact), 葉身基部 (Japanese, exact)
• PO:0009005  — root — raíz (Spanish, exact), radices (exact, plural), radix (exact), 根 (Japanese, exact), aerial root (narrow), climbing root (narrow)
• PO:0009006  — shoot system — sistema de epiblasto (epiblastema) (Spanish, exact), シュート系、苗条系 (Japanese, exact), Poaceae crown (related), shoot (related), thalli (related), thallus (related), tree crown (narrow)
• PO:0009009  — plant embryo — embrión (Spanish, exact), 植物胚 (Japanese, exact), germ (related), embryo (broad)
• PO:0009025  — vascular leaf — foliage leaf (exact), hoja vascular (Spanish, exact), leaf, vascular (exact), vascular leaves (exact, plural), 維管束のある葉, または維管束植物の葉 (Japanese, exact), crozier (related), macrophyll (related), megaphyll (related), ascidia (narrow), ascidium (narrow), fiddlehead (narrow), frond (narrow), needle-like leaf (narrow), pitcher (narrow), pitcher blade (narrow), pitcher-blade (narrow), scale-like leaf (narrow), sterile frond (narrow), trophophyll (narrow)
• PO:0009029  — stamen — estambre (Spanish, exact), 雄蕊 (Japanese, exact), Poaceae stamen (narrow), Zea stamen (narrow)
• PO:0009031  — sepal — sépalo (Spanish, exact), がく片 (Japanese, exact)
• PO:0009046  — flower — flor (Spanish, exact), 花 (Japanese, exact), floret (related), Asteraceae floret (narrow), basal flower (narrow), double flower (narrow), hermaphrodite flower (narrow), monoclinous flower (narrow), perfect flower (narrow)
• PO:0009052  — inflorescence flower pedicel — 小花柄 (Japanese, related), pedicelo (Spanish, broad)
• PO:0020030  — cotyledon — cotiledón (Spanish, exact), seed leaf (exact), 子葉 (Japanese, exact)
• PO:0020038  — petiole — pecíolo (Spanish, exact), 葉柄 (Japanese, exact)
• PO:0020100  — hypocotyl — hipocótile (Spanish, exact), 胚軸 (Japanese, exact)
• PO:0020137  — leaf apex — ápice de la hoja (Spanish, exact), 葉先 (Japanese, exact), leaf lamina apex (narrow), phyllid apex (narrow)
• PO:0025022  — collective leaf structure — estructura colectiva de hoja (Spanish, exact), leaf series (exact), 葉が集まった構造 (Japanese, exact), leaf whorl (narrow), rosette (narrow), cycle (broad), verticil (broad)
• PO:0025281  — pollen — polen (Spanish, exact), pollen grain (exact), 花粉 (Japanese, exact)
• PO:0000084  — plant sperm cell — célula espermática o esperma (Spanish, exact), male gamete (exact), microgamete (exact), 植物精子細胞 (Japanese, exact), sperm nucleus (related), sperm cell (broad)
• PO:0020090  — embryo sac central cell — célula central (Spanish, exact), 中央細胞 (Japanese, exact)
• PO:0020094  — plant egg cell — female gamete (exact), megagamete (exact), oocélula (Spanish, exact), 植物卵細胞 (Japanese, exact), egg cell (broad), non-mobile gamete (broad)

Gene Ontology:

• GO:0001709  — acts upstream of or within — cell fate determination
• GO:0080008  — part of — Cul4-RING E3 ubiquitin ligase complex
• GO:0005634  — located in — nucleus
• GO:0016607  — located in — nuclear speck
• GO:0009560  — acts upstream of or within — embryo sac egg cell differentiation
• GO:0017070  — enables — U6 snRNA binding
• GO:0030621  — enables — U4 snRNA binding
• GO:0000398  — acts upstream of or within — mRNA splicing, via spliceosome
• GO:0009553  — acts upstream of or within — embryo sac development
• GO:0046540  — part of — U4/U6 x U5 tri-snRNP complex
• GO:0000398  — involved in — mRNA splicing, via spliceosome
• GO:0005681  — part of — spliceosomal complex
• GO:0007267  — acts upstream of or within — cell-cell signaling

Germplasm Phenotype:

• SALK_070009  — Forms supernumerary egg cells. Homozygous line is lethal.
• lis-1  — Forms supernumerary egg cells. Homozygous line is lethal.

Function-related keywords:

• shoot axis apex ,  leaf lamina base ,  root ,  shoot system ,  plant embryo ,  vascular leaf ,  stamen ,  sepal ,  flower ,  inflorescence flower pedicel ,  cotyledon ,  petiole ,  hypocotyl ,  leaf apex ,  collective leaf structure ,  pollen ,  plant sperm cell ,  embryo sac central cell ,  plant egg cell

Literature:

• A mutation in the AtPRP4 splicing factor gene suppresses seed development in Arabidopsis.   DOI:  10.1055/s-2006-924726 ;  PMID:  17236097
• LACHESIS restricts gametic cell fate in the female gametophyte of Arabidopsis.   DOI:  10.1371/journal.pbio.0050047 ;  PMID:  17326723
• Arabidopsis DDB1-CUL4 ASSOCIATED FACTOR1 forms a nuclear E3 ubiquitin ligase with DDB1 and CUL4 that is involved in multiple plant developmental processes.   DOI:  10.1105/tpc.108.058891 ;  PMID:  18552200
• LACHESIS-dependent egg-cell signaling regulates the development of female gametophytic cells.   DOI:  10.1242/dev.075234 ;  PMID:  22190635
• Molecular foundations of reproductive lethality in Arabidopsis thaliana.   DOI:  10.1371/journal.pone.0028398 ;  PMID:  22164284
• Systematic identification of functional plant modules through the integration of complementary data sources.   DOI:  10.1104/pp.112.196725 ;  PMID:  22589469
• The PRP6-like splicing factor STA1 is involved in RNA-directed DNA methylation by facilitating the production of Pol V-dependent scaffold RNAs.   DOI:  10.1093/nar/gkt639 ;  PMID:  23877244
• Genome-wide identification of EMBRYO-DEFECTIVE (EMB) genes required for growth and development in Arabidopsis.   DOI:  10.1111/nph.16071 ;  PMID:  31334862
• Arabidopsis DDB1-CUL4 ASSOCIATED FACTOR1 forms a nuclear E3 ubiquitin ligase with DDB1 and CUL4 that is involved in multiple plant developmental processes.   DOI:  10.1105/tpc.108.058891 ;  PMID:  18552200
• CLO/GFA1 and ATO are novel regulators of gametic cell fate in plants.   DOI:  10.1111/j.1365-313X.2008.03650.x ;  PMID:  18702672

Sequences: