Information report for AT2G40190
Gene Details
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Functional Descriptions
- lew3 — leaf-wilting; when grown at 21-22C, mutant plants are smaller, have shorter siliques and are less fertile than the wild-type plants. Growth phenotype is partially rescued at higher temperatures (25-26C); collapsed xylem with reduced cellulose content; more sensitive to osmotic stress and ABA.
Functional Keywords
Literature and News
- LEW3, encoding a putative alpha-1,2-mannosyltransferase (ALG11) in N-linked glycoprotein, plays vital roles in cell-wall biosynthesis and the abiotic stress response in Arabidopsis thaliana. DOI: 10.1111/j.1365-313X.2009.04013.x ; PMID: 19732381
- A light-sensitive mutation in Arabidopsis LEW3 reveals the important role of N-glycosylation in root growth and development. DOI: 10.1093/jxb/erx324 ; PMID: 29106622
Gene Resources
- UniProt: W8PUX5
- EMBL: KJ138857
- AlphaFoldDB: W8PUX5
- EnsemblPlants: AT2G40190.1
- Gramene: AT2G40190.1
- KEGG: ath:AT2G40190
- Orthologous matrix: ARLYGWV
- ExpressionAtlas: AT2G40190
- InterPro: IPR001296, IPR031814, IPR038013
- PANTHER: PTHR45919, PTHR45919:SF1
- SUPFAM: SSF53756
- Gene3D: 3.40.50.2000
- SWISS-MODEL: W8PUX5
- Conserved Domain Database: cd03806
Sequences
cDNA Sequence
- >AT2G40190.1
TTGAAACTAAAAATAAAAAGTGTCGGACTTGTAAATTTTCGCTCAGCGATCTGCTTCCAATGGCGATCTACTTCATTCTCTATACACTTCTCACGATCATCTTCGCCGTATCTCTGAGTTTATTTCTTTCCGTGATCAATGCAAGAAAGAGCAGAAAACGTGCGGTAGGATTCTTCCATCCGTACACGAACGACGGTGGCGGCGGCGAGAGAGTGCTCTGGTGCGCCGTTAAAGCCATTCAAGAGGAAAATCCCGATCTTGACTGTGTCATCTTCACCGGAGATCATGACTCTTCTTCTGATAGCTTAGCTCGTCGCGCCGTTGATCGATTCGGTGTTCACCTTCAGTCTCCTCCTAAGGTGATTCATCTAAACAAAAGGAAATGGATTGAAGAGAGTACTTACCCACATTTTACAATGATAGGTCAGAGTCTTGGTTCGGTTTACTTAGCGTGGGAAGCATTACGCATGTTCACTCCTTTGTATTTCCTTGACACTAGTGGATATGCGTTTACATATCCTCTTGCTCGGATCTTTGGTTGCAAAGTTGTTTGCTATACTCATTATCCAACTATTAGTTTGGATATGATTTCTCGTGTTCGTCAGAGGAACTCTATGTATAACAATGATGCTTCCATTGCTAAGAGCAATTGGTTATCTACTTGCAAATTAGTCTATTACAGAGCTTTTAGCTGGATGTATGGGATGGTTGGGTCATGTACTCATTTAGCTATGGTTAACTCTTCGTGGACTAAGTCCCATATCGAAGTGCTTTGGAGAATTCCAGAACGGATTACACGGGTCTACCCGCCCTGTGATACTTCAGGACTTCAGGCGTTTCCTCTTGAACGATCATCTGATCCTCCTAAAATCATATCAGTTGCTCAATTTCGTCCTGAGAAGGCTCATATGCTTCAGCTTGAGGCCTTTTCACTAGCCTTAGAGAAGCTAGATGCAGACGTCCCTAGACCCAAGCTCCAATTTGTGGGAAGTTGTAGAAACAATTCAGATGAAGAACGTCTGCAGAAATTGAAAGACAGAGCAGTGGAACTAAAAGTAGATGGAGACGTGCAATTCTATAAAAATGCCATGTACAGAGAACTAGTGGAACTGTTAGGAAATGCAGTTGCAGGACTGCATGGGATGATAGATGAACACTTTGGTATAAGTGTTGTTGAGTACATGGCTGCTGGTGCAATCCCAATAGCTCACAACTCAGCTGGACCTAAAATGGACATTGTGTTGGAAGAAGACGGACAAAAAACCGGGTTTCTTGCTGAGACTGTGGAGGAATACGCTGAAGCGATCCTTGAGATTGTGAAGATGAATGAAACAGAGAGGCTTAAAATGGCTGAATCTGCTAGAAAACGAGCGGCAAGGTTCTCTGAACAACGGTTTTGTGAGGACTTCAAAACTGCGATTCGACCCATTTTCACAGGTCCTCTTAAATGACAGTTCTTAAACCCTCAAAACCTGCTTACTGCACTAGCTTTTAAACGCACAAGACAAGCTAGGTTATACCTTTTATCCTCTCTTTATAGATTTTTTTTTTTAATTCTGGTTAAAGGTCTGACGTAGACGTTGTAAGAAACAGTTTGGTCAAAAGAAACGAGTAAGATCTTCCTATTTCTAGTTGACTGTTGGGGAAAACTGACACCAACATTTGCTTTCAAACGTTTTCGATTTGTCCGAATGCATTTTATTATGAGAAACTTGGTGCTATTCACTTCAATGAATGGTCGGAATTGGATCTTAACAAGAGAGCAAGATTATGTGAATGTAGCA
CDS Sequence
- >AT2G40190.1
ATGGCGATCTACTTCATTCTCTATACACTTCTCACGATCATCTTCGCCGTATCTCTGAGTTTATTTCTTTCCGTGATCAATGCAAGAAAGAGCAGAAAACGTGCGGTAGGATTCTTCCATCCGTACACGAACGACGGTGGCGGCGGCGAGAGAGTGCTCTGGTGCGCCGTTAAAGCCATTCAAGAGGAAAATCCCGATCTTGACTGTGTCATCTTCACCGGAGATCATGACTCTTCTTCTGATAGCTTAGCTCGTCGCGCCGTTGATCGATTCGGTGTTCACCTTCAGTCTCCTCCTAAGGTGATTCATCTAAACAAAAGGAAATGGATTGAAGAGAGTACTTACCCACATTTTACAATGATAGGTCAGAGTCTTGGTTCGGTTTACTTAGCGTGGGAAGCATTACGCATGTTCACTCCTTTGTATTTCCTTGACACTAGTGGATATGCGTTTACATATCCTCTTGCTCGGATCTTTGGTTGCAAAGTTGTTTGCTATACTCATTATCCAACTATTAGTTTGGATATGATTTCTCGTGTTCGTCAGAGGAACTCTATGTATAACAATGATGCTTCCATTGCTAAGAGCAATTGGTTATCTACTTGCAAATTAGTCTATTACAGAGCTTTTAGCTGGATGTATGGGATGGTTGGGTCATGTACTCATTTAGCTATGGTTAACTCTTCGTGGACTAAGTCCCATATCGAAGTGCTTTGGAGAATTCCAGAACGGATTACACGGGTCTACCCGCCCTGTGATACTTCAGGACTTCAGGCGTTTCCTCTTGAACGATCATCTGATCCTCCTAAAATCATATCAGTTGCTCAATTTCGTCCTGAGAAGGCTCATATGCTTCAGCTTGAGGCCTTTTCACTAGCCTTAGAGAAGCTAGATGCAGACGTCCCTAGACCCAAGCTCCAATTTGTGGGAAGTTGTAGAAACAATTCAGATGAAGAACGTCTGCAGAAATTGAAAGACAGAGCAGTGGAACTAAAAGTAGATGGAGACGTGCAATTCTATAAAAATGCCATGTACAGAGAACTAGTGGAACTGTTAGGAAATGCAGTTGCAGGACTGCATGGGATGATAGATGAACACTTTGGTATAAGTGTTGTTGAGTACATGGCTGCTGGTGCAATCCCAATAGCTCACAACTCAGCTGGACCTAAAATGGACATTGTGTTGGAAGAAGACGGACAAAAAACCGGGTTTCTTGCTGAGACTGTGGAGGAATACGCTGAAGCGATCCTTGAGATTGTGAAGATGAATGAAACAGAGAGGCTTAAAATGGCTGAATCTGCTAGAAAACGAGCGGCAAGGTTCTCTGAACAACGGTTTTGTGAGGACTTCAAAACTGCGATTCGACCCATTTTCACAGGTCCTCTTAAATGA
Protein Sequence
- >AT2G40190.1
MAIYFILYTLLTIIFAVSLSLFLSVINARKSRKRAVGFFHPYTNDGGGGERVLWCAVKAIQEENPDLDCVIFTGDHDSSSDSLARRAVDRFGVHLQSPPKVIHLNKRKWIEESTYPHFTMIGQSLGSVYLAWEALRMFTPLYFLDTSGYAFTYPLARIFGCKVVCYTHYPTISLDMISRVRQRNSMYNNDASIAKSNWLSTCKLVYYRAFSWMYGMVGSCTHLAMVNSSWTKSHIEVLWRIPERITRVYPPCDTSGLQAFPLERSSDPPKIISVAQFRPEKAHMLQLEAFSLALEKLDADVPRPKLQFVGSCRNNSDEERLQKLKDRAVELKVDGDVQFYKNAMYRELVELLGNAVAGLHGMIDEHFGISVVEYMAAGAIPIAHNSAGPKMDIVLEEDGQKTGFLAETVEEYAEAILEIVKMNETERLKMAESARKRAARFSEQRFCEDFKTAIRPIFTGPLK