Gene Details:

• Gene ID: AT2G39810
• Gene Symbol: ESD6, HOS1
• Gene Name: EARLY IN SHORT DAYS 6, HIGH EXPRESSION OF OSMOTICALLY RESPONSIVE GENES 1
• Description: ubiquitin-protein ligase;(source:Araport11)
• TAIR Accession:
• Genome: Araport11_genome_release
• Species: Arabidopsis thaliana

Transcripts:

• AT2G39810.1     AT2G39810.2

Plant Ontology Annotations:

• PO:0000037  — shoot axis apex — ápice del epiblasto (epiblastema) (Spanish, exact), シュート頂、茎頂 (Japanese, exact)
• PO:0008019  — leaf lamina base — base de la lámina de la hoja (Spanish, exact), 葉身基部 (Japanese, exact)
• PO:0009005  — root — raíz (Spanish, exact), radices (exact, plural), radix (exact), 根 (Japanese, exact), aerial root (narrow), climbing root (narrow)
• PO:0009006  — shoot system — sistema de epiblasto (epiblastema) (Spanish, exact), シュート系、苗条系 (Japanese, exact), Poaceae crown (related), shoot (related), thalli (related), thallus (related), tree crown (narrow)
• PO:0009009  — plant embryo — embrión (Spanish, exact), 植物胚 (Japanese, exact), germ (related), embryo (broad)
• PO:0009025  — vascular leaf — foliage leaf (exact), hoja vascular (Spanish, exact), leaf, vascular (exact), vascular leaves (exact, plural), 維管束のある葉, または維管束植物の葉 (Japanese, exact), crozier (related), macrophyll (related), megaphyll (related), ascidia (narrow), ascidium (narrow), fiddlehead (narrow), frond (narrow), needle-like leaf (narrow), pitcher (narrow), pitcher blade (narrow), pitcher-blade (narrow), scale-like leaf (narrow), sterile frond (narrow), trophophyll (narrow)
• PO:0009029  — stamen — estambre (Spanish, exact), 雄蕊 (Japanese, exact), Poaceae stamen (narrow), Zea stamen (narrow)
• PO:0009031  — sepal — sépalo (Spanish, exact), がく片 (Japanese, exact)
• PO:0009046  — flower — flor (Spanish, exact), 花 (Japanese, exact), floret (related), Asteraceae floret (narrow), basal flower (narrow), double flower (narrow), hermaphrodite flower (narrow), monoclinous flower (narrow), perfect flower (narrow)
• PO:0009052  — inflorescence flower pedicel — 小花柄 (Japanese, related), pedicelo (Spanish, broad)
• PO:0020030  — cotyledon — cotiledón (Spanish, exact), seed leaf (exact), 子葉 (Japanese, exact)
• PO:0020038  — petiole — pecíolo (Spanish, exact), 葉柄 (Japanese, exact)
• PO:0020100  — hypocotyl — hipocótile (Spanish, exact), 胚軸 (Japanese, exact)
• PO:0020137  — leaf apex — ápice de la hoja (Spanish, exact), 葉先 (Japanese, exact), leaf lamina apex (narrow), phyllid apex (narrow)
• PO:0025022  — collective leaf structure — estructura colectiva de hoja (Spanish, exact), leaf series (exact), 葉が集まった構造 (Japanese, exact), leaf whorl (narrow), rosette (narrow), cycle (broad), verticil (broad)

Germplasm Phenotype:

• CS24932  — Enhanced gene expression in response to low-temperature conditions; plants are less cold hardy than the wild type; nonetheless, after 2 days of cold acclimation, plants acquired the same degree of freezing tolerance as did the wild type; early flowering and constitutively vernalized; plants are smaller, with fewer leaves, shorter siliques and less vigorous than wild type; kanamycin resistant (30mg/L).
• hos1  — Early flowering, enhanced induction of cold-responsive genes

Function-related keywords:

• shoot axis apex ,  leaf lamina base ,  root ,  shoot system ,  plant embryo ,  vascular leaf ,  stamen ,  sepal ,  flower ,  inflorescence flower pedicel ,  cotyledon ,  petiole ,  hypocotyl ,  leaf apex ,  collective leaf structure

Literature:

• HOS1, a genetic locus involved in cold-responsive gene expression in arabidopsis.   DOI:  10.1105/tpc.10.7.1151 ;  PMID:  9668134
• The Arabidopsis HOS1 gene negatively regulates cold signal transduction and encodes a RING finger protein that displays cold-regulated nucleo–cytoplasmic partitioning.   DOI:  10.1101/gad.866801 ;  PMID:  11297514
• Molecular genetic analysis of cold-regulated gene transcription.   DOI:  10.1098/rstb.2002.1076 ;  PMID:  12171651
• Detecting the undetectable: uncovering duplicated segments in Arabidopsis by comparison with rice.   DOI:  10.1016/s0168-9525(02)02796-8 ;  PMID:  12446138
• Identification of cold-inducible downstream genes of the Arabidopsis DREB1A/CBF3 transcriptional factor using two microarray systems.   DOI:  10.1111/j.1365-313X.2004.02100.x ;  PMID:  15165189
• Regulation of flowering time in Arabidopsis by K homology domain proteins.   DOI:  10.1073/pnas.0404552101 ;  PMID:  15310842
• The negative regulator of plant cold responses, HOS1, is a RING E3 ligase that mediates the ubiquitination and degradation of ICE1.   DOI:  10.1073/pnas.0602874103 ;  PMID:  16702557
• A putative CCAAT-binding transcription factor is a regulator of flowering timing in Arabidopsis.   DOI:  10.1104/pp.107.102079 ;  PMID:  17631525
• Overexpression of AtMYB44 enhances stomatal closure to confer abiotic stress tolerance in transgenic Arabidopsis.   DOI:  10.1104/pp.107.110981 ;  PMID:  18162593
• Identification of ICE2, a gene involved in cold acclimation which determines freezing tolerance in Arabidopsis thaliana.   DOI:  10.1016/j.gene.2008.10.016 ;  PMID:  19026725
• Phenotypic analysis of Arabidopsis mutants: root elongation under salt/hormone-induced stress.   DOI:  10.1101/pdb.prot4968 ;  PMID:  20150051
• Arabidopsis female gametophyte gene expression map reveals similarities between plant and animal gametes.   DOI:  10.1016/j.cub.2010.01.051 ;  PMID:  20226671
• Phenotypic analysis of Arabidopsis mutants: germination rate under salt/hormone-induced stress.   DOI:  10.1101/pdb.prot4969 ;  PMID:  20360355
• ICE1 Ser403 is necessary for protein stabilization and regulation of cold signaling and tolerance.   DOI:  10.1111/j.1365-313X.2011.04589.x ;  PMID:  21447070
• The Arabidopsis E3 ubiquitin ligase HOS1 negatively regulates CONSTANS abundance in the photoperiodic control of flowering.   DOI:  10.1105/tpc.110.081885 ;  PMID:  22408073
• Alternative splicing and expression analysis of High expression of osmotically responsive genes1 (HOS1) in Arabidopsis.   DOI:  10.5483/bmbrep.2012.45.9.092 ;  PMID:  23010172
• The E3 ubiquitin ligase HOS1 regulates low ambient temperature-responsive flowering in Arabidopsis thaliana.   DOI:  10.1093/pcp/pcs123 ;  PMID:  22960247
• The E3 ubiquitin ligase HOS1 regulates Arabidopsis flowering by mediating CONSTANS degradation under cold stress.   DOI:  10.1074/jbc.M112.394338 ;  PMID:  23135282
• Rapid phosphatidic acid accumulation in response to low temperature stress in Arabidopsis is generated through diacylglycerol kinase.   DOI:  10.3389/fpls.2013.00001 ;  PMID:  23346092
• The cold signaling attenuator HIGH EXPRESSION OF OSMOTICALLY RESPONSIVE GENE1 activates FLOWERING LOCUS C transcription via chromatin remodeling under short-term cold stress in Arabidopsis.   DOI:  10.1105/tpc.113.118364 ;  PMID:  24220632
• HIGH EXPRESSION OF OSMOTICALLY RESPONSIVE GENES1 is required for circadian periodicity through the promotion of nucleo-cytoplasmic mRNA export in Arabidopsis.   DOI:  10.1105/tpc.113.114959 ;  PMID:  24254125
• HOS1-mediated activation of FLC via chromatin remodeling under cold stress.   DOI:  10.4161/psb.27342 ;  PMID:  24390058
• Controlled turnover of CONSTANS protein by the HOS1 E3 ligase regulates floral transition at low temperatures.   DOI:  10.4161/psb.23780 ;  PMID:  23425850
• HOS1 regulates Argonaute1 by promoting transcription of the microRNA gene MIR168b in Arabidopsis.   DOI:  10.1111/tpj.12772 ;  PMID:  25619693
• OST1 kinase modulates freezing tolerance by enhancing ICE1 stability in Arabidopsis.   DOI:  10.1016/j.devcel.2014.12.023 ;  PMID:  25669882
• The E3 ubiquitin ligase HOS1 is involved in ethylene regulation of leaf expansion in Arabidopsis.   DOI:  10.1080/15592324.2014.1003755 ;  PMID:  25848954
• The unified ICE-CBF pathway provides a transcriptional feedback control of freezing tolerance during cold acclimation in Arabidopsis.   DOI:  10.1007/s11103-015-0365-3 ;  PMID:  26311645
• Endogenous Arabidopsis messenger RNAs transported to distant tissues.   DOI:  10.1038/nplants.2015.25 ;  PMID:  27247031
• Red Light-Mediated Degradation of CONSTANS by the E3 Ubiquitin Ligase HOS1 Regulates Photoperiodic Flowering in Arabidopsis.   DOI:  10.1105/tpc.15.00529 ;  PMID:  26373454
• Delayed germination of Arabidopsis seeds under chilling stress by overexpressing an abiotic stress inducible GhTPS11.   DOI:  10.1016/j.gene.2015.08.056 ;  PMID:  26325072
• Overexpression of an Orchid (Dendrobium nobile) SOC1/TM3-Like Ortholog, DnAGL19, in Arabidopsis Regulates HOS1-FT Expression.   DOI:  10.3389/fpls.2016.00099 ;  PMID:  26904066
• Exploring the pleiotropy of hos1.   DOI:  10.1093/jxb/erv022 ;  PMID:  25697795
• HOS1 Facilitates the Phytochrome B-Mediated Inhibition of PIF4 Function during Hypocotyl Growth in Arabidopsis.   DOI:  10.1016/j.molp.2016.11.009 ;  PMID:  27890635
• HOS1 acts as a key modulator of hypocotyl photomorphogenesis.   DOI:  10.1080/15592324.2017.1315497 ;  PMID:  28426369
• An Arabidopsis Nucleoporin NUP85 modulates plant responses to ABA and salt stress.   DOI:  10.1371/journal.pgen.1007124 ;  PMID:  29232718
• BRASSINOSTEROID-INSENSITIVE2 Negatively Regulates the Stability of Transcription Factor ICE1 in Response to Cold Stress in Arabidopsis.   DOI:  10.1105/tpc.19.00058 ;  PMID:  31409630
• Nup96 and HOS1 Are Mutually Stabilized and Gate CONSTANS Protein Level, Conferring Long-Day Photoperiodic Flowering Regulation in Arabidopsis.   DOI:  10.1105/tpc.19.00661 ;  PMID:  31826964
• Nuclear pore complex components have temperature-influenced roles in plant growth and immunity.   DOI:  10.1111/pce.13741 ;  PMID:  32022936
• Over 100 Million Years of Enzyme Evolution Underpinning the Production of Morphine in the Papaveraceae Family of Flowering Plants.   DOI:  10.1016/j.xplc.2020.100029 ;  PMID:  32685922
• Nucleoporin 160 Regulates Flowering through Anchoring HOS1 for Destabilizing CO in Arabidopsis.   DOI:  10.1016/j.xplc.2020.100033 ;  PMID:  33367234
• CRISPR/Cas9-Mediated Knockout of HOS1 Reveals Its Role in the Regulation of Secondary Metabolism in Arabidopsis thaliana.   DOI:  10.3390/plants10010104 ;  PMID:  33419060
• HISTONE DEACETYLASE 9 transduces heat signal in plant cells.   DOI:  10.1073/pnas.2206846119 ;  PMID:  36322735
• Suppression of the HOS1 Gene Affects the Level of ROS Depending on Light and Cold.   DOI:  10.3390/life13020524 ;  PMID:  36836880
• HOS1 promotes plant tolerance to low-energy stress via the SnRK1 protein kinase.   DOI:  10.1111/tpj.16250 ;  PMID:  37077033
• Responsiveness to long days for flowering is reduced in Arabidopsis by yearly variation in growing season temperatures.   DOI:  10.1111/pce.14632 ;  PMID:  37249162
• Genetic analysis of osmotic and cold stress signal transduction in Arabidopsis: interactions and convergence of abscisic acid-dependent and abscisic acid-independent pathways.   DOI:  10.1105/tpc.9.11.1935 ;  PMID:  9401119
• Repertoire of plant RING E3 ubiquitin ligases revisited: New groups counting gene families and single genes.   DOI:  10.1371/journal.pone.0203442 ;  PMID:  30169501

Sequences: