Gene Details:

• Gene ID: AT2G38280
• Gene Symbol: FAC1
• Gene Name: EMBRYONIC FACTOR1
• Description: AMP deaminase, putative / myoadenylate deaminase;(source:Araport11)
• TAIR Accession: locus:2042902
• Genome: Araport11_genome_release
• Species: Arabidopsis thaliana

Transcripts:

• AT2G38280.1     AT2G38280.2

Plant Ontology Annotations:

• PO:0000037  — shoot axis apex — ápice del epiblasto (epiblastema) (Spanish, exact), シュート頂、茎頂 (Japanese, exact)
• PO:0008019  — leaf lamina base — base de la lámina de la hoja (Spanish, exact), 葉身基部 (Japanese, exact)
• PO:0009005  — root — raíz (Spanish, exact), radices (exact, plural), radix (exact), 根 (Japanese, exact), aerial root (narrow), climbing root (narrow)
• PO:0009006  — shoot system — sistema de epiblasto (epiblastema) (Spanish, exact), シュート系、苗条系 (Japanese, exact), Poaceae crown (related), shoot (related), thalli (related), thallus (related), tree crown (narrow)
• PO:0009009  — plant embryo — embrión (Spanish, exact), 植物胚 (Japanese, exact), germ (related), embryo (broad)
• PO:0009025  — vascular leaf — foliage leaf (exact), hoja vascular (Spanish, exact), leaf, vascular (exact), vascular leaves (exact, plural), 維管束のある葉, または維管束植物の葉 (Japanese, exact), crozier (related), macrophyll (related), megaphyll (related), ascidia (narrow), ascidium (narrow), fiddlehead (narrow), frond (narrow), needle-like leaf (narrow), pitcher (narrow), pitcher blade (narrow), pitcher-blade (narrow), scale-like leaf (narrow), sterile frond (narrow), trophophyll (narrow)
• PO:0009029  — stamen — estambre (Spanish, exact), 雄蕊 (Japanese, exact), Poaceae stamen (narrow), Zea stamen (narrow)
• PO:0009031  — sepal — sépalo (Spanish, exact), がく片 (Japanese, exact)
• PO:0009046  — flower — flor (Spanish, exact), 花 (Japanese, exact), floret (related), Asteraceae floret (narrow), basal flower (narrow), double flower (narrow), hermaphrodite flower (narrow), monoclinous flower (narrow), perfect flower (narrow)
• PO:0009052  — inflorescence flower pedicel — 小花柄 (Japanese, related), pedicelo (Spanish, broad)
• PO:0020030  — cotyledon — cotiledón (Spanish, exact), seed leaf (exact), 子葉 (Japanese, exact)
• PO:0020038  — petiole — pecíolo (Spanish, exact), 葉柄 (Japanese, exact)
• PO:0020100  — hypocotyl — hipocótile (Spanish, exact), 胚軸 (Japanese, exact)
• PO:0020137  — leaf apex — ápice de la hoja (Spanish, exact), 葉先 (Japanese, exact), leaf lamina apex (narrow), phyllid apex (narrow)
• PO:0025022  — collective leaf structure — estructura colectiva de hoja (Spanish, exact), leaf series (exact), 葉が集まった構造 (Japanese, exact), leaf whorl (narrow), rosette (narrow), cycle (broad), verticil (broad)
• PO:0025281  — pollen — polen (Spanish, exact), pollen grain (exact), 花粉 (Japanese, exact)
• PO:0000001  — plant embryo proper — embrióforo (Spanish, exact), 胚本体 (Japanese, exact)
• PO:0025074  — embryo sac — saco embrionario (Spanish, exact), 胚嚢 (Japanese, exact)

Gene Ontology:

• GO:0043231  — located in — intracellular membrane-bounded organelle
• GO:0043424  — enables — protein histidine kinase binding
• GO:0005515  — enables — protein binding
• GO:0003876  — enables — AMP deaminase activity
• GO:0006188  — involved in — IMP biosynthetic process
• GO:0005783  — located in — endoplasmic reticulum
• GO:0005741  — located in — mitochondrial outer membrane
• GO:0009793  — acts upstream of or within — embryo development ending in seed dormancy
• GO:0032264  — involved in — IMP salvage
• GO:0009507  — located in — chloroplast
• GO:0046033  — involved in — AMP metabolic process
• GO:0005829  — is active in — cytosol

Germplasm Phenotype:

• SALK_055006  — Embryonic lethal in homozygotes.

Function-related keywords:

• shoot axis apex ,  leaf lamina base ,  root ,  shoot system ,  plant embryo ,  vascular leaf ,  stamen ,  sepal ,  flower ,  inflorescence flower pedicel ,  cotyledon ,  petiole ,  hypocotyl ,  leaf apex ,  collective leaf structure ,  pollen ,  plant embryo proper ,  root ,  shoot system ,  embryo sac ,  pollen

Literature:

• EMBRYONIC FACTOR 1 encodes an AMP deaminase and is essential for the zygote to embryo transition in Arabidopsis.   DOI:  10.1111/j.1365-313X.2005.02411.x ;  PMID:  15918887
• Membrane association, mechanism of action, and structure of Arabidopsis embryonic factor 1 (FAC1).   DOI:  10.1074/jbc.M513009200 ;  PMID:  16543243
• Crystallization and preliminary X-ray crystallographic analysis of adenosine 5'-monophosphate deaminase (AMPD) from Arabidopsis thaliana in complex with coformycin 5'-phosphate.   DOI:  10.1107/S1744309105019792 ;  PMID:  16511144
• Arabidopsis DCP2, DCP1, and VARICOSE form a decapping complex required for postembryonic development.   DOI:  10.1105/tpc.106.047605 ;  PMID:  17158604
• Arabidopsis GLAUCE promotes fertilization-independent endosperm development and expression of paternally inherited alleles.   DOI:  10.1242/dev.007310 ;  PMID:  17965055
• Site-specific phosphorylation profiling of Arabidopsis proteins by mass spectrometry and peptide chip analysis.   DOI:  10.1021/pr8000173 ;  PMID:  18433157
• In planta changes in protein phosphorylation induced by the plant hormone abscisic acid.   DOI:  10.1073/pnas.1007879107 ;  PMID:  20733066
• Species specific amino acid sequence-protein local structure relationships: An analysis in the light of a structural alphabet.   DOI:  10.1016/j.jtbi.2011.01.047 ;  PMID:  21333657
• Multiple lines of evidence localize signaling, morphology, and lipid biosynthesis machinery to the mitochondrial outer membrane of Arabidopsis.   DOI:  10.1104/pp.111.183160 ;  PMID:  21896887
• Genome-wide identification of EMBRYO-DEFECTIVE (EMB) genes required for growth and development in Arabidopsis.   DOI:  10.1111/nph.16071 ;  PMID:  31334862
• Adenosine monophosphate deaminase modulates BIN2 activity through hydrogen peroxide-induced oligomerization.   DOI:  10.1093/plcell/koac203 ;  PMID:  35876813
• Adenine nucleotide pool perturbation is a metabolic trigger for AMP deaminase inhibitor-based herbicide toxicity.   DOI:  10.1104/pp.107.096487 ;  PMID:  17307896
• Site-specific phosphorylation profiling of Arabidopsis proteins by mass spectrometry and peptide chip analysis.   DOI:  10.1021/pr8000173 ;  PMID:  18433157
• Site-specific phosphorylation profiling of Arabidopsis proteins by mass spectrometry and peptide chip analysis.   DOI:  10.1021/pr8000173 ;  PMID:  18433157

Sequences: