Gene Details:

• Gene ID: AT2G32700
• Gene Symbol: LUH, MUM1
• Gene Name: LEUNIG_homolog, MUCILAGE-MODIFIED 1
• Description: LEUNIG-like protein;(source:Araport11)
• TAIR Accession: locus:2046437
• Genome: Araport11_genome_release
• Species: Arabidopsis thaliana

Transcripts:

• AT2G32700.1     AT2G32700.3     AT2G32700.2     AT2G32700.5     AT2G32700.4     AT2G32700.6     AT2G32700.7

Plant Ontology Annotations:

• PO:0000037  — shoot axis apex — ápice del epiblasto (epiblastema) (Spanish, exact), シュート頂、茎頂 (Japanese, exact)
• PO:0008019  — leaf lamina base — base de la lámina de la hoja (Spanish, exact), 葉身基部 (Japanese, exact)
• PO:0009005  — root — raíz (Spanish, exact), radices (exact, plural), radix (exact), 根 (Japanese, exact), aerial root (narrow), climbing root (narrow)
• PO:0009006  — shoot system — sistema de epiblasto (epiblastema) (Spanish, exact), シュート系、苗条系 (Japanese, exact), Poaceae crown (related), shoot (related), thalli (related), thallus (related), tree crown (narrow)
• PO:0009009  — plant embryo — embrión (Spanish, exact), 植物胚 (Japanese, exact), germ (related), embryo (broad)
• PO:0009025  — vascular leaf — foliage leaf (exact), hoja vascular (Spanish, exact), leaf, vascular (exact), vascular leaves (exact, plural), 維管束のある葉, または維管束植物の葉 (Japanese, exact), crozier (related), macrophyll (related), megaphyll (related), ascidia (narrow), ascidium (narrow), fiddlehead (narrow), frond (narrow), needle-like leaf (narrow), pitcher (narrow), pitcher blade (narrow), pitcher-blade (narrow), scale-like leaf (narrow), sterile frond (narrow), trophophyll (narrow)
• PO:0009029  — stamen — estambre (Spanish, exact), 雄蕊 (Japanese, exact), Poaceae stamen (narrow), Zea stamen (narrow)
• PO:0009031  — sepal — sépalo (Spanish, exact), がく片 (Japanese, exact)
• PO:0009046  — flower — flor (Spanish, exact), 花 (Japanese, exact), floret (related), Asteraceae floret (narrow), basal flower (narrow), double flower (narrow), hermaphrodite flower (narrow), monoclinous flower (narrow), perfect flower (narrow)
• PO:0009052  — inflorescence flower pedicel — 小花柄 (Japanese, related), pedicelo (Spanish, broad)
• PO:0020030  — cotyledon — cotiledón (Spanish, exact), seed leaf (exact), 子葉 (Japanese, exact)
• PO:0020038  — petiole — pecíolo (Spanish, exact), 葉柄 (Japanese, exact)
• PO:0020100  — hypocotyl — hipocótile (Spanish, exact), 胚軸 (Japanese, exact)
• PO:0020137  — leaf apex — ápice de la hoja (Spanish, exact), 葉先 (Japanese, exact), leaf lamina apex (narrow), phyllid apex (narrow)
• PO:0025022  — collective leaf structure — estructura colectiva de hoja (Spanish, exact), leaf series (exact), 葉が集まった構造 (Japanese, exact), leaf whorl (narrow), rosette (narrow), cycle (broad), verticil (broad)
• PO:0025281  — pollen — polen (Spanish, exact), pollen grain (exact), 花粉 (Japanese, exact)

Gene Ontology:

• GO:0045892  — acts upstream of or within — negative regulation of DNA-templated transcription
• GO:0009909  — involved in — regulation of flower development
• GO:0009944  — involved in — polarity specification of adaxial/abaxial axis
• GO:0071217  — involved in — cellular response to external biotic stimulus
• GO:0006974  — involved in — DNA damage response
• GO:1902066  — acts upstream of or within — regulation of cell wall pectin metabolic process
• GO:2000024  — involved in — regulation of leaf development
• GO:0010044  — acts upstream of or within — response to aluminum ion
• GO:0006355  — acts upstream of or within — regulation of DNA-templated transcription
• GO:0009793  — acts upstream of or within — embryo development ending in seed dormancy
• GO:0045893  — involved in — positive regulation of DNA-templated transcription
• GO:0048359  — involved in — mucilage metabolic process involved in seed coat development
• GO:0005515  — enables — protein binding
• GO:0009620  — involved in — response to fungus
• GO:0005634  — located in — nucleus
• GO:0009733  — involved in — response to auxin
• GO:0006979  — involved in — response to oxidative stress
• GO:0048358  — acts upstream of or within — mucilage pectin biosynthetic process
• GO:0009617  — involved in — response to bacterium
• GO:0047484  — involved in — regulation of response to osmotic stress
• GO:0001666  — involved in — response to hypoxia
• GO:0009414  — involved in — response to water deprivation
• GO:0010272  — involved in — response to silver ion
• GO:0080001  — involved in — mucilage extrusion from seed coat
• GO:0045995  — involved in — regulation of embryonic development
• GO:1901001  — involved in — negative regulation of response to salt stress
• GO:0046898  — involved in — response to cycloheximide
• GO:0009908  — acts upstream of or within — flower development
• GO:0009827  — involved in — plant-type cell wall modification
• GO:0010192  — involved in — mucilage biosynthetic process
• GO:1902183  — involved in — regulation of shoot apical meristem development
• GO:0045892  — involved in — negative regulation of DNA-templated transcription
• GO:0003714  — enables — transcription corepressor activity
• GO:0010393  — involved in — galacturonan metabolic process
• GO:1902074  — involved in — response to salt
• GO:0009624  — involved in — response to nematode
• GO:0009611  — involved in — response to wounding
• GO:0003713  — enables — transcription coactivator activity
• GO:0010073  — involved in — meristem maintenance
• GO:0009827  — acts upstream of or within — plant-type cell wall modification

Germplasm Phenotype:

• CS3903  — Defective in seed coat mucilage secretory cells; seed coats do not release mucilage when placed in an aqueous environment.
• SALK_107245C  — Significantly less root growth inhibition when grown in the presence of Al compared to WT. Reduced Al accumulation in the cell wall rather than the symplast in comparison with wild type roots. Lower content of unmethylated pectin in the root cell walls.
• lug-16/luh-1  — Double homozygote are difficult to recover and may die very early in embryogenesis. Plants that do form are reduced in size with mature plants as small as single leaves. The inflorescence bears few flowers consisting of only carpels.
• luh-1  — Reduced germination (80% of normal), slow initial growth, short roots.
• luh-1/lug-16  — Reduced fertility- siliques do not elongate. Flower phenotype resembles the lug-16 single mutant with narrow sepals and petals. A percentage are also embryo lethal.
• luh-1/lug-3  — Mutant flowers have carpelloid sepals and sepal like organs topped with horns. No petals and stames are absent or fused to first whorl organs. Sterile.
• luh-1/seu-1  — Resembles seu-1 single mutant with reduced stamen number.

Function-related keywords:

• shoot axis apex ,  leaf lamina base ,  root ,  shoot system ,  plant embryo ,  vascular leaf ,  stamen ,  sepal ,  flower ,  inflorescence flower pedicel ,  cotyledon ,  petiole ,  hypocotyl ,  leaf apex ,  collective leaf structure ,  pollen

Literature:

• Isolation and characterization of mutants defective in seed coat mucilage secretory cell development in Arabidopsis.   DOI:  6897 ;  PMID:  11706181
• Improving the Arabidopsis genome annotation using maximal transcript alignment assemblies.   DOI:  10.1093/nar/gkg770 ;  PMID:  14500829
• The rotunda2 mutants identify a role for the LEUNIG gene in vegetative leaf morphogenesis.   DOI:  10.1093/jxb/erh165 ;  PMID:  15208345
• Novel and stress-regulated microRNAs and other small RNAs from Arabidopsis.   DOI:  10.1105/tpc.104.022830 ;  PMID:  15258262
• Molecular and genetic interactions between STYLOSA and GRAMINIFOLIA in the control of Antirrhinum vegetative and reproductive development.   DOI:  10.1242/dev.01205 ;  PMID:  15229173
• LEUNIG_HOMOLOG and LEUNIG perform partially redundant functions during Arabidopsis embryo and floral development.   DOI:  10.1104/pp.108.115923 ;  PMID:  18390806
• Global analysis of Arabidopsis gene expression uncovers a complex array of changes impacting pathogen response and cell cycle during geminivirus infection.   DOI:  10.1104/pp.108.121038 ;  PMID:  18650403
• YABBYs and the transcriptional corepressors LEUNIG and LEUNIG_HOMOLOG maintain leaf polarity and meristem activity in Arabidopsis.   DOI:  10.1105/tpc.109.070458 ;  PMID:  19837869
• Bimolecular fluorescence complementation (BiFC) assay for protein-protein interaction in onion cells using the helios gene gun.   DOI:  10.3791/1963 ;  PMID:  20567209
• The transcriptional regulator LEUNIG_HOMOLOG regulates mucilage release from the Arabidopsis testa.   DOI:  10.1104/pp.111.172692 ;  PMID:  21402796
• LEUNIG_HOMOLOG and LEUNIG regulate seed mucilage extrusion in Arabidopsis.   DOI:  10.1111/j.1744-7909.2011.01036.x ;  PMID:  21362134
• The Arabidopsis transcription factor LUH/MUM1 is required for extrusion of seed coat mucilage.   DOI:  10.1104/pp.111.172023 ;  PMID:  21518777
• The TOPLESS interactome: a framework for gene repression in Arabidopsis.   DOI:  10.1104/pp.111.186999 ;  PMID:  22065421
• Involvement of co-repressor LUH and the adapter proteins SLK1 and SLK2 in the regulation of abiotic stress response genes in Arabidopsis.   DOI:  10.1186/1471-2229-14-54 ;  PMID:  24564815
• Expression of PRX36, PMEI6 and SBT1.7 is controlled by complex transcription factor regulatory networks for proper seed coat mucilage extrusion.   DOI:  10.4161/15592324.2014.977734 ;  PMID:  25531128
• Starting to gel: how Arabidopsis seed coat epidermal cells produce specialized secondary cell walls.   DOI:  10.3390/ijms16023452 ;  PMID:  25658798
• The Transcriptional Coregulator LEUNIG_HOMOLOG Inhibits Light-Dependent Seed Germination in Arabidopsis.   DOI:  10.1105/tpc.15.00444 ;  PMID:  26276832
• The Developmental Regulator SEEDSTICK Controls Structural and Mechanical Properties of the Arabidopsis Seed Coat.   DOI:  10.1105/tpc.16.00454 ;  PMID:  27624758
• LEUNIG_HOMOLOG transcriptional co-repressor mediates aluminium sensitivity through PECTIN METHYLESTERASE46-modulated root cell wall pectin methylesterification in Arabidopsis.   DOI:  10.1111/tpj.13506 ;  PMID:  28181322
• Insights into the role of transcription factors controlling mucilage production in the Arabidopsis seed coat.   DOI:  10.1016/j.plantsci.2018.04.021 ;  PMID:  29807590
• MUD1, a RING-v E3 ubiquitin ligase, has an important role in the regulation of pectin methylesterification in Arabidopsis seed coat mucilage.   DOI:  10.1016/j.plaphy.2021.10.001 ;  PMID:  34649026
• MYB52 Negatively Regulates Pectin Demethylesterification in Seed Coat Mucilage.   DOI:  10.1104/pp.17.01771 ;  PMID:  29440562
• The Genetic Control of SEEDSTICK and LEUNIG-HOMOLOG in Seed and Fruit Development: New Insights into Cell Wall Control.   DOI:  10.3390/plants11223146 ;  PMID:  36432874
• LEUNIG_HOMOLOG and LEUNIG perform partially redundant functions during Arabidopsis embryo and floral development.   DOI:  10.1104/pp.108.115923 ;  PMID:  18390806
• LEUNIG_HOMOLOG and LEUNIG perform partially redundant functions during Arabidopsis embryo and floral development.   DOI:  10.1104/pp.108.115923 ;  PMID:  18390806
• LEUNIG_HOMOLOG and LEUNIG perform partially redundant functions during Arabidopsis embryo and floral development.   DOI:  10.1104/pp.108.115923 ;  PMID:  18390806
• LEUNIG_HOMOLOG and LEUNIG perform partially redundant functions during Arabidopsis embryo and floral development.   DOI:  10.1104/pp.108.115923 ;  PMID:  18390806
• LEUNIG_HOMOLOG and LEUNIG perform partially redundant functions during Arabidopsis embryo and floral development.   DOI:  10.1104/pp.108.115923 ;  PMID:  18390806

Sequences: