Gene Details:
- Gene ID: AT2G32640
- Gene Symbol: LCYB
- Gene Name: lycopene beta-cylcase
- Description: Lycopene beta/epsilon cyclase protein;(source:Araport11)
- TAIR Accession: locus:2046422
- Genome: Araport11_genome_release
- Species: Arabidopsis thaliana
Transcripts:
Plant Ontology Annotations:
- PO:0000037 — shoot axis apex — ápice del epiblasto (epiblastema) (Spanish, exact), シュート頂、茎頂 (Japanese, exact)
- PO:0008019 — leaf lamina base — base de la lámina de la hoja (Spanish, exact), 葉身基部 (Japanese, exact)
- PO:0009006 — shoot system — sistema de epiblasto (epiblastema) (Spanish, exact), シュート系、苗条系 (Japanese, exact), Poaceae crown (related), shoot (related), thalli (related), thallus (related), tree crown (narrow)
- PO:0009009 — plant embryo — embrión (Spanish, exact), 植物胚 (Japanese, exact), germ (related), embryo (broad)
- PO:0009025 — vascular leaf — foliage leaf (exact), hoja vascular (Spanish, exact), leaf, vascular (exact), vascular leaves (exact, plural), 維管束のある葉, または維管束植物の葉 (Japanese, exact), crozier (related), macrophyll (related), megaphyll (related), ascidia (narrow), ascidium (narrow), fiddlehead (narrow), frond (narrow), needle-like leaf (narrow), pitcher (narrow), pitcher blade (narrow), pitcher-blade (narrow), scale-like leaf (narrow), sterile frond (narrow), trophophyll (narrow)
- PO:0009029 — stamen — estambre (Spanish, exact), 雄蕊 (Japanese, exact), Poaceae stamen (narrow), Zea stamen (narrow)
- PO:0009031 — sepal — sépalo (Spanish, exact), がく片 (Japanese, exact)
- PO:0009046 — flower — flor (Spanish, exact), 花 (Japanese, exact), floret (related), Asteraceae floret (narrow), basal flower (narrow), double flower (narrow), hermaphrodite flower (narrow), monoclinous flower (narrow), perfect flower (narrow)
- PO:0009052 — inflorescence flower pedicel — 小花柄 (Japanese, related), pedicelo (Spanish, broad)
- PO:0020030 — cotyledon — cotiledón (Spanish, exact), seed leaf (exact), 子葉 (Japanese, exact)
- PO:0020038 — petiole — pecíolo (Spanish, exact), 葉柄 (Japanese, exact)
- PO:0020100 — hypocotyl — hipocótile (Spanish, exact), 胚軸 (Japanese, exact)
- PO:0020137 — leaf apex — ápice de la hoja (Spanish, exact), 葉先 (Japanese, exact), leaf lamina apex (narrow), phyllid apex (narrow)
- PO:0025022 — collective leaf structure — estructura colectiva de hoja (Spanish, exact), leaf series (exact), 葉が集まった構造 (Japanese, exact), leaf whorl (narrow), rosette (narrow), cycle (broad), verticil (broad)
Gene Ontology:
- GO:0009507 — located in — chloroplast
- GO:0006721 — acts upstream of or within — terpenoid metabolic process
- GO:0009416 — acts upstream of or within — response to light stimulus
Function-related keywords:
- shoot axis apex , leaf lamina base , shoot system , plant embryo , vascular leaf , stamen , sepal , flower , inflorescence flower pedicel , cotyledon , petiole , hypocotyl , leaf apex , collective leaf structure
Literature:
- The FHY3 and FAR1 genes encode transposase-related proteins involved in regulation of gene expression by the phytochrome A-signaling pathway. DOI: 10.1046/j.1365-313x.2003.01741.x ; PMID: 12753585
- Inactivation of the chloroplast ATP synthase gamma subunit results in high non-photochemical fluorescence quenching and altered nuclear gene expression in Arabidopsis thaliana. DOI: 10.1074/jbc.M308435200 ; PMID: 14576160
- Functional differentiation of peroxisomes revealed by expression profiles of peroxisomal genes in Arabidopsis thaliana. DOI: 10.1093/pcp/pcg173 ; PMID: 14701923
- Global analysis of Arabidopsis gene expression uncovers a complex array of changes impacting pathogen response and cell cycle during geminivirus infection. DOI: 10.1104/pp.108.121038 ; PMID: 18650403
- Lutein accumulation in the absence of zeaxanthin restores nonphotochemical quenching in the Arabidopsis thaliana npq1 mutant. DOI: 10.1105/tpc.109.066571 ; PMID: 19549928
- Differential Roles of Carotenes and Xanthophylls in Photosystem I Photoprotection. DOI: 10.1021/acs.biochem.6b00425 ; PMID: 27290879
- A transcriptomics approach uncovers novel roles for poly(ADP-ribosyl)ation in the basal defense response in Arabidopsis thaliana. DOI: 10.1371/journal.pone.0190268 ; PMID: 29284022
- Sorting signals, N-terminal modifications and abundance of the chloroplast proteome. DOI: 10.1371/journal.pone.0001994 ; PMID: 18431481
- Sorting signals, N-terminal modifications and abundance of the chloroplast proteome. DOI: 10.1371/journal.pone.0001994 ; PMID: 18431481
Sequences:
cDNA Sequence
- >AT2G32640.1
TTAATTTTAGAACAGAAGTTTGTTTTGAGTTAATGTAACCCAAAATGTTTTTGTTTTGTAAGACTGTAAACGTGTCACATTCTCTGACACATTGCACAATCTTTCCAGTTTTCTCTTCACAAGTTTTATCTCTGTTTATCAAAAGTTCGCTCTTGGTTTTATAGCATTTGTTTTGGAACTCATTGTCATGGTGGTTCTGCAAATTCATCAGTTCAATGGGTTCGTTAGTTCCGTATCAAGGGCTCAGACAAACCAAGGAAGAAGGAGAGCTTCGACGACAGTGTGCGTTCAAACACAATTGGCTCCCTCTCTTACACAGAAGATAATGGAGAGTATTTCAGTTGGTGGAGAAGCTGGAGGTGCTGGTGGTGCTTACTCTTATAATGCCTTGAAGAGACTTGACAATATTTGGTCCAACATATGTACTCAACCAACAGGACCACAAGAAACTCAGCAAATTGTTTCTAGGGTATCTGGTTTTTCTCAAGATTATAGTATGGGGAATAATCTCGTTGGAACCTTTGACATAGTGGTTTGTGGGGGTACTTTGGGGATTTTTCTAGCCACGGCTCTATGTGCCAAGGGTTTAAGAGTCGCTGTGGTGGAGAGAAATGCAATCAAAGGGAGAGATCAAGAATGGAATATCTCAAGAAAAGAGATGAAAGAACTGACTGAAGTCAGAGTTTTAACCGAAGATGAGATCGAAGAAGTAATTGCTGCAAAGTTCAATCCGAACAGATGTGGATTTGAGAATCTTGGTGATATATGGGTTGAAGATATTCTTAACCTCGGCGTTTCCCCAGCCAAACTTGTGGAAACTGTAAAACAACGTTTCATTTCTCTTGGTGGAGTCATTTTAGAAGACTCCAGCCTCTCGAGCATCGTCATCTACAATGATTTAGCTGTTATGCAACTTTCTAAAGGTGACACATTATCTTCCCGTCTCGTTATTGATGCCATGGGAAACTTTTCTCCTATTCTGAAGCAGATCAAACGTGGTAGAAAGCCAGATGGAATGTGCCTTGTTGTTGGATCTTGTGCTCATGGGTTTAAAGAGAACTCATCAAGCGACGTTATATATAGCAGTTCATCGGTGACCAGAGTTGCAGATTCCAATGTACAACTCTTTTGGGAGGCTTTCCCGGCTGGCTCTGGTCCATTAGACCGCACTACTTACATGTTCACTTACACTGAACCGCAATCAACATCTCCGAGTTTAGAGGATTTACTCGAAGAATACTGGAAACTGATGCCAAAATACCAAGGAGTCTCTCTTGATGAATTGGAAATACTGAGAGTTGTATACGGAATCTTTCCTACATACCGAAATAGTCCGTTGCCAGCTGCATTTGATCGTGTTCTACAGTTTGGTGATGCTAGCGGTATTCAATCACCTGTTTCATTTGGGGGTTTTGGAAGTTTGACCAGACACCTTGGAAGATTGTCCAATGGAATCTATGACGCAATAGATGGAGATCTTCTGGACTCTGACAGCTTATCAAAGCTAAATCCTTATATGCCAAACTTGAGCGCATCATGGCTGTTTCAAAGAGCAATGTCTGCAAAGCAACAGCTCGATGTTTCCCGTGGCTTCACCAATGAGCTTCTCCATGTAAATTTCAGTTGCATGCAGAGATTGGGCGATCCAGTTCTCAGACCATTTCTTCAGGATATAATACAGTTTGGTCCTCTAGCAAAGACATTAGGCCTTGTCATGCTGACCAAACCTCAGATAATTCCGTCAATATTCAGACAGGTTGGGATACCTGTTCTGCTTGATTGGTCTGTTCATTTTTTCATGCTGGGCTTGTATACGCTCCTCTCGGCATACATCGATCCATTGCTAAGGCCGTCTTTGGAAGGACTTCCCTCAAAGACGAGGTTCGAGTGGAAGAGATGTCTCGAGGCCTGGAAATATGGAGCTGGCCTCGATTATGAGTTGTGATTCTGTTCGTATTTCTGAAGAATGGTACCCTCATCGTCACTGGCTTTTTGAAAGAATAAAAGTTCATCAGATATCAACATCTAGTACTTCATAAGCTTCATAAATGTCTGGCTCATATACACAGAATCAACATCTCAATCCTTAGATTTGATTCACAGGGTTCTAGAAAACTCCTTCAATATCAGTTTATACACACCTACATTCGAAAAGCTTTGTTCTATGAACAGACAAATTTATAGTAATTTAATACACCAAAAGCGTCGAGCTTTGTTTTCTTT - >AT2G32640.2
TTAATTTTAGAACAGAAGTTTGTTTTGAGTTAATGTAACCCAAAATGTTTTTGTTTTGTAAGACTGTAAACGTGTCACATTCTCTGACACATTGCACAATCTTTCCAGTTTTCTCTTCACAAGTTTTATCTCTGTTTATCAAAAGTTCGCTCTTGGTTTTATAGCATTTGTTTTGGAACTCATTGTCATGGTGGTTCTGCAAATTCATCAGTTCAATGGGTTCGTTAGTTCCGTATCAAGGGCTCAGACAAACCAAGGAAGAAGGAGAGCTTCGACGACAGTGTGCGTTCAAACACAATTGGCTCCCTCTCTTACACAGAAGATAATGGAGAGTATTTCAGTTGGTGGAGAAGCTGGAGGTGCTGGTGGTGCTTACTCTTATAATGCCTTGAAGAGACTTGACAATATTTGGTCCAACATATGTACTCAACCAACAGGACCACAAGAAACTCAGCAAATTGTTTCTAGGGTATCTGGTTTTTCTCAAGATTATAGTATGGGGAATAATCTCGTTGGAACCTTTGACATAGTGGTTTGTGGGGGTACTTTGGGGATTTTTCTAGCCACGGCTCTATGTGCCAAGGGTTTAAGAGTCGCTGTGGTGGAGAGAAATGCAATCAAAGGGAGAGATCAAGAATGGAATATCTCAAGAAAAGAGATGAAAGAACTGACTGAAGTCAGAGTTTTAACCGAAGATGAGATCGAAGAAGTAATTGCTGCAAAGTTCAATCCGAACAGATGTGGATTTGAGAATCTTGGTGATATATGGGTTGAAGATATTCTTAACCTCGGCGTTTCCCCAGCCAAACTTGTGGAAACTGTAAAACAACGTTTCATTTCTCTTGGTGGAGTCATTTTAGAAGACTCCAGCCTCTCGAGCATCGTCATCTACAATGATTTAGCTGTTATGCAACTTTCTAAAGGTGACACATTATCTTCCCGTCTCGTTATTGATGCCATGGGAAACTTTTCTCCTATTCTGAAGCAGATCAAACGTGGTAGAAAGCCAGATGGAATGTGCCTTGTTGTTGGATCTTGTGCTCATGGGTTTAAAGAGAACTCATCAAGCGACGTTATATATAGCAGTTCATCGGTGACCAGAGTTGCAGATTCCAATGTACAACTCTTTTGGGAGGCTTTCCCGGCTGGCTCTGGTCCATTAGACCGCACTACTTACATGTTCACTTACACTGAACCGCAATCAACATCTCCGAGTTTAGAGGATTTACTCGAAGAATACTGGAAACTGATGCCAAAATACCAAGGAGTCTCTCTTGATGAATTGGAAATACTGAGAGTTGTATACGGAATCTTTCCTACATACCGAAATAGTCCGTTGCCAGCTGCATTTGATCGTGTTCTACAGTTTGGTGATGCTAGCGGTATTCAATCACCTGTTTCATTTGGGGGTTTTGGAAGTTTGACCAGACACCTTGGAAGATTGTCCAATGGAATCTATGACGCAATAGATGGAGATCTTCTGGACTCTGACAGCTTATCAAAGCTAAATCCTTATATGCCAAACTTGAGCGCATCATGGCTGTTTCAAAGAGCAATGTCTGCAAAGCAACAGCTCGATGTTTCCCGTGGCTTCACCAATGAGCTTCTCCATGTAAATTTCAGTTGCATGCAGAGATTGGGCGATCCAGTTCTCAGACCATTTCTTCAGGATATAATACAGTTTGGTCCTCTAGCAAAGACATTAGGCCTTGTCATGCTGACCAAACCTCAGATAATTCCGTCAATATTCAGACAGGTTGGGATACCTGTTCTGCTTGATTGGTCTGTTCATTTTTTCATGCTGGGCTTGTATACGCTCCTCTCGGCATACATCGATCCATTGCTAAGGCCGTCTTTGGAAGGACTTCCCTCAAAGACGAGGTTCGAGTGGAAGAGATGTCTCGAGGCCTGGAAATATGGAGCTGGCCTCGATTATGAGTTGTGATTCTGTTCGTATTTCTGAAGAATGGTACCCTCATCGTCACTGGCTTTTTGAAAGAATAAAAGTTCATCAGATATCAACATCTAGTACTTCATAAGCTTCATAAATGTCTGGCTCATATACACAGAATCAACATCTCAATCCTTAGATTTGATTCACAGGGTTCTAGAAAACTCCTTCAATATCAGTTTATACACACCTACATTCGAAAAGCTTTGTTCTATGAACAGACAAATTTATAGTAATTTAATACACCAAAAGCGTCGAGCTTTGTTTTCTTT
CDS Sequence
- >AT2G32640.1
ATGGTGGTTCTGCAAATTCATCAGTTCAATGGGTTCGTTAGTTCCGTATCAAGGGCTCAGACAAACCAAGGAAGAAGGAGAGCTTCGACGACAGTGTGCGTTCAAACACAATTGGCTCCCTCTCTTACACAGAAGATAATGGAGAGTATTTCAGTTGGTGGAGAAGCTGGAGGTGCTGGTGGTGCTTACTCTTATAATGCCTTGAAGAGACTTGACAATATTTGGTCCAACATATGTACTCAACCAACAGGACCACAAGAAACTCAGCAAATTGTTTCTAGGGTATCTGGTTTTTCTCAAGATTATAGTATGGGGAATAATCTCGTTGGAACCTTTGACATAGTGGTTTGTGGGGGTACTTTGGGGATTTTTCTAGCCACGGCTCTATGTGCCAAGGGTTTAAGAGTCGCTGTGGTGGAGAGAAATGCAATCAAAGGGAGAGATCAAGAATGGAATATCTCAAGAAAAGAGATGAAAGAACTGACTGAAGTCAGAGTTTTAACCGAAGATGAGATCGAAGAAGTAATTGCTGCAAAGTTCAATCCGAACAGATGTGGATTTGAGAATCTTGGTGATATATGGGTTGAAGATATTCTTAACCTCGGCGTTTCCCCAGCCAAACTTGTGGAAACTGTAAAACAACGTTTCATTTCTCTTGGTGGAGTCATTTTAGAAGACTCCAGCCTCTCGAGCATCGTCATCTACAATGATTTAGCTGTTATGCAACTTTCTAAAGGTGACACATTATCTTCCCGTCTCGTTATTGATGCCATGGGAAACTTTTCTCCTATTCTGAAGCAGATCAAACGTGGTAGAAAGCCAGATGGAATGTGCCTTGTTGTTGGATCTTGTGCTCATGGGTTTAAAGAGAACTCATCAAGCGACGTTATATATAGCAGTTCATCGGTGACCAGAGTTGCAGATTCCAATGTACAACTCTTTTGGGAGGCTTTCCCGGCTGGCTCTGGTCCATTAGACCGCACTACTTACATGTTCACTTACACTGAACCGCAATCAACATCTCCGAGTTTAGAGGATTTACTCGAAGAATACTGGAAACTGATGCCAAAATACCAAGGAGTCTCTCTTGATGAATTGGAAATACTGAGAGTTGTATACGGAATCTTTCCTACATACCGAAATAGTCCGTTGCCAGCTGCATTTGATCGTGTTCTACAGTTTGGTGATGCTAGCGGTATTCAATCACCTGTTTCATTTGGGGGTTTTGGAAGTTTGACCAGACACCTTGGAAGATTGTCCAATGGAATCTATGACGCAATAGATGGAGATCTTCTGGACTCTGACAGCTTATCAAAGCTAAATCCTTATATGCCAAACTTGAGCGCATCATGGCTGTTTCAAAGAGCAATGTCTGCAAAGCAACAGCTCGATGTTTCCCGTGGCTTCACCAATGAGCTTCTCCATGTAAATTTCAGTTGCATGCAGAGATTGGGCGATCCAGTTCTCAGACCATTTCTTCAGGATATAATACAGTTTGGTCCTCTAGCAAAGACATTAGGCCTTGTCATGCTGACCAAACCTCAGATAATTCCGTCAATATTCAGACAGGTTGGGATACCTGTTCTGCTTGATTGGTCTGTTCATTTTTTCATGCTGGGCTTGTATACGCTCCTCTCGGCATACATCGATCCATTGCTAAGGCCGTCTTTGGAAGGACTTCCCTCAAAGACGAGGTTCGAGTGGAAGAGATGTCTCGAGGCCTGGAAATATGGAGCTGGCCTCGATTATGAGTTGTGA - >AT2G32640.2
ATGGTGGTTCTGCAAATTCATCAGTTCAATGGGTTCGTTAGTTCCGTATCAAGGGCTCAGACAAACCAAGGAAGAAGGAGAGCTTCGACGACAGTGTGCGTTCAAACACAATTGGCTCCCTCTCTTACACAGAAGATAATGGAGAGTATTTCAGTTGGTGGAGAAGCTGGAGGTGCTGGTGGTGCTTACTCTTATAATGCCTTGAAGAGACTTGACAATATTTGGTCCAACATATGTACTCAACCAACAGGACCACAAGAAACTCAGCAAATTGTTTCTAGGGTATCTGGTTTTTCTCAAGATTATAGTATGGGGAATAATCTCGTTGGAACCTTTGACATAGTGGTTTGTGGGGGTACTTTGGGGATTTTTCTAGCCACGGCTCTATGTGCCAAGGGTTTAAGAGTCGCTGTGGTGGAGAGAAATGCAATCAAAGGGAGAGATCAAGAATGGAATATCTCAAGAAAAGAGATGAAAGAACTGACTGAAGTCAGAGTTTTAACCGAAGATGAGATCGAAGAAGTAATTGCTGCAAAGTTCAATCCGAACAGATGTGGATTTGAGAATCTTGGTGATATATGGGTTGAAGATATTCTTAACCTCGGCGTTTCCCCAGCCAAACTTGTGGAAACTGTAAAACAACGTTTCATTTCTCTTGGTGGAGTCATTTTAGAAGACTCCAGCCTCTCGAGCATCGTCATCTACAATGATTTAGCTGTTATGCAACTTTCTAAAGGTGACACATTATCTTCCCGTCTCGTTATTGATGCCATGGGAAACTTTTCTCCTATTCTGAAGCAGATCAAACGTGGTAGAAAGCCAGATGGAATGTGCCTTGTTGTTGGATCTTGTGCTCATGGGTTTAAAGAGAACTCATCAAGCGACGTTATATATAGCAGTTCATCGGTGACCAGAGTTGCAGATTCCAATGTACAACTCTTTTGGGAGGCTTTCCCGGCTGGCTCTGGTCCATTAGACCGCACTACTTACATGTTCACTTACACTGAACCGCAATCAACATCTCCGAGTTTAGAGGATTTACTCGAAGAATACTGGAAACTGATGCCAAAATACCAAGGAGTCTCTCTTGATGAATTGGAAATACTGAGAGTTGTATACGGAATCTTTCCTACATACCGAAATAGTCCGTTGCCAGCTGCATTTGATCGTGTTCTACAGTTTGGTGATGCTAGCGGTATTCAATCACCTGTTTCATTTGGGGGTTTTGGAAGTTTGACCAGACACCTTGGAAGATTGTCCAATGGAATCTATGACGCAATAGATGGAGATCTTCTGGACTCTGACAGCTTATCAAAGCTAAATCCTTATATGCCAAACTTGAGCGCATCATGGCTGTTTCAAAGAGCAATGTCTGCAAAGCAACAGCTCGATGTTTCCCGTGGCTTCACCAATGAGCTTCTCCATGTAAATTTCAGTTGCATGCAGAGATTGGGCGATCCAGTTCTCAGACCATTTCTTCAGGATATAATACAGTTTGGTCCTCTAGCAAAGACATTAGGCCTTGTCATGCTGACCAAACCTCAGATAATTCCGTCAATATTCAGACAGGTTGGGATACCTGTTCTGCTTGATTGGTCTGTTCATTTTTTCATGCTGGGCTTGTATACGCTCCTCTCGGCATACATCGATCCATTGCTAAGGCCGTCTTTGGAAGGACTTCCCTCAAAGACGAGGTTCGAGTGGAAGAGATGTCTCGAGGCCTGGAAATATGGAGCTGGCCTCGATTATGAGTTGTGA
Protein Sequence
- >AT2G32640.1
MVVLQIHQFNGFVSSVSRAQTNQGRRRASTTVCVQTQLAPSLTQKIMESISVGGEAGGAGGAYSYNALKRLDNIWSNICTQPTGPQETQQIVSRVSGFSQDYSMGNNLVGTFDIVVCGGTLGIFLATALCAKGLRVAVVERNAIKGRDQEWNISRKEMKELTEVRVLTEDEIEEVIAAKFNPNRCGFENLGDIWVEDILNLGVSPAKLVETVKQRFISLGGVILEDSSLSSIVIYNDLAVMQLSKGDTLSSRLVIDAMGNFSPILKQIKRGRKPDGMCLVVGSCAHGFKENSSSDVIYSSSSVTRVADSNVQLFWEAFPAGSGPLDRTTYMFTYTEPQSTSPSLEDLLEEYWKLMPKYQGVSLDELEILRVVYGIFPTYRNSPLPAAFDRVLQFGDASGIQSPVSFGGFGSLTRHLGRLSNGIYDAIDGDLLDSDSLSKLNPYMPNLSASWLFQRAMSAKQQLDVSRGFTNELLHVNFSCMQRLGDPVLRPFLQDIIQFGPLAKTLGLVMLTKPQIIPSIFRQVGIPVLLDWSVHFFMLGLYTLLSAYIDPLLRPSLEGLPSKTRFEWKRCLEAWKYGAGLDYEL - >AT2G32640.2
MVVLQIHQFNGFVSSVSRAQTNQGRRRASTTVCVQTQLAPSLTQKIMESISVGGEAGGAGGAYSYNALKRLDNIWSNICTQPTGPQETQQIVSRVSGFSQDYSMGNNLVGTFDIVVCGGTLGIFLATALCAKGLRVAVVERNAIKGRDQEWNISRKEMKELTEVRVLTEDEIEEVIAAKFNPNRCGFENLGDIWVEDILNLGVSPAKLVETVKQRFISLGGVILEDSSLSSIVIYNDLAVMQLSKGDTLSSRLVIDAMGNFSPILKQIKRGRKPDGMCLVVGSCAHGFKENSSSDVIYSSSSVTRVADSNVQLFWEAFPAGSGPLDRTTYMFTYTEPQSTSPSLEDLLEEYWKLMPKYQGVSLDELEILRVVYGIFPTYRNSPLPAAFDRVLQFGDASGIQSPVSFGGFGSLTRHLGRLSNGIYDAIDGDLLDSDSLSKLNPYMPNLSASWLFQRAMSAKQQLDVSRGFTNELLHVNFSCMQRLGDPVLRPFLQDIIQFGPLAKTLGLVMLTKPQIIPSIFRQVGIPVLLDWSVHFFMLGLYTLLSAYIDPLLRPSLEGLPSKTRFEWKRCLEAWKYGAGLDYEL