Gene Details:

• Gene ID: AT2G32440
• Gene Symbol: ATKAO2, CYP88A4, KAO2
• Gene Name: ARABIDOPSIS ENT-KAURENOIC ACID HYDROXYLASE 2, ent-kaurenoic acid hydroxylase 2
• Description: ent-kaurenoic acid hydroxylase 2;(source:Araport11)
• TAIR Accession: locus:2062623
• Genome: Araport11_genome_release
• Species: Arabidopsis thaliana

Transcripts:

• AT2G32440.1     AT2G32440.2

Plant Ontology Annotations:

• PO:0000013  — cauline leaf — hoja caulinar (Spanish, exact), 茎生葉、茎葉 (Japanese, exact)
• PO:0000014  — rosette leaf — hoja en roseta (Spanish, exact), ロゼット葉 (Japanese, exact)
• PO:0009001  — fruit — frucht (exact, German), fruto (exact, Spanish), 果実 (exact, Japanese), coenocarp (narrow), syncarp (narrow), aggregate fruit (broad), compound fruit (broad), dehiscent fruit (broad), diaspore (broad), indehiscent fruit (broad), multiple fruit (broad), propagule (broad)
• PO:0009047  — stem — caña (Spanish, exact), culm (exact), eje primario (Spanish, exact), primary axis (exact), primary stem (exact), tallo (Spanish, exact), tronco (Spanish, exact), 茎 (Japanese, exact), bole (narrow), cane (narrow), caudex (narrow), caudices (narrow), core (narrow), primocane (narrow), scape (narrow), stalk (narrow), trunk (narrow)
• PO:0009049  — inflorescence — inflorescencia (Spanish, exact), 花序 (Japanese, exact), Triticeae spike (narrow)
• PO:0000037  — shoot axis apex — ápice del epiblasto (epiblastema) (Spanish, exact), シュート頂、茎頂 (Japanese, exact)
• PO:0008019  — leaf lamina base — base de la lámina de la hoja (Spanish, exact), 葉身基部 (Japanese, exact)
• PO:0009005  — root — raíz (Spanish, exact), radices (exact, plural), radix (exact), 根 (Japanese, exact), aerial root (narrow), climbing root (narrow)
• PO:0009006  — shoot system — sistema de epiblasto (epiblastema) (Spanish, exact), シュート系、苗条系 (Japanese, exact), Poaceae crown (related), shoot (related), thalli (related), thallus (related), tree crown (narrow)
• PO:0009009  — plant embryo — embrión (Spanish, exact), 植物胚 (Japanese, exact), germ (related), embryo (broad)
• PO:0009025  — vascular leaf — foliage leaf (exact), hoja vascular (Spanish, exact), leaf, vascular (exact), vascular leaves (exact, plural), 維管束のある葉, または維管束植物の葉 (Japanese, exact), crozier (related), macrophyll (related), megaphyll (related), ascidia (narrow), ascidium (narrow), fiddlehead (narrow), frond (narrow), needle-like leaf (narrow), pitcher (narrow), pitcher blade (narrow), pitcher-blade (narrow), scale-like leaf (narrow), sterile frond (narrow), trophophyll (narrow)
• PO:0009029  — stamen — estambre (Spanish, exact), 雄蕊 (Japanese, exact), Poaceae stamen (narrow), Zea stamen (narrow)
• PO:0009031  — sepal — sépalo (Spanish, exact), がく片 (Japanese, exact)
• PO:0009046  — flower — flor (Spanish, exact), 花 (Japanese, exact), floret (related), Asteraceae floret (narrow), basal flower (narrow), double flower (narrow), hermaphrodite flower (narrow), monoclinous flower (narrow), perfect flower (narrow)
• PO:0009052  — inflorescence flower pedicel — 小花柄 (Japanese, related), pedicelo (Spanish, broad)
• PO:0020030  — cotyledon — cotiledón (Spanish, exact), seed leaf (exact), 子葉 (Japanese, exact)
• PO:0020038  — petiole — pecíolo (Spanish, exact), 葉柄 (Japanese, exact)
• PO:0020100  — hypocotyl — hipocótile (Spanish, exact), 胚軸 (Japanese, exact)
• PO:0020137  — leaf apex — ápice de la hoja (Spanish, exact), 葉先 (Japanese, exact), leaf lamina apex (narrow), phyllid apex (narrow)
• PO:0025022  — collective leaf structure — estructura colectiva de hoja (Spanish, exact), leaf series (exact), 葉が集まった構造 (Japanese, exact), leaf whorl (narrow), rosette (narrow), cycle (broad), verticil (broad)
• PO:0025281  — pollen — polen (Spanish, exact), pollen grain (exact), 花粉 (Japanese, exact)

Gene Ontology:

• GO:0051777  — enables — ent-kaurenoate oxidase activity
• GO:0005739  — located in — mitochondrion
• GO:0007275  — involved in — multicellular organism development
• GO:0009686  — acts upstream of or within — gibberellin biosynthetic process
• GO:0005783  — located in — endoplasmic reticulum
• GO:0016132  — involved in — brassinosteroid biosynthetic process
• GO:0009686  — involved in — gibberellin biosynthetic process
• GO:0016125  — involved in — sterol metabolic process
• GO:0020037  — enables — heme binding
• GO:0005506  — enables — iron ion binding
• GO:0005783  — is active in — endoplasmic reticulum
• GO:0010268  — involved in — brassinosteroid homeostasis

Function-related keywords:

• cauline leaf ,  rosette leaf ,  fruit ,  stem ,  inflorescence ,  shoot axis apex ,  leaf lamina base ,  root ,  shoot system ,  plant embryo ,  vascular leaf ,  stamen ,  sepal ,  flower ,  inflorescence flower pedicel ,  cotyledon ,  petiole ,  hypocotyl ,  leaf apex ,  collective leaf structure ,  pollen ,  pollen

Literature:

• The CYP88A cytochrome P450, ent-kaurenoic acid oxidase, catalyzes three steps of the gibberellin biosynthesis pathway.   DOI:  10.1073/pnas.98.4.2065 ;  PMID:  11172076
• A plastid envelope location of Arabidopsis ent-kaurene oxidase links the plastid and endoplasmic reticulum steps of the gibberellin biosynthesis pathway.   DOI:  10.1046/j.1365-313x.2001.01150.x ;  PMID:  11722763
• Genome organization in Arabidopsis thaliana: a survey for genes involved in isoprenoid and chlorophyll metabolism.   DOI:  10.1023/a:1023005504702 ;  PMID:  12777052
• Gibberellin biosynthesis and response during Arabidopsis seed germination.   DOI:  10.1105/tpc.011650 ;  PMID:  12837949
• Activation of gibberellin biosynthesis and response pathways by low temperature during imbibition of Arabidopsis thaliana seeds.   DOI:  10.1105/tpc.018143 ;  PMID:  14729916
• The involvement of gibberellin 20-oxidase genes in phytochrome-regulated petiole elongation of Arabidopsis.   DOI:  10.1104/pp.104.059055 ;  PMID:  15923331
• Transcriptional profile of the Arabidopsis root quiescent center.   DOI:  10.1105/tpc.105.031724 ;  PMID:  15937229
• Overexpression of ADC2 in Arabidopsis induces dwarfism and late-flowering through GA deficiency.   DOI:  10.1111/j.1365-313X.2005.02465.x ;  PMID:  16045477
• WRKY70 modulates the selection of signaling pathways in plant defense.   DOI:  10.1111/j.1365-313X.2006.02712.x ;  PMID:  16623907
• Mapping the Arabidopsis organelle proteome.   DOI:  10.1073/pnas.0506958103 ;  PMID:  16618929
• Global analysis of Arabidopsis gene expression uncovers a complex array of changes impacting pathogen response and cell cycle during geminivirus infection.   DOI:  10.1104/pp.108.121038 ;  PMID:  18650403
• Dynamic landscapes of four histone modifications during deetiolation in Arabidopsis.   DOI:  10.1105/tpc.109.066845 ;  PMID:  20008096
• The gibberellin biosynthetic genes AtKAO1 and AtKAO2 have overlapping roles throughout Arabidopsis development.   DOI:  10.1111/tpj.12648 ;  PMID:  25146977
• The CYP88A cytochrome P450, ent-kaurenoic acid oxidase, catalyzes three steps of the gibberellin biosynthesis pathway.   DOI:  10.1073/pnas.98.4.2065 ;  PMID:  11172076
• Mapping the Arabidopsis organelle proteome.   DOI:  10.1073/pnas.0506958103 ;  PMID:  16618929

Sequences: