Gene Details:

• Gene ID: AT2G31870
• Gene Symbol: atPARG1, PARG1, TEJ
• Gene Name: poly(ADP-ribose) glycohydrolase 1, Sanskrit for bright
• Description: Poly (ADP-ribose) glycohydrolase (PARG);(source:Araport11)
• TAIR Accession: locus:2045243
• Genome: Araport11_genome_release
• Species: Arabidopsis thaliana

Transcripts:

• AT2G31870.1     AT2G31870.2

Plant Ontology Annotations:

• PO:0000037  — shoot axis apex — ápice del epiblasto (epiblastema) (Spanish, exact), シュート頂、茎頂 (Japanese, exact)
• PO:0008019  — leaf lamina base — base de la lámina de la hoja (Spanish, exact), 葉身基部 (Japanese, exact)
• PO:0009005  — root — raíz (Spanish, exact), radices (exact, plural), radix (exact), 根 (Japanese, exact), aerial root (narrow), climbing root (narrow)
• PO:0009006  — shoot system — sistema de epiblasto (epiblastema) (Spanish, exact), シュート系、苗条系 (Japanese, exact), Poaceae crown (related), shoot (related), thalli (related), thallus (related), tree crown (narrow)
• PO:0009009  — plant embryo — embrión (Spanish, exact), 植物胚 (Japanese, exact), germ (related), embryo (broad)
• PO:0009025  — vascular leaf — foliage leaf (exact), hoja vascular (Spanish, exact), leaf, vascular (exact), vascular leaves (exact, plural), 維管束のある葉, または維管束植物の葉 (Japanese, exact), crozier (related), macrophyll (related), megaphyll (related), ascidia (narrow), ascidium (narrow), fiddlehead (narrow), frond (narrow), needle-like leaf (narrow), pitcher (narrow), pitcher blade (narrow), pitcher-blade (narrow), scale-like leaf (narrow), sterile frond (narrow), trophophyll (narrow)
• PO:0009029  — stamen — estambre (Spanish, exact), 雄蕊 (Japanese, exact), Poaceae stamen (narrow), Zea stamen (narrow)
• PO:0009031  — sepal — sépalo (Spanish, exact), がく片 (Japanese, exact)
• PO:0009046  — flower — flor (Spanish, exact), 花 (Japanese, exact), floret (related), Asteraceae floret (narrow), basal flower (narrow), double flower (narrow), hermaphrodite flower (narrow), monoclinous flower (narrow), perfect flower (narrow)
• PO:0009052  — inflorescence flower pedicel — 小花柄 (Japanese, related), pedicelo (Spanish, broad)
• PO:0020030  — cotyledon — cotiledón (Spanish, exact), seed leaf (exact), 子葉 (Japanese, exact)
• PO:0020038  — petiole — pecíolo (Spanish, exact), 葉柄 (Japanese, exact)
• PO:0020100  — hypocotyl — hipocótile (Spanish, exact), 胚軸 (Japanese, exact)
• PO:0020137  — leaf apex — ápice de la hoja (Spanish, exact), 葉先 (Japanese, exact), leaf lamina apex (narrow), phyllid apex (narrow)
• PO:0025022  — collective leaf structure — estructura colectiva de hoja (Spanish, exact), leaf series (exact), 葉が集まった構造 (Japanese, exact), leaf whorl (narrow), rosette (narrow), cycle (broad), verticil (broad)
• PO:0025281  — pollen — polen (Spanish, exact), pollen grain (exact), 花粉 (Japanese, exact)

Gene Ontology:

• GO:0004649  — enables — poly(ADP-ribose) glycohydrolase activity
• GO:0006282  — involved in — regulation of DNA repair
• GO:0009414  — acts upstream of or within — response to water deprivation
• GO:0006282  — acts upstream of or within — regulation of DNA repair
• GO:0006974  — acts upstream of or within — DNA damage response
• GO:0050832  — acts upstream of or within — defense response to fungus
• GO:0005634  — located in — nucleus
• GO:0006970  — acts upstream of or within — response to osmotic stress
• GO:0006979  — acts upstream of or within — response to oxidative stress
• GO:0090332  — acts upstream of or within — stomatal closure
• GO:0009225  — involved in — nucleotide-sugar metabolic process
• GO:0005975  — involved in — carbohydrate metabolic process
• GO:0005737  — is active in — cytoplasm
• GO:0005634  — is active in — nucleus
• GO:1990966  — involved in — ATP generation from poly-ADP-D-ribose

Germplasm Phenotype:

• SALK_012110C  — Mutants accumulate poly(ADP-ribose) and are hypersensitive to bleomycin. Loss of function of PARG1 leads to severe cell death after bleomycin treatment.Mutants also have increased levels of ATM, ATR and SOG1 when plants are treated with bleomycin.
• tej  — Long free-running circadian period
• tej-1  — significantly greater WUE

Function-related keywords:

• shoot axis apex ,  leaf lamina base ,  root ,  shoot system ,  plant embryo ,  vascular leaf ,  stamen ,  sepal ,  flower ,  inflorescence flower pedicel ,  cotyledon ,  petiole ,  hypocotyl ,  leaf apex ,  collective leaf structure ,  pollen

Literature:

• tej defines a role for poly(ADP-ribosyl)ation in establishing period length of the arabidopsis circadian oscillator.   DOI:  10.1016/s1534-5807(02)00200-9 ;  PMID:  12110167
• ATR and ATM play both distinct and additive roles in response to ionizing radiation.   DOI:  10.1111/j.1365-313X.2006.02931.x ;  PMID:  17227549
• Disruption of poly(ADP-ribosyl)ation mechanisms alters responses of Arabidopsis to biotic stress.   DOI:  10.1104/pp.109.148049 ;  PMID:  19889874
• Protein poly(ADP-ribosyl)ation regulates arabidopsis immune gene expression and defense responses.   DOI:  10.1371/journal.pgen.1004936 ;  PMID:  25569773
• PARP2 Is the Predominant Poly(ADP-Ribose) Polymerase in Arabidopsis DNA Damage and Immune Responses.   DOI:  10.1371/journal.pgen.1005200 ;  PMID:  25950582
• Arabidopsis PARG1 is the key factor promoting cell survival among the enzymes regulating post-translational poly(ADP-ribosyl)ation.   DOI:  10.1038/srep15892 ;  PMID:  26516022
• A transcriptomics approach uncovers novel roles for poly(ADP-ribosyl)ation in the basal defense response in Arabidopsis thaliana.   DOI:  10.1371/journal.pone.0190268 ;  PMID:  29284022
• The Circadian Clock Influences the Long-Term Water Use Efficiency of Arabidopsis.   DOI:  10.1104/pp.20.00030 ;  PMID:  32179629
• Noncanonical mono(ADP-ribosyl)ation of zinc finger SZF proteins counteracts ubiquitination for protein homeostasis in plant immunity.   DOI:  10.1016/j.molcel.2021.09.006 ;  PMID:  34592134

Sequences: