Gene Details:

• Gene ID: AT2G31320
• Gene Symbol: PARP1
• Gene Name: POLY(ADP-RIBOSE) POLYMERASE 1
• Description: poly(ADP-ribose) polymerase 2;(source:Araport11)
• TAIR Accession: locus:2042511
• Genome: Araport11_genome_release
• Species: Arabidopsis thaliana

Transcripts:

• AT2G31320.1

Plant Ontology Annotations:

• PO:0000037  — shoot axis apex — ápice del epiblasto (epiblastema) (Spanish, exact), シュート頂、茎頂 (Japanese, exact)
• PO:0008019  — leaf lamina base — base de la lámina de la hoja (Spanish, exact), 葉身基部 (Japanese, exact)
• PO:0009005  — root — raíz (Spanish, exact), radices (exact, plural), radix (exact), 根 (Japanese, exact), aerial root (narrow), climbing root (narrow)
• PO:0009006  — shoot system — sistema de epiblasto (epiblastema) (Spanish, exact), シュート系、苗条系 (Japanese, exact), Poaceae crown (related), shoot (related), thalli (related), thallus (related), tree crown (narrow)
• PO:0009009  — plant embryo — embrión (Spanish, exact), 植物胚 (Japanese, exact), germ (related), embryo (broad)
• PO:0009025  — vascular leaf — foliage leaf (exact), hoja vascular (Spanish, exact), leaf, vascular (exact), vascular leaves (exact, plural), 維管束のある葉, または維管束植物の葉 (Japanese, exact), crozier (related), macrophyll (related), megaphyll (related), ascidia (narrow), ascidium (narrow), fiddlehead (narrow), frond (narrow), needle-like leaf (narrow), pitcher (narrow), pitcher blade (narrow), pitcher-blade (narrow), scale-like leaf (narrow), sterile frond (narrow), trophophyll (narrow)
• PO:0009029  — stamen — estambre (Spanish, exact), 雄蕊 (Japanese, exact), Poaceae stamen (narrow), Zea stamen (narrow)
• PO:0009031  — sepal — sépalo (Spanish, exact), がく片 (Japanese, exact)
• PO:0009046  — flower — flor (Spanish, exact), 花 (Japanese, exact), floret (related), Asteraceae floret (narrow), basal flower (narrow), double flower (narrow), hermaphrodite flower (narrow), monoclinous flower (narrow), perfect flower (narrow)
• PO:0009052  — inflorescence flower pedicel — 小花柄 (Japanese, related), pedicelo (Spanish, broad)
• PO:0020038  — petiole — pecíolo (Spanish, exact), 葉柄 (Japanese, exact)
• PO:0020100  — hypocotyl — hipocótile (Spanish, exact), 胚軸 (Japanese, exact)
• PO:0020137  — leaf apex — ápice de la hoja (Spanish, exact), 葉先 (Japanese, exact), leaf lamina apex (narrow), phyllid apex (narrow)
• PO:0025022  — collective leaf structure — estructura colectiva de hoja (Spanish, exact), leaf series (exact), 葉が集まった構造 (Japanese, exact), leaf whorl (narrow), rosette (narrow), cycle (broad), verticil (broad)
• PO:0000084  — plant sperm cell — célula espermática o esperma (Spanish, exact), male gamete (exact), microgamete (exact), 植物精子細胞 (Japanese, exact), sperm nucleus (related), sperm cell (broad)

Gene Ontology:

• GO:0006281  — acts upstream of or within — DNA repair
• GO:0009737  — acts upstream of or within — response to abscisic acid
• GO:0030592  — acts upstream of or within — DNA ADP-ribosylation
• GO:0051287  — enables — NAD binding
• GO:0006302  — involved in — double-strand break repair
• GO:0005730  — is active in — nucleolus
• GO:0008270  — enables — zinc ion binding
• GO:0005634  — located in — nucleus
• GO:0003950  — enables — NAD+ ADP-ribosyltransferase activity
• GO:0006979  — acts upstream of or within — response to oxidative stress
• GO:1990404  — enables — NAD+-protein ADP-ribosyltransferase activity

Function-related keywords:

• shoot axis apex ,  leaf lamina base ,  root ,  shoot system ,  plant embryo ,  vascular leaf ,  stamen ,  sepal ,  flower ,  inflorescence flower pedicel ,  petiole ,  hypocotyl ,  leaf apex ,  collective leaf structure ,  plant sperm cell

Literature:

• Ionising radiation induces the expression of PARP-1 and PARP-2 genes in Arabidopsis.   DOI:  10.1007/s004380100506 ;  PMID:  11523787
• A nick-sensing DNA 3'-repair enzyme from Arabidopsis.   DOI:  10.1074/jbc.M201411200 ;  PMID:  11948185
• a high-density colony array study (HDCA).   DOI:  10.1046/j.1365-313x.2003.01847.x ;  PMID:  12969430
• Inactivation of the chloroplast ATP synthase gamma subunit results in high non-photochemical fluorescence quenching and altered nuclear gene expression in Arabidopsis thaliana.   DOI:  10.1074/jbc.M308435200 ;  PMID:  14576160
• Transcriptional profile of the Arabidopsis root quiescent center.   DOI:  10.1105/tpc.105.031724 ;  PMID:  15937229
• ATR and ATM play both distinct and additive roles in response to ionizing radiation.   DOI:  10.1111/j.1365-313X.2006.02931.x ;  PMID:  17227549
• Silencing of poly(ADP-ribose) polymerase in plants alters abiotic stress signal transduction.   DOI:  10.1073/pnas.0706668104 ;  PMID:  17823244
• Global analysis of Arabidopsis gene expression uncovers a complex array of changes impacting pathogen response and cell cycle during geminivirus infection.   DOI:  10.1104/pp.108.121038 ;  PMID:  18650403
• Poly(ADP-ribose) polymerase in plants affects energy homeostasis, cell death and stress tolerance.   DOI:  10.1111/j.1365-313X.2004.02277.x ;  PMID:  15610352
• Pyridine nucleotide cycling and control of intracellular redox state in relation to poly (ADP-ribose) polymerase activity and nuclear localization of glutathione during exponential growth of Arabidopsis cells in culture.   DOI:  10.1093/mp/ssp008 ;  PMID:  19825628
• Arabidopsis homologues of the histone chaperone ASF1 are crucial for chromatin replication and cell proliferation in plant development.   DOI:  10.1111/j.1365-313X.2011.04504.x ;  PMID:  21251110
• Endogenous protein mono-ADP-ribosylation in Arabidopsis thaliana.   DOI:  10.1007/s00425-011-1415-y ;  PMID:  21519881
• Systematic identification of functional plant modules through the integration of complementary data sources.   DOI:  10.1104/pp.112.196725 ;  PMID:  22589469
• Poly(ADP-ribose)polymerases are involved in microhomology mediated back-up non-homologous end joining in Arabidopsis thaliana.   DOI:  10.1007/s11103-013-0065-9 ;  PMID:  23625359
• Analysis of poly(ADP-Ribose) polymerases in Arabidopsis telomere biology.   DOI:  10.1371/journal.pone.0088872 ;  PMID:  24551184
• PARP2 Is the Predominant Poly(ADP-Ribose) Polymerase in Arabidopsis DNA Damage and Immune Responses.   DOI:  10.1371/journal.pgen.1005200 ;  PMID:  25950582
• Arabidopsis PARG1 is the key factor promoting cell survival among the enzymes regulating post-translational poly(ADP-ribosyl)ation.   DOI:  10.1038/srep15892 ;  PMID:  26516022
• Analysis of knockout mutants reveals non-redundant functions of poly(ADP-ribose)polymerase isoforms in Arabidopsis.   DOI:  10.1007/s11103-015-0363-5 ;  PMID:  26428915
• CRISPR/Cas9-Induced Double-Strand Break Repair in Arabidopsis Nonhomologous End-Joining Mutants.   DOI:  10.1534/g3.116.035204 ;  PMID:  27866150
• Function of the Plant DNA Polymerase Epsilon in Replicative Stress Sensing, a Genetic Analysis.   DOI:  10.1104/pp.17.00031 ;  PMID:  28153919
• Canonical Poly(ADP-Ribose) Polymerases (PARPs) Are No Universal Factors of Abiotic and Biotic Stress Resistance of Arabidopsis thaliana.   DOI:  10.3389/fpls.2017.00059 ;  PMID:  28220129
• A yeast growth assay to characterize plant poly(ADP-ribose) polymerase (PARP) proteins and inhibitors.   DOI:  10.1016/j.ab.2017.04.002 ;  PMID:  28408182
• The Absence of the Arabidopsis Chaperone Complex CAF-1 Produces Mitotic Chromosome Abnormalities and Changes in the Expression Profiles of Genes Involved in DNA Repair.   DOI:  10.3389/fpls.2017.00525 ;  PMID:  28443118
• Transcriptome-based biological dosimetry of gamma radiation in Arabidopsis using DNA damage response genes.   DOI:  10.1016/j.jenvrad.2017.11.007 ;  PMID:  29128690
• Nuclear Import of Arabidopsis Poly(ADP-Ribose) Polymerase 2 Is Mediated by Importin-α and a Nuclear Localization Sequence Located Between the Predicted SAP Domains.   DOI:  10.3389/fpls.2018.01581 ;  PMID:  30455710
• SOG1-dependent NAC103 modulates the DNA damage response as a transcriptional regulator in Arabidopsis.   DOI:  10.1111/tpj.14201 ;  PMID:  30554433
• Poly(ADP-Ribose) Polymerases in Plants and Their Human Counterparts: Parallels and Peculiarities.   DOI:  10.3390/ijms20071638 ;  PMID:  30986964
• New perspectives on the plant PARP family: Arabidopsis PARP3 is inactive, and PARP1 exhibits predominant poly (ADP-ribose) polymerase activity in response to DNA damage.   DOI:  10.1186/s12870-019-1958-9 ;  PMID:  31426748
• The plant WEE1 kinase is involved in checkpoint control activation in nematode-induced galls.   DOI:  10.1111/nph.16185 ;  PMID:  31505035
• The Arabidopsis thaliana Poly(ADP-Ribose) Polymerases 1 and 2 Modify DNA by ADP-Ribosylating Terminal Phosphate Residues.   DOI:  10.3389/fcell.2020.606596 ;  PMID:  33324653
• Detection of Genes in Arabidopsis thaliana L. Responding to DNA Damage from Radiation and Other Stressors in Spaceflight.   DOI:  10.3390/genes12060938 ;  PMID:  34205326
• Coordinated regulation of plant immunity by poly(ADP-ribosyl)ation and K63-linked ubiquitination.   DOI:  10.1016/j.molp.2021.08.013 ;  PMID:  34418551
• Ionising radiation induces the expression of PARP-1 and PARP-2 genes in Arabidopsis.   DOI:  10.1007/s004380100506 ;  PMID:  11523787

Sequences: