Gene Details:
- Gene ID: AT2G30770
- Gene Symbol: CYP71A13
- Gene Name: cytochrome P450, family 71, subfamily A, polypeptide 13
- Description: cytochrome P450 family 71 polypeptide;(source:Araport11)
- TAIR Accession:
- Genome: Araport11_genome_release
- Species: Arabidopsis thaliana
Transcripts:
Plant Ontology Annotations:
- PO:0008019 — leaf lamina base — base de la lámina de la hoja (Spanish, exact), 葉身基部 (Japanese, exact)
- PO:0009025 — vascular leaf — foliage leaf (exact), hoja vascular (Spanish, exact), leaf, vascular (exact), vascular leaves (exact, plural), 維管束のある葉, または維管束植物の葉 (Japanese, exact), crozier (related), macrophyll (related), megaphyll (related), ascidia (narrow), ascidium (narrow), fiddlehead (narrow), frond (narrow), needle-like leaf (narrow), pitcher (narrow), pitcher blade (narrow), pitcher-blade (narrow), scale-like leaf (narrow), sterile frond (narrow), trophophyll (narrow)
- PO:0009029 — stamen — estambre (Spanish, exact), 雄蕊 (Japanese, exact), Poaceae stamen (narrow), Zea stamen (narrow)
- PO:0009031 — sepal — sépalo (Spanish, exact), がく片 (Japanese, exact)
- PO:0020030 — cotyledon — cotiledón (Spanish, exact), seed leaf (exact), 子葉 (Japanese, exact)
- PO:0025022 — collective leaf structure — estructura colectiva de hoja (Spanish, exact), leaf series (exact), 葉が集まった構造 (Japanese, exact), leaf whorl (narrow), rosette (narrow), cycle (broad), verticil (broad)
Germplasm Phenotype:
- CS72340 — reduced camalexin production
- cyp71A13-1 — When droplets of the necrotrophic fungi Alternaria brassicicola (10 &
- cyp71A13-1 — When indole-3-acetonitrile (IAN) was applied to silver nitrate-treated cyp71A13 leaves, camalexin levels were approximately sixfold higher than when water was applied.
- cyp71A13-1 — When infected with Alternaria brassicicola or Pseudomonas syringae, camalexin levels in infected cyp71A13 mutants were <20% of wild-type levels, even though the ratio of infected to uninfected leaf area was much larger in the mutants than in the wild type.
- cyp71A13-2 — When droplets of the necrotrophic fungi Alternaria brassicicola (10 &
- cyp71A13-2 — When infected with Alternaria brassicicola or Pseudomonas syringae, camalexin levels in infected cyp71A13 mutants were <20% of wild-type levels, even though the ratio of infected to uninfected leaf area was much larger in the mutants than in the wild type.
Function-related keywords:
Literature:
- Changes in gene expression in response to altered SHL transcript levels. DOI: 10.1023/B:PLAN.0000023661.65248.4b ; PMID: 15082927
- Catalase deficiency drastically affects gene expression induced by high light in Arabidopsis thaliana. DOI: 10.1111/j.1365-313X.2004.02105.x ; PMID: 15200641
- An inducible targeted tagging system for localized saturation mutagenesis in Arabidopsis. DOI: 10.1104/pp.104.050633 ; PMID: 15644463
- The association among gene expression responses to nine abiotic stress treatments in Arabidopsis thaliana. DOI: 10.1534/genetics.106.061374 ; PMID: 17028338
- Arabidopsis cytochrome P450 monooxygenase 71A13 catalyzes the conversion of indole-3-acetaldoxime in camalexin synthesis. DOI: 10.1105/tpc.107.051383 ; PMID: 17573535
- Transcript profiling of the hypomethylated hog1 mutant of Arabidopsis. DOI: 10.1007/s11103-007-9221-4 ; PMID: 17786563
- Global analysis of Arabidopsis gene expression uncovers a complex array of changes impacting pathogen response and cell cycle during geminivirus infection. DOI: 10.1104/pp.108.121038 ; PMID: 18650403
- Activation of MAPK kinase 9 induces ethylene and camalexin biosynthesis and enhances sensitivity to salt stress in Arabidopsis. DOI: 10.1074/jbc.M801392200 ; PMID: 18693252
- The ABC transporter BcatrB from Botrytis cinerea exports camalexin and is a virulence factor on Arabidopsis thaliana. DOI: 10.1111/j.1365-313X.2009.03794.x ; PMID: 19154205
- The multifunctional enzyme CYP71B15 (PHYTOALEXIN DEFICIENT3) converts cysteine-indole-3-acetonitrile to camalexin in the indole-3-acetonitrile metabolic network of Arabidopsis thaliana. DOI: 10.1105/tpc.109.066670 ; PMID: 19567706
- Controlled indole-3-acetaldoxime production through ethanol-induced expression of CYP79B2. DOI: 10.1007/s00425-009-0907-5 ; PMID: 19263076
- Transcriptional reprogramming regulated by WRKY18 and WRKY40 facilitates powdery mildew infection of Arabidopsis. DOI: 10.1111/j.1365-313X.2010.04387.x ; PMID: 21143673
- Glutathione-indole-3-acetonitrile is required for camalexin biosynthesis in Arabidopsis thaliana. DOI: 10.1105/tpc.110.079145 ; PMID: 21239642
- Constitutive expression of MKS1 confers susceptibility to Botrytis cinerea infection independent of PAD3 expression. DOI: 10.4161/psb.6.10.16759 ; PMID: 21900742
- Identification and characterization of ANAC042, a transcription factor family gene involved in the regulation of camalexin biosynthesis in Arabidopsis. DOI: 10.1094/MPMI-09-11-0244 ; PMID: 22295908
- Arabidopsis acetyl-amido synthetase GH3.5 involvement in camalexin biosynthesis through conjugation of indole-3-carboxylic acid and cysteine and upregulation of camalexin biosynthesis genes. DOI: 10.1111/j.1744-7909.2012.01131.x ; PMID: 22624950
- Indole-3-acetaldoxime-derived compounds restrict root colonization in the beneficial interaction between Arabidopsis roots and the endophyte Piriformospora indica. DOI: 10.1094/MPMI-03-12-0071-R ; PMID: 22852809
- Metabolic and transcriptomic changes induced in Arabidopsis by the rhizobacterium Pseudomonas fluorescens SS101. DOI: 10.1104/pp.112.207324 ; PMID: 23073694
- Trichoderma-plant root colonization: escaping early plant defense responses and activation of the antioxidant machinery for saline stress tolerance. DOI: 10.1371/journal.ppat.1003221 ; PMID: 23516362
- De novo genetic engineering of the camalexin biosynthetic pathway. DOI: 10.1016/j.jbiotec.2013.06.013 ; PMID: 23830903
- Minimum set of cytochromes P450 for reconstituting the biosynthesis of camalexin, a major Arabidopsis antibiotic. DOI: 10.1002/anie.201307454 ; PMID: 24151049
- TRANSCRIPTION ACTIVATOR-LIKE EFFECTOR NUCLEASE-Mediated Generation and Metabolic Analysis of Camalexin-Deficient cyp71a12 cyp71a13 Double Knockout Lines. DOI: 10.1104/pp.15.00481 ; PMID: 25953104
- Camalexin contributes to the partial resistance of Arabidopsis thaliana to the biotrophic soilborne protist Plasmodiophora brassicae. DOI: 10.3389/fpls.2015.00539 ; PMID: 26257750
- The role of MYB34, MYB51 and MYB122 in the regulation of camalexin biosynthesis in Arabidopsis thaliana. DOI: 10.3389/fpls.2015.00654 ; PMID: 26379682
- Functional interpretation and structural insights of Arabidopsis lyrata cytochrome P450 CYP71A13 involved in auxin synthesis. DOI: 10.6026/97320630011330 ; PMID: 26339148
- Determination of histone epigenetic marks in Arabidopsis and tomato genes in the early response to Botrytis cinerea. DOI: 10.1007/s00299-017-2218-9 ; PMID: 29119291
- Dissection of the network of indolic defence compounds in Arabidopsis thaliana by multiple mutant analysis. DOI: 10.1016/j.phytochem.2019.01.009 ; PMID: 30798200
- Root-specific camalexin biosynthesis controls the plant growth-promoting effects of multiple bacterial strains. DOI: 10.1073/pnas.1818604116 ; PMID: 31311863
- The role of CYP71A12 monooxygenase in pathogen-triggered tryptophan metabolism and Arabidopsis immunity. DOI: 10.1111/nph.16118 ; PMID: 31411742
- The Formation of a Camalexin Biosynthetic Metabolon. DOI: 10.1105/tpc.19.00403 ; PMID: 31511315
- Tryptophan-derived metabolites and BAK1 separately contribute to Arabidopsis postinvasive immunity against Alternaria brassicicola. DOI: 10.1038/s41598-020-79562-x ; PMID: 33452278
- Metabolite profiling reveals a role for intercellular dihydrocamalexic acid in the response of mature Arabidopsis thaliana to Pseudomonas syringae. DOI: 10.1016/j.phytochem.2021.112747 ; PMID: 33823457
- MPK3/MPK6-mediated phosphorylation of ERF72 positively regulates resistance to Botrytis cinerea through directly and indirectly activating the transcription of camalexin biosynthesis enzymes. DOI: 10.1093/jxb/erab415 ; PMID: 34499162
- Multiple indole glucosinolates and myrosinases defend Arabidopsis against Tetranychus urticae herbivory. DOI: 10.1093/plphys/kiab247 ; PMID: 34618148
- A 5' tRNA-Ala-derived small RNA regulates anti-fungal defense in plants. DOI: 10.1007/s11427-021-2017-1 ; PMID: 34705222
- AIG2A and AIG2B limit the activation of salicylic acid-regulated defenses by tryptophan-derived secondary metabolism in Arabidopsis. DOI: 10.1093/plcell/koac255 ; PMID: 35972413
- Shoot-root interaction in control of camalexin exudation in Arabidopsis. DOI: 10.1093/jxb/erad031 ; PMID: 36651631
Sequences:
cDNA Sequence
- >AT2G30770.1
ATGGAAATGATATTGAGTATCTCTTTGTGCTTAACGACCCTCATAACCCTTCTCTTGCTGAGGCGATTCCTCAAACGAACCGCCACTAAAGTGAACCTACCACCATCTCCATGGAGGCTTCCGGTGATCGGAAACCTCCACCAGCTGAGCCTCCATCCTCACCGTTCCCTCCGGTCCCTCAGTCTCAGGTACGGACCACTCATGCTCCTTCATTTTGGCCGTGTCCCTATACTCGTAGTCTCCTCCGGTGAAGCAGCTCAAGAGGTATTGAAAACACATGATCATAAATTTGCGAACCGCCCGAGATCAAAAGCCGTTCATGGGCTTATGAATGGTGGACGTGATGTTGTGTTTGCTCCCTATGGAGAATACTGGAGACAGATGAAGAGTGTATGCATTCTCAATCTGCTCACCAACAAAATGGTTGAATCCTTTGAGAAGGTAAGAGAAGACGAGGTAAATGCAATGATCGAGAAGCTGGAGAAAGCAAGTTCTTCTTCTTCATCAGAAAATCTGAGCGAACTCTTTATAACTCTACCAAGCGATGTTACGAGTAGAGTTGCGTTGGGAAGAAAACATAGCGAGGACGAGACCGCAAGGGATCTCAAGAAGCGAGTGAGGCAGATCATGGAGCTTTTAGGCGAGTTCCCGATCGGGGAATATGTCCCCATATTGGCATGGATAGATGGGATCCGTGGTTTCAATAATAAAATTAAGGAAGTGAGTCGAGGGTTTAGCGATCTTATGGACAAAGTGGTGCAAGAACATTTAGAGGCGAGTAACGATAAAGCGGATTTCGTGGATATATTGTTATCAATCGAAAAAGATAAGAACAGTGGATTCCAAGTTCAAAGAAACGACATAAAATTTATGATCTTGGATATGTTTATCGGAGGAACGTCAACAACTTCGACTCTACTAGAATGGACGATGACGGAACTGATCAGAAGTCCAAAGAGTATGAAGAAACTCCAAGACGAGATTCGGTCAACTATTAGGCCACATGGTTCATACATAAAAGAAAAAGAAGTGGAAAATATGAAATACTTAAAAGCCGTGATTAAAGAGGTGCTTCGGTTGCATCCTTCTCTTCCAATGATACTTCCCAGACTCTTAAGTGAAGATGTCAAAGTAAAGGGATATAACATAGCCGCAGGGACAGAGGTGATAATCAATGCTTGGGCGATCCAACGAGACACTGCGATATGGGGACCGGATGCTGAAGAATTCAAACCGGAGAGACACTTAGATTCAGGTTTAGATTATCACGGAAAAAATCTGAACTACATCCCATTCGGATCAGGGAGAAGGATATGCCCCGGGATAAATCTTGCTTTGGGTCTGGCAGAGGTGACAGTGGCCAACCTTGTAGGCCGATTTGACTGGAGGGTAGAGGCTGGACCAAATGGGGATCAACCTGATCTAACTGAAGCCATTGGTATCGATGTTTGCCGCAAATTCCCTCTCATTGCATTTCCATCTTCGGTTGTGTAA
CDS Sequence
- >AT2G30770.1
ATGGAAATGATATTGAGTATCTCTTTGTGCTTAACGACCCTCATAACCCTTCTCTTGCTGAGGCGATTCCTCAAACGAACCGCCACTAAAGTGAACCTACCACCATCTCCATGGAGGCTTCCGGTGATCGGAAACCTCCACCAGCTGAGCCTCCATCCTCACCGTTCCCTCCGGTCCCTCAGTCTCAGGTACGGACCACTCATGCTCCTTCATTTTGGCCGTGTCCCTATACTCGTAGTCTCCTCCGGTGAAGCAGCTCAAGAGGTATTGAAAACACATGATCATAAATTTGCGAACCGCCCGAGATCAAAAGCCGTTCATGGGCTTATGAATGGTGGACGTGATGTTGTGTTTGCTCCCTATGGAGAATACTGGAGACAGATGAAGAGTGTATGCATTCTCAATCTGCTCACCAACAAAATGGTTGAATCCTTTGAGAAGGTAAGAGAAGACGAGGTAAATGCAATGATCGAGAAGCTGGAGAAAGCAAGTTCTTCTTCTTCATCAGAAAATCTGAGCGAACTCTTTATAACTCTACCAAGCGATGTTACGAGTAGAGTTGCGTTGGGAAGAAAACATAGCGAGGACGAGACCGCAAGGGATCTCAAGAAGCGAGTGAGGCAGATCATGGAGCTTTTAGGCGAGTTCCCGATCGGGGAATATGTCCCCATATTGGCATGGATAGATGGGATCCGTGGTTTCAATAATAAAATTAAGGAAGTGAGTCGAGGGTTTAGCGATCTTATGGACAAAGTGGTGCAAGAACATTTAGAGGCGAGTAACGATAAAGCGGATTTCGTGGATATATTGTTATCAATCGAAAAAGATAAGAACAGTGGATTCCAAGTTCAAAGAAACGACATAAAATTTATGATCTTGGATATGTTTATCGGAGGAACGTCAACAACTTCGACTCTACTAGAATGGACGATGACGGAACTGATCAGAAGTCCAAAGAGTATGAAGAAACTCCAAGACGAGATTCGGTCAACTATTAGGCCACATGGTTCATACATAAAAGAAAAAGAAGTGGAAAATATGAAATACTTAAAAGCCGTGATTAAAGAGGTGCTTCGGTTGCATCCTTCTCTTCCAATGATACTTCCCAGACTCTTAAGTGAAGATGTCAAAGTAAAGGGATATAACATAGCCGCAGGGACAGAGGTGATAATCAATGCTTGGGCGATCCAACGAGACACTGCGATATGGGGACCGGATGCTGAAGAATTCAAACCGGAGAGACACTTAGATTCAGGTTTAGATTATCACGGAAAAAATCTGAACTACATCCCATTCGGATCAGGGAGAAGGATATGCCCCGGGATAAATCTTGCTTTGGGTCTGGCAGAGGTGACAGTGGCCAACCTTGTAGGCCGATTTGACTGGAGGGTAGAGGCTGGACCAAATGGGGATCAACCTGATCTAACTGAAGCCATTGGTATCGATGTTTGCCGCAAATTCCCTCTCATTGCATTTCCATCTTCGGTTGTGTAA
Protein Sequence
- >AT2G30770.1
MEMILSISLCLTTLITLLLLRRFLKRTATKVNLPPSPWRLPVIGNLHQLSLHPHRSLRSLSLRYGPLMLLHFGRVPILVVSSGEAAQEVLKTHDHKFANRPRSKAVHGLMNGGRDVVFAPYGEYWRQMKSVCILNLLTNKMVESFEKVREDEVNAMIEKLEKASSSSSSENLSELFITLPSDVTSRVALGRKHSEDETARDLKKRVRQIMELLGEFPIGEYVPILAWIDGIRGFNNKIKEVSRGFSDLMDKVVQEHLEASNDKADFVDILLSIEKDKNSGFQVQRNDIKFMILDMFIGGTSTTSTLLEWTMTELIRSPKSMKKLQDEIRSTIRPHGSYIKEKEVENMKYLKAVIKEVLRLHPSLPMILPRLLSEDVKVKGYNIAAGTEVIINAWAIQRDTAIWGPDAEEFKPERHLDSGLDYHGKNLNYIPFGSGRRICPGINLALGLAEVTVANLVGRFDWRVEAGPNGDQPDLTEAIGIDVCRKFPLIAFPSSVV