Gene Details:

• Gene ID: AT2G30750
• Gene Symbol: CYP71A12
• Gene Name: cytochrome P450, family 71, subfamily A, polypeptide 12
• Description: cytochrome P450 family 71 polypeptide;(source:Araport11)
• TAIR Accession:
• Genome: Araport11_genome_release
• Species: Arabidopsis thaliana

Transcripts:

• AT2G30750.1

Plant Ontology Annotations:

• PO:0009029  — stamen — estambre (Spanish, exact), 雄蕊 (Japanese, exact), Poaceae stamen (narrow), Zea stamen (narrow)

Germplasm Phenotype:

• CS72340  — reduced camalexin production
• GABI_127H03  — When camalexin was determined two days after infection with Pseudomonas syringae, no reduction in camalexin levels relative to wild-type plants was observed.
• cyp71a12/cyp71a13  — More susceptible to P. syringae compared to mature wildtype plants displaying age-related resistance; infiltration of exogenous DHCA enhanced resistance in mature.

Function-related keywords:

• stamen

Literature:

• SAGE analysis of transcriptome responses in Arabidopsis roots exposed to 2,4,6-trinitrotoluene.   DOI:  10.1104/pp.103.028019 ;  PMID:  14551330
• Camalexin is synthesized from indole-3-acetaldoxime, a key branching point between primary and secondary metabolism in Arabidopsis.   DOI:  10.1073/pnas.0305876101 ;  PMID:  15148388
• An inducible targeted tagging system for localized saturation mutagenesis in Arabidopsis.   DOI:  10.1104/pp.104.050633 ;  PMID:  15644463
• Gene expression changes in Arabidopsis thaliana seedling roots exposed to the munition hexahydro-1,3,5-trinitro-1,3,5-triazine.   DOI:  10.1021/es050385r ;  PMID:  16173598
• The association among gene expression responses to nine abiotic stress treatments in Arabidopsis thaliana.   DOI:  10.1534/genetics.106.061374 ;  PMID:  17028338
• Nonenzymatic lipid peroxidation reprograms gene expression and activates defense markers in Arabidopsis tocopherol-deficient mutants.   DOI:  10.1105/tpc.106.044065 ;  PMID:  17194769
• Oxylipins produced by the 9-lipoxygenase pathway in Arabidopsis regulate lateral root development and defense responses through a specific signaling cascade.   DOI:  10.1105/tpc.106.046052 ;  PMID:  17369372
• Developmental steps in acquiring competence for shoot development in Arabidopsis tissue culture.   DOI:  10.1007/s00425-007-0565-4 ;  PMID:  17581762
• Arabidopsis cytochrome P450 monooxygenase 71A13 catalyzes the conversion of indole-3-acetaldoxime in camalexin synthesis.   DOI:  10.1105/tpc.107.051383 ;  PMID:  17573535
• The Arabidopsis NFYA5 transcription factor is regulated transcriptionally and posttranscriptionally to promote drought resistance.   DOI:  10.1105/tpc.108.059444 ;  PMID:  18682547
• Identification and characterization of ANAC042, a transcription factor family gene involved in the regulation of camalexin biosynthesis in Arabidopsis.   DOI:  10.1094/MPMI-09-11-0244 ;  PMID:  22295908
• Arabidopsis acetyl-amido synthetase GH3.5 involvement in camalexin biosynthesis through conjugation of indole-3-carboxylic acid and cysteine and upregulation of camalexin biosynthesis genes.   DOI:  10.1111/j.1744-7909.2012.01131.x ;  PMID:  22624950
• Metabolic and transcriptomic changes induced in Arabidopsis by the rhizobacterium Pseudomonas fluorescens SS101.   DOI:  10.1104/pp.112.207324 ;  PMID:  23073694
• Iron-dependent modifications of the flower transcriptome, proteome, metabolome, and hormonal content in an Arabidopsis ferritin mutant.   DOI:  10.1093/jxb/ert112 ;  PMID:  23682113
• De novo genetic engineering of the camalexin biosynthetic pathway.   DOI:  10.1016/j.jbiotec.2013.06.013 ;  PMID:  23830903
• TRANSCRIPTION ACTIVATOR-LIKE EFFECTOR NUCLEASE-Mediated Generation and Metabolic Analysis of Camalexin-Deficient cyp71a12 cyp71a13 Double Knockout Lines.   DOI:  10.1104/pp.15.00481 ;  PMID:  25953104
• Camalexin contributes to the partial resistance of Arabidopsis thaliana to the biotrophic soilborne protist Plasmodiophora brassicae.   DOI:  10.3389/fpls.2015.00539 ;  PMID:  26257750
• A new cyanogenic metabolite in Arabidopsis required for inducible pathogen defence.   DOI:  10.1038/nature14907 ;  PMID:  26352477
• Dissection of the network of indolic defence compounds in Arabidopsis thaliana by multiple mutant analysis.   DOI:  10.1016/j.phytochem.2019.01.009 ;  PMID:  30798200
• Root-specific camalexin biosynthesis controls the plant growth-promoting effects of multiple bacterial strains.   DOI:  10.1073/pnas.1818604116 ;  PMID:  31311863
• The role of CYP71A12 monooxygenase in pathogen-triggered tryptophan metabolism and Arabidopsis immunity.   DOI:  10.1111/nph.16118 ;  PMID:  31411742
• The Formation of a Camalexin Biosynthetic Metabolon.   DOI:  10.1105/tpc.19.00403 ;  PMID:  31511315
• Tryptophan-derived metabolites and BAK1 separately contribute to Arabidopsis postinvasive immunity against Alternaria brassicicola.   DOI:  10.1038/s41598-020-79562-x ;  PMID:  33452278
• Metabolite profiling reveals a role for intercellular dihydrocamalexic acid in the response of mature Arabidopsis thaliana to Pseudomonas syringae.   DOI:  10.1016/j.phytochem.2021.112747 ;  PMID:  33823457
• Multiple indole glucosinolates and myrosinases defend Arabidopsis against Tetranychus urticae herbivory.   DOI:  10.1093/plphys/kiab247 ;  PMID:  34618148
• Priming of camalexin accumulation in induced systemic resistance by beneficial bacteria against Botrytis cinerea and Pseudomonas syringae pv. tomato DC3000.   DOI:  10.1093/jxb/erac070 ;  PMID:  35191984
• Shoot-root interaction in control of camalexin exudation in Arabidopsis.   DOI:  10.1093/jxb/erad031 ;  PMID:  36651631

Sequences: