Information report for AT2G30470
Gene Details
|
|
Functional Descriptions
- PO:0000037 — shoot axis apex — ápice del epiblasto (epiblastema) (Spanish, exact), シュート頂、茎頂 (Japanese, exact)
- PO:0008019 — leaf lamina base — base de la lámina de la hoja (Spanish, exact), 葉身基部 (Japanese, exact)
- PO:0009005 — root — raíz (Spanish, exact), radices (exact, plural), radix (exact), 根 (Japanese, exact), aerial root (narrow), climbing root (narrow)
- PO:0009006 — shoot system — sistema de epiblasto (epiblastema) (Spanish, exact), シュート系、苗条系 (Japanese, exact), Poaceae crown (related), shoot (related), thalli (related), thallus (related), tree crown (narrow)
- PO:0009009 — plant embryo — embrión (Spanish, exact), 植物胚 (Japanese, exact), germ (related), embryo (broad)
- PO:0009025 — vascular leaf — foliage leaf (exact), hoja vascular (Spanish, exact), leaf, vascular (exact), vascular leaves (exact, plural), 維管束のある葉, または維管束植物の葉 (Japanese, exact), crozier (related), macrophyll (related), megaphyll (related), ascidia (narrow), ascidium (narrow), fiddlehead (narrow), frond (narrow), needle-like leaf (narrow), pitcher (narrow), pitcher blade (narrow), pitcher-blade (narrow), scale-like leaf (narrow), sterile frond (narrow), trophophyll (narrow)
- PO:0009029 — stamen — estambre (Spanish, exact), 雄蕊 (Japanese, exact), Poaceae stamen (narrow), Zea stamen (narrow)
- PO:0009031 — sepal — sépalo (Spanish, exact), がく片 (Japanese, exact)
- PO:0009046 — flower — flor (Spanish, exact), 花 (Japanese, exact), floret (related), Asteraceae floret (narrow), basal flower (narrow), double flower (narrow), hermaphrodite flower (narrow), monoclinous flower (narrow), perfect flower (narrow)
- PO:0009052 — inflorescence flower pedicel — 小花柄 (Japanese, related), pedicelo (Spanish, broad)
- PO:0020030 — cotyledon — cotiledón (Spanish, exact), seed leaf (exact), 子葉 (Japanese, exact)
- PO:0020038 — petiole — pecíolo (Spanish, exact), 葉柄 (Japanese, exact)
- PO:0020100 — hypocotyl — hipocótile (Spanish, exact), 胚軸 (Japanese, exact)
- PO:0020137 — leaf apex — ápice de la hoja (Spanish, exact), 葉先 (Japanese, exact), leaf lamina apex (narrow), phyllid apex (narrow)
- PO:0025022 — collective leaf structure — estructura colectiva de hoja (Spanish, exact), leaf series (exact), 葉が集まった構造 (Japanese, exact), leaf whorl (narrow), rosette (narrow), cycle (broad), verticil (broad)
- PO:0025281 — pollen — polen (Spanish, exact), pollen grain (exact), 花粉 (Japanese, exact)
- PO:0009047 — stem — caña (Spanish, exact), culm (exact), eje primario (Spanish, exact), primary axis (exact), primary stem (exact), tallo (Spanish, exact), tronco (Spanish, exact), 茎 (Japanese, exact), bole (narrow), cane (narrow), caudex (narrow), caudices (narrow), core (narrow), primocane (narrow), scape (narrow), stalk (narrow), trunk (narrow)
- PO:0000084 — plant sperm cell — célula espermática o esperma (Spanish, exact), male gamete (exact), microgamete (exact), 植物精子細胞 (Japanese, exact), sperm nucleus (related), sperm cell (broad)
- CS72451 — Delayed vegetative phase change (abaxial trichomes ~leaf 9 in LD, increased leaf blade base angle and decreased blade length:width ration for leaves 3 and 5) and flowering time (~17 leaves in LD).
- CS72452 — Delayed vegetative phase change (abaxial trichomes ~leaf 10 in LD, increased leaf blade base angle and decreased blade length:width ration for leaves 3 and 5) and flowering time (~19 leaves in LD).
- CS72453 — Delayed vegetative phase change (abaxial trichomes ~leaf 9 in LD, increased leaf blade base angle and decreased blade length:width ration for leaves 3 and 5) and flowering time (~13 leaves in LD).
- CS72454 — mi156ac mir157ac phenotype is largely epistatic to val1-2; accelerated vegetative phase change; mir156ac mir157ac precocious leaf shape phenotype partially suppressed
- CS72455 — GUS accumulation in provasculature during embryogenesis, and shoot, root and lateral root primordia meristems and young leaf tissue following germination; rescues val1-2 vegetative change phenotype
- val1 val2 — Somatic embryonic phenotypes; impaired PRC2 recruitment; genome-wide changes in the distribution of H3K27me3.
Functional Keywords
- shoot axis apex , leaf lamina base , root , shoot system , plant embryo , vascular leaf , stamen , sepal , flower , inflorescence flower pedicel , cotyledon , petiole , hypocotyl , leaf apex , collective leaf structure , pollen , root , vascular leaf , flower , stem , plant sperm cell
Literature and News
- Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes. DOI: 10.1126/science.290.5499.2105 ; PMID: 11118137
- Ten members of the Arabidopsis gene family encoding methyl-CpG-binding domain proteins are transcriptionally active and at least one, AtMBD11, is crucial for normal development. DOI: 10.1093/nar/gkg735 ; PMID: 12954765
- Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins. DOI: 10.1105/tpc.016055 ; PMID: 14671022
- Analysis of a sugar response mutant of Arabidopsis identified a novel B3 domain protein that functions as an active transcriptional repressor. DOI: 10.1104/pp.104.057752 ; PMID: 15894743
- Response diversity of Arabidopsis thaliana ecotypes in elevated [CO2] in the field. DOI: 10.1007/s11103-006-9041-y ; PMID: 16941220
- Repression of the LEAFY COTYLEDON 1/B3 regulatory network in plant embryo development by VP1/ABSCISIC ACID INSENSITIVE 3-LIKE B3 genes. DOI: 10.1104/pp.106.092320 ; PMID: 17158584
- A novel HSI2 mutation in Arabidopsis affects the PHD-like domain and leads to derepression of seed-specific gene expression. DOI: 10.1007/s00425-012-1630-1 ; PMID: 22476218
- Identification of direct targets of FUSCA3, a key regulator of Arabidopsis seed development. DOI: 10.1104/pp.112.212282 ; PMID: 23314941
- Acyl-lipid metabolism. DOI: 10.1199/tab.0161 ; PMID: 23505340
- Distinct roles of LAFL network genes in promoting the embryonic seedling fate in the absence of VAL repression. DOI: 10.1104/pp.113.220988 ; PMID: 24043445
- High-level expression of sugar inducible gene2 (HSI2) is a negative regulator of drought stress tolerance in Arabidopsis. DOI: 10.1186/1471-2229-13-170 ; PMID: 24168327
- HSI2/VAL1 PHD-like domain promotes H3K27 trimethylation to repress the expression of seed maturation genes and complex transgenes in Arabidopsis seedlings. DOI: 10.1186/s12870-014-0293-4 ; PMID: 25367506
- Potential targets of VIVIPAROUS1/ABI3-LIKE1 (VAL1) repression in developing Arabidopsis thaliana embryos. DOI: 10.1111/tpj.13106 ; PMID: 26678037
- HSI2 Repressor Recruits MED13 and HDA6 to Down-Regulate Seed Maturation Gene Expression Directly During Arabidopsis Early Seedling Growth. DOI: 10.1093/pcp/pcw095 ; PMID: 27335347
- Arabidopsis transcriptional repressor VAL1 triggers Polycomb silencing at FLC during vernalization. DOI: 10.1126/science.aaf7354 ; PMID: 27471304
- A cis cold memory element and a trans epigenome reader mediate Polycomb silencing of FLC by vernalization in Arabidopsis. DOI: 10.1038/ng.3712 ; PMID: 27819666
- The Arabidopsis Polycomb Repressive Complex 1 (PRC1) Components AtBMI1A, B, and C Impact Gene Networks throughout All Stages of Plant Development. DOI: 10.1104/pp.16.01259 ; PMID: 27837089
- A DNA element that remembers winter. DOI: 10.1038/ng.3727 ; PMID: 27898079
- HSI2/VAL1 Silences AGL15 to Regulate the Developmental Transition from Seed Maturation to Vegetative Growth in Arabidopsis. DOI: 10.1105/tpc.17.00655 ; PMID: 29475938
- Structural basis of DNA target recognition by the B3 domain of Arabidopsis epigenome reader VAL1. DOI: 10.1093/nar/gky256 ; PMID: 29660015
- Structural insight into the role of VAL1 B3 domain for targeting to FLC locus in Arabidopsis thaliana. DOI: 10.1016/j.bbrc.2018.05.002 ; PMID: 29733847
- DNA recognition by Arabidopsis transcription factors ABI3 and NGA1. DOI: 10.1111/febs.14649 ; PMID: 30183137
- Embryonic resetting of the parental vernalized state by two B3 domain transcription factors in Arabidopsis. DOI: 10.1038/s41477-019-0402-3 ; PMID: 30962525
- The B3-Domain Transcription Factor VAL1 Regulates the Floral Transition by Repressing FLOWERING LOCUS T. DOI: 10.1104/pp.19.00642 ; PMID: 31289216
- HISTONE DEACETYLASE 9 Functions with Polycomb Silencing to Repress FLOWERING LOCUS C Expression. DOI: 10.1104/pp.19.00793 ; PMID: 31641076
- HSI2/VAL1 and HSL1/VAL2 function redundantly to repress DOG1 expression in Arabidopsis seeds and seedlings. DOI: 10.1111/nph.16559 ; PMID: 32201955
- The transcriptional repressors VAL1 and VAL2 recruit PRC2 for genome-wide Polycomb silencing in Arabidopsis. DOI: 10.1093/nar/gkaa1129 ; PMID: 33270882
- Brassinosteroids repress the seed maturation program during the seed-to-seedling transition. DOI: 10.1093/plphys/kiab089 ; PMID: 33620498
- EAR domain-containing transcription factors trigger PRC2-mediated chromatin marking in Arabidopsis. DOI: 10.1093/plcell/koab139 ; PMID: 34003929
- Interaction Analysis between the Arabidopsis Transcription Repressor VAL1 and Transcription Coregulators SIN3-LIKEs (SNLs). DOI: 10.3390/ijms23136987 ; PMID: 35805982
- The transcriptional repressors VAL1 and VAL2 mediate genome-wide recruitment of the CHD3 chromatin remodeler PICKLE in Arabidopsis. DOI: 10.1093/plcell/koac217 ; PMID: 35866997
- VAL1 acts as an assembly platform co-ordinating co-transcriptional repression and chromatin regulation at Arabidopsis FLC. DOI: 10.1038/s41467-022-32897-7 ; PMID: 36130923
- Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes. DOI: 10.1126/science.290.5499.2105 ; PMID: 11118137
- Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins. DOI: 10.1105/tpc.016055 ; PMID: 14671022
- Two B3 domain transcriptional repressors prevent sugar-inducible expression of seed maturation genes in Arabidopsis seedlings. DOI: 10.1073/pnas.0607940104 ; PMID: 17267611
Gene Resources
Homologs
- Brassica napus GSBRNA2T00113430001, GSBRNA2T00142144001, GSBRNA2T00048551001, GSBRNA2T00024513001, GSBRNA2T00105140001
- Brassica oleracea XP_013630357.1, XP_013636700.1, XP_013636699.1, XP_013636698.1, XP_013633557.1
- Brassica rapa XP_009132737.1, XP_009144302.1, XP_009141065.1
- Raphanus raphanistrum RrC4353_p1
Sequences
cDNA Sequence
- >AT2G30470.1
ATTTCTATATATATTATATACCAAAAAAACATATCTTAACAAAGTCAAAAAAAAACCAAAGTCTTTCACTTTGTGTCTGTTCTAAATCTCTGCGAGTTTTCTTACTTTTCGAGTTTTGTGTGTGTCTTCAAGTGTCGTGCATGCATTTTATGCGTTTCGTTCACTTGCATGCTCTCTCCCTCTTTCTCTCTCTATCTCACCCATAAAAGTTTTAATTTTTCACATCGATAAATTAAATTGAAACAAAAAAAAAAATTCACCCAAAAAAAAAAAACCTCGTTGCCTTCTTCTTCGCCGTTACAGTCCTCTTTCTTTCTTCAATTCGCCGTCAAAATCTTCTCTTTCTCTTCCCCCGCCGGTCCTTCACCAATCCTCTGATCTCTCTACACACGAACCTTTGATTTTGACCAACGTCGATGCATGTTCATGACTAGTCTCTTCCTCAATCCTTCAATTTCATCAATTCACGTCGATTTCGTATCCGATTCGTTGTTCTAGCTCTTTGTGTGGTGTTAGGGTTTTAAGATTTTGGAATTGGGGTTTGGAGTTTGTGATGTTTGAAGTCAAAATGGGGTCAAAGATGTGCATGAACGCTTCATGTGGTACGACTTCTACTGTTGAATGGAAGAAAGGTTGGCCTCTTCGATCTGGTCTTCTCGCTGATCTCTGTTATCGTTGCGGATCTGCGTATGAGAGTTCTCTATTCTGTGAACAATTTCATAAGGACCAATCTGGTTGGAGGGAATGCTATTTGTGTAGCAAGAGACTACATTGTGGATGCATTGCTTCTAAGGTAACGATTGAGTTAATGGACTATGGTGGTGTTGGTTGTAGTACATGTGCTTGCTGCCATCAACTCAATTTGAACACAAGGGGTGAGAATCCAGGTGTTTTTAGCAGATTGCCAATGAAAACGTTAGCTGATAGGCAACATGTAAATGGCGAAAGCGGAGGAAGAAACGAAGGCGATCTCTTTTCTCAGCCACTAGTCATGGGCGGAGATAAAAGGGAAGAGTTCATGCCTCACCGTGGGTTTGGTAAGCTAATGAGTCCAGAAAGTACAACCACCGGGCATAGGCTGGATGCTGCTGGGGAAATGCATGAATCATCACCTTTACAGCCATCTTTAAATATGGGTTTGGCTGTGAATCCGTTTAGCCCATCTTTTGCAACCGAGGCTGTCGAGGGAATGAAACACATCAGTCCTTCTCAGTCCAACATGGTCCATTGCTCTGCTTCTAATATACTGCAAAAGCCATCAAGACCTGCTATTTCAACTCCTCCTGTGGCTAGTAAATCCGCTCAGGCGCGGATTGGAAGGCCTCCTGTCGAAGGGCGAGGGAGAGGCCACTTGCTTCCGCGGTATTGGCCAAAATATACGGATAAAGAGGTTCAGCAGATCTCTGGAAATTTGAATTTGAACATTGTACCTCTCTTTGAGAAAACTCTTAGTGCCAGTGATGCTGGTCGCATTGGTCGTCTAGTTCTTCCAAAAGCCTGTGCAGAGGCATATTTTCCTCCGATTAGTCAATCCGAAGGCATTCCTTTGAAAATCCAAGATGTGAGGGGTAGGGAGTGGACGTTCCAGTTCAGATATTGGCCCAATAACAATAGTAGAATGTATGTTTTAGAAGGTGTCACTCCATGCATACAGTCCATGATGCTACAGGCTGGTGATACAGTAACTTTCAGTCGGGTTGATCCTGGCGGAAAACTAATCATGGGTTCCAGGAAGGCAGCTAATGCTGGAGACATGCAGGGTTGTGGGCTCACCAACGGAACATCAACTGAGGACACATCATCGTCTGGTGTAACAGAAAACCCACCCTCCATAAATGGTTCCTCGTGTATTTCACTAATACCGAAAGAGTTGAATGGTATGCCTGAGAATTTGAACAGTGAGACTAACGGGGGCAGGATAGGTGATGATCCTACACGAGTTAAAGAGAAGAAGAGAACTCGAACCATTGGTGCAAAAAATAAGAGACTTCTTTTGCATAGTGAAGAATCTATGGAGCTGAGACTCACTTGGGAAGAAGCTCAGGACTTGCTTCGTCCCTCTCCTAGTGTAAAGCCTACCATCGTTGTCATTGAGGAGCAAGAAATTGAAGAATATGACGAACCTCCTGTCTTTGGAAAGAGGACTATAGTCACTACAAAACCTTCAGGTGAACAGGAACGATGGGCAACTTGCGACGACTGCTCTAAATGGAGAAGGTTACCTGTAGATGCTCTTCTTTCCTTTAAATGGACATGTATAGACAATGTTTGGGATGTGAGTAGGTGTTCATGTTCTGCACCGGAGGAGAGTCTGAAGGAACTTGAGAATGTTCTTAAAGTAGGAAGAGAGCACAAGAAGAGAAGAACTGGGGAAAGCCAGGCAGCAAAAAGTCAGCAAGAACCGTGTGGTTTGGACGCACTGGCGAGTGCAGCAGTCTTAGGAGACACAATAGGCGAGCCAGAGGTAGCGACCACGACCAGACATCCAAGGCACAGGGCTGGATGCTCTTGCATCGTGTGCATTCAGCCACCAAGTGGGAAAGGTAGGCACAAGCCTACATGTGGCTGCACTGTGTGTAGCACCGTGAAGAGAAGGTTCAAGACGCTTATGATGAGGAGGAAGAAGAAGCAGTTGGAGCGCGATGTAACAGCAGCAGAAGATAAGAAGAAGAAGGACATGGAACTGGCTGAGTCTGATAAGAGTAAGGAGGAGAAGGAAGTGAACACAGCGAGAATAGACCTGAACAGTGATCCATACAATAAAGAAGATGTTGAAGCTGTTGCGGTGGAGAAAGAAGAGAGTCGAAAAAGAGCAATAGGACAGTGTTCGGGCGTGGTGGCTCAAGACGCCAGTGATGTTTTAGGAGTTACAGAGTTAGAAGGAGAGGGTAAGAATGTTCGTGAAGAGCCGAGAGTTTCAAGCTGATATGGAAGGAAAAAGGGAAAGGGTAAAAGCCAAAGTCATAGCCAGTTTTATTAATATGCTGAGACCAAGAGTAGGAGAAGAAGAAGAGAAAGAGAGAGAGAGAGAGAGAGAGAGAAGTACAGTTTTGTGTTTGATTCTGTCATAGTTGTAGGAAAAATAAGTTTCTGGTTCTAAACAGCGACAATGTCCCATCTTTTGTTTTTTGTTTTTGTTTTTGTATTTTTATGGTATCGTGTTGAGTTTGGGGTTTATAGTATGTCTCCATTAATCTAGGTTTTGTTGTAGAAGGCAAATGGAGCTTTGTGCTTGGTGATGAAACAGTTGAGTTGATTTTTTTTTTTGTAATTGTTTTCAACCAAATGCCTAGTTGGTTTAATTTTTTTAAAAGTTGTTTCTTATAATATTGTTAAACACAAATTATGACAGTTGTTGAAAACTGCATGAAGTAGACTTGTAAATGGTATAAGGAGATTAAT
CDS Sequence
- >AT2G30470.1
ATGTTTGAAGTCAAAATGGGGTCAAAGATGTGCATGAACGCTTCATGTGGTACGACTTCTACTGTTGAATGGAAGAAAGGTTGGCCTCTTCGATCTGGTCTTCTCGCTGATCTCTGTTATCGTTGCGGATCTGCGTATGAGAGTTCTCTATTCTGTGAACAATTTCATAAGGACCAATCTGGTTGGAGGGAATGCTATTTGTGTAGCAAGAGACTACATTGTGGATGCATTGCTTCTAAGGTAACGATTGAGTTAATGGACTATGGTGGTGTTGGTTGTAGTACATGTGCTTGCTGCCATCAACTCAATTTGAACACAAGGGGTGAGAATCCAGGTGTTTTTAGCAGATTGCCAATGAAAACGTTAGCTGATAGGCAACATGTAAATGGCGAAAGCGGAGGAAGAAACGAAGGCGATCTCTTTTCTCAGCCACTAGTCATGGGCGGAGATAAAAGGGAAGAGTTCATGCCTCACCGTGGGTTTGGTAAGCTAATGAGTCCAGAAAGTACAACCACCGGGCATAGGCTGGATGCTGCTGGGGAAATGCATGAATCATCACCTTTACAGCCATCTTTAAATATGGGTTTGGCTGTGAATCCGTTTAGCCCATCTTTTGCAACCGAGGCTGTCGAGGGAATGAAACACATCAGTCCTTCTCAGTCCAACATGGTCCATTGCTCTGCTTCTAATATACTGCAAAAGCCATCAAGACCTGCTATTTCAACTCCTCCTGTGGCTAGTAAATCCGCTCAGGCGCGGATTGGAAGGCCTCCTGTCGAAGGGCGAGGGAGAGGCCACTTGCTTCCGCGGTATTGGCCAAAATATACGGATAAAGAGGTTCAGCAGATCTCTGGAAATTTGAATTTGAACATTGTACCTCTCTTTGAGAAAACTCTTAGTGCCAGTGATGCTGGTCGCATTGGTCGTCTAGTTCTTCCAAAAGCCTGTGCAGAGGCATATTTTCCTCCGATTAGTCAATCCGAAGGCATTCCTTTGAAAATCCAAGATGTGAGGGGTAGGGAGTGGACGTTCCAGTTCAGATATTGGCCCAATAACAATAGTAGAATGTATGTTTTAGAAGGTGTCACTCCATGCATACAGTCCATGATGCTACAGGCTGGTGATACAGTAACTTTCAGTCGGGTTGATCCTGGCGGAAAACTAATCATGGGTTCCAGGAAGGCAGCTAATGCTGGAGACATGCAGGGTTGTGGGCTCACCAACGGAACATCAACTGAGGACACATCATCGTCTGGTGTAACAGAAAACCCACCCTCCATAAATGGTTCCTCGTGTATTTCACTAATACCGAAAGAGTTGAATGGTATGCCTGAGAATTTGAACAGTGAGACTAACGGGGGCAGGATAGGTGATGATCCTACACGAGTTAAAGAGAAGAAGAGAACTCGAACCATTGGTGCAAAAAATAAGAGACTTCTTTTGCATAGTGAAGAATCTATGGAGCTGAGACTCACTTGGGAAGAAGCTCAGGACTTGCTTCGTCCCTCTCCTAGTGTAAAGCCTACCATCGTTGTCATTGAGGAGCAAGAAATTGAAGAATATGACGAACCTCCTGTCTTTGGAAAGAGGACTATAGTCACTACAAAACCTTCAGGTGAACAGGAACGATGGGCAACTTGCGACGACTGCTCTAAATGGAGAAGGTTACCTGTAGATGCTCTTCTTTCCTTTAAATGGACATGTATAGACAATGTTTGGGATGTGAGTAGGTGTTCATGTTCTGCACCGGAGGAGAGTCTGAAGGAACTTGAGAATGTTCTTAAAGTAGGAAGAGAGCACAAGAAGAGAAGAACTGGGGAAAGCCAGGCAGCAAAAAGTCAGCAAGAACCGTGTGGTTTGGACGCACTGGCGAGTGCAGCAGTCTTAGGAGACACAATAGGCGAGCCAGAGGTAGCGACCACGACCAGACATCCAAGGCACAGGGCTGGATGCTCTTGCATCGTGTGCATTCAGCCACCAAGTGGGAAAGGTAGGCACAAGCCTACATGTGGCTGCACTGTGTGTAGCACCGTGAAGAGAAGGTTCAAGACGCTTATGATGAGGAGGAAGAAGAAGCAGTTGGAGCGCGATGTAACAGCAGCAGAAGATAAGAAGAAGAAGGACATGGAACTGGCTGAGTCTGATAAGAGTAAGGAGGAGAAGGAAGTGAACACAGCGAGAATAGACCTGAACAGTGATCCATACAATAAAGAAGATGTTGAAGCTGTTGCGGTGGAGAAAGAAGAGAGTCGAAAAAGAGCAATAGGACAGTGTTCGGGCGTGGTGGCTCAAGACGCCAGTGATGTTTTAGGAGTTACAGAGTTAGAAGGAGAGGGTAAGAATGTTCGTGAAGAGCCGAGAGTTTCAAGCTGA
Protein Sequence
- >AT2G30470.1
MFEVKMGSKMCMNASCGTTSTVEWKKGWPLRSGLLADLCYRCGSAYESSLFCEQFHKDQSGWRECYLCSKRLHCGCIASKVTIELMDYGGVGCSTCACCHQLNLNTRGENPGVFSRLPMKTLADRQHVNGESGGRNEGDLFSQPLVMGGDKREEFMPHRGFGKLMSPESTTTGHRLDAAGEMHESSPLQPSLNMGLAVNPFSPSFATEAVEGMKHISPSQSNMVHCSASNILQKPSRPAISTPPVASKSAQARIGRPPVEGRGRGHLLPRYWPKYTDKEVQQISGNLNLNIVPLFEKTLSASDAGRIGRLVLPKACAEAYFPPISQSEGIPLKIQDVRGREWTFQFRYWPNNNSRMYVLEGVTPCIQSMMLQAGDTVTFSRVDPGGKLIMGSRKAANAGDMQGCGLTNGTSTEDTSSSGVTENPPSINGSSCISLIPKELNGMPENLNSETNGGRIGDDPTRVKEKKRTRTIGAKNKRLLLHSEESMELRLTWEEAQDLLRPSPSVKPTIVVIEEQEIEEYDEPPVFGKRTIVTTKPSGEQERWATCDDCSKWRRLPVDALLSFKWTCIDNVWDVSRCSCSAPEESLKELENVLKVGREHKKRRTGESQAAKSQQEPCGLDALASAAVLGDTIGEPEVATTTRHPRHRAGCSCIVCIQPPSGKGRHKPTCGCTVCSTVKRRFKTLMMRRKKKQLERDVTAAEDKKKKDMELAESDKSKEEKEVNTARIDLNSDPYNKEDVEAVAVEKEESRKRAIGQCSGVVAQDASDVLGVTELEGEGKNVREEPRVSS