Gene Details:

• Gene ID: AT2G30280
• Gene Symbol: DMS4, RDM4
• Gene Name: DEFECTIVE IN MERISTEM SILENCING 4, RNA-directed DNA methylation 4
• Description: RNA-directed DNA methylation 4;(source:Araport11)
• TAIR Accession: locus:2065764
• Genome: Araport11_genome_release
• Species: Arabidopsis thaliana

Transcripts:

• AT2G30280.1

Plant Ontology Annotations:

• PO:0000037  — shoot axis apex — ápice del epiblasto (epiblastema) (Spanish, exact), シュート頂、茎頂 (Japanese, exact)
• PO:0008019  — leaf lamina base — base de la lámina de la hoja (Spanish, exact), 葉身基部 (Japanese, exact)
• PO:0009005  — root — raíz (Spanish, exact), radices (exact, plural), radix (exact), 根 (Japanese, exact), aerial root (narrow), climbing root (narrow)
• PO:0009006  — shoot system — sistema de epiblasto (epiblastema) (Spanish, exact), シュート系、苗条系 (Japanese, exact), Poaceae crown (related), shoot (related), thalli (related), thallus (related), tree crown (narrow)
• PO:0009009  — plant embryo — embrión (Spanish, exact), 植物胚 (Japanese, exact), germ (related), embryo (broad)
• PO:0009025  — vascular leaf — foliage leaf (exact), hoja vascular (Spanish, exact), leaf, vascular (exact), vascular leaves (exact, plural), 維管束のある葉, または維管束植物の葉 (Japanese, exact), crozier (related), macrophyll (related), megaphyll (related), ascidia (narrow), ascidium (narrow), fiddlehead (narrow), frond (narrow), needle-like leaf (narrow), pitcher (narrow), pitcher blade (narrow), pitcher-blade (narrow), scale-like leaf (narrow), sterile frond (narrow), trophophyll (narrow)
• PO:0009029  — stamen — estambre (Spanish, exact), 雄蕊 (Japanese, exact), Poaceae stamen (narrow), Zea stamen (narrow)
• PO:0009031  — sepal — sépalo (Spanish, exact), がく片 (Japanese, exact)
• PO:0009046  — flower — flor (Spanish, exact), 花 (Japanese, exact), floret (related), Asteraceae floret (narrow), basal flower (narrow), double flower (narrow), hermaphrodite flower (narrow), monoclinous flower (narrow), perfect flower (narrow)
• PO:0009052  — inflorescence flower pedicel — 小花柄 (Japanese, related), pedicelo (Spanish, broad)
• PO:0020030  — cotyledon — cotiledón (Spanish, exact), seed leaf (exact), 子葉 (Japanese, exact)
• PO:0020038  — petiole — pecíolo (Spanish, exact), 葉柄 (Japanese, exact)
• PO:0020100  — hypocotyl — hipocótile (Spanish, exact), 胚軸 (Japanese, exact)
• PO:0020137  — leaf apex — ápice de la hoja (Spanish, exact), 葉先 (Japanese, exact), leaf lamina apex (narrow), phyllid apex (narrow)
• PO:0025022  — collective leaf structure — estructura colectiva de hoja (Spanish, exact), leaf series (exact), 葉が集まった構造 (Japanese, exact), leaf whorl (narrow), rosette (narrow), cycle (broad), verticil (broad)
• PO:0025281  — pollen — polen (Spanish, exact), pollen grain (exact), 花粉 (Japanese, exact)
• PO:0000084  — plant sperm cell — célula espermática o esperma (Spanish, exact), male gamete (exact), microgamete (exact), 植物精子細胞 (Japanese, exact), sperm nucleus (related), sperm cell (broad)

Gene Ontology:

• GO:0006355  — acts upstream of or within — regulation of DNA-templated transcription
• GO:0006306  — acts upstream of or within — DNA methylation
• GO:0009791  — acts upstream of or within — post-embryonic development
• GO:0005634  — located in — nucleus
• GO:0003700  — enables — DNA-binding transcription factor activity
• GO:0032502  — acts upstream of or within — developmental process

Germplasm Phenotype:

• CS69178  — Floral inflorescences are more closely packed, short internode distances and disturbed phyllotaxy. Seedlings are pale and grow more slowly than wildtype seedlings, late flowering.
• dms4-1  — Mutants displays defects in plant development and RNA-directed DNA methylation. Floral inflorescences of mutant plants are more closely packed than those of wild type. Mutant seedlings are pale and grow slowly. Short internode distances and disturbed phyllotaxy.

Function-related keywords:

• shoot axis apex ,  leaf lamina base ,  root ,  shoot system ,  plant embryo ,  vascular leaf ,  stamen ,  sepal ,  flower ,  inflorescence flower pedicel ,  cotyledon ,  petiole ,  hypocotyl ,  leaf apex ,  collective leaf structure ,  pollen ,  plant sperm cell

Literature:

• Global analysis of Arabidopsis gene expression uncovers a complex array of changes impacting pathogen response and cell cycle during geminivirus infection.   DOI:  10.1104/pp.108.121038 ;  PMID:  18650403
• A conserved transcriptional regulator is required for RNA-directed DNA methylation and plant development.   DOI:  10.1101/gad.1851809 ;  PMID:  19903758
• RNA-directed DNA methylation and plant development require an IWR1-type transcription factor.   DOI:  10.1038/embor.2009.246 ;  PMID:  20010803
• Arabidopsis female gametophyte gene expression map reveals similarities between plant and animal gametes.   DOI:  10.1016/j.cub.2010.01.051 ;  PMID:  20226671
• SHH1, a homeodomain protein required for DNA methylation, as well as RDR2, RDM4, and chromatin remodeling factors, associate with RNA polymerase IV.   DOI:  10.1371/journal.pgen.1002195 ;  PMID:  21811420
• RNA polymerase V-dependent small RNAs in Arabidopsis originate from small, intergenic loci including most SINE repeats.   DOI:  10.4161/epi.20290 ;  PMID:  22647529
• Comprehensive analysis of silencing mutants reveals complex regulation of the Arabidopsis methylome.   DOI:  10.1016/j.cell.2012.10.054 ;  PMID:  23313553
• RDM4 modulates cold stress resistance in Arabidopsis partially through the CBF-mediated pathway.   DOI:  10.1111/nph.13727 ;  PMID:  26522658

Sequences: