Gene Details:

• Gene ID: AT2G28520
• Gene Symbol: VHA-A1
• Gene Name: vacuolar proton ATPase A1
• Description: vacuolar proton ATPase A1;(source:Araport11)
• TAIR Accession: locus:2056598
• Genome: Araport11_genome_release
• Species: Arabidopsis thaliana

Transcripts:

• AT2G28520.1

Plant Ontology Annotations:

• PO:0000037  — shoot axis apex — ápice del epiblasto (epiblastema) (Spanish, exact), シュート頂、茎頂 (Japanese, exact)
• PO:0008019  — leaf lamina base — base de la lámina de la hoja (Spanish, exact), 葉身基部 (Japanese, exact)
• PO:0009005  — root — raíz (Spanish, exact), radices (exact, plural), radix (exact), 根 (Japanese, exact), aerial root (narrow), climbing root (narrow)
• PO:0009006  — shoot system — sistema de epiblasto (epiblastema) (Spanish, exact), シュート系、苗条系 (Japanese, exact), Poaceae crown (related), shoot (related), thalli (related), thallus (related), tree crown (narrow)
• PO:0009009  — plant embryo — embrión (Spanish, exact), 植物胚 (Japanese, exact), germ (related), embryo (broad)
• PO:0009025  — vascular leaf — foliage leaf (exact), hoja vascular (Spanish, exact), leaf, vascular (exact), vascular leaves (exact, plural), 維管束のある葉, または維管束植物の葉 (Japanese, exact), crozier (related), macrophyll (related), megaphyll (related), ascidia (narrow), ascidium (narrow), fiddlehead (narrow), frond (narrow), needle-like leaf (narrow), pitcher (narrow), pitcher blade (narrow), pitcher-blade (narrow), scale-like leaf (narrow), sterile frond (narrow), trophophyll (narrow)
• PO:0009029  — stamen — estambre (Spanish, exact), 雄蕊 (Japanese, exact), Poaceae stamen (narrow), Zea stamen (narrow)
• PO:0009031  — sepal — sépalo (Spanish, exact), がく片 (Japanese, exact)
• PO:0009046  — flower — flor (Spanish, exact), 花 (Japanese, exact), floret (related), Asteraceae floret (narrow), basal flower (narrow), double flower (narrow), hermaphrodite flower (narrow), monoclinous flower (narrow), perfect flower (narrow)
• PO:0009052  — inflorescence flower pedicel — 小花柄 (Japanese, related), pedicelo (Spanish, broad)
• PO:0020030  — cotyledon — cotiledón (Spanish, exact), seed leaf (exact), 子葉 (Japanese, exact)
• PO:0020038  — petiole — pecíolo (Spanish, exact), 葉柄 (Japanese, exact)
• PO:0020100  — hypocotyl — hipocótile (Spanish, exact), 胚軸 (Japanese, exact)
• PO:0020137  — leaf apex — ápice de la hoja (Spanish, exact), 葉先 (Japanese, exact), leaf lamina apex (narrow), phyllid apex (narrow)
• PO:0025022  — collective leaf structure — estructura colectiva de hoja (Spanish, exact), leaf series (exact), 葉が集まった構造 (Japanese, exact), leaf whorl (narrow), rosette (narrow), cycle (broad), verticil (broad)
• PO:0025281  — pollen — polen (Spanish, exact), pollen grain (exact), 花粉 (Japanese, exact)
• PO:0000084  — plant sperm cell — célula espermática o esperma (Spanish, exact), male gamete (exact), microgamete (exact), 植物精子細胞 (Japanese, exact), sperm nucleus (related), sperm cell (broad)
• PO:0025195  — pollen tube cell — célula del tubo polínico (Spanish, exact), 花粉管細胞 (Japanese, exact)

Gene Ontology:

• GO:0005794  — located in — Golgi apparatus
• GO:0012510  — located in — trans-Golgi network transport vesicle membrane
• GO:0005773  — located in — vacuole
• GO:0007035  — involved in — vacuolar acidification
• GO:0005737  — located in — cytoplasm
• GO:0005802  — located in — trans-Golgi network
• GO:0051117  — enables — ATPase binding
• GO:0032588  — located in — trans-Golgi network membrane
• GO:0016887  — enables — ATP hydrolysis activity
• GO:0000220  — part of — vacuolar proton-transporting V-type ATPase, V0 domain
• GO:0005768  — located in — endosome
• GO:0016471  — part of — vacuolar proton-transporting V-type ATPase complex
• GO:0046961  — enables — proton-transporting ATPase activity, rotational mechanism

Function-related keywords:

• shoot axis apex ,  leaf lamina base ,  root ,  shoot system ,  plant embryo ,  vascular leaf ,  stamen ,  sepal ,  flower ,  inflorescence flower pedicel ,  cotyledon ,  petiole ,  hypocotyl ,  leaf apex ,  collective leaf structure ,  pollen ,  plant sperm cell ,  pollen tube cell

Literature:

• A simple nomenclature for a complex proton pump: VHA genes encode the vacuolar H(+)-ATPase.   DOI:  10.1016/s1360-1385(02)02240-9 ;  PMID:  11950611
• Expression of an evolutionarily distinct novel BiP gene during the unfolded protein response in Arabidopsis thaliana.   DOI:  10.1016/s0378-1119(03)00559-6 ;  PMID:  12853141
• Isolation of intact vacuoles and proteomic analysis of tonoplast from suspension-cultured cells of Arabidopsis thaliana.   DOI:  10.1093/pcp/pch099 ;  PMID:  15215502
• Subcellular distribution of the V-ATPase complex in plant cells, and in vivo localisation of the 100 kDa subunit VHA-a within the complex.   DOI:  10.1186/1471-2121-5-29 ;  PMID:  15310389
• Vacuolar H+-ATPase activity is required for endocytic and secretory trafficking in Arabidopsis.   DOI:  10.1105/tpc.105.037978 ;  PMID:  16461582
• Mapping the Arabidopsis organelle proteome.   DOI:  10.1073/pnas.0506958103 ;  PMID:  16618929
• Transcriptome analyses show changes in gene expression to accompany pollen germination and tube growth in Arabidopsis.   DOI:  10.1104/pp.108.126375 ;  PMID:  18775970
• Pausing of Golgi bodies on microtubules regulates secretion of cellulose synthase complexes in Arabidopsis.   DOI:  10.1105/tpc.108.065334 ;  PMID:  19376932
• Conserved Arabidopsis ECHIDNA protein mediates trans-Golgi-network trafficking and cell elongation.   DOI:  10.1073/pnas.1018371108 ;  PMID:  21512130
• A membrane microdomain-associated protein, Arabidopsis Flot1, is involved in a clathrin-independent endocytic pathway and is required for seedling development.   DOI:  10.1105/tpc.112.095695 ;  PMID:  22589463
• Rab-A1c GTPase defines a population of the trans-Golgi network that is sensitive to endosidin1 during cytokinesis in Arabidopsis.   DOI:  10.1093/mp/sss116 ;  PMID:  23075992
• CONTINUOUS VASCULAR RING (COV1) is a trans-Golgi network-localized membrane protein required for Golgi morphology and vacuolar protein sorting.   DOI:  10.1093/pcp/pct195 ;  PMID:  24363287
• Label-free protein quantification for plant Golgi protein localization and abundance.   DOI:  10.1104/pp.114.245589 ;  PMID:  25122472
• Endogenous Arabidopsis messenger RNAs transported to distant tissues.   DOI:  10.1038/nplants.2015.25 ;  PMID:  27247031
• Nonselective Chemical Inhibition of Sec7 Domain-Containing ARF GTPase Exchange Factors.   DOI:  10.1105/tpc.18.00145 ;  PMID:  30018157
• The Inhibitor Endosidin 4 Targets SEC7 Domain-Type ARF GTPase Exchange Factors and Interferes with Subcellular Trafficking in Eukaryotes.   DOI:  10.1105/tpc.18.00127 ;  PMID:  30018156
• Involvement of BIG5 and BIG3 in BRI1 Trafficking Reveals Diverse Functions of BIG-subfamily ARF-GEFs in Plant Growth and Gravitropism.   DOI:  10.3390/ijms20092339 ;  PMID:  31083521
• Non-steroidal Anti-inflammatory Drugs Target TWISTED DWARF1-Regulated Actin Dynamics and Auxin Transport-Mediated Plant Development.   DOI:  10.1016/j.celrep.2020.108463 ;  PMID:  33264621
• AP1G mediates vacuolar acidification during synergid-controlled pollen tube reception.   DOI:  10.1073/pnas.1617967114 ;  PMID:  28559348
• The phosphatidylinositol 3-phosphate effector FYVE3 regulates FYVE2-dependent autophagy in Arabidopsis thaliana.   DOI:  10.3389/fpls.2023.1160162 ;  PMID:  37008475
• Endosidin1 defines a compartment involved in endocytosis of the brassinosteroid receptor BRI1 and the auxin transporters PIN2 and AUX1.   DOI:  10.1073/pnas.0711650105 ;  PMID:  18550817
• Isolation of intact vacuoles and proteomic analysis of tonoplast from suspension-cultured cells of Arabidopsis thaliana.   DOI:  10.1093/pcp/pch099 ;  PMID:  15215502
• An annotation update via cDNA sequence analysis and comprehensive profiling of developmental, hormonal or environmental responsiveness of the Arabidopsis AP2/EREBP transcription factor gene family.   DOI:  10.1007/s11103-005-1511-0 ;  PMID:  16307362
• Function of the anion transporter AtCLC-d in the trans-Golgi network.   DOI:  10.1111/j.1365-313X.2007.03061.x ;  PMID:  17376158
• Rab-A2 and Rab-A3 GTPases define a trans-golgi endosomal membrane domain in Arabidopsis that contributes substantially to the cell plate.   DOI:  10.1105/tpc.107.052001 ;  PMID:  18239134
• Reduced V-ATPase activity in the trans-Golgi network causes oxylipin-dependent hypocotyl growth Inhibition in Arabidopsis.   DOI:  10.1105/tpc.108.058362 ;  PMID:  18441211

Sequences: