Gene Details:
- Gene ID: AT2G28380
- Gene Symbol: AtDRB2, DRB2
- Gene Name: dsRNA-binding protein 2
- Description: dsRNA-binding protein 2;(source:Araport11)
- TAIR Accession: locus:2057491
- Genome: Araport11_genome_release
- Species: Arabidopsis thaliana
Transcripts:
Plant Ontology Annotations:
- PO:0000037 — shoot axis apex — ápice del epiblasto (epiblastema) (Spanish, exact), シュート頂、茎頂 (Japanese, exact)
- PO:0008019 — leaf lamina base — base de la lámina de la hoja (Spanish, exact), 葉身基部 (Japanese, exact)
- PO:0009005 — root — raíz (Spanish, exact), radices (exact, plural), radix (exact), 根 (Japanese, exact), aerial root (narrow), climbing root (narrow)
- PO:0009006 — shoot system — sistema de epiblasto (epiblastema) (Spanish, exact), シュート系、苗条系 (Japanese, exact), Poaceae crown (related), shoot (related), thalli (related), thallus (related), tree crown (narrow)
- PO:0009009 — plant embryo — embrión (Spanish, exact), 植物胚 (Japanese, exact), germ (related), embryo (broad)
- PO:0009025 — vascular leaf — foliage leaf (exact), hoja vascular (Spanish, exact), leaf, vascular (exact), vascular leaves (exact, plural), 維管束のある葉, または維管束植物の葉 (Japanese, exact), crozier (related), macrophyll (related), megaphyll (related), ascidia (narrow), ascidium (narrow), fiddlehead (narrow), frond (narrow), needle-like leaf (narrow), pitcher (narrow), pitcher blade (narrow), pitcher-blade (narrow), scale-like leaf (narrow), sterile frond (narrow), trophophyll (narrow)
- PO:0009029 — stamen — estambre (Spanish, exact), 雄蕊 (Japanese, exact), Poaceae stamen (narrow), Zea stamen (narrow)
- PO:0009031 — sepal — sépalo (Spanish, exact), がく片 (Japanese, exact)
- PO:0009046 — flower — flor (Spanish, exact), 花 (Japanese, exact), floret (related), Asteraceae floret (narrow), basal flower (narrow), double flower (narrow), hermaphrodite flower (narrow), monoclinous flower (narrow), perfect flower (narrow)
- PO:0009052 — inflorescence flower pedicel — 小花柄 (Japanese, related), pedicelo (Spanish, broad)
- PO:0020030 — cotyledon — cotiledón (Spanish, exact), seed leaf (exact), 子葉 (Japanese, exact)
- PO:0020038 — petiole — pecíolo (Spanish, exact), 葉柄 (Japanese, exact)
- PO:0020100 — hypocotyl — hipocótile (Spanish, exact), 胚軸 (Japanese, exact)
- PO:0020137 — leaf apex — ápice de la hoja (Spanish, exact), 葉先 (Japanese, exact), leaf lamina apex (narrow), phyllid apex (narrow)
- PO:0025022 — collective leaf structure — estructura colectiva de hoja (Spanish, exact), leaf series (exact), 葉が集まった構造 (Japanese, exact), leaf whorl (narrow), rosette (narrow), cycle (broad), verticil (broad)
- PO:0025281 — pollen — polen (Spanish, exact), pollen grain (exact), 花粉 (Japanese, exact)
Gene Ontology:
- GO:0005515 — enables — protein binding
- GO:0035196 — acts upstream of or within — miRNA processing
- GO:0003725 — enables — double-stranded RNA binding
- GO:0005737 — located in — cytoplasm
Function-related keywords:
- shoot axis apex , leaf lamina base , root , shoot system , plant embryo , vascular leaf , stamen , sepal , flower , inflorescence flower pedicel , cotyledon , petiole , hypocotyl , leaf apex , collective leaf structure , pollen
Literature:
- Specific interactions between Dicer-like proteins and HYL1/DRB-family dsRNA-binding proteins in Arabidopsis thaliana. DOI: 10.1007/s11103-004-6853-5 ; PMID: 15821876
- Arabidopsis endogenous small RNAs: highways and byways. DOI: 10.1016/j.tplants.2006.07.006 ; PMID: 16893673
- The roles of plant dsRNA-binding proteins in RNAi-like pathways. DOI: 10.1016/j.febslet.2008.07.004 ; PMID: 18625233
- Regulation of imprinted gene expression in Arabidopsis endosperm. DOI: 10.1073/pnas.1019273108 ; PMID: 21257907
- Double-stranded RNA binding proteins DRB2 and DRB4 have an antagonistic impact on polymerase IV-dependent siRNA levels in Arabidopsis. DOI: 10.1261/rna.2680711 ; PMID: 21700726
- DRB2 is required for microRNA biogenesis in Arabidopsis thaliana. DOI: 10.1371/journal.pone.0035933 ; PMID: 22545148
- DRB2, DRB3 and DRB5 function in a non-canonical microRNA pathway in Arabidopsis thaliana. DOI: 10.4161/psb.21518 ; PMID: 22902697
- Parallel action of AtDRB2 and RdDM in the control of transposable element expression. DOI: 10.1186/s12870-015-0455-z ; PMID: 25849103
- MicroRNA Regulatory Mechanisms Play Different Roles in Arabidopsis. DOI: 10.1021/acs.jproteome.5b00616 ; PMID: 26387911
- Chimeric DCL1-Partnering Proteins Provide Insights into the MicroRNA Pathway. DOI: 10.3389/fpls.2015.01201 ; PMID: 26779232
- Double-stranded RNA-binding protein DRB3 negatively regulates anthocyanin biosynthesis by modulating PAP1 expression in Arabidopsis thaliana. DOI: 10.1007/s10265-016-0886-0 ; PMID: 27995376
- Live Cell Imaging Reveals the Relocation of dsRNA Binding Proteins Upon Viral Infection. DOI: 10.1094/MPMI-02-17-0035-R ; PMID: 28296575
- Gene regulation by translational inhibition is determined by Dicer partnering proteins. DOI: 10.1038/nplants.2014.27 ; PMID: 27246880
- The analogous and opposing roles of double-stranded RNA-binding proteins in bacterial resistance. DOI: 10.1093/jxb/erz019 ; PMID: 30843586
- DRB1, DRB2 and DRB4 Are Required for Appropriate Regulation of the microRNA399/PHOSPHATE2 Expression Module in Arabidopsis thaliana. DOI: 10.3390/plants8050124 ; PMID: 31086001
- Characterization of a DCL2-Insensitive Tomato Bushy Stunt Virus Isolate Infecting Arabidopsis thaliana. DOI: 10.3390/v12101121 ; PMID: 33023227
- MicroRNA-Mediated Responses to Cadmium Stress in Arabidopsis thaliana. DOI: 10.3390/plants10010130 ; PMID: 33435199
- Immunocapture of dsRNA-bound proteins provides insight into Tobacco rattle virus replication complexes and reveals Arabidopsis DRB2 to be a wide-spectrum antiviral effector. DOI: 10.1093/plcell/koab214 ; PMID: 34436604
- The roles of plant dsRNA-binding proteins in RNAi-like pathways. DOI: 10.1016/j.febslet.2008.07.004 ; PMID: 18625233
Sequences:
cDNA Sequence
- >AT2G28380.1
GCAGATAATTAATTCTCACATTTAATTTTATTTTATTTTTTCCATTAAAGCAAAAACCCCACACTCTCTCTCTCTCTTGCTCCTCCCTCTCTTCCTCTCTCTATCTCTCTCTGCAAAAACCCTAAATTTCCTCCGATTTCACCATCTTCAATCTCCTTCACACCCCAACTTAGCCTCTTAATCACTCCCCAAGCTAAACCCTCCAACGATTTTCCATGATTCGAAGATACAGAGCCTTAGCGATGAAGAAAAAGCCCTAAAAACCAAAGCTTTGATCTCTCCGAAATCGGAGTTTCTTTCTTTGTTTGGTAAATTTGGTTTTCGAAATGTATAAGAACCAGCTACAAGAGTTGGCTCAGAGGAGCTGCTTTAATCTTCCTTCGTATACTTGTATTAGGGAAGGTCCTGACCACGCGCCGCGATTCAAGGCTACTGTTAACTTTAACGGCGAGATCTTTGAGAGTCCTCAGTATTGTTCTACTCTTCGTCAAGCTGAACACTCTGCTGCTGAAGTTGCTCTCAATGCTCTCTCTAATCGTGGTCCTTCTCACTCTCTTGCCGCCAGGATCTTGGATGAGACGGGTGTGTATAAGAATCTTTTGCAAGAGATAGCTCAAAGAGTGGGAGCTCCTTTACCGCGATATACTACTTTCAGGTCAGGTCTTGGTCACCAACCTGTGTTTACTGGTACTGTAGAATTGGCTGGAATTACGTTCACTGGAGATCCAGCTAAGAACAAGAAGCAAGCAGAGAAGAATGCTGCAATGGCTGCTTGGTCTTCCCTAAAACAATTGGCAAAAGAAACATCAAGTTCAATGCCTGAGCCTGAGAACATTGACGAACTAGAACAGGTGATTATAGCAAGAGCTTTGATAAACTATCGTATCAAGGAAAACATTGGCACAGGAAGCTCCTCGAGTGCCCCAGTTCCATTTGCAAAGAAGTTCTTTATGCAGAACCTTAGACCAACAAGTCCACAGCCTTCTCCTGCAACCACATCGAGAATCTTACCCTTTATTTGCCCAAAACAACCTTCCAGAAGCAGCAGATCATCCTTAGCAGCAACTTCCGGTATTGACAGAATTATGGCAGCAGCCTTGGAAAGCCGCAGCTACCAGCGGCCTCAGCAGAGATTTGCAAATCCGCCTTATGTTCCTATGAGGCAATTTAGATCGCAATGCCATGGGATGGCTCCACCTGTCACAATCAGAACCGCTGTACCGGTCTTCTCTGCACCTCCAATGCCTCCTCCACCATGTACAAACAACACTCAGCTACCTTCTTCTGTGTATGTCCCATCGCTGATGCGAACTGCACCACCTGTGAGGATCGCGCCGCCTGTCACAATCAGAACCGCGGTGCCCGTATTTGCTTCTGCGCCACCGGTTAGAATTAGAACCGCTGTGAAGCCCACAGTTGAGGCAGGAGAAACCCGCATATCATCAGTCCAAGAAAAGGAGAGTATACCAGTCTTGCCTGATAGTCTTGAAATTGGAGTAGAAGGAAGTACTATAACAATTACAGATTGTGAGAAAACAGCGTCAAAGGAAACCGAGAGAGCAGAGTTTAAGGATTCATCGAAAGGAGAACCGGAGACAGCAAGAGAGCGACTGGAGAACCTAAAGATCTGATGCCTTGAAGACTGTCTCTGGGTTTAGTTTTTTTTGAGGTTGGTTTCTGAAAATTGTTACATTAGTAATCTCGTTCGTTATTATACTCGGTGGATCGAGTAGTTTGATAATCCGAAAGATTTGTATTATATTGGGGAGTTTTGGGAAGAACCTGGCCATCTCTGGATTGTAGAATTGTATCAGTTTCGCTTCCTATTCAGTTTGTTTGTGTCCTTTTTCTCATCTTTTATAAATCTGTTACCTATCGTTGTTCCAGCAGAATCAAGCTCTTTGTCTTACACGACAGCTATGACACATATCTCAATGAGTCTTTGGAACTTCGAATTTCTCCTTTAGCTAACAAATTCAGTCAAAATATTTCAGCAC
CDS Sequence
- >AT2G28380.1
ATGTATAAGAACCAGCTACAAGAGTTGGCTCAGAGGAGCTGCTTTAATCTTCCTTCGTATACTTGTATTAGGGAAGGTCCTGACCACGCGCCGCGATTCAAGGCTACTGTTAACTTTAACGGCGAGATCTTTGAGAGTCCTCAGTATTGTTCTACTCTTCGTCAAGCTGAACACTCTGCTGCTGAAGTTGCTCTCAATGCTCTCTCTAATCGTGGTCCTTCTCACTCTCTTGCCGCCAGGATCTTGGATGAGACGGGTGTGTATAAGAATCTTTTGCAAGAGATAGCTCAAAGAGTGGGAGCTCCTTTACCGCGATATACTACTTTCAGGTCAGGTCTTGGTCACCAACCTGTGTTTACTGGTACTGTAGAATTGGCTGGAATTACGTTCACTGGAGATCCAGCTAAGAACAAGAAGCAAGCAGAGAAGAATGCTGCAATGGCTGCTTGGTCTTCCCTAAAACAATTGGCAAAAGAAACATCAAGTTCAATGCCTGAGCCTGAGAACATTGACGAACTAGAACAGGTGATTATAGCAAGAGCTTTGATAAACTATCGTATCAAGGAAAACATTGGCACAGGAAGCTCCTCGAGTGCCCCAGTTCCATTTGCAAAGAAGTTCTTTATGCAGAACCTTAGACCAACAAGTCCACAGCCTTCTCCTGCAACCACATCGAGAATCTTACCCTTTATTTGCCCAAAACAACCTTCCAGAAGCAGCAGATCATCCTTAGCAGCAACTTCCGGTATTGACAGAATTATGGCAGCAGCCTTGGAAAGCCGCAGCTACCAGCGGCCTCAGCAGAGATTTGCAAATCCGCCTTATGTTCCTATGAGGCAATTTAGATCGCAATGCCATGGGATGGCTCCACCTGTCACAATCAGAACCGCTGTACCGGTCTTCTCTGCACCTCCAATGCCTCCTCCACCATGTACAAACAACACTCAGCTACCTTCTTCTGTGTATGTCCCATCGCTGATGCGAACTGCACCACCTGTGAGGATCGCGCCGCCTGTCACAATCAGAACCGCGGTGCCCGTATTTGCTTCTGCGCCACCGGTTAGAATTAGAACCGCTGTGAAGCCCACAGTTGAGGCAGGAGAAACCCGCATATCATCAGTCCAAGAAAAGGAGAGTATACCAGTCTTGCCTGATAGTCTTGAAATTGGAGTAGAAGGAAGTACTATAACAATTACAGATTGTGAGAAAACAGCGTCAAAGGAAACCGAGAGAGCAGAGTTTAAGGATTCATCGAAAGGAGAACCGGAGACAGCAAGAGAGCGACTGGAGAACCTAAAGATCTGA
Protein Sequence
- >AT2G28380.1
MYKNQLQELAQRSCFNLPSYTCIREGPDHAPRFKATVNFNGEIFESPQYCSTLRQAEHSAAEVALNALSNRGPSHSLAARILDETGVYKNLLQEIAQRVGAPLPRYTTFRSGLGHQPVFTGTVELAGITFTGDPAKNKKQAEKNAAMAAWSSLKQLAKETSSSMPEPENIDELEQVIIARALINYRIKENIGTGSSSSAPVPFAKKFFMQNLRPTSPQPSPATTSRILPFICPKQPSRSSRSSLAATSGIDRIMAAALESRSYQRPQQRFANPPYVPMRQFRSQCHGMAPPVTIRTAVPVFSAPPMPPPPCTNNTQLPSSVYVPSLMRTAPPVRIAPPVTIRTAVPVFASAPPVRIRTAVKPTVEAGETRISSVQEKESIPVLPDSLEIGVEGSTITITDCEKTASKETERAEFKDSSKGEPETARERLENLKI