Information report for AT2G28160
Gene Details
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Functional Descriptions
- PO:0009005 — root — raíz (Spanish, exact), radices (exact, plural), radix (exact), 根 (Japanese, exact), aerial root (narrow), climbing root (narrow)
Functional Keywords
Literature and News
- Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes. DOI: 10.1126/science.290.5499.2105 ; PMID: 11118137
- The basic helix-loop-helix transcription factor family in plants: a genome-wide study of protein structure and functional diversity. DOI: 10.1093/molbev/msg088 ; PMID: 12679534
- Expression profiling of cytokinin action in Arabidopsis. DOI: 10.1104/pp.103.021436 ; PMID: 12913156
- The Arabidopsis basic/helix-loop-helix transcription factor family. DOI: 10.1105/tpc.013839 ; PMID: 12897250
- Update on the basic helix-loop-helix transcription factor gene family in Arabidopsis thaliana. DOI: 10.1105/tpc.151140 ; PMID: 14600211
- The essential basic helix-loop-helix protein FIT1 is required for the iron deficiency response. DOI: 10.1105/tpc.104.024315 ; PMID: 15539473
- Analysis of sequence, map position, and gene expression reveals conserved essential genes for iron uptake in Arabidopsis and tomato. DOI: 10.1104/pp.104.047233 ; PMID: 15531708
- AtbHLH29 of Arabidopsis thaliana is a functional ortholog of tomato FER involved in controlling iron acquisition in strategy I plants. DOI: 10.1038/sj.cr.7290331 ; PMID: 16117851
- 12-oxo-phytodienoic acid triggers expression of a distinct set of genes and plays a role in wound-induced gene expression in Arabidopsis. DOI: 10.1104/pp.105.067058 ; PMID: 16258017
- FRU (BHLH029) is required for induction of iron mobilization genes in Arabidopsis thaliana. DOI: 10.1016/j.febslet.2004.10.062 ; PMID: 15556641
- Genome-wide expression profiling of ARABIDOPSIS RESPONSE REGULATOR 7(ARR7) overexpression in cytokinin response. DOI: 10.1007/s00438-006-0177-x ; PMID: 17061125
- FIT, the FER-LIKE IRON DEFICIENCY INDUCED TRANSCRIPTION FACTOR in Arabidopsis. DOI: 10.1016/j.plaphy.2007.03.006 ; PMID: 17466530
- Iron deficiency-mediated stress regulation of four subgroup Ib BHLH genes in Arabidopsis thaliana. DOI: 10.1007/s00425-007-0535-x ; PMID: 17516080
- Cytokinins negatively regulate the root iron uptake machinery in Arabidopsis through a growth-dependent pathway. DOI: 10.1111/j.1365-313X.2008.03502.x ; PMID: 18397377
- A soil bacterium regulates plant acquisition of iron via deficiency-inducible mechanisms. DOI: 10.1111/j.1365-313X.2009.03803.x ; PMID: 19154225
- FIT interacts with AtbHLH38 and AtbHLH39 in regulating iron uptake gene expression for iron homeostasis in Arabidopsis. DOI: 10.1038/cr.2008.26 ; PMID: 18268542
- Carbon monoxide improves adaptation of Arabidopsis to iron deficiency. DOI: 10.1111/j.1467-7652.2009.00469.x ; PMID: 20055961
- Ethylene and nitric oxide involvement in the up-regulation of key genes related to iron acquisition and homeostasis in Arabidopsis. DOI: 10.1093/jxb/erq203 ; PMID: 20627899
- Interaction between the bHLH transcription factor FIT and ETHYLENE INSENSITIVE3/ETHYLENE INSENSITIVE3-LIKE1 reveals molecular linkage between the regulation of iron acquisition and ethylene signaling in Arabidopsis. DOI: 10.1105/tpc.111.084715 ; PMID: 21586684
- Fitting into the harsh reality: regulation of iron-deficiency responses in dicotyledonous plants. DOI: 10.1093/mp/ssr065 ; PMID: 21873619
- Suppression of Fe deficiency gene expression by jasmonate. DOI: 10.1016/j.plaphy.2011.01.025 ; PMID: 21334215
- Posttranslational regulation of the iron deficiency basic helix-loop-helix transcription factor FIT is affected by iron and nitric oxide. DOI: 10.1104/pp.111.183285 ; PMID: 21972265
- Reciprocal interaction of the circadian clock with the iron homeostasis network in Arabidopsis. DOI: 10.1104/pp.112.208603 ; PMID: 23250624
- Looking for the hub in Fe signaling. DOI: 10.4161/psb.20150 ; PMID: 22580691
- Feruloyl-CoA 6'-Hydroxylase1-dependent coumarins mediate iron acquisition from alkaline substrates in Arabidopsis. DOI: 10.1104/pp.113.228544 ; PMID: 24246380
- Uranium perturbs signaling and iron uptake response in Arabidopsis thaliana roots. DOI: 10.1039/c4mt00005f ; PMID: 24549117
- Iron and FER-LIKE IRON DEFICIENCY-INDUCED TRANSCRIPTION FACTOR-dependent regulation of proteins and genes in Arabidopsis thaliana roots. DOI: 10.1002/pmic.201400351 ; PMID: 25951126
- Carbon Monoxide Interacts with Auxin and Nitric Oxide to Cope with Iron Deficiency in Arabidopsis. DOI: 10.3389/fpls.2016.00112 ; PMID: 27014280
- Paenibacillus polymyxa BFKC01 enhances plant iron absorption via improved root systems and activated iron acquisition mechanisms. DOI: 10.1016/j.plaphy.2016.04.025 ; PMID: 27105423
- Exogenous Melatonin Improves Plant Iron Deficiency Tolerance via Increased Accumulation of Polyamine-Mediated Nitric Oxide. DOI: 10.3390/ijms17111777 ; PMID: 27792144
- The G-Box Transcriptional Regulatory Code in Arabidopsis. DOI: 10.1104/pp.17.01086 ; PMID: 28864470
- S-Nitrosoglutathione works downstream of nitric oxide to mediate iron-deficiency signaling in Arabidopsis. DOI: 10.1111/tpj.13850 ; PMID: 29396986
- Four IVa bHLH Transcription Factors Are Novel Interactors of FIT and Mediate JA Inhibition of Iron Uptake in Arabidopsis. DOI: 10.1016/j.molp.2018.06.005 ; PMID: 29960107
- The Putative Peptide Gene FEP1 Regulates Iron Deficiency Response in Arabidopsis. DOI: 10.1093/pcp/pcy145 ; PMID: 30032190
- The basic helix-loop-helix transcription factor, bHLH11 functions in the iron-uptake system in Arabidopsis thaliana. DOI: 10.1007/s10265-018-1068-z ; PMID: 30417276
- New aspects of iron-copper crosstalk uncovered by transcriptomic characterization of Col-0 and the copper uptake mutant spl7 in Arabidopsis thaliana. DOI: 10.1039/c8mt00287h ; PMID: 30460953
- CIPK11-Dependent Phosphorylation Modulates FIT Activity to Promote Arabidopsis Iron Acquisition in Response to Calcium Signaling. DOI: 10.1016/j.devcel.2019.01.006 ; PMID: 30713077
- Small-Molecules Selectively Modulate Iron-Deficiency Signaling Networks in Arabidopsis. DOI: 10.3389/fpls.2019.00008 ; PMID: 30766541
- Iron and Phosphate Deficiency Regulators Concertedly Control Coumarin Profiles in Arabidopsis thaliana Roots During Iron, Phosphate, and Combined Deficiencies. DOI: 10.3389/fpls.2019.00113 ; PMID: 30804973
- PRC2-Mediated H3K27me3 Contributes to Transcriptional Regulation of FIT-Dependent Iron Deficiency Response. DOI: 10.3389/fpls.2019.00627 ; PMID: 31156682
- FIT-Binding Proteins and Their Functions in the Regulation of Fe Homeostasis. DOI: 10.3389/fpls.2019.00844 ; PMID: 31297128
- Arabidopsis BRUTUS-LIKE E3 ligases negatively regulate iron uptake by targeting transcription factor FIT for recycling. DOI: 10.1073/pnas.1907971116 ; PMID: 31413196
- Phospho-mutant activity assays provide evidence for alternative phospho-regulation pathways of the transcription factor FER-LIKE IRON DEFICIENCY-INDUCED TRANSCRIPTION FACTOR. DOI: 10.1111/nph.16168 ; PMID: 31487399
- The iron deficiency response in Arabidopsis thaliana requires the phosphorylated transcription factor URI. DOI: 10.1073/pnas.1916892116 ; PMID: 31776249
- The Transcription Factor bHLH121 Interacts with bHLH105 (ILR3) and Its Closest Homologs to Regulate Iron Homeostasis in Arabidopsis. DOI: 10.1105/tpc.19.00541 ; PMID: 31776233
- Mobility and localization of the iron deficiency-induced transcription factor bHLH039 change in the presence of FIT. DOI: 10.1002/pld3.190 ; PMID: 31879716
- Putative cis-Regulatory Elements Predict Iron Deficiency Responses in Arabidopsis Roots. DOI: 10.1104/pp.19.00760 ; PMID: 31937681
- bHLH121 Functions as a Direct Link that Facilitates the Activation of FIT by bHLH IVc Transcription Factors for Maintaining Fe Homeostasis in Arabidopsis. DOI: 10.1016/j.molp.2020.01.006 ; PMID: 31962167
- Alteration of iron responsive gene expression in Arabidopsis glutaredoxin S17 loss of function plants with or without iron stress. DOI: 10.1080/15592324.2020.1758455 ; PMID: 32351167
- Deregulated High Affinity Copper Transport Alters Iron Homeostasis in Arabidopsis. DOI: 10.3389/fpls.2020.01106 ; PMID: 32793263
- The kinase CIPK11 functions as a positive regulator in cadmium stress response in Arabidopsis. DOI: 10.1016/j.gene.2020.145372 ; PMID: 33346096
- All together now: regulation of the iron deficiency response. DOI: 10.1093/jxb/erab003 ; PMID: 33449088
- FIT and bHLH Ib transcription factors modulate iron and copper crosstalk in Arabidopsis. DOI: 10.1111/pce.14000 ; PMID: 33464620
- Comparative Study of Several Fe Deficiency Responses in the Arabidopsis thaliana Ethylene Insensitive Mutants ein2-1 and ein2-5. DOI: 10.3390/plants10020262 ; PMID: 33573082
- PAP/SAL1 retrograde signaling pathway modulates iron deficiency response in alkaline soils. DOI: 10.1016/j.plantsci.2020.110808 ; PMID: 33568304
- Interconnection of iron and osmotic stress signalling in plants: is FIT a regulatory hub to cross-connect abscisic acid responses? DOI: 10.1111/plb.13261 ; PMID: 33772999
- Physiological and interactomic analysis reveals versatile functions of Arabidopsis 14-3-3 quadruple mutants in response to Fe deficiency. DOI: 10.1038/s41598-021-94908-9 ; PMID: 34330973
- bHLH11 inhibits bHLH IVc proteins by recruiting the TOPLESS/TOPLESS-RELATED corepressors. DOI: 10.1093/plphys/kiab540 ; PMID: 34894263
- Loss-of-function mutations in the ERF96 gene enhance iron-deficient tolerance in Arabidopsis. DOI: 10.1016/j.plaphy.2022.02.002 ; PMID: 35158317
- MNB1 gene is involved in regulating the iron-deficiency stress response in Arabidopsis thaliana. DOI: 10.1186/s12870-022-03553-5 ; PMID: 35346040
- Crosstalk Between Iron and Sulfur Homeostasis Networks in Arabidopsis. DOI: 10.3389/fpls.2022.878418 ; PMID: 35755678
- ZAT10 plays dual roles in cadmium uptake and detoxification in Arabidopsis. DOI: 10.3389/fpls.2022.994100 ; PMID: 36110357
- Fe deficiency-induced ethylene synthesis confers resistance to Botrytis cinerea. DOI: 10.1111/nph.18638 ; PMID: 36440498
- The transcription factor MYC1 interacts with FIT to negatively regulate iron homeostasis in Arabidopsis thaliana. DOI: 10.1111/tpj.16130 ; PMID: 36721966
- Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes. DOI: 10.1126/science.290.5499.2105 ; PMID: 11118137
- The basic helix-loop-helix transcription factor family in plants: a genome-wide study of protein structure and functional diversity. DOI: 10.1093/molbev/msg088 ; PMID: 12679534
- Analysis of sequence, map position, and gene expression reveals conserved essential genes for iron uptake in Arabidopsis and tomato. DOI: 10.1104/pp.104.047233 ; PMID: 15531708
- The tomato fer gene encoding a bHLH protein controls iron-uptake responses in roots. DOI: 10.1073/pnas.212448699 ; PMID: 12370409
- AtIREG2 encodes a tonoplast transport protein involved in iron-dependent nickel detoxification in Arabidopsis thaliana roots. DOI: 10.1074/jbc.M601062200 ; PMID: 16790430
- FIT, the FER-LIKE IRON DEFICIENCY INDUCED TRANSCRIPTION FACTOR in Arabidopsis. DOI: 10.1016/j.plaphy.2007.03.006 ; PMID: 17466530
- Cytokinins negatively regulate the root iron uptake machinery in Arabidopsis through a growth-dependent pathway. DOI: 10.1111/j.1365-313X.2008.03502.x ; PMID: 18397377
Gene Resources
- UniProt: A0A1P8AYH9
- EMBL: CP002685
- AlphaFoldDB: A0A1P8AYH9
- EnsemblPlants: AT2G28160.2
- Gramene: AT2G28160.2
- ExpressionAtlas: AT2G28160
- InterPro: IPR011598, IPR036638, IPR051358
- PANTHER: PTHR31945, PTHR31945:SF17
- SUPFAM: SSF47459
- PROSITE: PS50888
- Gene3D: 4.10.280.10
- OrthoDB: A0A1P8AYH9
- SWISS-MODEL: A0A1P8AYH9
- Conserved Domain Database: cd11450
Homologs
- Brassica napus GSBRNA2T00148180001, GSBRNA2T00118718001, GSBRNA2T00047327001, GSBRNA2T00138840001, GSBRNA2T00127778001
- Brassica oleracea XP_013634471.1, XP_013634470.1, XP_013622671.1, XP_013634885.1
- Brassica rapa XP_009103653.1, XP_009133880.1, XP_009140847.1
- Raphanus raphanistrum RrC10775_p1
Sequences
cDNA Sequence
- >AT2G28160.2
CAAAAACACACAAATGGAAGGAAGAGTCAACGCTCTGTCAAACATAAACGATCTCGAACTTCACAATTTCTTGGTCGATCCAAACTTCGATCAGTTCATAAACCTCATAAGAGGAGATCATCAAACCATTGACGAAAACCCAGTTCTTGATTTCGATCTTGGTCCATTACAAAACAGCCCCTGTTTCATAGACGAGAACCAGTTCATCCCAACACCTGTCGATGACCTCTTCGACGAATTGCCTGACTTAGACTCCAACGTTGCTGAATCATTCCGTAGCTTCGACGGTGATAGTGTTAGAGCCGGTGGTGAAGAAGATGAAGAAGATTACAACGACGGTGATGATTCTTCAGCCACTACTACGAATAATGATGGGACCCGTAAGACGAAGACTGATCGGTCTAGGACTTTGATCTCTGAGAGAAGAAGGAGAGGGCGTATGAAGGATAAGCTTTATGCATTGAGATCTCTTGTTCCCAATATTACTAAGATGGATAAAGCATCCATTGTTGGAGATGCAGTGTTGTATGTTCAAGAACTTCAGTCACAAGCGAAGAAACTCAAATCCGATATCGCGGGTCTTGAAGCTTCTTTAAACTCTACTGGAGGGTACCAAGAACATGCTCCTGATGCTCAAAAGACTCAACCTTTTCGCGGTATCAATCCTCCTGCTTCCAAAAAAATCATTCAGATGGATGTTATACAAGTGGAGGAGAAAGGGTTTTATGTGAGATTGGTGTGTAACAAAGGAGAAGGTGTTGCTCCATCTCTTTACAAGTCTTTGGAGTCTCTTACAAGTTTCCAAGTGCAGAACTCTAACCTAAGCTCTCCTTCTCCGGACACATACCTCTTAACATATACCTTAGATGGGACATGCTTCGAACAGAGCTTAAACTTGCCTAACCTGAAGCTGTGGATCACTGGATCACTTTTAAATCAAGGGCTCTAATTTCTATTCTAGTGATGATGTAACCGAGATTGTTGATTCTCTATTGAATAAACACCATGTTATATAGTAATTTAGCGACAAATTGTATGGTTAAATGAAGTAATATTTATGTTTTGTTT - >AT2G28160.1
CAAAAACACACAAATGGAAGGAAGAGTCAACGCTCTGTCAAACATAAACGATCTCGAACTTCACAATTTCTTGGTCGATCCAAACTTCGATCAGTTCATAAACCTCATAAGAGGAGATCATCAAACCATTGACGAAAACCCAGTTCTTGATTTCGATCTTGGTCCATTACAAAACAGCCCCTGTTTCATAGACGAGAACCAGTTCATCCCAACACCTGTCGATGACCTCTTCGACGAATTGCCTGACTTAGACTCCAACGTTGCTGAATCATTCCGTAGCTTCGACGGTGATAGTGTTAGAGCCGGTGGTGAAGAAGATGAAGAAGATTACAACGACGGTGATGATTCTTCAGCCACTACTACGAATAATGATGGGACCCGTAAGACGAAGACTGATCGGTCTAGGACTTTGATCTCTGAGAGAAGAAGGAGAGGGCGTATGAAGGATAAGCTTTATGCATTGAGATCTCTTGTTCCCAATATTACTAAGATGGATAAAGCATCCATTGTTGGAGATGCAGTGTTGTATGTTCAAGAACTTCAGTCACAAGCGAAGAAACTCAAATCCGATATCGCGGGTCTTGAAGCTTCTTTAAACTCTACTGGAGGGTACCAAGAACATGCTCCTGATGCTCAAAAGACTCAACCTTTTCGCGGTATCAATCCTCCTGCTTCCAAAAAAATCATTCAGATGGATGTTATACAAGTGGAGGAGAAAGGGTTTTATGTGAGATTGGTGTGTAACAAAGGAGAAGGTGTTGCTCCATCTCTTTACAAGTCTTTGGAGTCTCTTACAAGTTTCCAAGTGCAGAACTCTAACCTAAGCTCTCCTTCTCCGGACACATACCTCTTAACATATACCTTAGATGGGACATGCTTCGAACAGAGCTTAAACTTGCCTAACCTGAAGCTGTGGATCACTGGATCACTTTTAAATCAAGGGCTCTAATTTCTATTCTAGTGATGATGTAACCGAGATTGTTGATTCTCTATTGAATAAACACCATGTTATATAGTAATTTAGCGACAAATTGTATGGTTAAATGAAGTAATATTTATGTTTTGTTT
CDS Sequence
- >AT2G28160.2
ATGGAAGGAAGAGTCAACGCTCTGTCAAACATAAACGATCTCGAACTTCACAATTTCTTGGTCGATCCAAACTTCGATCAGTTCATAAACCTCATAAGAGGAGATCATCAAACCATTGACGAAAACCCAGTTCTTGATTTCGATCTTGGTCCATTACAAAACAGCCCCTGTTTCATAGACGAGAACCAGTTCATCCCAACACCTGTCGATGACCTCTTCGACGAATTGCCTGACTTAGACTCCAACGTTGCTGAATCATTCCGTAGCTTCGACGGTGATAGTGTTAGAGCCGGTGGTGAAGAAGATGAAGAAGATTACAACGACGGTGATGATTCTTCAGCCACTACTACGAATAATGATGGGACCCGTAAGACGAAGACTGATCGGTCTAGGACTTTGATCTCTGAGAGAAGAAGGAGAGGGCGTATGAAGGATAAGCTTTATGCATTGAGATCTCTTGTTCCCAATATTACTAAGATGGATAAAGCATCCATTGTTGGAGATGCAGTGTTGTATGTTCAAGAACTTCAGTCACAAGCGAAGAAACTCAAATCCGATATCGCGGGTCTTGAAGCTTCTTTAAACTCTACTGGAGGGTACCAAGAACATGCTCCTGATGCTCAAAAGACTCAACCTTTTCGCGGTATCAATCCTCCTGCTTCCAAAAAAATCATTCAGATGGATGTTATACAAGTGGAGGAGAAAGGGTTTTATGTGAGATTGGTGTGTAACAAAGGAGAAGGTGTTGCTCCATCTCTTTACAAGTCTTTGGAGTCTCTTACAAGTTTCCAAGTGCAGAACTCTAACCTAAGCTCTCCTTCTCCGGACACATACCTCTTAACATATACCTTAGATGGGACATGCTTCGAACAGAGCTTAAACTTGCCTAACCTGAAGCTGTGGATCACTGGATCACTTTTAAATCAAGGGCTCTAA - >AT2G28160.1
ATGGAAGGAAGAGTCAACGCTCTGTCAAACATAAACGATCTCGAACTTCACAATTTCTTGGTCGATCCAAACTTCGATCAGTTCATAAACCTCATAAGAGGAGATCATCAAACCATTGACGAAAACCCAGTTCTTGATTTCGATCTTGGTCCATTACAAAACAGCCCCTGTTTCATAGACGAGAACCAGTTCATCCCAACACCTGTCGATGACCTCTTCGACGAATTGCCTGACTTAGACTCCAACGTTGCTGAATCATTCCGTAGCTTCGACGGTGATAGTGTTAGAGCCGGTGGTGAAGAAGATGAAGAAGATTACAACGACGGTGATGATTCTTCAGCCACTACTACGAATAATGATGGGACCCGTAAGACGAAGACTGATCGGTCTAGGACTTTGATCTCTGAGAGAAGAAGGAGAGGGCGTATGAAGGATAAGCTTTATGCATTGAGATCTCTTGTTCCCAATATTACTAAGATGGATAAAGCATCCATTGTTGGAGATGCAGTGTTGTATGTTCAAGAACTTCAGTCACAAGCGAAGAAACTCAAATCCGATATCGCGGGTCTTGAAGCTTCTTTAAACTCTACTGGAGGGTACCAAGAACATGCTCCTGATGCTCAAAAGACTCAACCTTTTCGCGGTATCAATCCTCCTGCTTCCAAAAAAATCATTCAGATGGATGTTATACAAGTGGAGGAGAAAGGGTTTTATGTGAGATTGGTGTGTAACAAAGGAGAAGGTGTTGCTCCATCTCTTTACAAGTCTTTGGAGTCTCTTACAAGTTTCCAAGTGCAGAACTCTAACCTAAGCTCTCCTTCTCCGGACACATACCTCTTAACATATACCTTAGATGGGACATGCTTCGAACAGAGCTTAAACTTGCCTAACCTGAAGCTGTGGATCACTGGATCACTTTTAAATCAAGGGCTCTAA
Protein Sequence
- >AT2G28160.2
MEGRVNALSNINDLELHNFLVDPNFDQFINLIRGDHQTIDENPVLDFDLGPLQNSPCFIDENQFIPTPVDDLFDELPDLDSNVAESFRSFDGDSVRAGGEEDEEDYNDGDDSSATTTNNDGTRKTKTDRSRTLISERRRRGRMKDKLYALRSLVPNITKMDKASIVGDAVLYVQELQSQAKKLKSDIAGLEASLNSTGGYQEHAPDAQKTQPFRGINPPASKKIIQMDVIQVEEKGFYVRLVCNKGEGVAPSLYKSLESLTSFQVQNSNLSSPSPDTYLLTYTLDGTCFEQSLNLPNLKLWITGSLLNQGL - >AT2G28160.1
MEGRVNALSNINDLELHNFLVDPNFDQFINLIRGDHQTIDENPVLDFDLGPLQNSPCFIDENQFIPTPVDDLFDELPDLDSNVAESFRSFDGDSVRAGGEEDEEDYNDGDDSSATTTNNDGTRKTKTDRSRTLISERRRRGRMKDKLYALRSLVPNITKMDKASIVGDAVLYVQELQSQAKKLKSDIAGLEASLNSTGGYQEHAPDAQKTQPFRGINPPASKKIIQMDVIQVEEKGFYVRLVCNKGEGVAPSLYKSLESLTSFQVQNSNLSSPSPDTYLLTYTLDGTCFEQSLNLPNLKLWITGSLLNQGL