Gene Details:
- Gene ID: AT2G27960
- Gene Symbol: CKS1, CKS1AT
- Gene Name: cyclin-dependent kinase-subunit 1
- Description: cyclin-dependent kinase-subunit 1;(source:Araport11)
- TAIR Accession: locus:2057836
- Genome: Araport11_genome_release
- Species: Arabidopsis thaliana
Transcripts:
Plant Ontology Annotations:
- PO:0000017 — vascular leaf primordium — leaf primordium (exact), portion of vascular leaf primordium tissue (exact), primordio de hoja (Spanish, exact), vascular leaf primordia (exact, plural), 葉原基 (Japanese, exact)
- PO:0020144 — apical meristem — AM (exact), meristema apical (Spanish, exact), 頂端分裂組織 (Japanese, exact), primary meristem (related), promeristem (broad)
- PO:0025275 — procambium — procambio (Spanish, exact), 前形成層 (Japanese, exact)
- PO:0000037 — shoot axis apex — ápice del epiblasto (epiblastema) (Spanish, exact), シュート頂、茎頂 (Japanese, exact)
- PO:0008019 — leaf lamina base — base de la lámina de la hoja (Spanish, exact), 葉身基部 (Japanese, exact)
- PO:0009005 — root — raíz (Spanish, exact), radices (exact, plural), radix (exact), 根 (Japanese, exact), aerial root (narrow), climbing root (narrow)
- PO:0009006 — shoot system — sistema de epiblasto (epiblastema) (Spanish, exact), シュート系、苗条系 (Japanese, exact), Poaceae crown (related), shoot (related), thalli (related), thallus (related), tree crown (narrow)
- PO:0009009 — plant embryo — embrión (Spanish, exact), 植物胚 (Japanese, exact), germ (related), embryo (broad)
- PO:0009025 — vascular leaf — foliage leaf (exact), hoja vascular (Spanish, exact), leaf, vascular (exact), vascular leaves (exact, plural), 維管束のある葉, または維管束植物の葉 (Japanese, exact), crozier (related), macrophyll (related), megaphyll (related), ascidia (narrow), ascidium (narrow), fiddlehead (narrow), frond (narrow), needle-like leaf (narrow), pitcher (narrow), pitcher blade (narrow), pitcher-blade (narrow), scale-like leaf (narrow), sterile frond (narrow), trophophyll (narrow)
- PO:0009029 — stamen — estambre (Spanish, exact), 雄蕊 (Japanese, exact), Poaceae stamen (narrow), Zea stamen (narrow)
- PO:0009031 — sepal — sépalo (Spanish, exact), がく片 (Japanese, exact)
- PO:0009046 — flower — flor (Spanish, exact), 花 (Japanese, exact), floret (related), Asteraceae floret (narrow), basal flower (narrow), double flower (narrow), hermaphrodite flower (narrow), monoclinous flower (narrow), perfect flower (narrow)
- PO:0009052 — inflorescence flower pedicel — 小花柄 (Japanese, related), pedicelo (Spanish, broad)
- PO:0020030 — cotyledon — cotiledón (Spanish, exact), seed leaf (exact), 子葉 (Japanese, exact)
- PO:0020038 — petiole — pecíolo (Spanish, exact), 葉柄 (Japanese, exact)
- PO:0020100 — hypocotyl — hipocótile (Spanish, exact), 胚軸 (Japanese, exact)
- PO:0020137 — leaf apex — ápice de la hoja (Spanish, exact), 葉先 (Japanese, exact), leaf lamina apex (narrow), phyllid apex (narrow)
- PO:0025022 — collective leaf structure — estructura colectiva de hoja (Spanish, exact), leaf series (exact), 葉が集まった構造 (Japanese, exact), leaf whorl (narrow), rosette (narrow), cycle (broad), verticil (broad)
- PO:0025281 — pollen — polen (Spanish, exact), pollen grain (exact), 花粉 (Japanese, exact)
- PO:0000084 — plant sperm cell — célula espermática o esperma (Spanish, exact), male gamete (exact), microgamete (exact), 植物精子細胞 (Japanese, exact), sperm nucleus (related), sperm cell (broad)
Gene Ontology:
- GO:0005515 — enables — protein binding
- GO:0042023 — acts upstream of or within — DNA endoreduplication
- GO:0043130 — enables — ubiquitin binding
- GO:0007346 — involved in — regulation of mitotic cell cycle
- GO:0051726 — acts upstream of or within — regulation of cell cycle
- GO:0005777 — located in — peroxisome
- GO:0019005 — part of — SCF ubiquitin ligase complex
- GO:0005634 — located in — nucleus
- GO:0042393 — enables — histone binding
- GO:0019901 — enables — protein kinase binding
- GO:0061575 — enables — cyclin-dependent protein serine/threonine kinase activator activity
- GO:0000307 — part of — cyclin-dependent protein kinase holoenzyme complex
- GO:0000278 — acts upstream of or within — mitotic cell cycle
- GO:0005737 — located in — cytoplasm
Function-related keywords:
- vascular leaf primordium , apical meristem , procambium , shoot axis apex , leaf lamina base , root , shoot system , plant embryo , vascular leaf , stamen , sepal , flower , inflorescence flower pedicel , cotyledon , petiole , hypocotyl , leaf apex , collective leaf structure , pollen , plant sperm cell
Literature:
- The Arabidopsis Cks1At protein binds the cyclin-dependent kinases Cdc2aAt and Cdc2bAt. DOI: 10.1016/s0014-5793(97)00822-3 ; PMID: 9276444
- Genome-wide analysis of core cell cycle genes in Arabidopsis. DOI: 10.1105/tpc.010445 ; PMID: 11971144
- a high-density colony array study (HDCA). DOI: 10.1046/j.1365-313x.2003.01847.x ; PMID: 12969430
- Generation of Arabidopsis protein chips for antibody and serum screening. DOI: 10.1023/a:1025424814739 ; PMID: 14558660
- Gene family analysis of the Arabidopsis pollen transcriptome reveals biological implications for cell growth, division control, and gene expression regulation. DOI: 10.1104/pp.104.057935 ; PMID: 15908605
- A transcriptome-based characterization of habituation in plant tissue culture. DOI: 10.1104/pp.105.076059 ; PMID: 16489130
- A tandem affinity purification-based technology platform to study the cell cycle interactome in Arabidopsis thaliana. DOI: 10.1074/mcp.M700078-MCP200 ; PMID: 17426018
- Gene expression profiling of the different stages of Arabidopsis thaliana trichome development on the single cell level. DOI: 10.1016/j.plaphy.2007.11.001 ; PMID: 18160300
- Requirement of B2-type cyclin-dependent kinases for meristem integrity in Arabidopsis thaliana. DOI: 10.1105/tpc.107.054676 ; PMID: 18223038
- The transcriptional repressor ARR1-SRDX suppresses pleiotropic cytokinin activities in Arabidopsis. DOI: 10.1104/pp.107.115436 ; PMID: 18502977
- Systematic localization of the Arabidopsis core cell cycle proteins reveals novel cell division complexes. DOI: 10.1104/pp.109.148643 ; PMID: 20018602
- Targeted interactomics reveals a complex core cell cycle machinery in Arabidopsis thaliana. DOI: 10.1038/msb.2010.53 ; PMID: 20706207
- Recombinant production of the p10CKS1At protein from Arabidopsis thaliana and 13C and 15N double-isotopic enrichment for NMR studies. DOI: 10.1006/prep.1999.1056 ; PMID: 10336872
- Expression of CKS1At in Arabidopsis thaliana indicates a role for the protein in both the mitotic and the endoreduplication cycle. DOI: 10.1007/s004250050509 ; PMID: 10093894
- CKS1At overexpression in Arabidopsis thaliana inhibits growth by reducing meristem size and inhibiting cell-cycle progression. DOI: 10.1046/j.1365-313x.2001.00996.x ; PMID: 11319029
- Identification of novel cyclin-dependent kinases interacting with the CKS1 protein of Arabidopsis. DOI: NA ; PMID: 11432958
- Global analysis of the core cell cycle regulators of Arabidopsis identifies novel genes, reveals multiple and highly specific profiles of expression and provides a coherent model for plant cell cycle control. DOI: 10.1111/j.1365-313X.2004.02319.x ; PMID: 15686519
- Cyclin-dependent kinase inhibitors in maize endosperm and their potential role in endoreduplication. DOI: 10.1104/pp.105.063917 ; PMID: 16055680
- A tandem affinity purification-based technology platform to study the cell cycle interactome in Arabidopsis thaliana. DOI: 10.1074/mcp.M700078-MCP200 ; PMID: 17426018
Sequences:
cDNA Sequence
- >AT2G27960.1
CACCCAATTTCAATTCATTTTGGTAACTAACCGGTTTATAATCATTCATACCCAATCGGCGTCTTCTAAAGAATTTCAAAACTCTAAAAAGTTAATCAAACACCCCTCTATTTCCTCATAATTACATATCTACCCCAAACCACTTTATTCTCCTTTCACTATCTTCCCCAAATTTCAAACGATCAGATTACAGATTCTTCAATTCCTCTTTCCCTTCTCCTCCATTTCCTGATTAAGGCTTCACATCTCTGAGAGAGAAATGGGTCAGATCCAATACTCCGAGAAATACTTCGATGACACTTTCGAATACAGGCACGTCGTTCTTCCTCCTGAAGTCGCTAAACTTCTTCCAAAGAATCGTCTTCTCTCCGAAAACGAATGGCGAGCGATAGGAGTGCAGCAAAGCCGCGGATGGGTACATTACGCGGTTCATCGACCTGAGCCGCACATAATGCTATTCAGGAGGCCTCTTAACTATCAGCAGCAGCAGGAGAATCAAGCTCAGAACATGCTTGTTAAGTGAATCATTATCATCACCTGAGTAAGAATGTTATATGCAACAATTCTATGAGTATTGGTTTATGTTTCTTGTAAACATGGTTTGAATCTTTGTGGTTATGGATGAATATGTGAGAGTTGGTTTGTTGAACAACTTCTATGTAATGTTAGTCTTGGTTCTAATGTCATCTTCTGCTTCTTAATTACTTATTTCTCAAGACATTTGGTGGTAGTTTAGTGTCATCCAACTATGTGTTTGATTTTTAGATATATTGGTAAAATGGTCACTGGATAGGCATGAGTAGTTGAGAACAATGTGTCCCATGTTTCCACTCAACCATGAACACAAATGAAAGAGA
CDS Sequence
- >AT2G27960.1
ATGGGTCAGATCCAATACTCCGAGAAATACTTCGATGACACTTTCGAATACAGGCACGTCGTTCTTCCTCCTGAAGTCGCTAAACTTCTTCCAAAGAATCGTCTTCTCTCCGAAAACGAATGGCGAGCGATAGGAGTGCAGCAAAGCCGCGGATGGGTACATTACGCGGTTCATCGACCTGAGCCGCACATAATGCTATTCAGGAGGCCTCTTAACTATCAGCAGCAGCAGGAGAATCAAGCTCAGAACATGCTTGTTAAGTGA
Protein Sequence
- >AT2G27960.1
MGQIQYSEKYFDDTFEYRHVVLPPEVAKLLPKNRLLSENEWRAIGVQQSRGWVHYAVHRPEPHIMLFRRPLNYQQQQENQAQNMLVK