Gene Details:

• Gene ID: AT2G27350
• Gene Symbol: OTLD1
• Gene Name: otubain-like deubiquitinase 1
• Description: OTU-like cysteine protease family protein;(source:Araport11)
• Description: Derives_from AT2G27350;(source:Araport11)
• TAIR Accession: locus:2039642
• Genome: Araport11_genome_release
• Species: Arabidopsis thaliana

Transcripts:

• AT2G27350.1     AT2G27350.2     AT2G27350.5     AT2G27350.4     AT2G27350.3     AT2G27350.6     AT2G27350.uORF1

Plant Ontology Annotations:

• PO:0000037  — shoot axis apex — ápice del epiblasto (epiblastema) (Spanish, exact), シュート頂、茎頂 (Japanese, exact)
• PO:0008019  — leaf lamina base — base de la lámina de la hoja (Spanish, exact), 葉身基部 (Japanese, exact)
• PO:0009005  — root — raíz (Spanish, exact), radices (exact, plural), radix (exact), 根 (Japanese, exact), aerial root (narrow), climbing root (narrow)
• PO:0009006  — shoot system — sistema de epiblasto (epiblastema) (Spanish, exact), シュート系、苗条系 (Japanese, exact), Poaceae crown (related), shoot (related), thalli (related), thallus (related), tree crown (narrow)
• PO:0009009  — plant embryo — embrión (Spanish, exact), 植物胚 (Japanese, exact), germ (related), embryo (broad)
• PO:0009025  — vascular leaf — foliage leaf (exact), hoja vascular (Spanish, exact), leaf, vascular (exact), vascular leaves (exact, plural), 維管束のある葉, または維管束植物の葉 (Japanese, exact), crozier (related), macrophyll (related), megaphyll (related), ascidia (narrow), ascidium (narrow), fiddlehead (narrow), frond (narrow), needle-like leaf (narrow), pitcher (narrow), pitcher blade (narrow), pitcher-blade (narrow), scale-like leaf (narrow), sterile frond (narrow), trophophyll (narrow)
• PO:0009029  — stamen — estambre (Spanish, exact), 雄蕊 (Japanese, exact), Poaceae stamen (narrow), Zea stamen (narrow)
• PO:0009031  — sepal — sépalo (Spanish, exact), がく片 (Japanese, exact)
• PO:0009046  — flower — flor (Spanish, exact), 花 (Japanese, exact), floret (related), Asteraceae floret (narrow), basal flower (narrow), double flower (narrow), hermaphrodite flower (narrow), monoclinous flower (narrow), perfect flower (narrow)
• PO:0009052  — inflorescence flower pedicel — 小花柄 (Japanese, related), pedicelo (Spanish, broad)
• PO:0020030  — cotyledon — cotiledón (Spanish, exact), seed leaf (exact), 子葉 (Japanese, exact)
• PO:0020038  — petiole — pecíolo (Spanish, exact), 葉柄 (Japanese, exact)
• PO:0020100  — hypocotyl — hipocótile (Spanish, exact), 胚軸 (Japanese, exact)
• PO:0020137  — leaf apex — ápice de la hoja (Spanish, exact), 葉先 (Japanese, exact), leaf lamina apex (narrow), phyllid apex (narrow)
• PO:0025022  — collective leaf structure — estructura colectiva de hoja (Spanish, exact), leaf series (exact), 葉が集まった構造 (Japanese, exact), leaf whorl (narrow), rosette (narrow), cycle (broad), verticil (broad)
• PO:0025281  — pollen — polen (Spanish, exact), pollen grain (exact), 花粉 (Japanese, exact)
• PO:0000084  — plant sperm cell — célula espermática o esperma (Spanish, exact), male gamete (exact), microgamete (exact), 植物精子細胞 (Japanese, exact), sperm nucleus (related), sperm cell (broad)
• PO:0025195  — pollen tube cell — célula del tubo polínico (Spanish, exact), 花粉管細胞 (Japanese, exact)

Gene Ontology:

• GO:0045893  — involved in — positive regulation of DNA-templated transcription
• GO:0042393  — enables — histone binding
• GO:0009507  — located in — chloroplast
• GO:0031491  — enables — nucleosome binding
• GO:0045892  — acts upstream of or within — negative regulation of DNA-templated transcription
• GO:0005515  — enables — protein binding
• GO:0045892  — involved in — negative regulation of DNA-templated transcription
• GO:0045814  — involved in — negative regulation of gene expression, epigenetic
• GO:1902275  — involved in — regulation of chromatin organization
• GO:0061578  — enables — K63-linked deubiquitinase activity
• GO:0005634  — located in — nucleus
• GO:0005737  — located in — cytoplasm
• GO:0040029  — involved in — epigenetic regulation of gene expression
• GO:0003682  — enables — chromatin binding
• GO:0016579  — involved in — protein deubiquitination
• GO:0004843  — enables — cysteine-type deubiquitinase activity
• GO:0045927  — involved in — positive regulation of growth

Function-related keywords:

• shoot axis apex ,  leaf lamina base ,  root ,  shoot system ,  plant embryo ,  vascular leaf ,  stamen ,  sepal ,  flower ,  inflorescence flower pedicel ,  cotyledon ,  petiole ,  hypocotyl ,  leaf apex ,  collective leaf structure ,  pollen ,  plant sperm cell ,  pollen tube cell ,  pollen

Literature:

• Cell cycle-regulated gene expression in Arabidopsis.   DOI:  10.1074/jbc.M207570200 ;  PMID:  12169696
• Transcriptome analyses show changes in gene expression to accompany pollen germination and tube growth in Arabidopsis.   DOI:  10.1104/pp.108.126375 ;  PMID:  18775970
• Involvement of KDM1C histone demethylase-OTLD1 otubain-like histone deubiquitinase complexes in plant gene repression.   DOI:  10.1073/pnas.1014030108 ;  PMID:  21690391
• The histone deubiquitinase OTLD1 targets euchromatin to regulate plant growth.   DOI:  10.1126/scisignal.aaf6767 ;  PMID:  27999174
• Activation of gene expression by histone deubiquitinase OTLD1.   DOI:  10.1080/15592294.2017.1348446 ;  PMID:  28703681
• Coordinate activation of a target gene by KDM1C histone demethylase and OTLD1 histone deubiquitinase in Arabidopsis.   DOI:  10.1080/15592294.2019.1603982 ;  PMID:  30964380
• Arabidopsis LSH10 transcription factor and OTLD1 histone deubiquitinase interact and transcriptionally regulate the same target genes.   DOI:  10.1038/s42003-023-04424-x ;  PMID:  36650214

Sequences: