Gene Details:

• Gene ID: AT2G27230
• Gene Symbol: LHW
• Gene Name: LONESOME HIGHWAY
• Description: transcription factor-like protein;(source:Araport11)
• Description: Derives_from AT2G27230;(source:Araport11)
• TAIR Accession: locus:2039580
• Genome: Araport11_genome_release
• Species: Arabidopsis thaliana

Transcripts:

• AT2G27230.1     AT2G27230.2     AT2G27230.uORF1

Plant Ontology Annotations:

• PO:0000026  — primary root tip — punta de la raíz primaria (Spanish, exact), 一次根端 (Japanese, exact)
• PO:0000084  — plant sperm cell — célula espermática o esperma (Spanish, exact), male gamete (exact), microgamete (exact), 植物精子細胞 (Japanese, exact), sperm nucleus (related), sperm cell (broad)

Gene Ontology:

• GO:0048364  — acts upstream of or within — root development
• GO:0042803  — enables — protein homodimerization activity
• GO:0010078  — acts upstream of or within — maintenance of root meristem identity
• GO:0010089  — acts upstream of or within — xylem development
• GO:0003700  — enables — DNA-binding transcription factor activity
• GO:0006355  — involved in — regulation of DNA-templated transcription
• GO:0006355  — acts upstream of or within — regulation of DNA-templated transcription
• GO:0010479  — acts upstream of or within — stele development
• GO:0045893  — acts upstream of or within — positive regulation of DNA-templated transcription
• GO:0005634  — located in — nucleus

Function-related keywords:

• primary root tip ,  plant sperm cell

Literature:

• Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.   DOI:  10.1126/science.290.5499.2105 ;  PMID:  11118137
• The basic helix-loop-helix transcription factor family in plants: a genome-wide study of protein structure and functional diversity.   DOI:  10.1093/molbev/msg088 ;  PMID:  12679534
• Update on the basic helix-loop-helix transcription factor gene family in Arabidopsis thaliana.   DOI:  10.1105/tpc.151140 ;  PMID:  14600211
• Transcriptional profile of the Arabidopsis root quiescent center.   DOI:  10.1105/tpc.105.031724 ;  PMID:  15937229
• Potent induction of Arabidopsis thaliana flowering by elevated growth temperature.   DOI:  10.1371/journal.pgen.0020106 ;  PMID:  16839183
• Regulation of the Arabidopsis root vascular initial population by LONESOME HIGHWAY.   DOI:  10.1242/dev.006296 ;  PMID:  17626058
• Identification of novel conserved peptide uORF homology groups in Arabidopsis and rice reveals ancient eukaryotic origin of select groups and preferential association with transcription factor-encoding genes.   DOI:  10.1186/1741-7007-5-32 ;  PMID:  17663791
• BAIUCAS: a novel BLAST-based algorithm for the identification of upstream open reading frames with conserved amino acid sequences and its application to the Arabidopsis thaliana genome.   DOI:  10.1093/bioinformatics/bts303 ;  PMID:  22618534
• Auxin-associated initiation of vascular cell differentiation by LONESOME HIGHWAY.   DOI:  10.1242/dev.087924 ;  PMID:  23362345
• Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.   DOI:  10.1186/1471-2229-13-229 ;  PMID:  24377444
• An atypical bHLH transcription factor regulates early xylem development downstream of auxin.   DOI:  10.1093/pcp/pct013 ;  PMID:  23359424
• A bHLH-Based Feedback Loop Restricts Vascular Cell Proliferation in Plants.   DOI:  10.1016/j.devcel.2015.10.022 ;  PMID:  26609958
• A bHLH complex activates vascular cell division via cytokinin action in root apical meristem.   DOI:  10.1016/j.cub.2014.07.050 ;  PMID:  25131670
• A Negative Feedback Loop Controlling bHLH Complexes Is Involved in Vascular Cell Division and Differentiation in the Root Apical Meristem.   DOI:  10.1016/j.cub.2015.10.051 ;  PMID:  26616019
• A Positive Feedback Loop Comprising LHW-TMO5 and Local Auxin Biosynthesis Regulates Initial Vascular Development in Arabidopsis Roots.   DOI:  10.1093/pcp/pcz156 ;  PMID:  31392340
• Evolution of vascular plants through redeployment of ancient developmental regulators.   DOI:  10.1073/pnas.1912470117 ;  PMID:  31874927
• Vascular transcription factors guide plant epidermal responses to limiting phosphate conditions.   DOI:  10.1126/science.aay4970 ;  PMID:  32943451
• bHLH heterodimer complex variations regulate cell proliferation activity in the meristems of Arabidopsis thaliana.   DOI:  10.1016/j.isci.2022.105364 ;  PMID:  36339262
• The transcription factor AtMYB12 is part of a feedback loop regulating cell division orientation in the root meristem vasculature.   DOI:  10.1093/jxb/erad020 ;  PMID:  36651677
• Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.   DOI:  10.1126/science.290.5499.2105 ;  PMID:  11118137
• The basic helix-loop-helix transcription factor family in plants: a genome-wide study of protein structure and functional diversity.   DOI:  10.1093/molbev/msg088 ;  PMID:  12679534

Sequences: