Gene Details:

• Gene ID: AT2G26150
• Gene Symbol: ATHSFA2, HSFA2
• Gene Name: heat shock transcription factor A2, heat shock transcription factor A2
• Description: heat shock transcription factor A2;(source:Araport11)
• TAIR Accession: locus:2057371
• Genome: Araport11_genome_release
• Species: Arabidopsis thaliana

Transcripts:

• AT2G26150.1     AT2G26150.2     AT2G26150.3     AT2G26150.4

Plant Ontology Annotations:

• PO:0009009  — plant embryo — embrión (Spanish, exact), 植物胚 (Japanese, exact), germ (related), embryo (broad)
• PO:0009029  — stamen — estambre (Spanish, exact), 雄蕊 (Japanese, exact), Poaceae stamen (narrow), Zea stamen (narrow)
• PO:0009052  — inflorescence flower pedicel — 小花柄 (Japanese, related), pedicelo (Spanish, broad)
• PO:0025281  — pollen — polen (Spanish, exact), pollen grain (exact), 花粉 (Japanese, exact)

Gene Ontology:

• GO:0071456  — acts upstream of or within — cellular response to hypoxia
• GO:0001666  — acts upstream of or within — response to hypoxia
• GO:0034620  — acts upstream of or within — cellular response to unfolded protein
• GO:0000976  — enables — transcription cis-regulatory region binding
• GO:0005515  — enables — protein binding
• GO:0010286  — involved in — heat acclimation
• GO:0045893  — involved in — positive regulation of DNA-templated transcription
• GO:0043565  — enables — sequence-specific DNA binding
• GO:0003700  — enables — DNA-binding transcription factor activity
• GO:0009408  — involved in — response to heat
• GO:0006357  — involved in — regulation of transcription by RNA polymerase II
• GO:0042542  — acts upstream of or within — response to hydrogen peroxide
• GO:0034605  — acts upstream of or within — cellular response to heat
• GO:0034605  — involved in — cellular response to heat
• GO:0045893  — acts upstream of or within — positive regulation of DNA-templated transcription
• GO:0006355  — involved in — regulation of DNA-templated transcription
• GO:0005634  — located in — nucleus
• GO:0009408  — acts upstream of or within — response to heat
• GO:0005634  — is active in — nucleus
• GO:1990841  — enables — promoter-specific chromatin binding
• GO:0000978  — enables — RNA polymerase II cis-regulatory region sequence-specific DNA binding

Function-related keywords:

• plant embryo ,  stamen ,  inflorescence flower pedicel ,  pollen

Literature:

• The Hsf world: classification and properties of plant heat stress transcription factors.   DOI:  10.1379/1466-1268(1996)001<0215:thwcap>2.3.co;2 ;  PMID:  9222607
• Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.   DOI:  10.1126/science.290.5499.2105 ;  PMID:  11118137
• Global and hormone-induced gene expression changes during shoot development in Arabidopsis.   DOI:  10.1105/tpc.006668 ;  PMID:  12417700
• The heat stress transcription factor HsfA2 serves as a regulatory amplifier of a subset of genes in the heat stress response in Arabidopsis.   DOI:  10.1007/s11103-005-5750-x ;  PMID:  16649111
• Arabidopsis heat shock transcription factor A2 as a key regulator in response to several types of environmental stress.   DOI:  10.1111/j.1365-313X.2006.02889.x ;  PMID:  17059409
• A heat-inducible transcription factor, HsfA2, is required for extension of acquired thermotolerance in Arabidopsis.   DOI:  10.1104/pp.106.091322 ;  PMID:  17085506
• Identification of 118 Arabidopsis transcription factor and 30 ubiquitin-ligase genes responding to chitin, a plant-defense elicitor.   DOI:  10.1094/MPMI-20-8-0900 ;  PMID:  17722694
• High-level overexpression of the Arabidopsis HsfA2 gene confers not only increased themotolerance but also salt/osmotic stress tolerance and enhanced callus growth.   DOI:  10.1093/jxb/erm184 ;  PMID:  17890230
• The transcriptional co-activator MBF1c is a key regulator of thermotolerance in Arabidopsis thaliana.   DOI:  10.1074/jbc.M709187200 ;  PMID:  18201973
• Galactinol and raffinose constitute a novel function to protect plants from oxidative damage.   DOI:  10.1104/pp.108.122465 ;  PMID:  18502973
• Functional analysis of an Arabidopsis transcription factor WRKY25 in heat stress.   DOI:  10.1007/s00299-008-0666-y ;  PMID:  19125253
• The cytosolic protein response as a subcomponent of the wider heat shock response in Arabidopsis.   DOI:  10.1105/tpc.108.062596 ;  PMID:  19244141
• Arabidopsis ROF1 (FKBP62) modulates thermotolerance by interacting with HSP90.1 and affecting the accumulation of HsfA2-regulated sHSPs.   DOI:  10.1111/j.1365-313X.2009.03878.x ;  PMID:  19366428
• Characterization of mitochondrial dynamics and subcellular localization of ROS reveal that HsfA2 alleviates oxidative damage caused by heat stress in Arabidopsis.   DOI:  10.1093/jxb/erp078 ;  PMID:  19342427
• AtHsfA2 modulates expression of stress responsive genes and enhances tolerance to heat and oxidative stress in Arabidopsis.   DOI:  10.1360/062005-119 ;  PMID:  16483133
• Analysis of the regulation of target genes by an Arabidopsis heat shock transcription factor, HsfA2.   DOI:  10.1271/bbb.80809 ;  PMID:  19352026
• Investigating the role of plant heat shock proteins during oxidative stress.   DOI:  10.4161/psb.3.10.6021 ;  PMID:  19704521
• The contribution of carbohydrates including raffinose family oligosaccharides and sugar alcohols to protection of plant cells from oxidative damage.   DOI:  10.4161/psb.6738 ;  PMID:  19704439
• Involvement of Arabidopsis ROF2 (FKBP65) in thermotolerance.   DOI:  10.1007/s11103-009-9561-3 ;  PMID:  19876748
• The heat-inducible transcription factor HsfA2 enhances anoxia tolerance in Arabidopsis.   DOI:  10.1104/pp.109.149815 ;  PMID:  20089772
• The 26S proteasome function and Hsp90 activity involved in the regulation of HsfA2 expression in response to oxidative stress.   DOI:  10.1093/pcp/pcq015 ;  PMID:  20147301
• Cytosol-localized heat shock factor-binding protein, AtHSBP, functions as a negative regulator of heat shock response by translocation to the nucleus and is required for seed development in Arabidopsis.   DOI:  10.1104/pp.109.151225 ;  PMID:  20388662
• Promoter specificity and interactions between early and late Arabidopsis heat shock factors.   DOI:  10.1007/s11103-010-9643-2 ;  PMID:  20458611
• Sumoylation of Arabidopsis heat shock factor A2 (HsfA2) modifies its activity during acquired thermotholerance.   DOI:  10.1007/s11103-010-9652-1 ;  PMID:  20521085
• The AP2/ERF transcription factor AtERF73/HRE1 modulates ethylene responses during hypoxia in Arabidopsis.   DOI:  10.1104/pp.111.172486 ;  PMID:  21398256
• Diversity in DNA recognition by heat shock transcription factors (HSFs) from model organisms.   DOI:  10.1016/j.febslet.2011.04.014 ;  PMID:  21510947
• HsfA1d and HsfA1e involved in the transcriptional regulation of HsfA2 function as key regulators for the Hsf signaling network in response to environmental stress.   DOI:  10.1093/pcp/pcr045 ;  PMID:  21471117
• Arabidopsis HsfB1 and HsfB2b act as repressors of the expression of heat-inducible Hsfs but positively regulate the acquired thermotolerance.   DOI:  10.1104/pp.111.179036 ;  PMID:  21908690
• Enhanced Y1H assays for Arabidopsis.   DOI:  10.1038/nmeth.1750 ;  PMID:  22037706
• Downregulation of chloroplast RPS1 negatively modulates nuclear heat-responsive expression of HsfA2 and its target genes in Arabidopsis.   DOI:  10.1371/journal.pgen.1002669 ;  PMID:  22570631
• Oxidative stress provokes distinct transcriptional responses in the stress-tolerant atr7 and stress-sensitive loh2 Arabidopsis thaliana mutants as revealed by multi-parallel quantitative real-time PCR analysis of ROS marker and antioxidant genes.   DOI:  10.1016/j.plaphy.2012.05.024 ;  PMID:  22710144
• Arabidopsis NAC transcription factor JUNGBRUNNEN1 affects thermomemory-associated genes and enhances heat stress tolerance in primed and unprimed conditions.   DOI:  10.4161/psb.22092 ;  PMID:  23073024
• Heat stress-induced BBX18 negatively regulates the thermotolerance in Arabidopsis.   DOI:  10.1007/s11033-012-2354-9 ;  PMID:  23238922
• A cyclic nucleotide-gated channel (CNGC16) in pollen is critical for stress tolerance in pollen reproductive development.   DOI:  10.1104/pp.112.206888 ;  PMID:  23370720
• An autoregulatory loop controlling Arabidopsis HsfA2 expression: role of heat shock-induced alternative splicing.   DOI:  10.1104/pp.112.205864 ;  PMID:  23503691
• Common and distinct functions of Arabidopsis class A1 and A2 heat shock factors in diverse abiotic stress responses and development.   DOI:  10.1104/pp.113.221168 ;  PMID:  23832625
• Subset of heat-shock transcription factors required for the early response of Arabidopsis to excess light.   DOI:  10.1073/pnas.1311632110 ;  PMID:  23918368
• Four distinct types of dehydration stress memory genes in Arabidopsis thaliana.   DOI:  10.1186/1471-2229-13-229 ;  PMID:  24377444
• A seed preferential heat shock transcription factor from wheat provides abiotic stress tolerance and yield enhancement in transgenic Arabidopsis under heat stress environment.   DOI:  10.1371/journal.pone.0079577 ;  PMID:  24265778
• Histone chaperone ASF1 is involved in gene transcription activation in response to heat stress in Arabidopsis thaliana.   DOI:  10.1111/pce.12299 ;  PMID:  24548003
• A homolog of splicing factor SF1 is essential for development and is involved in the alternative splicing of pre-mRNA in Arabidopsis thaliana.   DOI:  10.1111/tpj.12491 ;  PMID:  24580679
• Arabidopsis miR156 Regulates Tolerance to Recurring Environmental Stress through SPL Transcription Factors.   DOI:  10.1105/tpc.114.123851 ;  PMID:  24769482
• An Arabidopsis gene regulatory network for secondary cell wall synthesis.   DOI:  10.1038/nature14099 ;  PMID:  25533953
• Reactive short-chain leaf volatiles act as powerful inducers of abiotic stress-related gene expression.   DOI:  10.1038/srep08030 ;  PMID:  25619826
• The impact of heat stress targeting on the hormonal and transcriptomic response in Arabidopsis.   DOI:  10.1016/j.plantsci.2014.11.005 ;  PMID:  25575991
• Melatonin induces class A1 heat-shock factors (HSFA1s) and their possible involvement of thermotolerance in Arabidopsis.   DOI:  10.1111/jpi.12219 ;  PMID:  25711624
• Accumulation of extra-chloroplastic triacylglycerols in Arabidopsis seedlings during heat acclimation.   DOI:  10.1093/jxb/erv226 ;  PMID:  25977236
• A Potential Role for Mitochondrial Produced Reactive Oxygen Species in Salicylic Acid-Mediated Plant Acquired Thermotolerance.   DOI:  10.1104/pp.15.00719 ;  PMID:  26099269
• Loss of Arabidopsis 5'-3' Exoribonuclease AtXRN4 Function Enhances Heat Stress Tolerance of Plants Subjected to Severe Heat Stress.   DOI:  10.1093/pcp/pcv096 ;  PMID:  26136597
• Histone acetyltransferase GCN5 is essential for heat stress-responsive gene activation and thermotolerance in Arabidopsis.   DOI:  10.1111/tpj.13076 ;  PMID:  26576681
• HSFA2 orchestrates transcriptional dynamics after heat stress in Arabidopsis thaliana.   DOI:  10.1080/21541264.2016.1187550 ;  PMID:  27383578
• Molecular regulation and physiological functions of a novel FaHsfA2c cloned from tall fescue conferring plant tolerance to heat stress.   DOI:  10.1111/pbi.12609 ;  PMID:  27500592
• Transcriptional Regulation of Arabidopsis Polycomb Repressive Complex 2 Coordinates Cell-Type Proliferation and Differentiation.   DOI:  10.1105/tpc.15.00744 ;  PMID:  27650334
• Identification of core subunits of photosystem II as action sites of HSP21, which is activated by the GUN5-mediated retrograde pathway in Arabidopsis.   DOI:  10.1111/tpj.13447 ;  PMID:  27943531
• Coordination between bZIP28 and HSFA2 in the regulation of heat response signals in Arabidopsis.   DOI:  10.1080/15592324.2017.1376159 ;  PMID:  28873003
• Up-Regulation of HSFA2c and HSPs by ABA Contributing to Improved Heat Tolerance in Tall Fescue and Arabidopsis.   DOI:  10.3390/ijms18091981 ;  PMID:  28914758
• Interference with plastome gene expression and Clp protease activity in Arabidopsis triggers a chloroplast unfolded protein response to restore protein homeostasis.   DOI:  10.1371/journal.pgen.1007022 ;  PMID:  28937985
• Plastid Translation Elongation Factor Tu Is Prone to Heat-Induced Aggregation Despite Its Critical Role in Plant Heat Tolerance.   DOI:  10.1104/pp.17.01672 ;  PMID:  29444814
• The roles of Arabidopsis HSFA2, HSFA4a, and HSFA7a in the heat shock response and cytosolic protein response.   DOI:  10.1186/s40529-018-0231-0 ;  PMID:  29785454
• NPR1 mediates a novel regulatory pathway in cold acclimation by interacting with HSFA1 factors.   DOI:  10.1038/s41477-018-0254-2 ;  PMID:  30250280
• SENSITIVE TO SALT1, An Endoplasmic Reticulum-Localized Chaperone, Positively Regulates Salt Resistance.   DOI:  10.1104/pp.18.00840 ;  PMID:  30287478
• An H3K27me3 demethylase-HSFA2 regulatory loop orchestrates transgenerational thermomemory in Arabidopsis.   DOI:  10.1038/s41422-019-0145-8 ;  PMID:  30778176
• STOP1 regulates the expression of HsfA2 and GDHs that are critical for low-oxygen tolerance in Arabidopsis.   DOI:  10.1093/jxb/erz124 ;  PMID:  30882866
• Transcriptional regulation of nitrogen-associated metabolism and growth.   DOI:  10.1038/s41586-018-0656-3 ;  PMID:  30356219
• Integrative Analysis from the Epigenome to Translatome Uncovers Patterns of Dominant Nuclear Regulation during Transient Stress.   DOI:  10.1105/tpc.19.00463 ;  PMID:  31519798
• A PXY-Mediated Transcriptional Network Integrates Signaling Mechanisms to Control Vascular Development in Arabidopsis.   DOI:  10.1105/tpc.19.00562 ;  PMID:  31806676
• An RNA thermoswitch regulates daytime growth in Arabidopsis.   DOI:  10.1038/s41477-020-0633-3 ;  PMID:  32284544
• AtHsc70-1 negatively regulates the basal heat tolerance in Arabidopsis thaliana through affecting the activity of HsfAs and Hsp101.   DOI:  10.1111/tpj.14883 ;  PMID:  32573848
• A novel seed plants gene regulates oxidative stress tolerance in Arabidopsis thaliana.   DOI:  10.1007/s00018-019-03202-5 ;  PMID:  31250033
• FORGETTER2 protein phosphatase and phospholipase D modulate heat stress memory in Arabidopsis.   DOI:  10.1111/tpj.14927 ;  PMID:  32654320
• Selective autophagy regulates heat stress memory in Arabidopsis by NBR1-mediated targeting of HSP90.1 and ROF1.   DOI:  10.1080/15548627.2020.1820778 ;  PMID:  32967551
• Two interacting ethylene response factors regulate heat stress response.   DOI:  10.1093/plcell/koaa026 ;  PMID:  33793870
• The Seed Development Factors TT2 and MYB5 Regulate Heat Stress Response in Arabidopsis.   DOI:  10.3390/genes12050746 ;  PMID:  34063415
• Heteromeric HSFA2/HSFA3 complexes drive transcriptional memory after heat stress in Arabidopsis.   DOI:  10.1038/s41467-021-23786-6 ;  PMID:  34103516
• DRD1, a SWI/SNF-like chromatin remodeling protein, regulates a heat-activated transposon in Arabidopsis thaliana.   DOI:  10.1266/ggs.21-00005 ;  PMID:  34373369
• Potassium transporter TRH1/KUP4 contributes to distinct auxin-mediated root system architecture responses.   DOI:  10.1093/plphys/kiab472 ;  PMID:  34633458
• A nitric oxide burst at the shoot apex triggers a heat-responsive pathway in Arabidopsis.   DOI:  10.1038/s41477-022-01135-9 ;  PMID:  35437002
• PIF4 Promotes Expression of HSFA2 to Enhance Basal Thermotolerance in Arabidopsis.   DOI:  10.3390/ijms23116017 ;  PMID:  35682701
• Heat shock factor HSFA2 fine-tunes resetting of thermomemory via plastidic metalloprotease FtsH6.   DOI:  10.1093/jxb/erac257 ;  PMID:  35705109
• HY5-HDA9 orchestrates the transcription of HsfA2 to modulate salt stress response in Arabidopsis.   DOI:  10.1111/jipb.13372 ;  PMID:  36165397
• BIIDXI, a DUF642 Cell Wall Protein That Regulates Pectin Methyl Esterase Activity, Is Involved in Thermotolerance Processes in Arabidopsis thaliana.   DOI:  10.3390/plants11223049 ;  PMID:  36432778
• The spliceophilin CYP18-2 is mainly involved in the splicing of retained introns under heat stress in Arabidopsis.   DOI:  10.1111/jipb.13450 ;  PMID:  36636802
• The miR165/166-PHABULOSA module promotes thermotolerance by transcriptionally and posttranslationally regulating HSFA1.   DOI:  10.1093/plcell/koad121 ;  PMID:  37132478
• Amomum tsaoko DRM1 regulate seed germination and improve heat tolerance in Arabidopsis.   DOI:  10.1016/j.jplph.2023.154007 ;  PMID:  37209458
• Nitric oxide working: no worries about heat stress.   DOI:  10.1016/j.tplants.2023.05.006 ;  PMID:  37270350
• Genomic and epigenomic determinants of heat stress-induced transcriptional memory in Arabidopsis.   DOI:  10.1186/s13059-023-02970-5 ;  PMID:  37254211
• Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes.   DOI:  10.1126/science.290.5499.2105 ;  PMID:  11118137
• Arabidopsis heat shock transcription factor A2 as a key regulator in response to several types of environmental stress.   DOI:  10.1111/j.1365-313X.2006.02889.x ;  PMID:  17059409
• Identification of 118 Arabidopsis transcription factor and 30 ubiquitin-ligase genes responding to chitin, a plant-defense elicitor.   DOI:  10.1094/MPMI-20-8-0900 ;  PMID:  17722694

Sequences: