Gene Details:
- Gene ID: AT2G26140
- Gene Symbol: AtFtsH4, ftsh4
- Gene Name: FTSH protease 4
- Description: FTSH protease 4;(source:Araport11)
- TAIR Accession: locus:2057386
- Genome: Araport11_genome_release
- Species: Arabidopsis thaliana
Transcripts:
Plant Ontology Annotations:
- PO:0009006 — shoot system — sistema de epiblasto (epiblastema) (Spanish, exact), シュート系、苗条系 (Japanese, exact), Poaceae crown (related), shoot (related), thalli (related), thallus (related), tree crown (narrow)
- PO:0009009 — plant embryo — embrión (Spanish, exact), 植物胚 (Japanese, exact), germ (related), embryo (broad)
- PO:0009029 — stamen — estambre (Spanish, exact), 雄蕊 (Japanese, exact), Poaceae stamen (narrow), Zea stamen (narrow)
- PO:0009052 — inflorescence flower pedicel — 小花柄 (Japanese, related), pedicelo (Spanish, broad)
- PO:0020030 — cotyledon — cotiledón (Spanish, exact), seed leaf (exact), 子葉 (Japanese, exact)
- PO:0020038 — petiole — pecíolo (Spanish, exact), 葉柄 (Japanese, exact)
- PO:0020100 — hypocotyl — hipocótile (Spanish, exact), 胚軸 (Japanese, exact)
- PO:0020137 — leaf apex — ápice de la hoja (Spanish, exact), 葉先 (Japanese, exact), leaf lamina apex (narrow), phyllid apex (narrow)
- PO:0025022 — collective leaf structure — estructura colectiva de hoja (Spanish, exact), leaf series (exact), 葉が集まった構造 (Japanese, exact), leaf whorl (narrow), rosette (narrow), cycle (broad), verticil (broad)
- PO:0025281 — pollen — polen (Spanish, exact), pollen grain (exact), 花粉 (Japanese, exact)
- PO:0025195 — pollen tube cell — célula del tubo polínico (Spanish, exact), 花粉管細胞 (Japanese, exact)
Gene Ontology:
- GO:0004176 — enables — ATP-dependent peptidase activity
- GO:0009534 — is active in — chloroplast thylakoid
- GO:0005739 — located in — mitochondrion
- GO:0010073 — acts upstream of or within — meristem maintenance
- GO:0006508 — involved in — proteolysis
- GO:0016887 — enables — ATP hydrolysis activity
- GO:0004222 — enables — metalloendopeptidase activity
Function-related keywords:
- shoot system , plant embryo , stamen , inflorescence flower pedicel , cotyledon , petiole , hypocotyl , leaf apex , collective leaf structure , pollen , pollen tube cell , pollen
Literature:
- Chloroplast and mitochondrial proteases in Arabidopsis. A proposed nomenclature. DOI: 10.1104/pp.125.4.1912 ; PMID: 11299370
- The gene complement for proteolysis in the cyanobacterium Synechocystis sp. PCC 6803 and Arabidopsis thaliana chloroplasts. DOI: 10.1007/s00294-002-0309-8 ; PMID: 12185496
- Coordinated regulation and complex formation of yellow variegated1 and yellow variegated2, chloroplastic FtsH metalloproteases involved in the repair cycle of photosystem II in Arabidopsis thylakoid membranes. DOI: 10.1105/tpc.017319 ; PMID: 14630971
- The Arabidopsis FtsH metalloprotease gene family: interchangeability of subunits in chloroplast oligomeric complexes. DOI: 10.1111/j.1365-313x.2003.02014.x ; PMID: 14996218
- Mapping the Arabidopsis organelle proteome. DOI: 10.1073/pnas.0506958103 ; PMID: 16618929
- Protease gene families in Populus and Arabidopsis. DOI: 10.1186/1471-2229-6-30 ; PMID: 17181860
- Membrane proteomic analysis of Arabidopsis thaliana using alternative solubilization techniques. DOI: 10.1021/pr060525b ; PMID: 17432890
- Contrasting patterns of transposable-element insertion polymorphism and nucleotide diversity in autotetraploid and allotetraploid Arabidopsis species. DOI: 10.1534/genetics.107.085761 ; PMID: 18493073
- Patterns of polymorphism and demographic history in natural populations of Arabidopsis lyrata. DOI: 10.1371/journal.pone.0002411 ; PMID: 18545707
- Transcriptome analyses show changes in gene expression to accompany pollen germination and tube growth in Arabidopsis. DOI: 10.1104/pp.108.126375 ; PMID: 18775970
- The lack of mitochondrial AtFtsH4 protease alters Arabidopsis leaf morphology at the late stage of rosette development under short-day photoperiod. DOI: 10.1111/j.1365-313X.2009.03907.x ; PMID: 19453455
- Plant mitochondria contain at least two i-AAA-like complexes. DOI: 10.1007/s11103-005-8766-3 ; PMID: 16247555
- Mitochondrial protease AtFtsH4 protects ageing Arabidopsis rosettes against oxidative damage under short-day photoperiod. DOI: 10.4161/psb.5.2.10303 ; PMID: 20009533
- ATP-dependent proteases in biogenesis and maintenance of plant mitochondria. DOI: 10.1016/j.bbabio.2010.02.027 ; PMID: 20193658
- FtsH proteases located in the plant chloroplast. DOI: 10.1111/j.1399-3054.2011.01548.x ; PMID: 22121866
- Two-step processing of AtFtsH4 precursor by mitochondrial processing peptidase in Arabidopsis thaliana. DOI: 10.1093/mp/sss099 ; PMID: 22986791
- Lack of FTSH4 Protease Affects Protein Carbonylation, Mitochondrial Morphology, and Phospholipid Content in Mitochondria of Arabidopsis: New Insights into a Complex Interplay. DOI: 10.1104/pp.16.00370 ; PMID: 27297677
- The mitochondrial protease AtFTSH4 safeguards Arabidopsis shoot apical meristem function. DOI: 10.1038/srep28315 ; PMID: 27321362
- Variable Cell Growth Yields Reproducible OrganDevelopment through Spatiotemporal Averaging. DOI: 10.1016/j.devcel.2016.06.016 ; PMID: 27404356
- AtFtsH4 perturbs the mitochondrial respiratory chain complexes and auxin homeostasis in Arabidopsis. DOI: 10.4161/psb.29709 ; PMID: 25763704
- The Arabidopsis Mitochondrial Protease FtSH4 Is Involved in Leaf Senescence via Regulation of WRKY-Dependent Salicylic Acid Accumulation and Signaling. DOI: 10.1104/pp.16.00008 ; PMID: 28250067
- Impairment of Meristem Proliferation in Plants Lacking the Mitochondrial Protease AtFTSH4. DOI: 10.3390/ijms19030853 ; PMID: 29538317
- Targeted Proteomics Approach Toward Understanding the Role of the Mitochondrial Protease FTSH4 in the Biogenesis of OXPHOS During Arabidopsis Seed Germination. DOI: 10.3389/fpls.2018.00821 ; PMID: 29963070
- FTSH4 and OMA1 mitochondrial proteases reduce moderate heat stress-induced protein aggregation. DOI: 10.1093/plphys/kiab296 ; PMID: 34608962
- Chloroplast and mitochondrial proteases in Arabidopsis. A proposed nomenclature. DOI: 10.1104/pp.125.4.1912 ; PMID: 11299370
- Mapping the Arabidopsis organelle proteome. DOI: 10.1073/pnas.0506958103 ; PMID: 16618929
- Membrane proteomic analysis of Arabidopsis thaliana using alternative solubilization techniques. DOI: 10.1021/pr060525b ; PMID: 17432890
Sequences:
cDNA Sequence
- >AT2G26140.1
TGCCAATTTATGTTCTAGGTCCTTCTTTTTAATGTGGGCCGCCAGAAAAAGCCTACTAAAATGAATTATTGGGTATGTCCAAGGGTATTTATGTACTTAAGAGGCGACCTACATATCTCGTGCGTGTCTCCACCTGCTGCACAATTTTTCTCTCACCCGATAACCAAACAGGTCTCTCACGTGTAATTTAGTGTTTTTAAGACTTTAGGGAATAAGATTAGAACGGTTCTTCCCCAAACACAACGAAGAAGTCTTTTGTTTCCGATATAGATCGAGGAACTTCGATTTATCAGACATTAACACCAATTTTTAAGATATCGTGAAGGAGAGATTTGATTGATGGCTTGGAGGCGCATCATCACCAAGGTTTCGAGTCATGAAAGGGAATTGAGCAGTTTAAGAAGCTTACTTGTTAGAGCTTACTCCTCTTTTCCTAGAGTGGGAGTTACTGGAGCTGTGGGTGGTGGTGGAGCTTCTTTACCGCGAACGAGGTTTCAATCGAGTTATGTTGGTAGCTTTGCTCGCAGAGTCCGTGATAGAGAAGAAGTTAATGAGGTTGCACATCTGAGAGAACTTATTCGAAGAAATGATCCTGAGGCTGTTATCAGAATGTTTGAAAGCCAACCTTCTTTGCATGCGAATGCCTCTGCGTTATCGGAATACATTAAGGCATTGGTTAAAGTTGATAGGCTCGATCAAAGTGAGCTGGTTCGAACATTGCAAAGAGGTATTGCTGGTGTTGCAAGGGAGGAAGAGACTTTTGGAGGTCTTGGGGCATTTAGAAACGTAGGAAAACCAACAAAAGATGGTGTCCTTGGAACTGCTAGTGCACCGATCCATACGATATCCACAGAAAGGACTCACTTTAAAGAACAGCTATGGAGTACAATCCGAACTATTGGAGTTGGTTTTTTACTCATTTCTGGTATTGGAGCTCTTATCGAGGACAGAGGAATTGGCAAAGGACTTGGTTTGCACGAAGAAGTGCAACCTAGTATGGATTCGAGCACCAAATTTTCTGATGTAAAGGGTGTTGATGAAGCAAAGGCTGAGCTAGAGGAAATTGTGCATTATCTTCGCGACCCCAAAAGGTTCACTCGTCTGGGAGGAAAGCTTCCTAAGGGTGTGTTGCTTGTCGGTCCTCCTGGGACAGGAAAAACTATGCTTGCTAGAGCTATTGCTGGAGAAGCTGGAGTGCCTTTCTTCTCCTGCAGTGGTAGTGAGTTTGAAGAGATGTTTGTTGGAGTTGGAGCCAGAAGAGTGAGAGATCTTTTTAGTGCTGCAAAGAAGTGCTCCCCGTGTATTATATTTATCGATGAAATAGATGCTATTGGAGGAAGTCGCAATCCCAAGGACCAGCAATACATGAAGATGACATTGAACCAGATGCTCGTTGAGTTGGATGGGTTTAAACAGAATGAAGGAATTATTGTGGTCGCAGCAACAAATTTCCCAGAGTCTTTGGATAAGGCCCTGGTTAGACCTGGGAGGTTTGATCGTCATATTGTTGTACCTAACCCAGACGTGGAAGGTCGACGCCAGATTTTGGAGTCTCACATGTCAAAGGTACTTAAGGCTGAAGATGTCGATTTAATGATCATCGCTAGAGGAACGCCTGGATTTTCTGGCGCTGATTTGGCTAATCTGGTCAATGTTGCTGCTTTAAAAGCTGCAATGGACGGTTCTAAAGATGTGACAATGTCTGATCTTGAGTTTGCCAAAGACAGAATCATGATGGGAAGTGAGAGGAAATCTGCAGTTATATCTGACGAGTCAAGAAAGCTAACTGCTTTCCATGAAGGTGGTCATGCCCTTGTTGCCATTCACACCGAAGGTGCTCTTCCAGTCCACAAAGCAACCATTGTGCCTCGTGGTATGGCTCTTGGCATGGTTTCTCAACTACCAGATAAAGATGAGACGAGCATTTCTAGGAAACAGATGCTTGCTAGGCTTGATGTTTGTATGGGAGGCCGGGTAGCCGAAGAGTTGATTTTTGGGGAAAGTGAAGTAACTTCGGGTGCATCTTCTGATCTTGAGCAGGCAACCAAACTCGCGAGAGCAATGGTCACGAAATTCGGTATGAGCAAAGAGGTGGGTCTTGTGGCACATAACTACGACGACAATGGGAAAAGCATGAGCACCGAGACAAGGCTTCTCATTGAGAGTGAAGTGAAACAACTTCTGGAAAAGGCTTATAACAATGCAAAAACAATCCTCACGGTTTACAACAAAGAGCTTCATGCCCTTGCAAATGCTTTGCTTCAGCACGAAACTCTGTCCGGTAAGCAGATTAAAGAATTGCTTACCGATCTCAACTCTCCACTGCTGCAAAAGCGTCAAGAAGTGGTTACAAAGCAAAGCAACCCGGTTCCTCCATCAACCCCTAGCTCAGCATCATCAGCAGCCGCAGCAGCTGCCGCAGCTGCAGCCGCCGCCGCCGCAGCAGCTGCAACAGCCGCAACCAAAGGTAAAGACATGGCGCCAGTATCGTAAAAATAAAGGAGCTAGCGTTTGGTAGAGAAGGCGTTTTCATGTATTTGTGTATGTTGGGGTAATTGAATTGGGAATAACTCTTTATTTTGAGAGTTTTTAGAATCAGTGAGAGGCTGGTGAGGGTTAAGAGCATTAAGCTTAGGACAATGAGATTAACATCTCAGGTTTTTCTCTATCTCTATCTCGTACACACGGAATCTCGCTGCGAAATGGTATGTGTTCACTTTTTCTCTAAATGTTTTCGGAATCTCGTGGGATGTTATTTAGAAGTTTGGCTCGTACAGTTTCAGGTTACACTAAATTCTAAAGCCTGCTTGTAAGACTCAATGCAATAAATTTTATAGTCTCTTGTTATTGGTCT
CDS Sequence
- >AT2G26140.1
ATGGCTTGGAGGCGCATCATCACCAAGGTTTCGAGTCATGAAAGGGAATTGAGCAGTTTAAGAAGCTTACTTGTTAGAGCTTACTCCTCTTTTCCTAGAGTGGGAGTTACTGGAGCTGTGGGTGGTGGTGGAGCTTCTTTACCGCGAACGAGGTTTCAATCGAGTTATGTTGGTAGCTTTGCTCGCAGAGTCCGTGATAGAGAAGAAGTTAATGAGGTTGCACATCTGAGAGAACTTATTCGAAGAAATGATCCTGAGGCTGTTATCAGAATGTTTGAAAGCCAACCTTCTTTGCATGCGAATGCCTCTGCGTTATCGGAATACATTAAGGCATTGGTTAAAGTTGATAGGCTCGATCAAAGTGAGCTGGTTCGAACATTGCAAAGAGGTATTGCTGGTGTTGCAAGGGAGGAAGAGACTTTTGGAGGTCTTGGGGCATTTAGAAACGTAGGAAAACCAACAAAAGATGGTGTCCTTGGAACTGCTAGTGCACCGATCCATACGATATCCACAGAAAGGACTCACTTTAAAGAACAGCTATGGAGTACAATCCGAACTATTGGAGTTGGTTTTTTACTCATTTCTGGTATTGGAGCTCTTATCGAGGACAGAGGAATTGGCAAAGGACTTGGTTTGCACGAAGAAGTGCAACCTAGTATGGATTCGAGCACCAAATTTTCTGATGTAAAGGGTGTTGATGAAGCAAAGGCTGAGCTAGAGGAAATTGTGCATTATCTTCGCGACCCCAAAAGGTTCACTCGTCTGGGAGGAAAGCTTCCTAAGGGTGTGTTGCTTGTCGGTCCTCCTGGGACAGGAAAAACTATGCTTGCTAGAGCTATTGCTGGAGAAGCTGGAGTGCCTTTCTTCTCCTGCAGTGGTAGTGAGTTTGAAGAGATGTTTGTTGGAGTTGGAGCCAGAAGAGTGAGAGATCTTTTTAGTGCTGCAAAGAAGTGCTCCCCGTGTATTATATTTATCGATGAAATAGATGCTATTGGAGGAAGTCGCAATCCCAAGGACCAGCAATACATGAAGATGACATTGAACCAGATGCTCGTTGAGTTGGATGGGTTTAAACAGAATGAAGGAATTATTGTGGTCGCAGCAACAAATTTCCCAGAGTCTTTGGATAAGGCCCTGGTTAGACCTGGGAGGTTTGATCGTCATATTGTTGTACCTAACCCAGACGTGGAAGGTCGACGCCAGATTTTGGAGTCTCACATGTCAAAGGTACTTAAGGCTGAAGATGTCGATTTAATGATCATCGCTAGAGGAACGCCTGGATTTTCTGGCGCTGATTTGGCTAATCTGGTCAATGTTGCTGCTTTAAAAGCTGCAATGGACGGTTCTAAAGATGTGACAATGTCTGATCTTGAGTTTGCCAAAGACAGAATCATGATGGGAAGTGAGAGGAAATCTGCAGTTATATCTGACGAGTCAAGAAAGCTAACTGCTTTCCATGAAGGTGGTCATGCCCTTGTTGCCATTCACACCGAAGGTGCTCTTCCAGTCCACAAAGCAACCATTGTGCCTCGTGGTATGGCTCTTGGCATGGTTTCTCAACTACCAGATAAAGATGAGACGAGCATTTCTAGGAAACAGATGCTTGCTAGGCTTGATGTTTGTATGGGAGGCCGGGTAGCCGAAGAGTTGATTTTTGGGGAAAGTGAAGTAACTTCGGGTGCATCTTCTGATCTTGAGCAGGCAACCAAACTCGCGAGAGCAATGGTCACGAAATTCGGTATGAGCAAAGAGGTGGGTCTTGTGGCACATAACTACGACGACAATGGGAAAAGCATGAGCACCGAGACAAGGCTTCTCATTGAGAGTGAAGTGAAACAACTTCTGGAAAAGGCTTATAACAATGCAAAAACAATCCTCACGGTTTACAACAAAGAGCTTCATGCCCTTGCAAATGCTTTGCTTCAGCACGAAACTCTGTCCGGTAAGCAGATTAAAGAATTGCTTACCGATCTCAACTCTCCACTGCTGCAAAAGCGTCAAGAAGTGGTTACAAAGCAAAGCAACCCGGTTCCTCCATCAACCCCTAGCTCAGCATCATCAGCAGCCGCAGCAGCTGCCGCAGCTGCAGCCGCCGCCGCCGCAGCAGCTGCAACAGCCGCAACCAAAGGTAAAGACATGGCGCCAGTATCGTAA
Protein Sequence
- >AT2G26140.1
MAWRRIITKVSSHERELSSLRSLLVRAYSSFPRVGVTGAVGGGGASLPRTRFQSSYVGSFARRVRDREEVNEVAHLRELIRRNDPEAVIRMFESQPSLHANASALSEYIKALVKVDRLDQSELVRTLQRGIAGVAREEETFGGLGAFRNVGKPTKDGVLGTASAPIHTISTERTHFKEQLWSTIRTIGVGFLLISGIGALIEDRGIGKGLGLHEEVQPSMDSSTKFSDVKGVDEAKAELEEIVHYLRDPKRFTRLGGKLPKGVLLVGPPGTGKTMLARAIAGEAGVPFFSCSGSEFEEMFVGVGARRVRDLFSAAKKCSPCIIFIDEIDAIGGSRNPKDQQYMKMTLNQMLVELDGFKQNEGIIVVAATNFPESLDKALVRPGRFDRHIVVPNPDVEGRRQILESHMSKVLKAEDVDLMIIARGTPGFSGADLANLVNVAALKAAMDGSKDVTMSDLEFAKDRIMMGSERKSAVISDESRKLTAFHEGGHALVAIHTEGALPVHKATIVPRGMALGMVSQLPDKDETSISRKQMLARLDVCMGGRVAEELIFGESEVTSGASSDLEQATKLARAMVTKFGMSKEVGLVAHNYDDNGKSMSTETRLLIESEVKQLLEKAYNNAKTILTVYNKELHALANALLQHETLSGKQIKELLTDLNSPLLQKRQEVVTKQSNPVPPSTPSSASSAAAAAAAAAAAAAAAAATAATKGKDMAPVS