Gene Details:

• Gene ID: AT1G05180
• Gene Symbol: AXR1
• Gene Name: AUXIN RESISTANT 1
• Description: NAD(P)-binding Rossmann-fold superfamily protein;(source:Araport11)
• TAIR Accession: locus:2207220
• Genome: Araport11_genome_release
• Species: Arabidopsis thaliana

Transcripts:

• AT1G05180.1     AT1G05180.2     AT1G05180.3

Plant Ontology Annotations:

• PO:0000013  — cauline leaf — hoja caulinar (Spanish, exact), 茎生葉、茎葉 (Japanese, exact)
• PO:0000230  — inflorescence meristem — meristema de la inflorescencia (Spanish, exact), 花序分裂組織 (Japanese, exact)
• PO:0009010  — seed — semilla (Spanish, exact), 種子 (Japanese, exact), pyrene (narrow), diaspore (broad)
• PO:0009030  — carpel — carpelo (Spanish, exact), 心皮 (Japanese, exact), Poaceae carpel (narrow), Zea carpel (narrow), pistil (broad)
• PO:0009032  — petal — pétalo (Spanish, exact), 花弁 (Japanese, exact)
• PO:0009047  — stem — caña (Spanish, exact), culm (exact), eje primario (Spanish, exact), primary axis (exact), primary stem (exact), tallo (Spanish, exact), tronco (Spanish, exact), 茎 (Japanese, exact), bole (narrow), cane (narrow), caudex (narrow), caudices (narrow), core (narrow), primocane (narrow), scape (narrow), stalk (narrow), trunk (narrow)
• PO:0025281  — pollen — polen (Spanish, exact), pollen grain (exact), 花粉 (Japanese, exact)
• PO:0000293  — guard cell — célula guardiana (Spanish, exact), occlusive cell (exact), 孔辺細胞 (Japanese, exact)

Gene Ontology:

• GO:0009414  — acts upstream of or within — response to water deprivation
• GO:0009965  — acts upstream of or within — leaf morphogenesis
• GO:0006281  — acts upstream of or within — DNA repair
• GO:0009734  — acts upstream of or within — auxin-activated signaling pathway
• GO:0007131  — involved in — reciprocal meiotic recombination
• GO:0005886  — located in — plasma membrane
• GO:0005634  — located in — nucleus
• GO:0019781  — enables — NEDD8 activating enzyme activity
• GO:0005737  — is active in — cytoplasm
• GO:0009735  — acts upstream of or within — response to cytokinin
• GO:0005515  — enables — protein binding
• GO:0008641  — enables — ubiquitin-like modifier activating enzyme activity

Function-related keywords:

• cauline leaf ,  inflorescence meristem ,  seed ,  carpel ,  petal ,  stem ,  pollen ,  guard cell

Literature:

• A chloroplast-localized mitochondrial calcium uniporter transduces osmotic stress in Arabidopsis.   DOI:  10.1038/s41477-019-0434-8 ;  PMID:  31182842
• MYB30 Is a Key Negative Regulator of Arabidopsis Photomorphogenic Development That Promotes PIF4 and PIF5 Protein Accumulation in the Light.   DOI:  10.1105/tpc.19.00645 ;  PMID:  32371543
• The coordination of guard-cell autonomous ABA synthesis and DES1 function in situ regulates plant water deficit responses.   DOI:  10.1016/j.jare.2020.07.013 ;  PMID:  33318877
• Guard-cell phytochromes impact seedling photomorphogenesis and rosette leaf morphology.   DOI:  10.17912/micropub.biology.000521 ;  PMID:  35128344
• Arabidopsis R2R3-MYB transcription factor AtMYB60 functions as a transcriptional repressor of anthocyanin biosynthesis in lettuce (Lactuca sativa).   DOI:  10.1007/s00299-008-0521-1 ;  PMID:  18317777
• Characterization of plant proteins that interact with cowpea mosaic virus '60K' protein in the yeast two-hybrid system.   DOI:  10.1099/0022-1317-83-4-885 ;  PMID:  11907339
• Superoxide dismutase in Arabidopsis: an eclectic enzyme family with disparate regulation and protein localization.   DOI:  10.1104/pp.118.2.637 ;  PMID:  9765550
• cDNA and derived amino acid sequence of a cytosolic Cu,Zn superoxide dismutase from Arabidopsis thaliana (L.) Heyhn.   DOI:  10.1007/BF00018463 ;  PMID:  1731963
• A custom microarray analysis of gene expression during programmed cell death in Arabidopsis thaliana.   DOI:  10.1046/j.1365-313x.2002.01301.x ;  PMID:  12028573
• Two P-type ATPases are required for copper delivery in Arabidopsis thaliana chloroplasts.   DOI:  10.1105/tpc.104.030452 ;  PMID:  15772282
• Posttranscriptional induction of two Cu/Zn superoxide dismutase genes in Arabidopsis is mediated by downregulation of miR398 and important for oxidative stress tolerance.   DOI:  10.1105/tpc.106.041673 ;  PMID:  16861386
• Long-term effects of mild salt stress on growth, ion accumulation and superoxide dismutase expression of Arabidopsis rosette leaves.   DOI:  10.1111/j.1399-3054.2007.01009.x ;  PMID:  18275461
• Sucrose induction of Arabidopsis miR398 represses two Cu/Zn superoxide dismutases.   DOI:  10.1007/s11103-008-9329-1 ;  PMID:  18392778
• Contribution of plastocyanin isoforms to photosynthesis and copper homeostasis in Arabidopsis thaliana grown at different copper regimes.   DOI:  10.1007/s00425-008-0869-z ;  PMID:  19084994
• Biotic and abiotic stress down-regulate miR398 expression in Arabidopsis.   DOI:  10.1007/s00425-009-0889-3 ;  PMID:  19148671
• Differential and dynamic regulation of miR398 in response to ABA and salt stress in Populus tremula and Arabidopsis thaliana.   DOI:  10.1007/s11103-009-9508-8 ;  PMID:  19533381
• microRNA-directed cleavage and translational repression of the copper chaperone for superoxide dismutase mRNA in Arabidopsis.   DOI:  10.1111/j.1365-313X.2010.04162.x ;  PMID:  20128885
• Effect of Cu content on the activity of Cu/ZnSOD1 in the Arabidopsis SUMO E3 ligase siz1 mutant.   DOI:  10.4161/psb.6.10.16933 ;  PMID:  21897129
• Copper chaperone-dependent and -independent activation of three copper-zinc superoxide dismutase homologs localized in different cellular compartments in Arabidopsis.   DOI:  10.1104/pp.111.190223 ;  PMID:  22186608
• AtACDO1, an ABC1-like kinase gene, is involved in chlorophyll degradation and the response to photooxidative stress in Arabidopsis.   DOI:  10.1093/jxb/ers072 ;  PMID:  22447966
• Heat stress induction of miR398 triggers a regulatory loop that is critical for thermotolerance in Arabidopsis.   DOI:  10.1111/tpj.12169 ;  PMID:  23480361
• MKK5 regulates high light-induced gene expression of Cu/Zn superoxide dismutase 1 and 2 in Arabidopsis.   DOI:  10.1093/pcp/pct072 ;  PMID:  23677921
• The CTR/COPT-dependent copper uptake and SPL7-dependent copper deficiency responses are required for basal cadmium tolerance in A. thaliana.   DOI:  10.1039/c3mt00111c ;  PMID:  23835944
• Cytosolic BolA Plays a Repressive Role in the Tolerance against Excess Iron and MV-Induced Oxidative Stress in Plants.   DOI:  10.1371/journal.pone.0124887 ;  PMID:  25928219
• miR408 is involved in abiotic stress responses in Arabidopsis.   DOI:  10.1111/tpj.12999 ;  PMID:  26312768
• Importance of the alternative oxidase (AOX) pathway in regulating cellular redox and ROS homeostasis to optimize photosynthesis during restriction of the cytochrome oxidase pathway in Arabidopsis thaliana.   DOI:  10.1093/aob/mcv122 ;  PMID:  26292995
• Oxidative stress responses induced by uranium exposure at low pH in leaves of Arabidopsis thaliana plants.   DOI:  10.1016/j.jenvrad.2015.07.021 ;  PMID:  26263174
• Oxidative stress associated with rootstock-scion interactions in pear/quince combinations during early stages of graft development.   DOI:  10.1016/j.jplph.2014.10.015 ;  PMID:  25543953
• A New Anti-Aging Lysophosphatidic Acid from Arabidopsis thaliana.   DOI:  10.2174/1573406413666170209124934 ;  PMID:  28185536
• miR398 and miR395 are involved in response to SO(2) stress in Arabidopsis thaliana.   DOI:  10.1007/s10646-017-1843-y ;  PMID:  28819808
• SPL7 locally regulates copper-homeostasis-related genes in Arabidopsis.   DOI:  10.1016/j.jplph.2018.03.014 ;  PMID:  29635212
• The Zinc-Finger Thylakoid-Membrane Protein FIP Is Involved With Abiotic Stress Response in Arabidopsis thaliana.   DOI:  10.3389/fpls.2018.00504 ;  PMID:  29720990
• Fumarylacetoacetate hydrolase is involved in salt stress response in Arabidopsis.   DOI:  10.1007/s00425-018-2907-9 ;  PMID:  29785518
• The mitochondrial copper chaperone COX19 influences copper and iron homeostasis in arabidopsis.   DOI:  10.1007/s11103-019-00840-y ;  PMID:  30778722
• SQUAMOSA promoter-binding protein-like 7 mediates copper deficiency response in the presence of high nitrogen in Arabidopsis thaliana.   DOI:  10.1007/s00299-019-02422-0 ;  PMID:  31093688
• 24-Epibrassinolide promotes arsenic tolerance in Arabidopsis thaliana L. by altering stress responses at biochemical and molecular level.   DOI:  10.1016/j.jplph.2019.05.002 ;  PMID:  31121523
• GSM2, a transaldolase, contributes to reactive oxygen species homeostasis in Arabidopsis.   DOI:  10.1007/s11103-020-01022-x ;  PMID:  32564178
• Overexpression mutants reveal a role for a chloroplast MPD protein in regulation of reactive oxygen species during chilling in Arabidopsis.   DOI:  10.1093/jxb/erac029 ;  PMID:  35084440
• miR398b and AtC2GnT form a negative feedback loop to regulate Arabidopsis thaliana resistance against Phytophthora parasitica.   DOI:  10.1111/tpj.15792 ;  PMID:  35506331
• A DNA2 Homolog Is Required for DNA Damage Repair, Cell Cycle Regulation, and Meristem Maintenance in Plants.   DOI:  10.1104/pp.16.00312 ;  PMID:  26951435
• Secondary Mutation-Induced Alternative Splicing Suppresses RNA Splicing Defect of the jhs1 Mutant.   DOI:  10.1104/pp.19.01571 ;  PMID:  32054782
• Developmentally regulated HEART STOPPER, a mitochondrially targeted L18 ribosomal protein gene, is required for cell division, differentiation, and seed development in Arabidopsis.   DOI:  10.1093/jxb/erv296 ;  PMID:  26105995
• Rerouting of ribosomal proteins into splicing in plant organelles.   DOI:  10.1073/pnas.2004075117 ;  PMID:  33168708
• The BON/CPN gene family represses cell death and promotes cell growth in Arabidopsis.   DOI:  10.1111/j.1365-313X.2005.02585.x ;  PMID:  16367962
• Multiple R-like genes are negatively regulated by BON1 and BON3 in arabidopsis.   DOI:  10.1094/MPMI-22-7-0840 ;  PMID:  19522566
• Opposing Effects on Two Phases of Defense Responses from Concerted Actions of HEAT SHOCK COGNATE70 and BONZAI1 in Arabidopsis.   DOI:  10.1104/pp.15.00970 ;  PMID:  26408532
• Plasma Membrane-Localized Calcium Pumps and Copines Coordinately Regulate Pollen Germination and Fertility in Arabidopsis.   DOI:  10.3390/ijms19061774 ;  PMID:  29914054
• Ionizing radiation-dependent gamma-H2AX focus formation requires ataxia telangiectasia mutated and ataxia telangiectasia mutated and Rad3-related.   DOI:  10.1091/mbc.e04-10-0890 ;  PMID:  15772150
• Locus-specific control of DNA methylation by the Arabidopsis SUVH5 histone methyltransferase.   DOI:  10.1105/tpc.106.041400 ;  PMID:  16582009
• Constitutive expression exposes functional redundancy between the Arabidopsis histone H2A gene HTA1 and other H2A gene family members.   DOI:  10.1105/tpc.105.039719 ;  PMID:  16751347
• Repression of flowering in Arabidopsis requires activation of FLOWERING LOCUS C expression by the histone variant H2A.Z.   DOI:  10.1105/tpc.106.048447 ;  PMID:  17220196
• ASY1 mediates AtDMC1-dependent interhomolog recombination during meiosis in Arabidopsis.   DOI:  10.1101/gad.439007 ;  PMID:  17785529
• Xrcc1-dependent and Ku-dependent DNA double-strand break repair kinetics in Arabidopsis plants.   DOI:  10.1111/j.1365-313X.2010.04331.x ;  PMID:  21070408
• The Transcriptional Coactivator ADA2b Recruits a Structural Maintenance Protein to Double-Strand Breaks during DNA Repair in Plants.   DOI:  10.1104/pp.18.00123 ;  PMID:  29463775
• Responsiveness of Early Response to Dehydration Six-Like Transporter Genes to Water Deficit in Arabidopsis thaliana Leaves.   DOI:  10.3389/fpls.2021.708876 ;  PMID:  34484269
• Molecular cloning and characterization of an amidase from Arabidopsis thaliana capable of converting indole-3-acetamide into the plant growth hormone, indole-3-acetic acid.   DOI:  10.1016/s0031-9422(02)00563-0 ;  PMID:  12620340
• Genome-wide gene expression in an Arabidopsis cell suspension.   DOI:  10.1023/B:PLAN.0000019059.56489.ca ;  PMID:  15010610
• The fast and transient transcriptional network of gravity and mechanical stimulation in the Arabidopsis root apex.   DOI:  10.1104/pp.104.044594 ;  PMID:  15347791
• Arabidopsis PIAL1 and 2 promote SUMO chain formation as E4-type SUMO ligases and are involved in stress responses and sulfur metabolism.   DOI:  10.1105/tpc.114.131300 ;  PMID:  25415977
• CORRECTION.   DOI:  10.1105/tpc.16.00306 ;  PMID:  27129483
• Protein sumoylation and phosphorylation intersect in Arabidopsis signaling.   DOI:  10.1111/tpj.13575 ;  PMID:  28419593
• Expression and Purification of the Arabidopsis E4 SUMO Ligases PIAL1 and PIAL2.   DOI:  10.21769/BioProtoc.1544 ;  PMID:  29085855
• Functional analysis of an Arabidopsis thaliana abiotic stress-inducible facilitated diffusion transporter for monosaccharides.   DOI:  10.1074/jbc.M109.054288 ;  PMID:  19901034
• ERD6, a cDNA clone for an early dehydration-induced gene of Arabidopsis, encodes a putative sugar transporter.   DOI:  10.1016/s0005-2736(98)00007-8 ;  PMID:  9545564
• Arabidopsis POLYOL TRANSPORTER5, a new member of the monosaccharide transporter-like superfamily, mediates H+-Symport of numerous substrates, including myo-inositol, glycerol, and ribose.   DOI:  10.1105/tpc.104.026641 ;  PMID:  15598803
• and ABA-regulated transcription networks in Arabidopsis by microarray analysis and promoter classification using a Relevance Vector Machine.   DOI:  10.1101/gr.4237406 ;  PMID:  16424108
• How to decide? Different methods of calculating gene expression from short oligonucleotide array data will give different results.   DOI:  10.1186/1471-2105-7-137 ;  PMID:  16539732
• Arabidopsis INOSITOL TRANSPORTER4 mediates high-affinity H+ symport of myoinositol across the plasma membrane.   DOI:  10.1104/pp.106.077123 ;  PMID:  16603666
• Characterization and functional investigation of an Arabidopsis cDNA encoding a homologue to the d-PGMase superfamily.   DOI:  10.1093/jxb/eri105 ;  PMID:  15737980
• Identification of three distinct phylogenetic groups of CAX cation/proton antiporters.   DOI:  10.1007/s00239-006-0048-4 ;  PMID:  17086450
• Characterization of an AtCCX5 gene from Arabidopsis thaliana that involves in high-affinity K⁺ uptake and Na⁺ transport in yeast.   DOI:  10.1016/j.bbrc.2011.09.030 ;  PMID:  21945443
• Tissue-specific root ion profiling reveals essential roles of the CAX and ACA calcium transport systems in response to hypoxia in Arabidopsis.   DOI:  10.1093/jxb/erw034 ;  PMID:  26889007
• Genome-wide analysis of NBS-LRR-encoding genes in Arabidopsis.   DOI:  10.1105/tpc.009308 ;  PMID:  12671079
• A genomic analysis of the shade avoidance response in Arabidopsis.   DOI:  10.1104/pp.103.034397 ;  PMID:  14645734
• The CCAAT binding factor can mediate interactions between CONSTANS-like proteins and DNA.   DOI:  10.1111/j.1365-313X.2006.02706.x ;  PMID:  16623906
• CONSTANS and the CCAAT box binding complex share a functionally important domain and interact to regulate flowering of Arabidopsis.   DOI:  10.1105/tpc.106.043299 ;  PMID:  17138697
• Patterns of gene duplication in the plant SKP1 gene family in angiosperms: evidence for multiple mechanisms of rapid gene birth.   DOI:  10.1111/j.1365-313X.2007.03097.x ;  PMID:  17470057
• NF-YC3, NF-YC4 and NF-YC9 are required for CONSTANS-mediated, photoperiod-dependent flowering in Arabidopsis thaliana.   DOI:  10.1111/j.1365-313X.2010.04247.x ;  PMID:  20487380
• Functional conservation of rice OsNF-YB/YC and Arabidopsis AtNF-YB/YC proteins in the regulation of flowering time.   DOI:  10.1007/s00299-015-1927-1 ;  PMID:  26754793
• The NF-YC-RGL2 module integrates GA and ABA signalling to regulate seed germination in Arabidopsis.   DOI:  10.1038/ncomms12768 ;  PMID:  27624486
• NUCLEAR FACTOR Y, Subunit C (NF-YC) Transcription Factors Are Positive Regulators of Photomorphogenesis in Arabidopsis thaliana.   DOI:  10.1371/journal.pgen.1006333 ;  PMID:  27685091
• Arabidopsis NF-YCs Mediate the Light-Controlled Hypocotyl Elongation via Modulating Histone Acetylation.   DOI:  10.1016/j.molp.2016.11.007 ;  PMID:  27876642
• CONSTANS Imparts DNA Sequence Specificity to the Histone Fold NF-YB/NF-YC Dimer.   DOI:  10.1105/tpc.16.00864 ;  PMID:  28526714
• Overexpression of the transcription factor NF-YC9 confers abscisic acid hypersensitivity in Arabidopsis.   DOI:  10.1007/s11103-017-0661-1 ;  PMID:  28924726
• Arabidopsis ABF3 and ABF4 Transcription Factors Act with the NF-YC Complex to Regulate SOC1 Expression and Mediate Drought-Accelerated Flowering.   DOI:  10.1016/j.molp.2019.01.002 ;  PMID:  30639313
• TCP7 interacts with Nuclear Factor-Ys to promote flowering by directly regulating SOC1 in Arabidopsis.   DOI:  10.1111/tpj.15524 ;  PMID:  34607390
• PRMT6 physically associates with nuclear factor Y to regulate photoperiodic flowering in Arabidopsis.   DOI:  10.1007/s42994-021-00065-y ;  PMID:  36304422
• A plant outer mitochondrial membrane protein with high amino acid sequence identity to a chloroplast protein import receptor.   DOI:  10.1016/s0014-5793(03)01457-1 ;  PMID:  14741350
• Subcellular localization and tissue specific expression of amidase 1 from Arabidopsis thaliana.   DOI:  10.1007/s00425-006-0304-2 ;  PMID:  16738862
• Arabidopsis amidase 1, a member of the amidase signature family.   DOI:  10.1111/j.1742-4658.2007.05876.x ;  PMID:  17555521
• Toc64/OEP64 is not essential for the efficient import of proteins into chloroplasts in Arabidopsis thaliana.   DOI:  10.1111/j.1365-313X.2007.03207.x ;  PMID:  17655652
• The AMI1 gene family: indole-3-acetamide hydrolase functions in auxin biosynthesis in plants.   DOI:  10.1093/jxb/erp292 ;  PMID:  19887500
• Indole-3-acetamide-dependent auxin biosynthesis: a widely distributed way of indole-3-acetic acid production?   DOI:  10.1016/j.ejcb.2010.06.021 ;  PMID:  20701997
• Expression of AMIDASE1 (AMI1) is suppressed during the first two days after germination.   DOI:  10.4161/psb.5.12.13810 ;  PMID:  21150258
• Function of type-2 Arabidopsis hemoglobin in the auxin-mediated formation of embryogenic cells during morphogenesis.   DOI:  10.1111/tpj.12181 ;  PMID:  23510449
• Characterization of Four Bifunctional Plant IAM/PAM-Amidohydrolases Capable of Contributing to Auxin Biosynthesis.   DOI:  10.3390/plants3030324 ;  PMID:  27135507
• Cellular localization of the Arabidopsis class 2 phytoglobin influences somatic embryogenesis.   DOI:  10.1093/jxb/erx003 ;  PMID:  28199692
• Structural components involved in plastid protein import.   DOI:  10.1042/EBC20170093 ;  PMID:  29487196
• Function of histone H2B monoubiquitination in transcriptional regulation of auxin biosynthesis in Arabidopsis.   DOI:  10.1038/s42003-021-01733-x ;  PMID:  33589721
• Beyond the Usual Suspects: Physiological Roles of the Arabidopsis Amidase Signature (AS) Superfamily Members in Plant Growth Processes and Stress Responses.   DOI:  10.3390/biom11081207 ;  PMID:  34439873
• The Indole-3-Acetamide-Induced Arabidopsis Transcription Factor MYB74 Decreases Plant Growth and Contributes to the Control of Osmotic Stress Responses.   DOI:  10.3389/fpls.2022.928386 ;  PMID:  35812959
• Arabidopsis GUX proteins are glucuronyltransferases responsible for the addition of glucuronic acid side chains onto xylan.   DOI:  10.1093/pcp/pcs064 ;  PMID:  22537759
• Three members of the Arabidopsis glycosyltransferase family 8 are xylan glucuronosyltransferases.   DOI:  10.1104/pp.112.200964 ;  PMID:  22706449
• GUX1 and GUX2 glucuronyltransferases decorate distinct domains of glucuronoxylan with different substitution patterns.   DOI:  10.1111/tpj.12135 ;  PMID:  23373848
• Functional analysis of oxidative stress-activated mitogen-activated protein kinase cascade in plants.   DOI:  10.1073/pnas.97.6.2940 ;  PMID:  10717008

Sequences: