Gene Details:
- Gene ID: AT1G04250
- Gene Symbol: AtIAA17, AXR3, IAA17
- Gene Name: AUXIN RESISTANT 3, indole-3-acetic acid inducible 17
- Description: AUX/IAA transcriptional regulator family protein;(source:Araport11)
- TAIR Accession: locus:2018374
- Genome: Araport11_genome_release
- Species: Arabidopsis thaliana
Transcripts:
Plant Ontology Annotations:
- PO:0000013 — cauline leaf — hoja caulinar (Spanish, exact), 茎生葉、茎葉 (Japanese, exact)
- PO:0000230 — inflorescence meristem — meristema de la inflorescencia (Spanish, exact), 花序分裂組織 (Japanese, exact)
- PO:0009010 — seed — semilla (Spanish, exact), 種子 (Japanese, exact), pyrene (narrow), diaspore (broad)
- PO:0009030 — carpel — carpelo (Spanish, exact), 心皮 (Japanese, exact), Poaceae carpel (narrow), Zea carpel (narrow), pistil (broad)
- PO:0009032 — petal — pétalo (Spanish, exact), 花弁 (Japanese, exact)
- PO:0009047 — stem — caña (Spanish, exact), culm (exact), eje primario (Spanish, exact), primary axis (exact), primary stem (exact), tallo (Spanish, exact), tronco (Spanish, exact), 茎 (Japanese, exact), bole (narrow), cane (narrow), caudex (narrow), caudices (narrow), core (narrow), primocane (narrow), scape (narrow), stalk (narrow), trunk (narrow)
- PO:0025281 — pollen — polen (Spanish, exact), pollen grain (exact), 花粉 (Japanese, exact)
- PO:0000084 — plant sperm cell — célula espermática o esperma (Spanish, exact), male gamete (exact), microgamete (exact), 植物精子細胞 (Japanese, exact), sperm nucleus (related), sperm cell (broad)
- PO:0000293 — guard cell — célula guardiana (Spanish, exact), occlusive cell (exact), 孔辺細胞 (Japanese, exact)
Gene Ontology:
- GO:0003700 — enables — DNA-binding transcription factor activity
- GO:0009734 — acts upstream of or within — auxin-activated signaling pathway
- GO:0005634 — located in — nucleus
- GO:0005515 — enables — protein binding
- GO:0006355 — involved in — regulation of DNA-templated transcription
- GO:1900057 — acts upstream of or within — positive regulation of leaf senescence
Germplasm Phenotype:
- CS25215 — No visible phenotype.
- CS25216 — No visible phenotype.
- CS57504 — Increased amplitude of auxin responses, increased apical dominance, leaf rolling, reduced leaf expansion, short hypocotyl in darkness, agravitropic hypocotyl and roots, increased adventitious rooting, reduced root growth and no root hairs.
- CS57505 — Increased amplitude of auxin responses, increased apical dominance, leaf rolling, reduced leaf expansion, short hypocotyl in darkness, agravitropic hypocotyl and roots, increased adventitious rooting, reduced root growth and no root hairs.
- CS57505 — Less sensitive to brassinolide than wildtype, in terms of dark-grown hypocotyl elongation.
- CS57505 — The mutant is less affected by brassinolide than wildtype with regard to inhibition of root elongation.
- CS9569 — mild root growth phenotypes; root length slightly shorter than wild type; roots grow downward in response to gravity, but are abnormally straight
- axr3 mutant — auxin resistant, small uprolled leaf, agrotropic root
- axr3-1R4 revertant — Reversion of axr3-1 phenotype to WT-like
Function-related keywords:
- cauline leaf , inflorescence meristem , seed , carpel , petal , stem , pollen , plant sperm cell , guard cell
Literature:
- Biosynthesis of the vitamin E compound delta-tocotrienol in recombinant Escherichia coli cells. DOI: 10.1002/cbic.200800242 ; PMID: 18810749
- Nuclear targeted AtS40 modulates senescence associated gene expression in Arabidopsis thaliana during natural development and in darkness. DOI: 10.1007/s11103-010-9618-3 ; PMID: 20238146
- 4-hydroxyphenylpyruvate dioxygenase catalysis: identification of catalytic residues and production of a hydroxylated intermediate shared with a structurally unrelated enzyme. DOI: 10.1074/jbc.M111.227595 ; PMID: 21613226
- Transgenic rice grains expressing a heterologous ρ-hydroxyphenylpyruvate dioxygenase shift tocopherol synthesis from the γ to the α isoform without increasing absolute tocopherol levels. DOI: 10.1007/s11248-012-9601-7 ; PMID: 22361804
- Genetic and biochemical basis for alternative routes of tocotrienol biosynthesis for enhanced vitamin E antioxidant production. DOI: 10.1111/tpj.12067 ; PMID: 23137278
- Synthesis and Herbicidal Activity of Triketone-Quinoline Hybrids as Novel 4-Hydroxyphenylpyruvate Dioxygenase Inhibitors. DOI: 10.1021/acs.jafc.5b01530 ; PMID: 26006257
- Discovery of (2-benzoylethen-1-ol)-containing 1,2-benzothiazine derivatives as novel 4-hydroxyphenylpyruvate dioxygenase (HPPD) inhibiting-based herbicide lead compounds. DOI: 10.1016/j.bmc.2015.11.032 ; PMID: 26682702
- A novel amperometric biosensor for ß-triketone herbicides based on hydroxyphenylpyruvate dioxygenase inhibition: A case study for sulcotrione. DOI: 10.1016/j.talanta.2015.09.030 ; PMID: 26695298
- Biochemical properties and subcellular localization of tyrosine aminotransferases in Arabidopsis thaliana. DOI: 10.1016/j.phytochem.2016.09.007 ; PMID: 27726859
- An Efficient One-Pot Synthesis of 2-(Aryloxyacetyl)cyclohexane-1,3-diones as Herbicidal 4-Hydroxyphenylpyruvate Dioxygenase Inhibitors. DOI: 10.1021/acs.jafc.6b04110 ; PMID: 27933872
- Recent Advances in our Understanding of Tocopherol Biosynthesis in Plants: An Overview of Key Genes, Functions, and Breeding of Vitamin E Improved Crops. DOI: 10.3390/antiox6040099 ; PMID: 29194404
- Transcriptome responses to the natural phytotoxin t-chalcone in Arabidopsis thaliana L. DOI: 10.1002/ps.5405 ; PMID: 30868714
- Free energy calculations elucidate substrate binding, gating mechanism, and tolerance-promoting mutations in herbicide target 4-hydroxyphenylpyruvate dioxygenase. DOI: 10.1002/pro.3612 ; PMID: 30945368
- A Role for Tocopherol Biosynthesis in Arabidopsis Basal Immunity to Bacterial Infection. DOI: 10.1104/pp.19.00618 ; PMID: 31515446
- Pyrazole-Isoindoline-1,3-dione Hybrid: A Promising Scaffold for 4-Hydroxyphenylpyruvate Dioxygenase Inhibitors. DOI: 10.1021/acs.jafc.9b04917 ; PMID: 31525997
- Discovery of N-Aroyl Diketone/Triketone Derivatives as Novel 4-Hydroxyphenylpyruvate Dioxygenase Inhibiting-Based Herbicides. DOI: 10.1021/acs.jafc.9b01412 ; PMID: 31589436
- Isolation and Characterization of a Topramezone-Resistant 4-Hydroxyphenylpyruvate Dioxygenase from Sphingobium sp. TPM-19. DOI: 10.1021/acs.jafc.9b06871 ; PMID: 31884791
- Aclonifen targets solanesyl diphosphate synthase, representing a novel mode of action for herbicides. DOI: 10.1002/ps.5781 ; PMID: 32034864
- Discovery of novel arylthioacetic acid derivatives as 4-hydroxyphenylpyruvate dioxygenase inhibitors. DOI: 10.1002/ps.5967 ; PMID: 32578327
- Discovery of novel benzofuran scaffold as 4-hydroxyphenylpyruvate dioxygenase inhibitors. DOI: 10.1002/ps.6159 ; PMID: 33128494
- Structure-Guided Discovery of Silicon-Containing Subnanomolar Inhibitor of Hydroxyphenylpyruvate Dioxygenase as a Potential Herbicide. DOI: 10.1021/acs.jafc.0c03844 ; PMID: 33395281
- Induction of tocopherol biosynthesis through heat shock treatment in Arabidopsis. DOI: 10.1093/bbb/zbaa053 ; PMID: 33624783
- Synthesis and Herbicidal Activity of Triketone-Aminopyridines as Potent p-Hydroxyphenylpyruvate Dioxygenase Inhibitors. DOI: 10.1021/acs.jafc.0c07782 ; PMID: 33999624
- Unravelling Phytotoxicity and Mode of Action of Tripyrasulfone, a Novel Herbicide. DOI: 10.1021/acs.jafc.1c01294 ; PMID: 34152147
- Rational Redesign of Enzyme via the Combination of Quantum Mechanics/Molecular Mechanics, Molecular Dynamics, and Structural Biology Study. DOI: 10.1021/jacs.1c06227 ; PMID: 34542283
- Novel Pyrazole Amides as Potential 4-Hydroxyphenylpyruvate Dioxygenase Inhibitors. DOI: 10.1021/acs.jafc.2c02123 ; PMID: 35687877
- Discovery of Novel Pyrazole Derivatives with Improved Crop Safety as 4-Hydroxyphenylpyruvate Dioxygenase-Targeted Herbicides. DOI: 10.1021/acs.jafc.2c07551 ; PMID: 36848139
- Discovery of novel HPPD inhibitors: Virtual screening, molecular design, structure modification and biological evaluation. DOI: 10.1016/j.pestbp.2023.105390 ; PMID: 37105629
- Determination of the Association between Mesotrione Sensitivity and Conformational Change of 4-Hydroxyphenylpyruvate Dioxygenase via Free-Energy Analyses. DOI: 10.1021/acs.jafc.3c01253 ; PMID: 37277962
- The action of ARGONAUTE1 in the miRNA pathway and its regulation by the miRNA pathway are crucial for plant development. DOI: 10.1101/gad.1201404 ; PMID: 15131082
- Novel and stress-regulated microRNAs and other small RNAs from Arabidopsis. DOI: 10.1105/tpc.104.022830 ; PMID: 15258262
- Genome-wide analysis of the RNA-DEPENDENT RNA POLYMERASE6/DICER-LIKE4 pathway in and tasiRNA-directed targeting. DOI: 10.1105/tpc.107.050062 ; PMID: 17400893
- MicroRNA400-guided cleavage of Pentatricopeptide repeat protein mRNAs Renders Arabidopsis thaliana more susceptible to pathogenic bacteria and fungi. DOI: 10.1093/pcp/pcu096 ; PMID: 25008976
- First glance at the plant APC/C, a highly conserved ubiquitin-protein ligase. DOI: 10.1016/S1360-1385(02)00028-6 ; PMID: 12597875
- Concerted expression of a cell cycle regulator and a metabolic enzyme from a bicistronic transcript in plants. DOI: 10.1038/s41477-019-0358-3 ; PMID: 30737513
- MIW1 participates in ABA signaling through the regulation of MYB30 in Arabidopsis. DOI: 10.1016/j.plantsci.2023.111717 ; PMID: 37105379
- Cross-talk between ethylene and drought signalling pathways is mediated by the sunflower Hahb-4 transcription factor. DOI: 10.1111/j.1365-313X.2006.02865.x ; PMID: 16972869
- Transcriptional profile of the Arabidopsis root quiescent center. DOI: 10.1105/tpc.105.031724 ; PMID: 15937229
- Regulon organization of Arabidopsis. DOI: 10.1186/1471-2229-8-99 ; PMID: 18826618
- The Arabidopsis mutant jason produces unreduced first division restitution male gametes through a parallel/fused spindle mechanism in meiosis II. DOI: 10.1104/pp.110.170415 ; PMID: 21257792
- An imprinted gene underlies postzygotic reproductive isolation in Arabidopsis thaliana. DOI: 10.1016/j.devcel.2013.08.006 ; PMID: 24012484
- The Chromatin Protein DUET/MMD1 Controls Expression of the Meiotic Gene TDM1 during Male Meiosis in Arabidopsis. DOI: 10.1371/journal.pgen.1005396 ; PMID: 26348709
- Organelles maintain spindle position in plant meiosis. DOI: 10.1038/ncomms7492 ; PMID: 25757555
- The meiotic regulator JASON utilizes alternative translation initiation sites to produce differentially localized forms. DOI: 10.1093/jxb/erx222 ; PMID: 28922756
- An Arabidopsis cDNA encoding a DNA-binding protein that is highly similar to the DEAH family of RNA/DNA helicase genes. DOI: 10.1093/nar/27.18.3728 ; PMID: 10471743
- Expression of biologically recombinant human acidic fibroblast growth factor in Arabidopsis thaliana seeds via oleosin fusion technology. DOI: 10.1016/j.gene.2015.04.036 ; PMID: 25889272
- Chloroplast SecY is complexed to SecE and involved in the translocation of the 33-kDa but not the 23-kDa subunit of the oxygen-evolving complex. DOI: 10.1074/jbc.274.17.12177 ; PMID: 10207046
- Nucleotide sequence of the psbP gene encoding precursor of 23-kDa polypeptide of oxygen-evolving complex in Arabidopsis thaliana and its expression in the wild-type and a constitutively photomorphogenic mutant. DOI: 10.1093/dnares/3.5.277 ; PMID: 9039496
- dependent protein transporter in thylakoid membrane formation during chloroplast development in Arabidopsis thaliana. DOI: 10.1073/pnas.181304598 ; PMID: 11526245
- Oxygen-evolving enhancer protein 2 is phosphorylated by glycine-rich protein 3/wall-associated kinase 1 in Arabidopsis. DOI: 10.1016/s0006-291x(03)00851-9 ; PMID: 12767910
- PsbR, a missing link in the assembly of the oxygen-evolving complex of plant photosystem II. DOI: 10.1074/jbc.M510600200 ; PMID: 16282331
- The nuclear-encoded factor HCF173 is involved in the initiation of translation of the psbA mRNA in Arabidopsis thaliana. DOI: 10.1105/tpc.106.042895 ; PMID: 17435084
- Identification of proteins expressed at extremely low level in Arabidopsis leaves. DOI: 10.1016/j.bbrc.2007.04.189 ; PMID: 17511964
- The effects of simultaneous RNAi suppression of PsbO and PsbP protein expression in photosystem II of Arabidopsis. DOI: 10.1007/s11120-008-9352-8 ; PMID: 18791808
- The PsbP protein, but not the PsbQ protein, is required for normal thylakoid architecture in Arabidopsis thaliana. DOI: 10.1016/j.febslet.2009.05.048 ; PMID: 19500580
- The significance of protein maturation by plastidic type I signal peptidase 1 for thylakoid development in Arabidopsis chloroplasts. DOI: 10.1104/pp.109.151977 ; PMID: 20097790
- A dual-targeted purple acid phosphatase in Arabidopsis thaliana moderates carbon metabolism and its overexpression leads to faster plant growth and higher seed yield. DOI: 10.1111/j.1469-8137.2011.04026.x ; PMID: 22269069
- Cross-talk between calcium signalling and protein phosphorylation at the thylakoid. DOI: 10.1093/jxb/err403 ; PMID: 22197893
- Proteomic signatures implicate cAMP in light and temperature responses in Arabidopsis thaliana. DOI: 10.1016/j.jprot.2013.02.032 ; PMID: 23517717
- Arabidopsis plants lacking PsbQ and PsbR subunits of the oxygen-evolving complex show altered PSII super-complex organization and short-term adaptive mechanisms. DOI: 10.1111/tpj.12230 ; PMID: 23647309
- Analysis of the chloroplast proteome in arc mutants and identification of novel protein components associated with FtsZ2. DOI: 10.1007/s11103-012-9994-y ; PMID: 23225155
- Multiple fates of non-mature lumenal proteins in thylakoids. DOI: 10.1111/tpj.12273 ; PMID: 23802992
- Expression of the nuclear gene encoding oxygen-evolving enhancer protein 2 is required for high levels of photosynthetic oxygen evolution in Chlamydomonas reinhardtii. DOI: 10.1073/pnas.84.3.749 ; PMID: 3468511
- PsbP protein, but not PsbQ protein, is essential for the regulation and stabilization of photosystem II in higher plants. DOI: 10.1104/pp.105.068643 ; PMID: 16244145
- Arabidopsis Tic40 expression in tobacco chloroplasts results in massive proliferation of the inner envelope membrane and upregulation of associated proteins. DOI: 10.1105/tpc.108.063172 ; PMID: 19060109
- Tocopherol cyclase (VTE1) localization and vitamin E accumulation in chloroplast plastoglobule lipoprotein particles. DOI: 10.1074/jbc.M511939200 ; PMID: 16414959
- Protein profiling of plastoglobules in chloroplasts and chromoplasts. A surprising site for differential accumulation of metabolic enzymes. DOI: 10.1104/pp.105.076083 ; PMID: 16461379
- The Arabidopsis protein kinase PTI1-2 is activated by convergent phosphatidic acid and oxidative stress signaling pathways downstream of PDK1 and OXI1. DOI: 10.1074/jbc.M607341200 ; PMID: 17040918
- The Arabidopsis protein kinase Pto-interacting 1-4 is a common target of the oxidative signal-inducible 1 and mitogen-activated protein kinases. DOI: 10.1111/j.1742-4658.2011.08033.x ; PMID: 21276203
- Monomerization of abscisic acid receptors through CARKs-mediated phosphorylation. DOI: 10.1111/nph.18149 ; PMID: 35388459
- The pentatricopeptide repeat MTSF1 protein stabilizes the nad4 mRNA in Arabidopsis mitochondria. DOI: 10.1093/nar/gkt337 ; PMID: 23658225
- The pentatricopeptide repeat protein MTSF2 stabilizes a nad1 precursor transcript and defines the 3΄ end of its 5΄-half intron. DOI: 10.1093/nar/gkx162 ; PMID: 28334831
Sequences:
cDNA Sequence
- >AT1G04250.1
AGATAAATCATAAGAAAGATTCAATAACAGTAATAGAGTAATAACAGTGATTACTGATTAGTCTAAAAGACTAAAACTCGAGGATGATGACTTAATCAAAGGGCTTAGATTCATCCACGTGTCTAAAACCCGTTTAATCAAAGATCTCTTAAATACGACATACACATGCAGCTACCTCCTAGACAGAGATATAATACAGACTCATCTCACTTTGTATTATTTGAGTGTTTTTATAAAACCATTTTTCCATCTTCCTCATCACCTTCCCAAGAAGAAGAACACCAAAGAAGAAGAAAGGTTAATAATGATGGGCAGTGTCGAGCTGAATCTGAGGGAGACTGAGCTGTGTCTTGGTCTTCCCGGTGGAGATACAGTGGCTCCGGTAACCGGAAACAAGAGAGGGTTCTCAGAGACGGTTGATCTGAAGCTAAATCTGAATAATGAGCCTGCAAACAAGGAAGGATCTACGACTCATGACGTCGTGACTTTTGATTCCAAGGAGAAGAGTGCTTGTCCTAAAGATCCAGCCAAACCTCCGGCCAAGGCACAAGTTGTGGGATGGCCACCGGTGAGATCATACCGGAAGAACGTGATGGTTTCCTGCCAAAAATCAAGCGGTGGCCCGGAGGCGGCGGCGTTCGTGAAGGTATCAATGGACGGAGCACCGTACTTGAGGAAAATCGATTTGAGGATGTATAAAAGCTACGATGAGCTTTCTAATGCTTTGTCCAACATGTTCAGCTCTTTTACCATGGGCAAACATGGAGGAGAAGAAGGAATGATAGACTTCATGAATGAGAGGAAATTGATGGATTTGGTGAATAGCTGGGACTATGTTCCCTCTTATGAAGACAAAGACGGTGATTGGATGCTCGTCGGCGACGTTCCTTGGCCAATGTTCGTCGATACATGCAAGCGTTTACGTCTCATGAAAGGATCGGATGCCATTGGTCTCGCTCCGAGGGCGATGGAGAAGTGCAAGAGCAGAGCTTGAAGTCAAATTAAAAGGATAAGTGGTATCGATTATATATTTGATTAACACATTGATTGGTGTTAATTGCTCTTTTTTTTCTTACGATGAAATACATTGTTCAGTTTCTTTTGATTGTCTGTGTTTTGATCTGGATTTGGTATGTAGATATAGTTTGTATGCTATTATGTGTAATGAACTTAAGTTAAATATTTGAGACATTTGTAATGGAAAATGTGTAATAATTTGAACATCCTATTCCTATGTATATGTTTGTCTTTATTTATTTATTTTGCCAAAGATGTGTATATTCGTATAAGGAATATGTGATTTTTATTCCACTATGG
CDS Sequence
- >AT1G04250.1
ATGATGGGCAGTGTCGAGCTGAATCTGAGGGAGACTGAGCTGTGTCTTGGTCTTCCCGGTGGAGATACAGTGGCTCCGGTAACCGGAAACAAGAGAGGGTTCTCAGAGACGGTTGATCTGAAGCTAAATCTGAATAATGAGCCTGCAAACAAGGAAGGATCTACGACTCATGACGTCGTGACTTTTGATTCCAAGGAGAAGAGTGCTTGTCCTAAAGATCCAGCCAAACCTCCGGCCAAGGCACAAGTTGTGGGATGGCCACCGGTGAGATCATACCGGAAGAACGTGATGGTTTCCTGCCAAAAATCAAGCGGTGGCCCGGAGGCGGCGGCGTTCGTGAAGGTATCAATGGACGGAGCACCGTACTTGAGGAAAATCGATTTGAGGATGTATAAAAGCTACGATGAGCTTTCTAATGCTTTGTCCAACATGTTCAGCTCTTTTACCATGGGCAAACATGGAGGAGAAGAAGGAATGATAGACTTCATGAATGAGAGGAAATTGATGGATTTGGTGAATAGCTGGGACTATGTTCCCTCTTATGAAGACAAAGACGGTGATTGGATGCTCGTCGGCGACGTTCCTTGGCCAATGTTCGTCGATACATGCAAGCGTTTACGTCTCATGAAAGGATCGGATGCCATTGGTCTCGCTCCGAGGGCGATGGAGAAGTGCAAGAGCAGAGCTTGA
Protein Sequence
- >AT1G04250.1
MMGSVELNLRETELCLGLPGGDTVAPVTGNKRGFSETVDLKLNLNNEPANKEGSTTHDVVTFDSKEKSACPKDPAKPPAKAQVVGWPPVRSYRKNVMVSCQKSSGGPEAAAFVKVSMDGAPYLRKIDLRMYKSYDELSNALSNMFSSFTMGKHGGEEGMIDFMNERKLMDLVNSWDYVPSYEDKDGDWMLVGDVPWPMFVDTCKRLRLMKGSDAIGLAPRAMEKCKSRA