Information report for AT1G04240
Gene Details
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Functional Descriptions
- PO:0000013 — cauline leaf — hoja caulinar (Spanish, exact), 茎生葉、茎葉 (Japanese, exact)
- PO:0000230 — inflorescence meristem — meristema de la inflorescencia (Spanish, exact), 花序分裂組織 (Japanese, exact)
- PO:0009010 — seed — semilla (Spanish, exact), 種子 (Japanese, exact), pyrene (narrow), diaspore (broad)
- PO:0009030 — carpel — carpelo (Spanish, exact), 心皮 (Japanese, exact), Poaceae carpel (narrow), Zea carpel (narrow), pistil (broad)
- PO:0009032 — petal — pétalo (Spanish, exact), 花弁 (Japanese, exact)
- PO:0009047 — stem — caña (Spanish, exact), culm (exact), eje primario (Spanish, exact), primary axis (exact), primary stem (exact), tallo (Spanish, exact), tronco (Spanish, exact), 茎 (Japanese, exact), bole (narrow), cane (narrow), caudex (narrow), caudices (narrow), core (narrow), primocane (narrow), scape (narrow), stalk (narrow), trunk (narrow)
- PO:0025281 — pollen — polen (Spanish, exact), pollen grain (exact), 花粉 (Japanese, exact)
- PO:0025034 — leaf — hoja (Spanish, exact), 葉 (Japanese, exact)
- PO:0000293 — guard cell — célula guardiana (Spanish, exact), occlusive cell (exact), 孔辺細胞 (Japanese, exact)
- GO:0005515 — enables — protein binding
- GO:0006355 — involved in — regulation of DNA-templated transcription
- GO:0009733 — acts upstream of or within — response to auxin
- GO:0005634 — located in — nucleus
- GO:0000976 — enables — transcription cis-regulatory region binding
- GO:0003700 — enables — DNA-binding transcription factor activity
- GO:0042802 — enables — identical protein binding
Functional Keywords
- cauline leaf , inflorescence meristem , seed , carpel , petal , stem , pollen , leaf , guard cell
Literature and News
- Brassinosteroids regulate pavement cell growth by mediating BIN2-induced microtubule stabilization. DOI: 10.1093/jxb/erx467 ; PMID: 29329424
- Comparative Analysis of CDPK Family in Maize, Arabidopsis, Rice, and Sorghum Revealed Potential Targets for Drought Tolerance Improvement. DOI: 10.3389/fchem.2017.00115 ; PMID: 29312925
- GSK3-like kinase BIN2 phosphorylates RD26 to potentiate drought signaling in Arabidopsis. DOI: 10.1111/tpj.14484 ; PMID: 31357236
- The GSK3-like Kinase BIN2 Is a Molecular Switch between the Salt Stress Response and Growth Recovery in Arabidopsis thaliana. DOI: 10.1016/j.devcel.2020.08.005 ; PMID: 32891194
- NA DOI: NA ; PMID: 33831152
- Arabidopsis NF-YCs play dual roles in repressing brassinosteroid biosynthesis and signaling during light-regulated hypocotyl elongation. DOI: 10.1093/plcell/koab112 ; PMID: 33871651
- GSK3s: nodes of multilayer regulation of plant development and stress responses. DOI: 10.1016/j.tplants.2021.07.017 ; PMID: 34417080
- Heat Shock-Induced Accumulation of the Glycogen Synthase Kinase 3-Like Kinase BRASSINOSTEROID INSENSITIVE 2 Promotes Early Flowering but Reduces Thermotolerance in Arabidopsis. DOI: 10.3389/fpls.2022.838062 ; PMID: 35154235
- Enhanced growth rate under elevated CO(2) conditions was observed for transgenic lines of genes identified by intraspecific variation analyses in Arabidopsis thaliana. DOI: 10.1007/s11103-022-01265-w ; PMID: 35397102
- Analyses of genes encoding the Glycogen Synthase Kinases in rice and Arabidopsis reveal mechanisms which regulate their expression during development and responses to abiotic stresses. DOI: 10.1016/j.plantsci.2023.111724 ; PMID: 37142096
- Altered ARA2 (RABA1a) expression in Arabidopsis reveals the involvement of a Rab/YPT family member in auxin-mediated responses. DOI: 10.1007/s11103-009-9460-7 ; PMID: 19199049
- Proportional subcellular localization of Arabidopsis thaliana RabA1a. DOI: 10.1080/15592324.2019.1581561 ; PMID: 30764708
- An unexpected plethora of trehalose biosynthesis genes in Arabidopsis thaliana. DOI: 10.1016/s1360-1385(01)02125-2 ; PMID: 11701378
- Trehalose metabolism in Arabidopsis: occurrence of trehalose and molecular cloning and characterization of trehalose-6-phosphate synthase homologues. DOI: 10.1093/jexbot/52.362.1817 ; PMID: 11520870
- Is trehalose-6-phosphate a regulator of sugar metabolism in plants? DOI: 10.1093/jxb/erg039 ; PMID: 12508064
- The transcriptional co-activator MBF1c is a key regulator of thermotolerance in Arabidopsis thaliana. DOI: 10.1074/jbc.M709187200 ; PMID: 18201973
- Extensive expression regulation and lack of heterologous enzymatic activity of the Class II trehalose metabolism proteins from Arabidopsis thaliana. DOI: 10.1111/j.1365-3040.2009.01985.x ; PMID: 19344332
- Coordinated regulation and complex formation of yellow variegated1 and yellow variegated2, chloroplastic FtsH metalloproteases involved in the repair cycle of photosystem II in Arabidopsis thylakoid membranes. DOI: 10.1105/tpc.017319 ; PMID: 14630971
- A transcriptomic and proteomic characterization of the Arabidopsis mitochondrial protein import apparatus and its response to mitochondrial dysfunction. DOI: 10.1104/pp.103.033910 ; PMID: 14730085
- The Arabidopsis FtsH metalloprotease gene family: interchangeability of subunits in chloroplast oligomeric complexes. DOI: 10.1111/j.1365-313x.2003.02014.x ; PMID: 14996218
- Comparative genomics in salt tolerance between Arabidopsis and aRabidopsis-related halophyte salt cress using Arabidopsis microarray. DOI: 10.1104/pp.104.039909 ; PMID: 15247402
- Two types of FtsH protease subunits are required for chloroplast biogenesis and Photosystem II repair in Arabidopsis. DOI: 10.1105/tpc.105.035071 ; PMID: 16126834
- AtFtsH6 is involved in the degradation of the light-harvesting complex II during high-light acclimation and senescence. DOI: 10.1073/pnas.0503472102 ; PMID: 16157880
- Transcriptional profiling implicates novel interactions between abiotic stress and hormonal responses in Thellungiella, a close relative of Arabidopsis. DOI: 10.1104/pp.105.070508 ; PMID: 16500996
- Light has a specific role in modulating Arabidopsis gene expression at low temperature. DOI: 10.1186/1471-2229-8-13 ; PMID: 18230142
- Activation of the heterotrimeric G protein alpha-subunit GPA1 suppresses the ftsh-mediated inhibition of chloroplast development in Arabidopsis. DOI: 10.1111/j.1365-313X.2009.03843.x ; PMID: 19228339
- The FtsH protease heterocomplex in Arabidopsis: dispensability of type-B protease activity for proper chloroplast development. DOI: 10.1105/tpc.110.079202 ; PMID: 21062893
- FtsH2 and FtsH5: two homologous subunits use different integration mechanisms leading to the same thylakoid multimeric complex. DOI: 10.1111/j.1365-313X.2010.04448.x ; PMID: 21214651
- FtsH proteases located in the plant chloroplast. DOI: 10.1111/j.1399-3054.2011.01548.x ; PMID: 22121866
- A Plastid Phosphatidylglycerol Lipase Contributes to the Export of Acyl Groups from Plastids for Seed Oil Biosynthesis. DOI: 10.1105/tpc.17.00397 ; PMID: 28687655
- FtsH Protease in the Thylakoid Membrane: Physiological Functions and the Regulation of Protease Activity. DOI: 10.3389/fpls.2018.00855 ; PMID: 29973948
- The Photosystem II Repair Cycle Requires FtsH Turnover through the EngA GTPase. DOI: 10.1104/pp.18.00652 ; PMID: 30131421
- Recent advances in the study of Clp, FtsH and other proteases located in chloroplasts. DOI: 10.1016/j.pbi.2006.03.010 ; PMID: 16603408
- Arabidopsis deadenylases AtCAF1a and AtCAF1b play overlapping and distinct roles in mediating environmental stress responses. DOI: 10.1104/pp.109.149005 ; PMID: 19955262
- An alpha-crystallin gene, ACD31.2 from Arabidopsis is negatively regulated by FPF1 overexpression, floral induction, gibberellins, and long days. DOI: 10.1093/jxb/erh131 ; PMID: 15073212
- Identification and characterization of a stress-inducible and a constitutive small heat-shock protein targeted to the matrix of plant peroxisomes. DOI: 10.1104/pp.105.073841 ; PMID: 16531488
- Molecular cloning of two Arabidopsis UDP-galactose transporters by complementation of a deficient Chinese hamster ovary cell line. DOI: 10.1093/glycob/cwh159 ; PMID: 15456736
- Callose synthase GSL7 is necessary for normal phloem transport and inflorescence growth in Arabidopsis. DOI: 10.1104/pp.110.166330 ; PMID: 21098675
- CalS7 encodes a callose synthase responsible for callose deposition in the phloem. DOI: 10.1111/j.1365-313X.2010.04399.x ; PMID: 21175885
- Callose biosynthesis regulates symplastic trafficking during root development. DOI: 10.1016/j.devcel.2011.10.006 ; PMID: 22172675
- Gene co-expression network analysis identifies BEH3 as a stabilizer of secondary vascular development in Arabidopsis. DOI: 10.1093/plcell/koab151 ; PMID: 34059919
- Putative pectate lyase PLL12 and callose deposition through polar CALS7 are necessary for long-distance phloem transport in Arabidopsis. DOI: 10.1016/j.cub.2023.01.038 ; PMID: 36805125
- The TRIPLE PHD FINGERS proteins are required for SWI/SNF complex-mediated +1 nucleosome positioning and transcription start site determination in Arabidopsis. DOI: 10.1093/nar/gkac826 ; PMID: 36189880
- Comprehensive identification of SWI/SNF complex subunits underpins deep eukaryotic ancestry and reveals new plant components. DOI: 10.1038/s42003-022-03490-x ; PMID: 35668117
- Arabidopsis 56-amino acid serine palmitoyltransferase-interacting proteins stimulate sphingolipid synthesis, are essential, and affect mycotoxin sensitivity. DOI: 10.1105/tpc.113.116145 ; PMID: 24214397
- Impact of AtNHX1, a vacuolar Na+/H+ antiporter, upon gene expression during and long-term salt stress in Arabidopsis thaliana. DOI: 10.1186/1471-2229-7-18 ; PMID: 17411438
- Glycerol-3-phosphate acyltransferase 6 (GPAT6) is important for tapetum development in Arabidopsis and plays multiple roles in plant fertility. DOI: 10.1093/mp/ssr057 ; PMID: 21746699
- A Novel Complementation Assay for Quick and Specific Screen of Genes Encoding Glycerol-3-Phosphate Acyltransferases. DOI: 10.3389/fpls.2018.00353 ; PMID: 29616064
- A GPAT1 Mutation in Arabidopsis Enhances Plant Height but Impairs Seed Oil Biosynthesis. DOI: 10.3390/ijms22020785 ; PMID: 33466786
- The Arabidopsis tail-anchored protein PEROXISOMAL AND MITOCHONDRIAL DIVISION FACTOR1 is involved in the morphogenesis and proliferation of peroxisomes and mitochondria. DOI: 10.1105/tpc.111.090142 ; PMID: 22147290
- Characterization and subcellular compartmentation of recombinant 4-hydroxyphenylpyruvate dioxygenase from Arabidopsis in transgenic tobacco. DOI: 10.1104/pp.119.4.1507 ; PMID: 10198110
- Complementation of the Arabidopsis pds1 mutation with the gene encoding p-hydroxyphenylpyruvate dioxygenase. DOI: 10.1104/pp.117.4.1317 ; PMID: 9701587
- Genetic dissection of carotenoid synthesis in arabidopsis defines plastoquinone as an essential component of phytoene desaturation. DOI: 10.1105/tpc.7.12.2139 ; PMID: 8718624
- Mesotrione: a new selective herbicide for use in maize. DOI: 10.1002/1526-4998(200102)57:2<120::AID-PS254>3.0.CO;2-E ; PMID: 11455642
- Determination of gene copy number and genotype of transgenic Arabidopsis thaliana by competitive PCR. DOI: NA ; PMID: 12021299
- Progress in the dissection and manipulation of vitamin E synthesis. DOI: 10.1016/j.tplants.2005.10.007 ; PMID: 16290217
Gene Resources
- UniProt: A0A1P8AT43
- EMBL: CP002684
- AlphaFoldDB: A0A1P8AT43
- EnsemblPlants: AT1G04240.2
- Gramene: AT1G04240.2
- ExpressionAtlas: AT1G04240
- InterPro: IPR003311, IPR033389, IPR053793
- PANTHER: PTHR31734, PTHR31734:SF262
- SUPFAM: SSF54277
- PROSITE: PS51745
- Gene3D: 3.10.20.90
- SWISS-MODEL: A0A1P8AT43
Homologs
- Actinidia chinensis CEY00_Acc13467
- Beta vulgaris BVRB_5g120320
- Brassica napus BnaA05G0331100ZS, BnaC05G0350100ZS, BnaA03G0375100ZS
- Brassica oleracea Bo3g081600, Bo5g093110
- Brassica rapa Bra001900
- Glycine max Glyma.10G180100
- Gossypium hirsutum Gohir.D09G224500, Gohir.A09G222400, Gohir.D11G132700
- Malus domestica MdIAA3
- Manihot esculenta MANES_03G169700, MANES_15G036200
- Nicotiana attenuata A4A49_02602
- Oryza sativa OsIAA31
- Populus trichocarpa POPTR_008G161200v3
- Prunus persica PRUPE_1G027600
- Solanum lycopersicum Solyc09g083290.3
- Solanum tuberosum PGSC0003DMG400006093
Sequences
cDNA Sequence
- >AT1G04240.2
CGAAGATTTGATCTGGACCGTCTATCACAAGAAAGAAAGATGAAAATATTTTGTTTTTGGGTTTGGACAGATGGGAGAAAAAGAAAGTGTCCCCACAAATGTCCCCAAGAAGATGGGACACACTTTTGCCTCAAAGTTGCTGTTACTGCTACCGACAAGCTTAGCTTTTTTTCCTTTGTCCTTAATTCAGAAAACAGTTTCTTCTCTCTCTACCAGTATCTATCTTTATTCTCCTTTAACTTGTATAAAACACTCAGCTTCCTCGAAGCCTCTCATCTTCATCATCAGCAGCTTCTCTATATCTCTCCTCTCTTTCAAGGATAATAACCAAAAGCTTTTCTTTTTATCTTCTCCTGCAATTCTTGAAGAAATGGATGAGTTTGTTAACCTCAAGGAAACAGAGCTGAGGCTGGGATTACCGGGAACAGATAATGTATGTGAAGCAAAAGAGAGAGTTTCTTGCTGTAATAACAACAATAAGAGAGTACTATCAACTGATACTGAGAAGGAGATTGAATCATCATCAAGGAAAACTGAAACATCCCCTCCTCGAAAGGCTCAGATTGTTGGATGGCCACCAGTTAGATCTTACAGGAAGAACAACATTCAGAGTAAGAAGAATGAATCTGAGCATGAGGGTCAAGGAATCTATGTGAAAGTAAGTATGGATGGTGCACCATACTTGAGGAAAATAGATCTGAGTTGTTACAAAGGATACTCAGAGTTGCTTAAAGCTTTAGAAGTGATGTTCAAATTCTCTGTGGGAGAGTACTTTGAGAGAGATGGATATAAAGGTTCAGACTTTGTGCCTACTTATGAAGACAAAGATGGTGATTGGATGCTCATTGGTGATGTTCCATGGGAGATGTTCATATGTACGTGCAAGAGACTAAGGATCATGAAAGGATCAGAAGCCAAAGGTTTAGGCTGTGGTGTATGAGATATATCTTCAAGAAATCTAACAGAGACACAAAAGAACTTGAAGAAAAATAGAGTTTCTTTTGGTTCAGAGAAATCTCTGTCTGTGCTTGGGTTGTCGGGTTTCTCGGGCAAGATCTATGTTCATTGGATTGAATCCAATTCATAGCCTTTATTTACCTCATCGGTAAAATTCAAATGTAAACATGCTTAATGGTCTTAAGCATATGAAACTGGAACCTAATTACATTTTGTTTCAGAAACAGGGCAAAAGGTTGTCCTTAAATCTTTGGTTATGTGTATTACATTAATTAAAGTGTTATGAAGATTGAAGAGTTGTTTTTATATTTGTAGCAATTCTGTTTTGCGTTCTCATTGATCAAAGAGATTTTCAAGCAATACCCATTTTCTATTTTGGTTCACTAGTTCTTAGATCA - >AT1G04240.1
CGAAGATTTGATCTGGACCGTCTATCACAAGAAAGAAAGATGAAAATATTTTGTTTTTGGGTTTGGACAGATGGGAGAAAAAGAAAGTGTCCCCACAAATGTCCCCAAGAAGATGGGACACACTTTTGCCTCAAAGTTGCTGTTACTGCTACCGACAAGCTTAGCTTTTTTTCCTTTGTCCTTAATTCAGAAAACAGTTTCTTCTCTCTCTACCAGTATCTATCTTTATTCTCCTTTAACTTGTATAAAACACTCAGCTTCCTCGAAGCCTCTCATCTTCATCATCAGCAGCTTCTCTATATCTCTCCTCTCTTTCAAGGATAATAACCAAAAGCTTTTCTTTTTATCTTCTCCTGCAATTCTTGAAGAAATGGATGAGTTTGTTAACCTCAAGGAAACAGAGCTGAGGCTGGGATTACCGGGAACAGATAATGTATGTGAAGCAAAAGAGAGAGTTTCTTGCTGTAATAACAACAATAAGAGAGTACTATCAACTGATACTGAGAAGGAGATTGAATCATCATCAAGGAAAACTGAAACATCCCCTCCTCGAAAGGCTCAGATTGTTGGATGGCCACCAGTTAGATCTTACAGGAAGAACAACATTCAGAGTAAGAAGAATGAATCTGAGCATGAGGGTCAAGGAATCTATGTGAAAGTAAGTATGGATGGTGCACCATACTTGAGGAAAATAGATCTGAGTTGTTACAAAGGATACTCAGAGTTGCTTAAAGCTTTAGAAGTGATGTTCAAATTCTCTGTGGGAGAGTACTTTGAGAGAGATGGATATAAAGGTTCAGACTTTGTGCCTACTTATGAAGACAAAGATGGTGATTGGATGCTCATTGGTGATGTTCCATGGGAGATGTTCATATGTACGTGCAAGAGACTAAGGATCATGAAAGGATCAGAAGCCAAAGGTTTAGGCTGTGGTGTATGAGATATATCTTCAAGAAATCTAACAGAGACACAAAAGAACTTGAAGAAAAATAGAGTTTCTTTTGGTTCAGAGAAATCTCTGTCTGTGCTTGGGTTGTCGGGTTTCTCGGGCAAGATCTATGTTCATTGGATTGAATCCAATTCATAGCCTTTATTTACCTCATCGGTAAAATTCAAATGTAAACATGCTTAATGGTCTTAAGCATATGAAACTGGAACCTAATTACATTTTGTTTCAGAAACAGGGCAAAAGGTTGTCCTTAAATCTTTGGTTATGTGTATTACATTAATTAAAGTGTTATGAAGATTGAAGAGTTGTTTTTATATTTGTAGCAATTCTGTTTTGCGTTCTCATTGATCAAAGAGATTTTCAAGCAATACCCATTTTCTATTTTGGTTCACTAGTTCTTAGATCA
CDS Sequence
- >AT1G04240.2
ATGGGAGAAAAAGAAAGTGTCCCCACAAATGTCCCCAAGAAGATGGGACACACTTTTGCCTCAAAGTTGCTGTTACTGCTACCGACAAGCTTAGCTTTTTTTCCTTTGTCCTTAATTCAGAAAACAGTTTCTTCTCTCTCTACCAGTATCTATCTTTATTCTCCTTTAACTTGTATAAAACACTCAGCTTCCTCGAAGCCTCTCATCTTCATCATCAGCAGCTTCTCTATATCTCTCCTCTCTTTCAAGGATAATAACCAAAAGCTTTTCTTTTTATCTTCTCCTGCAATTCTTGAAGAAATGGATGAGTTTGTTAACCTCAAGGAAACAGAGCTGAGGCTGGGATTACCGGGAACAGATAATGTATGTGAAGCAAAAGAGAGAGTTTCTTGCTGTAATAACAACAATAAGAGAGTACTATCAACTGATACTGAGAAGGAGATTGAATCATCATCAAGGAAAACTGAAACATCCCCTCCTCGAAAGGCTCAGATTGTTGGATGGCCACCAGTTAGATCTTACAGGAAGAACAACATTCAGAGTAAGAAGAATGAATCTGAGCATGAGGGTCAAGGAATCTATGTGAAAGTAAGTATGGATGGTGCACCATACTTGAGGAAAATAGATCTGAGTTGTTACAAAGGATACTCAGAGTTGCTTAAAGCTTTAGAAGTGATGTTCAAATTCTCTGTGGGAGAGTACTTTGAGAGAGATGGATATAAAGGTTCAGACTTTGTGCCTACTTATGAAGACAAAGATGGTGATTGGATGCTCATTGGTGATGTTCCATGGGAGATGTTCATATGTACGTGCAAGAGACTAAGGATCATGAAAGGATCAGAAGCCAAAGGTTTAGGCTGTGGTGTATGA - >AT1G04240.1
ATGGGAGAAAAAGAAAGTGTCCCCACAAATGTCCCCAAGAAGATGGGACACACTTTTGCCTCAAAGTTGCTGTTACTGCTACCGACAAGCTTAGCTTTTTTTCCTTTGTCCTTAATTCAGAAAACAGTTTCTTCTCTCTCTACCAGTATCTATCTTTATTCTCCTTTAACTTGTATAAAACACTCAGCTTCCTCGAAGCCTCTCATCTTCATCATCAGCAGCTTCTCTATATCTCTCCTCTCTTTCAAGGATAATAACCAAAAGCTTTTCTTTTTATCTTCTCCTGCAATTCTTGAAGAAATGGATGAGTTTGTTAACCTCAAGGAAACAGAGCTGAGGCTGGGATTACCGGGAACAGATAATGTATGTGAAGCAAAAGAGAGAGTTTCTTGCTGTAATAACAACAATAAGAGAGTACTATCAACTGATACTGAGAAGGAGATTGAATCATCATCAAGGAAAACTGAAACATCCCCTCCTCGAAAGGCTCAGATTGTTGGATGGCCACCAGTTAGATCTTACAGGAAGAACAACATTCAGAGTAAGAAGAATGAATCTGAGCATGAGGGTCAAGGAATCTATGTGAAAGTAAGTATGGATGGTGCACCATACTTGAGGAAAATAGATCTGAGTTGTTACAAAGGATACTCAGAGTTGCTTAAAGCTTTAGAAGTGATGTTCAAATTCTCTGTGGGAGAGTACTTTGAGAGAGATGGATATAAAGGTTCAGACTTTGTGCCTACTTATGAAGACAAAGATGGTGATTGGATGCTCATTGGTGATGTTCCATGGGAGATGTTCATATGTACGTGCAAGAGACTAAGGATCATGAAAGGATCAGAAGCCAAAGGTTTAGGCTGTGGTGTATGA
Protein Sequence
- >AT1G04240.2
MGEKESVPTNVPKKMGHTFASKLLLLLPTSLAFFPLSLIQKTVSSLSTSIYLYSPLTCIKHSASSKPLIFIISSFSISLLSFKDNNQKLFFLSSPAILEEMDEFVNLKETELRLGLPGTDNVCEAKERVSCCNNNNKRVLSTDTEKEIESSSRKTETSPPRKAQIVGWPPVRSYRKNNIQSKKNESEHEGQGIYVKVSMDGAPYLRKIDLSCYKGYSELLKALEVMFKFSVGEYFERDGYKGSDFVPTYEDKDGDWMLIGDVPWEMFICTCKRLRIMKGSEAKGLGCGV - >AT1G04240.1
MGEKESVPTNVPKKMGHTFASKLLLLLPTSLAFFPLSLIQKTVSSLSTSIYLYSPLTCIKHSASSKPLIFIISSFSISLLSFKDNNQKLFFLSSPAILEEMDEFVNLKETELRLGLPGTDNVCEAKERVSCCNNNNKRVLSTDTEKEIESSSRKTETSPPRKAQIVGWPPVRSYRKNNIQSKKNESEHEGQGIYVKVSMDGAPYLRKIDLSCYKGYSELLKALEVMFKFSVGEYFERDGYKGSDFVPTYEDKDGDWMLIGDVPWEMFICTCKRLRIMKGSEAKGLGCGV