AT1G02580

Information report for AT1G02580

Gene Details

Gene ID: AT1G02580
Gene Symbol: EMB173, FIS1, MEA, SDG5
Gene Name: EMBRYO DEFECTIVE 173, FERTILIZATION INDEPENDENT SEED 1, MEDEA, SET DOMAIN-CONTAINING PROTEIN 5
Description: SET domain-containing protein;(source:Araport11)
TAIR Accession: locus:2196110
Genome: Araport11_genome_release
Species: Arabidopsis thaliana

Functional Descriptions

PO:0020003 — plant ovule — óvulo vegetal (Spanish, exact), 胚珠 (Japanese, exact), Poaceae ovule (narrow), Zea ovule (narrow)
PO:0025074 — embryo sac — saco embrionario (Spanish, exact), 胚嚢 (Japanese, exact)
PO:0025281 — pollen — polen (Spanish, exact), pollen grain (exact), 花粉 (Japanese, exact)

GO:0031507 — involved in — heterochromatin formation
GO:0005515 — enables — protein binding
GO:0043565 — enables — sequence-specific DNA binding
GO:0005634 — located in — nucleus
GO:0042054 — enables — histone methyltransferase activity
GO:0048317 — acts upstream of or within — seed morphogenesis
GO:2000014 — acts upstream of or within — regulation of endosperm development
GO:0006349 — acts upstream of or within — regulation of gene expression by genomic imprinting
GO:0005634 — is active in — nucleus
GO:0009646 — acts upstream of or within — response to absence of light
GO:0003682 — enables — chromatin binding
GO:0046976 — enables — histone H3K27 methyltransferase activity
GO:0045892 — acts upstream of or within — negative regulation of DNA-templated transcription
GO:0010484 — enables — histone H3 acetyltransferase activity
GO:0031519 — part of — PcG protein complex
GO:0006338 — involved in — chromatin remodeling

CS6996 — Autonomous seed development is initiated in absence of fertilization, with a penetrance of about 40-50%; autonomous seeds do not contain an embryo but only endosperm; autonomous endosperm development is accompanied by increase in pistil elongation and ovule size, leading to a small developing seed that contains endosperm. Abnormal development of the endosperm posterior pole with a cyst and nodules larger than in the wild type; ectopic location of nodules in the peripheral endosperm; absence of cellularisation and overproliferation at late stages. Embryos are indistinguishable from wild-type siblings during early stages of embryogenesis, visible differences begin at the late globular stage. Gametophytic maternal effect results in embryo lethality.
CS6997 — Autonomous seed development is initiated in absence of fertilization, with a penetrance of about 40-50%; autonomous seeds do not contain an embryo but only endosperm; autonomous endosperm development is accompanied by increase in pistil elongation and ovule size, leading to a small developing seed that contains endosperm. Abnormal development of the endosperm posterior pole with a cyst and nodules larger than in the wild type; ectopic location of nodules in the peripheral endosperm; absence of cellularisation and overproliferation at late stages. Embryos are indistinguishable from wild-type siblings during early stages of embryogenesis, visible differences begin at the late globular stage. Gametophytic maternal effect results in embryo lethality.
mea-1 — Heterozygous embryos abort if the mutant allele is derived from the female, but develop normally if it is derived from the male. Embryos derived from mutant eggs abort irrespective of the paternal contribution. Thus, the mea mutant displays maternal-effect embryo lethality.
mea-1 — In the homozygous progeny: During early stages of embryogenesis the development of mea-1 embryos is indistinguishable from wild-type siblings in cleared or sectioned specimens. Visible differences between wild-type and mea-1 embryos began at the late globular stage. Globular mea-1 embryos show excess cell proliferation and enlarge radially symmetrical. When wild-type embryos reach the mid to late heart stage, sibling mea-1 embryos are still globular and contain small vacuolated cells with curvilinear cell walls and sometimes irregular cell divisions in the ground tissue and procambium. Suspensor and hypophysis are normal, and cotyledons initiate synchronously as in the wild type. Thus, despite increased cell proliferation and occasional irregular cytokinesis, morphogenetic progression is normal. However, each stage is prolonged and includes more division cycles, and morphogenesis is delayed. As a consequence, giant heart stage mea-1 embryos are present along with late torpedo or cotyledonary stage wild-type embryos. mea-1 heart stage embryos have supernumerary cell layers. When wild-type siblings are fully differentiated, most mea-1 embryos have reached the late heart stage and are up to 10 times larger than normal. mea embryos degenerate during desiccation. These results suggest that mea controls cell proliferation during embryogenesis, allowing morphogenesis to progress normally, albeit slowly. Endosperm development in mea-1 seeds is indistinguishable from that of the wild type at early stages. When cellularization begins normally in wild-type seeds at the transition from the globular to the heart stage, no cellularization is observed in sibling mea-1 seeds. Although nuclear divisions take place more slowly in mea-1 endosperm, the distribution of endosperm nuclei is as in the wild type. Partial cellularization occurs at the micropyle when mea-1 embryos reach the late heart stage in desiccating seeds, but because fewer nuclei have been generated, most of the central cell is devoid of nuclei. Thus, in mea-1 seeds, the development of both fertilization products is delayed but morphogenesis proceeds normally, and it appears that the embryo shows increased cell proliferation at the expense of the endosperm.
mea-1 — The homozygous progeny is embryo-lethal.
mea-2 — Mutant homozygous mea embryo sacs accumulated 45 times more maternal transcripts than wild-type before fertilization, and it persisted after fertilization (7.5 times more transcripts 4 d after pollination.
mea-2 — Similar to non-revertant mea-1 mutant.
mea-2 — The homozygous progeny is embryo-lethal.

Functional Keywords

Literature and News

Gene Resources

Homologs

Sequences

cDNA Sequence

>AT1G02580.2
CTTTGCATTATCCTTTTCACCAACATCAGAGAAGACGAGAAAAAAAGAAGAGGCGAGTGGTTAATGGAGAAGGAAAACCATGAGGACGATGGTGAGGGTTTGCCACCCGAACTAAATCAGATAAAAGAGCAAATCGAAAAGGAGAGATTTCTGCATATCAAGAGAAAATTCGAGCTGAGATACATTCCAAGTGTGGCTACTCATGCTTCACACCATCAATCGTTTGACTTAAACCAGCCCGCTGCAGAGGATGATAATGGAGGAGACAACAAATCACTTTTGTCGAGAATGCAAAACCCACTTCGTCATTTCAGTGCCTCATCTGATTATAATTCTTACGAAGATCAAGGTTATGTTCTTGATGAGGATCAAGATTATGCTCTTGAAGAAGATGTACCATTATTTCTTGATGAAGATGTACCATTATTACCAAGTGTCAAGCTTCCAATTGTTGAGAAGCTACCACGATCCATTACATGGGTCTTCACCAAAAGTAGCCAGCTGATGGCTGAAAGTGATTCTGTGATTGGTAAGAGACAAATCTATTATTTGAATGGTGAGGCACTAGAATTGAGCAGTGAAGAAGATGAGGAAGATGAAGAAGAAGATGAGGAAGAAATCAAGAAAGAAAAATGCGAATTTTCTGAAGATGTAGACCGATTTATATGGACGGTTGGGCAGGACTATGGTTTGGATGATCTGGTCGTGCGGCGTGCTCTCGCCAAGTACCTCGAAGTGGATGTTTCGGACATATTGGAAAGATACAATGAACTCAAGCTTAAGAATGATGGAACTGCTGGTGAGGCTTCTGATTTGACATCCAAGACAATAACTACTGCTTTCCAGGATTTTGCTGATAGACGTCATTGCCGTCGTTGCATGATATTCGATTGTCATATGCATGAGAAGTATGAGCCCGAGTCTAGATCCAGCGAAGACAAATCTAGTTTGTTTGAGGATGAAGATAGACAACCATGCAGTGAGCATTGTTACCTCAAGGTGAGGAGTGTGACAGAAGCTGATCATGTGATGGATAATGATAACTCTATATCAAACAAGATTGTGGTCTCAGATCCAAACAACACTATGTGGACGCCTGTAGAGAAGGATCTTTACTTGAAAGGAATTGAGATATTTGGGAGAAACAGTTGTGATGTTGCATTAAACATACTTCGGGGGCTTAAGACGTGCCTAGAGATTTACAATTACATGCGCGAACAAGATCAATGTACTATGTCATTAGACCTTAACAAAACTACACAAAGACACAATCAGGTTACCAAAAAAGTATCTCGAAAAAGTAGTAGGTCGGTCCGCAAAAAATCGAGACTCCGAAAATATGCTCGTTATCCGCCTGCTTTAAAGAAAACAACTAGTGGAGAAGCTAAGTTTTATAAGCACTACACACCATGCACTTGCAAGTCAAAATGTGGACAGCAATGCCCTTGTTTAACTCACGAAAATTGCTGCGAGAAATATTGCGGGTGCTCAAAGGATTGCAACAATCGCTTTGGAGGATGTAATTGTGCAATTGGCCAATGCACAAATCGACAATGTCCTTGTTTTGCTGCTAATCGTGAATGCGATCCAGATCTTTGTCGGAGTTGTCCTCTTAGCTGTGGAGATGGCACTCTTGGTGAGACACCAGTGCAAATCCAATGCAAGAACATGCAATTCCTCCTTCAAACCAATAAAAAGATTCTCATTGGAAAGTCTGATGTTCATGGATGGGGTGCATTTACATGGGTAAGCAATCATGTAAATATAAGAATAAGTTTAATAGTTATTGGTGCATTCATAACACTTTTTTTTTTTTAAT
>AT1G02580.1
CTTTGCATTATCCTTTTCACCAACATCAGAGAAGACGAGAAAAAAAGAAGAGGCGAGTGGTTAATGGAGAAGGAAAACCATGAGGACGATGGTGAGGGTTTGCCACCCGAACTAAATCAGATAAAAGAGCAAATCGAAAAGGAGAGATTTCTGCATATCAAGAGAAAATTCGAGCTGAGATACATTCCAAGTGTGGCTACTCATGCTTCACACCATCAATCGTTTGACTTAAACCAGCCCGCTGCAGAGGATGATAATGGAGGAGACAACAAATCACTTTTGTCGAGAATGCAAAACCCACTTCGTCATTTCAGTGCCTCATCTGATTATAATTCTTACGAAGATCAAGGTTATGTTCTTGATGAGGATCAAGATTATGCTCTTGAAGAAGATGTACCATTATTTCTTGATGAAGATGTACCATTATTACCAAGTGTCAAGCTTCCAATTGTTGAGAAGCTACCACGATCCATTACATGGGTCTTCACCAAAAGTAGCCAGCTGATGGCTGAAAGTGATTCTGTGATTGGTAAGAGACAAATCTATTATTTGAATGGTGAGGCACTAGAATTGAGCAGTGAAGAAGATGAGGAAGATGAAGAAGAAGATGAGGAAGAAATCAAGAAAGAAAAATGCGAATTTTCTGAAGATGTAGACCGATTTATATGGACGGTTGGGCAGGACTATGGTTTGGATGATCTGGTCGTGCGGCGTGCTCTCGCCAAGTACCTCGAAGTGGATGTTTCGGACATATTGGAAAGATACAATGAACTCAAGCTTAAGAATGATGGAACTGCTGGTGAGGCTTCTGATTTGACATCCAAGACAATAACTACTGCTTTCCAGGATTTTGCTGATAGACGTCATTGCCGTCGTTGCATGATATTCGATTGTCATATGCATGAGAAGTATGAGCCCGAGTCTAGATCCAGCGAAGACAAATCTAGTTTGTTTGAGGATGAAGATAGACAACCATGCAGTGAGCATTGTTACCTCAAGGTGAGGAGTGTGACAGAAGCTGATCATGTGATGGATAATGATAACTCTATATCAAACAAGATTGTGGTCTCAGATCCAAACAACACTATGTGGACGCCTGTAGAGAAGGATCTTTACTTGAAAGGAATTGAGATATTTGGGAGAAACAGTTGTGATGTTGCATTAAACATACTTCGGGGGCTTAAGACGTGCCTAGAGATTTACAATTACATGCGCGAACAAGATCAATGTACTATGTCATTAGACCTTAACAAAACTACACAAAGACACAATCAGGTTACCAAAAAAGTATCTCGAAAAAGTAGTAGGTCGGTCCGCAAAAAATCGAGACTCCGAAAATATGCTCGTTATCCGCCTGCTTTAAAGAAAACAACTAGTGGAGAAGCTAAGTTTTATAAGCACTACACACCATGCACTTGCAAGTCAAAATGTGGACAGCAATGCCCTTGTTTAACTCACGAAAATTGCTGCGAGAAATATTGCGGGTGCTCAAAGGATTGCAACAATCGCTTTGGAGGATGTAATTGTGCAATTGGCCAATGCACAAATCGACAATGTCCTTGTTTTGCTGCTAATCGTGAATGCGATCCAGATCTTTGTCGGAGTTGTCCTCTTAGCTGTGGAGATGGCACTCTTGGTGAGACACCAGTGCAAATCCAATGCAAGAACATGCAATTCCTCCTTCAAACCAATAAAAAGATTCTCATTGGAAAGTCTGATGTTCATGGATGGGGTGCATTTACATGGGTAAGCAATCATGTAAATATAAGAATAAGTTTAATAGTTATTGGTGCATTCATAACACTTTTTTTTTTTTAAT

CDS Sequence

>AT1G02580.2
ATGGAGAAGGAAAACCATGAGGACGATGGTGAGGGTTTGCCACCCGAACTAAATCAGATAAAAGAGCAAATCGAAAAGGAGAGATTTCTGCATATCAAGAGAAAATTCGAGCTGAGATACATTCCAAGTGTGGCTACTCATGCTTCACACCATCAATCGTTTGACTTAAACCAGCCCGCTGCAGAGGATGATAATGGAGGAGACAACAAATCACTTTTGTCGAGAATGCAAAACCCACTTCGTCATTTCAGTGCCTCATCTGATTATAATTCTTACGAAGATCAAGGTTATGTTCTTGATGAGGATCAAGATTATGCTCTTGAAGAAGATGTACCATTATTTCTTGATGAAGATGTACCATTATTACCAAGTGTCAAGCTTCCAATTGTTGAGAAGCTACCACGATCCATTACATGGGTCTTCACCAAAAGTAGCCAGCTGATGGCTGAAAGTGATTCTGTGATTGGTAAGAGACAAATCTATTATTTGAATGGTGAGGCACTAGAATTGAGCAGTGAAGAAGATGAGGAAGATGAAGAAGAAGATGAGGAAGAAATCAAGAAAGAAAAATGCGAATTTTCTGAAGATGTAGACCGATTTATATGGACGGTTGGGCAGGACTATGGTTTGGATGATCTGGTCGTGCGGCGTGCTCTCGCCAAGTACCTCGAAGTGGATGTTTCGGACATATTGGAAAGATACAATGAACTCAAGCTTAAGAATGATGGAACTGCTGGTGAGGCTTCTGATTTGACATCCAAGACAATAACTACTGCTTTCCAGGATTTTGCTGATAGACGTCATTGCCGTCGTTGCATGATATTCGATTGTCATATGCATGAGAAGTATGAGCCCGAGTCTAGATCCAGCGAAGACAAATCTAGTTTGTTTGAGGATGAAGATAGACAACCATGCAGTGAGCATTGTTACCTCAAGGTGAGGAGTGTGACAGAAGCTGATCATGTGATGGATAATGATAACTCTATATCAAACAAGATTGTGGTCTCAGATCCAAACAACACTATGTGGACGCCTGTAGAGAAGGATCTTTACTTGAAAGGAATTGAGATATTTGGGAGAAACAGTTGTGATGTTGCATTAAACATACTTCGGGGGCTTAAGACGTGCCTAGAGATTTACAATTACATGCGCGAACAAGATCAATGTACTATGTCATTAGACCTTAACAAAACTACACAAAGACACAATCAGGTTACCAAAAAAGTATCTCGAAAAAGTAGTAGGTCGGTCCGCAAAAAATCGAGACTCCGAAAATATGCTCGTTATCCGCCTGCTTTAAAGAAAACAACTAGTGGAGAAGCTAAGTTTTATAAGCACTACACACCATGCACTTGCAAGTCAAAATGTGGACAGCAATGCCCTTGTTTAACTCACGAAAATTGCTGCGAGAAATATTGCGGGTGCTCAAAGGATTGCAACAATCGCTTTGGAGGATGTAATTGTGCAATTGGCCAATGCACAAATCGACAATGTCCTTGTTTTGCTGCTAATCGTGAATGCGATCCAGATCTTTGTCGGAGTTGTCCTCTTAGCTGTGGAGATGGCACTCTTGGTGAGACACCAGTGCAAATCCAATGCAAGAACATGCAATTCCTCCTTCAAACCAATAAAAAGATTCTCATTGGAAAGTCTGATGTTCATGGATGGGGTGCATTTACATGGGTAAGCAATCATGTAAATATAAGAATAAGTTTAATAGTTATTGGTGCATTCATAACACTTTTTTTTTTTTAA
>AT1G02580.1
ATGGAGAAGGAAAACCATGAGGACGATGGTGAGGGTTTGCCACCCGAACTAAATCAGATAAAAGAGCAAATCGAAAAGGAGAGATTTCTGCATATCAAGAGAAAATTCGAGCTGAGATACATTCCAAGTGTGGCTACTCATGCTTCACACCATCAATCGTTTGACTTAAACCAGCCCGCTGCAGAGGATGATAATGGAGGAGACAACAAATCACTTTTGTCGAGAATGCAAAACCCACTTCGTCATTTCAGTGCCTCATCTGATTATAATTCTTACGAAGATCAAGGTTATGTTCTTGATGAGGATCAAGATTATGCTCTTGAAGAAGATGTACCATTATTTCTTGATGAAGATGTACCATTATTACCAAGTGTCAAGCTTCCAATTGTTGAGAAGCTACCACGATCCATTACATGGGTCTTCACCAAAAGTAGCCAGCTGATGGCTGAAAGTGATTCTGTGATTGGTAAGAGACAAATCTATTATTTGAATGGTGAGGCACTAGAATTGAGCAGTGAAGAAGATGAGGAAGATGAAGAAGAAGATGAGGAAGAAATCAAGAAAGAAAAATGCGAATTTTCTGAAGATGTAGACCGATTTATATGGACGGTTGGGCAGGACTATGGTTTGGATGATCTGGTCGTGCGGCGTGCTCTCGCCAAGTACCTCGAAGTGGATGTTTCGGACATATTGGAAAGATACAATGAACTCAAGCTTAAGAATGATGGAACTGCTGGTGAGGCTTCTGATTTGACATCCAAGACAATAACTACTGCTTTCCAGGATTTTGCTGATAGACGTCATTGCCGTCGTTGCATGATATTCGATTGTCATATGCATGAGAAGTATGAGCCCGAGTCTAGATCCAGCGAAGACAAATCTAGTTTGTTTGAGGATGAAGATAGACAACCATGCAGTGAGCATTGTTACCTCAAGGTGAGGAGTGTGACAGAAGCTGATCATGTGATGGATAATGATAACTCTATATCAAACAAGATTGTGGTCTCAGATCCAAACAACACTATGTGGACGCCTGTAGAGAAGGATCTTTACTTGAAAGGAATTGAGATATTTGGGAGAAACAGTTGTGATGTTGCATTAAACATACTTCGGGGGCTTAAGACGTGCCTAGAGATTTACAATTACATGCGCGAACAAGATCAATGTACTATGTCATTAGACCTTAACAAAACTACACAAAGACACAATCAGGTTACCAAAAAAGTATCTCGAAAAAGTAGTAGGTCGGTCCGCAAAAAATCGAGACTCCGAAAATATGCTCGTTATCCGCCTGCTTTAAAGAAAACAACTAGTGGAGAAGCTAAGTTTTATAAGCACTACACACCATGCACTTGCAAGTCAAAATGTGGACAGCAATGCCCTTGTTTAACTCACGAAAATTGCTGCGAGAAATATTGCGGGTGCTCAAAGGATTGCAACAATCGCTTTGGAGGATGTAATTGTGCAATTGGCCAATGCACAAATCGACAATGTCCTTGTTTTGCTGCTAATCGTGAATGCGATCCAGATCTTTGTCGGAGTTGTCCTCTTAGCTGTGGAGATGGCACTCTTGGTGAGACACCAGTGCAAATCCAATGCAAGAACATGCAATTCCTCCTTCAAACCAATAAAAAGATTCTCATTGGAAAGTCTGATGTTCATGGATGGGGTGCATTTACATGGGTAAGCAATCATGTAAATATAAGAATAAGTTTAATAGTTATTGGTGCATTCATAACACTTTTTTTTTTTTAA

Protein Sequence

>AT1G02580.2
MEKENHEDDGEGLPPELNQIKEQIEKERFLHIKRKFELRYIPSVATHASHHQSFDLNQPAAEDDNGGDNKSLLSRMQNPLRHFSASSDYNSYEDQGYVLDEDQDYALEEDVPLFLDEDVPLLPSVKLPIVEKLPRSITWVFTKSSQLMAESDSVIGKRQIYYLNGEALELSSEEDEEDEEEDEEEIKKEKCEFSEDVDRFIWTVGQDYGLDDLVVRRALAKYLEVDVSDILERYNELKLKNDGTAGEASDLTSKTITTAFQDFADRRHCRRCMIFDCHMHEKYEPESRSSEDKSSLFEDEDRQPCSEHCYLKVRSVTEADHVMDNDNSISNKIVVSDPNNTMWTPVEKDLYLKGIEIFGRNSCDVALNILRGLKTCLEIYNYMREQDQCTMSLDLNKTTQRHNQVTKKVSRKSSRSVRKKSRLRKYARYPPALKKTTSGEAKFYKHYTPCTCKSKCGQQCPCLTHENCCEKYCGCSKDCNNRFGGCNCAIGQCTNRQCPCFAANRECDPDLCRSCPLSCGDGTLGETPVQIQCKNMQFLLQTNKKILIGKSDVHGWGAFTWVSNHVNIRISLIVIGAFITLFFF
>AT1G02580.1
MEKENHEDDGEGLPPELNQIKEQIEKERFLHIKRKFELRYIPSVATHASHHQSFDLNQPAAEDDNGGDNKSLLSRMQNPLRHFSASSDYNSYEDQGYVLDEDQDYALEEDVPLFLDEDVPLLPSVKLPIVEKLPRSITWVFTKSSQLMAESDSVIGKRQIYYLNGEALELSSEEDEEDEEEDEEEIKKEKCEFSEDVDRFIWTVGQDYGLDDLVVRRALAKYLEVDVSDILERYNELKLKNDGTAGEASDLTSKTITTAFQDFADRRHCRRCMIFDCHMHEKYEPESRSSEDKSSLFEDEDRQPCSEHCYLKVRSVTEADHVMDNDNSISNKIVVSDPNNTMWTPVEKDLYLKGIEIFGRNSCDVALNILRGLKTCLEIYNYMREQDQCTMSLDLNKTTQRHNQVTKKVSRKSSRSVRKKSRLRKYARYPPALKKTTSGEAKFYKHYTPCTCKSKCGQQCPCLTHENCCEKYCGCSKDCNNRFGGCNCAIGQCTNRQCPCFAANRECDPDLCRSCPLSCGDGTLGETPVQIQCKNMQFLLQTNKKILIGKSDVHGWGAFTWVSNHVNIRISLIVIGAFITLFFF