Gene Details:

• Gene ID: AT1G01370
• Gene Symbol: CENH3, HTR12
• Gene Name: CENTROMERIC HISTONE H3
• Description: Histone superfamily protein;(source:Araport11)
• TAIR Accession: locus:2035252
• Genome: Araport11_genome_release
• Species: Arabidopsis thaliana

Transcripts:

• AT1G01370.1     AT1G01370.2     AT1G01370.3     AT1G01370.4

Plant Ontology Annotations:

• PO:0009071  — anther wall tapetum — pollen sac tapetum (exact), portion of anther wall tapetal tissue (exact), tapete (Spanish, exact), 葯壁タペート組織 (Japanese, exact), Poaceae tapetum (narrow), Zea tapetum (narrow)
• PO:0009010  — seed — semilla (Spanish, exact), 種子 (Japanese, exact), pyrene (narrow), diaspore (broad)
• PO:0009032  — petal — pétalo (Spanish, exact), 花弁 (Japanese, exact)
• PO:0009005  — root — raíz (Spanish, exact), radices (exact, plural), radix (exact), 根 (Japanese, exact), aerial root (narrow), climbing root (narrow)
• PO:0009025  — vascular leaf — foliage leaf (exact), hoja vascular (Spanish, exact), leaf, vascular (exact), vascular leaves (exact, plural), 維管束のある葉, または維管束植物の葉 (Japanese, exact), crozier (related), macrophyll (related), megaphyll (related), ascidia (narrow), ascidium (narrow), fiddlehead (narrow), frond (narrow), needle-like leaf (narrow), pitcher (narrow), pitcher blade (narrow), pitcher-blade (narrow), scale-like leaf (narrow), sterile frond (narrow), trophophyll (narrow)
• PO:0009046  — flower — flor (Spanish, exact), 花 (Japanese, exact), floret (related), Asteraceae floret (narrow), basal flower (narrow), double flower (narrow), hermaphrodite flower (narrow), monoclinous flower (narrow), perfect flower (narrow)
• PO:0009049  — inflorescence — inflorescencia (Spanish, exact), 花序 (Japanese, exact), Triticeae spike (narrow)
• PO:0020048  — microspore — microspora (Spanish, exact), 小胞子 (Japanese, exact), Poaceae microspore (narrow), Zea microspore (narrow)
• PO:0000084  — plant sperm cell — célula espermática o esperma (Spanish, exact), male gamete (exact), microgamete (exact), 植物精子細胞 (Japanese, exact), sperm nucleus (related), sperm cell (broad)
• PO:0000293  — guard cell — célula guardiana (Spanish, exact), occlusive cell (exact), 孔辺細胞 (Japanese, exact)

Gene Ontology:

• GO:0005515  — enables — protein binding
• GO:0051321  — acts upstream of or within — meiotic cell cycle
• GO:0051307  — acts upstream of or within — meiotic chromosome separation
• GO:0000775  — located in — chromosome, centromeric region
• GO:0005634  — located in — nucleus
• GO:0005634  — is active in — nucleus
• GO:0046982  — enables — protein heterodimerization activity
• GO:0000785  — located in — chromatin
• GO:0034508  — acts upstream of or within — centromere complex assembly
• GO:0009567  — acts upstream of or within — double fertilization forming a zygote and endosperm
• GO:0051301  — acts upstream of or within — cell division
• GO:0030527  — enables — structural constituent of chromatin

Germplasm Phenotype:

• CS66982  — cenh3-1 GFP-tailswap progeny have short stature, altered rosette leaf morphology and a high degree of male sterility. Other progeny have a wild type phenotype.
• SALK_036200  — The mutant shows ABA insensitivity in stomatal movement, including promotion of stomatal closure and inhibition of stomatal opening. The detached leaves of the mutant lose more water than those of the wild-type plants under dehydration condition; both young seedlings and mature plants of the mutant have lower capacity to conserve water during drought stress in comparison with wild-type plants. The ROS levels increase in the mutant in comparison with wild-type plants in both the whole leaves and in guard cells. Treatment with low concentrations of ABA reduces ROS levels in both whole leaves(1 to 10 uM ABA application) and in guard cells(5 uM ABA application) in the mutant plants.

Function-related keywords:

• anther wall tapetum ,  seed ,  petal ,  root ,  vascular leaf ,  flower ,  inflorescence ,  microspore ,  plant sperm cell ,  guard cell

Literature:

• The GUS reporter-aided analysis of the promoter activities of Arabidopsis ACC synthase genes AtACS4, AtACS5, and AtACS7 induced by hormones and stresses.   DOI:  10.1093/jxb/eri083 ;  PMID:  15699063
• Phosphorylation of 1-aminocyclopropane-1-carboxylic acid synthase by MPK6, a stress-responsive mitogen-activated protein kinase, induces ethylene biosynthesis in Arabidopsis.   DOI:  10.1105/tpc.104.026609 ;  PMID:  15539472
• AUXIN RESPONSE FACTOR 2 (ARF2): a pleiotropic developmental regulator.   DOI:  10.1111/j.1365-313X.2005.02426.x ;  PMID:  15960614
• MAPK phosphorylation-induced stabilization of ACS6 protein is mediated by the non-catalytic C-terminal domain, which also contains the cis-determinant for rapid degradation by the 26S proteasome pathway.   DOI:  10.1111/j.1365-313X.2008.03404.x ;  PMID:  18182027
• Overexpression of wound-responsive RNA-binding proteins induces leaf senescence and hypersensitive-like cell death.   DOI:  10.1111/j.1469-8137.2008.02557.x ;  PMID:  18705666
• A combinatorial interplay among the 1-aminocyclopropane-1-carboxylate isoforms regulates ethylene biosynthesis in Arabidopsis thaliana.   DOI:  10.1534/genetics.109.107102 ;  PMID:  19752216
• Mitogen-activated protein kinase 3 and 6 regulate Botrytis cinerea-induced ethylene production in Arabidopsis.   DOI:  10.1111/j.1365-313X.2010.04318.x ;  PMID:  20659280
• Protein phosphatase 2A controls ethylene biosynthesis by differentially regulating the turnover of ACC synthase isoforms.   DOI:  10.1371/journal.pgen.1001370 ;  PMID:  21533019
• The ethylene response factor AtERF11 that is transcriptionally modulated by the bZIP transcription factor HY5 is a crucial repressor for ethylene biosynthesis in Arabidopsis.   DOI:  10.1111/j.1365-313X.2011.04670.x ;  PMID:  21645149
• Dual-level regulation of ACC synthase activity by MPK3/MPK6 cascade and its downstream WRKY transcription factor during ethylene induction in Arabidopsis.   DOI:  10.1371/journal.pgen.1002767 ;  PMID:  22761583
• Antiphase light and temperature cycles affect PHYTOCHROME B-controlled ethylene sensitivity and biosynthesis, limiting leaf movement and growth of Arabidopsis.   DOI:  10.1104/pp.113.221648 ;  PMID:  23979970
• Ethylene promotes germination of Arabidopsis seed under salinity by decreasing reactive oxygen species: evidence for the involvement of nitric oxide simulated by sodium nitroprusside.   DOI:  10.1016/j.plaphy.2013.10.003 ;  PMID:  24148906
• Plant hormones in defense response of Brassica napus to Sclerotinia sclerotiorum reassessing the role of salicylic acid in the interaction with a necrotroph.   DOI:  10.1016/j.plaphy.2014.04.019 ;  PMID:  24837830
• Cadmium-induced ethylene production and responses in Arabidopsis thaliana rely on ACS2 and ACS6 gene expression.   DOI:  10.1186/s12870-014-0214-6 ;  PMID:  25082369
• EIN3 and ORE1 Accelerate Degreening during Ethylene-Mediated Leaf Senescence by Directly Activating Chlorophyll Catabolic Genes in Arabidopsis.   DOI:  10.1371/journal.pgen.1005399 ;  PMID:  26218222
• Multilayered Regulation of Ethylene Induction Plays a Positive Role in Arabidopsis Resistance against Pseudomonas syringae.   DOI:  10.1104/pp.15.00659 ;  PMID:  26265775
• and oligogalacturonide-induced immunity requires calcium-dependent protein kinases.   DOI:  10.1111/tpj.13057 ;  PMID:  26485342
• Glutathione Regulates 1-Aminocyclopropane-1-Carboxylate Synthase Transcription via WRKY33 and 1-Aminocyclopropane-1-Carboxylate Oxidase by Modulating Messenger RNA Stability to Induce Ethylene Synthesis during Stress.   DOI:  10.1104/pp.15.01543 ;  PMID:  26463088
• MPK3/MPK6 are involved in iron deficiency-induced ethylene production in Arabidopsis.   DOI:  10.3389/fpls.2015.00953 ;  PMID:  26579185
• NO Promotes Seed Germination and Seedling Growth Under High Salt May Depend on EIN3 Protein in Arabidopsis.   DOI:  10.3389/fpls.2015.01203 ;  PMID:  26779234
• Regulation of the turnover of ACC synthases by phytohormones and heterodimerization in Arabidopsis.   DOI:  10.1111/tpj.13585 ;  PMID:  28440947
• Mitogen-activated protein kinases and calcium-dependent protein kinases are involved in wounding-induced ethylene biosynthesis in Arabidopsis thaliana.   DOI:  10.1111/pce.12984 ;  PMID:  28543054
• Novel functions of the Arabidopsis transcription factor TCP5 in petal development and ethylene biosynthesis.   DOI:  10.1111/tpj.13904 ;  PMID:  29570883
• Diurnal down-regulation of ethylene biosynthesis mediates biomass heterosis.   DOI:  10.1073/pnas.1722068115 ;  PMID:  29735680
• Aminocyclopropane-1-carboxylic acid is a key regulator of guard mother cell terminal division in Arabidopsis thaliana.   DOI:  10.1093/jxb/ery413 ;  PMID:  30462272
• Protein phosphatase 2A alleviates cadmium toxicity by modulating ethylene production in Arabidopsis thaliana.   DOI:  10.1111/pce.13716 ;  PMID:  31916592
• Target of Rapamycin (TOR) Negatively Regulates Ethylene Signals in Arabidopsis.   DOI:  10.3390/ijms21082680 ;  PMID:  32290539
• The ubiquitin E3 ligase SR1 modulates the submergence response by degrading phosphorylated WRKY33 in Arabidopsis.   DOI:  10.1093/plcell/koab062 ;  PMID:  33616649
• Activating the MYB51 and MYB122 to upregulate the transcription of glucosinolates biosynthesis genes by copper ions in Arabidopsis.   DOI:  10.1016/j.plaphy.2021.03.025 ;  PMID:  33756355
• A C-terminal fragment of Arabidopsis OXIDATIVE STRESS 2 can play a positive role in salt tolerance.   DOI:  10.1016/j.bbrc.2021.03.127 ;  PMID:  33836344
• Activation of 1-Aminocyclopropane-1-Carboxylic Acid Synthases Sets Stomatal Density and Clustered Ratio on Leaf Epidermis of Arabidopsis in Response to Drought.   DOI:  10.3389/fpls.2021.758785 ;  PMID:  34938306
• Arabidopsis WRKY71 regulates ethylene-mediated leaf senescence by directly activating EIN2, ORE1 and ACS2 genes.   DOI:  10.1111/tpj.15433 ;  PMID:  34296474
• Phosphorylation of an ethylene response factor by MPK3/MPK6 mediates negative feedback regulation of pathogen-induced ethylene biosynthesis in Arabidopsis.   DOI:  10.1016/j.jgg.2022.04.012 ;  PMID:  35562093
• Wheat Elongator Subunit 4 Negatively Regulates Freezing Tolerance by Regulating Ethylene Accumulation.   DOI:  10.3390/ijms23147634 ;  PMID:  35886984
• Heavy metal-associated isoprenylated plant protein (HIPP): characterization of a family of proteins exclusive to plants.   DOI:  10.1111/febs.12159 ;  PMID:  23368984
• Heavy Metal Stress-Associated Proteins in Rice and Arabidopsis: Genome-Wide Identification, Phylogenetics, Duplication, and Expression Profiles Analysis.   DOI:  10.3389/fgene.2020.00477 ;  PMID:  32457808
• Genetic control of trichome branch number in Arabidopsis: the roles of the FURCA loci.   DOI:  10.1242/dev.126.24.5547 ;  PMID:  10572032
• The CURLY LEAF gene controls both division and elongation of cells during the expansion of the leaf blade in Arabidopsis thaliana.   DOI:  10.1007/s004250050389 ;  PMID:  9736998
• Genetic analyses of the formation of the serrated margin of leaf blades in Arabidopsis: combination of a mutational analysis of leaf morphogenesis with the characterization of a specific marker gene expressed in hydathodes and stipules.   DOI:  10.1007/s004380050565 ;  PMID:  9393447
• Two independent and polarized processes of cell elongation regulate leaf blade expansion in Arabidopsis thaliana (L.) Heynh.   DOI:  10.1242/dev.122.5.1589 ;  PMID:  8625845
• The ANGUSTIFOLIA gene of Arabidopsis, a plant CtBP gene, regulates leaf-cell expansion, the arrangement of cortical microtubules in leaf cells and expression of a gene involved in cell-wall formation.   DOI:  10.1093/emboj/21.6.1267 ;  PMID:  11889033
• The leaf index: heteroblasty, natural variation, and the genetic control of polar processes of leaf expansion.   DOI:  10.1093/pcp/pcf051 ;  PMID:  11978864
• Trichome morphogenesis: a cell-cycle perspective.   DOI:  10.1098/rstb.2002.1087 ;  PMID:  12079678
• DRL1, a homolog of the yeast TOT4/KTI12 protein, has a function in meristem activity and organ growth in plants.   DOI:  10.1105/tpc.007062 ;  PMID:  12615938
• The cell morphogenesis gene ANGUSTIFOLIA encodes a CtBP/BARS-like protein and is involved in the control of the microtubule cytoskeleton.   DOI:  10.1093/emboj/21.6.1280 ;  PMID:  11889034
• Characterization of a member of the AN subfamily, IAN, from Ipomoea nil.   DOI:  10.1093/pcp/pci020 ;  PMID:  15659438
• Structurally related Arabidopsis ANGUSTIFOLIA is functionally distinct from the transcriptional corepressor CtBP.   DOI:  10.1007/s00427-007-0186-8 ;  PMID:  17972097
• Isolation and characterization of the Larix gmelinii ANGUSTIFOLIA (LgAN) gene.   DOI:  10.1007/s00425-008-0762-9 ;  PMID:  18560884
• Tissue layer specific regulation of leaf length and width in Arabidopsis as revealed by the cell autonomous action of ANGUSTIFOLIA.   DOI:  10.1111/j.1365-313X.2009.04050.x ;  PMID:  19843316
• ANGUSTIFOLIA, a plant homolog of CtBP/BARS, functions outside the nucleus.   DOI:  10.1111/j.1365-313X.2011.04731.x ;  PMID:  21801251
• ANGUSTIFOLIA is a central component of tissue morphogenesis mediated by the atypical receptor-like kinase STRUBBELIG.   DOI:  10.1186/1471-2229-13-16 ;  PMID:  23368817
• The cell morphogenesis ANGUSTIFOLIA (AN) gene, a plant homolog of CtBP/BARS, is involved in abiotic and biotic stress response in higher plants.   DOI:  10.1186/1471-2229-13-79 ;  PMID:  23672620
• ANGUSTIFOLIA mediates one of the multiple SCRAMBLED signaling pathways regulating cell growth pattern in Arabidopsis thaliana.   DOI:  10.1016/j.bbrc.2015.08.067 ;  PMID:  26296462
• TCS1, a Microtubule-Binding Protein, Interacts with KCBP/ZWICHEL to Regulate Trichome Cell Shape in Arabidopsis thaliana.   DOI:  10.1371/journal.pgen.1006266 ;  PMID:  27768706
• Screening Arabidopsis mutants in genes useful for phytoremediation.   DOI:  10.1016/j.jhazmat.2017.04.021 ;  PMID:  28441590
• ANGUSTIFOLIA, a Plant Homolog of CtBP/BARS Localizes to Stress Granules and Regulates Their Formation.   DOI:  10.3389/fpls.2017.01004 ;  PMID:  28659951
• Reactive oxygen species mediate conical cell shaping in Arabidopsis thaliana petals.   DOI:  10.1371/journal.pgen.1007705 ;  PMID:  30296269

Sequences: