Gene Details:

• Gene ID: AT1G01040
• Gene Symbol: ASU1, ATDCL1, CAF, DCL1, EMB60, EMB76, SIN1, SUS1
• Gene Name: ABNORMAL SUSPENSOR 1, DICER-LIKE 1, CARPEL FACTORY, dicer-like 1, EMBRYO DEFECTIVE 60, EMBRYO DEFECTIVE 76, SHORT INTEGUMENTS 1, SUSPENSOR 1
• Description: dicer-like 1;(source:Araport11)
• TAIR Accession: locus:2200960
• Genome: Araport11_genome_release
• Species: Arabidopsis thaliana

Transcripts:

• AT1G01040.1     AT1G01040.2

Plant Ontology Annotations:

• PO:0000229  — flower meristem — floral meristem (exact), mersitema floral (Spanish, exact), 花芽分裂組織 (Japanese, exact), floral apical meristem (related), Poaceae floret meristem (narrow), ear floret meristem (narrow), floret meristem (narrow), tassel floret meristem (narrow)
• PO:0009009  — plant embryo — embrión (Spanish, exact), 植物胚 (Japanese, exact), germ (related), embryo (broad)
• PO:0020003  — plant ovule — óvulo vegetal (Spanish, exact), 胚珠 (Japanese, exact), Poaceae ovule (narrow), Zea ovule (narrow)
• PO:0000013  — cauline leaf — hoja caulinar (Spanish, exact), 茎生葉、茎葉 (Japanese, exact)
• PO:0000230  — inflorescence meristem — meristema de la inflorescencia (Spanish, exact), 花序分裂組織 (Japanese, exact)
• PO:0009010  — seed — semilla (Spanish, exact), 種子 (Japanese, exact), pyrene (narrow), diaspore (broad)
• PO:0009030  — carpel — carpelo (Spanish, exact), 心皮 (Japanese, exact), Poaceae carpel (narrow), Zea carpel (narrow), pistil (broad)
• PO:0009032  — petal — pétalo (Spanish, exact), 花弁 (Japanese, exact)
• PO:0009047  — stem — caña (Spanish, exact), culm (exact), eje primario (Spanish, exact), primary axis (exact), primary stem (exact), tallo (Spanish, exact), tronco (Spanish, exact), 茎 (Japanese, exact), bole (narrow), cane (narrow), caudex (narrow), caudices (narrow), core (narrow), primocane (narrow), scape (narrow), stalk (narrow), trunk (narrow)
• PO:0025281  — pollen — polen (Spanish, exact), pollen grain (exact), 花粉 (Japanese, exact)
• PO:0000084  — plant sperm cell — célula espermática o esperma (Spanish, exact), male gamete (exact), microgamete (exact), 植物精子細胞 (Japanese, exact), sperm nucleus (related), sperm cell (broad)
• PO:0000293  — guard cell — célula guardiana (Spanish, exact), occlusive cell (exact), 孔辺細胞 (Japanese, exact)

Gene Ontology:

• GO:0009616  — acts upstream of or within — RNAi-mediated antiviral immune response
• GO:0006396  — acts upstream of or within — RNA processing
• GO:0006364  — involved in — rRNA processing
• GO:0048317  — acts upstream of or within — seed morphogenesis
• GO:0010599  — acts upstream of or within — lsiRNA processing
• GO:0005515  — enables — protein binding
• GO:0010098  — acts upstream of or within — suspensor development
• GO:0010228  — acts upstream of or within — vegetative to reproductive phase transition of meristem
• GO:0000911  — acts upstream of or within — cytokinesis by cell plate formation
• GO:0035279  — acts upstream of or within — miRNA-mediated gene silencing by mRNA destabilization
• GO:0009908  — acts upstream of or within — flower development
• GO:0035196  — acts upstream of or within — miRNA processing
• GO:0005737  — is active in — cytoplasm
• GO:0031053  — acts upstream of or within — primary miRNA processing
• GO:0004525  — enables — ribonuclease III activity
• GO:0010267  — acts upstream of or within — ta-siRNA processing
• GO:0009880  — acts upstream of or within — embryonic pattern specification
• GO:0005634  — located in — nucleus
• GO:2000034  — acts upstream of or within — regulation of seed maturation
• GO:0005737  — located in — cytoplasm
• GO:0030422  — involved in — siRNA processing
• GO:0003723  — enables — RNA binding
• GO:0010445  — located in — nuclear dicing body
• GO:0003725  — enables — double-stranded RNA binding
• GO:0003677  — enables — DNA binding
• GO:0005634  — is active in — nucleus

Germplasm Phenotype:

• CS16068  — embryo defective; developmental arrest of mutant embryos, altered suspensor.
• CS16069  — embryo defective; developmental arrest of mutant embryos, altered suspensor.
• CS16070  — embryo defective; developmental arrest of mutant embryos, altered suspensor.
• CS16071  — embryo defective; developmental arrest of mutant embryos, altered suspensor.
• CS24092  — embryo defective; globular
• CS24094  — embryo defective; globular
• CS3089  — female sterile; altered ovule development; integuments fail to cover nucellus; reduced plant height; reduced length in inflorescence internodes; reduced levels of pollen, smaller leaves; late flowering, slow growth.
• CS3828  — Increased abundance of miRNA precursors.
• CS3828  — indeterminate floral meristems, producing extra whorls of stamens and an indefinite number of carpels; unregulated cell division in the center of the flower with normal floral organ identity; plants also show other developmental defects including absence of axillary inflorescence meristems and abnormally shaped cotyledons, leaves, sepals, stamens and carpels
• CS6338  — developmental arrest of mutant embryos occurs at globular stage; white to pale green seeds; pale yellow-green embryo; 23.5% mutant; 56.9% aborted seeds in top half of silique.
• CS66326  — dcl1 mutant-like defects in embryo development in 17% of the selfed progeny. Partial supression of the early embryonic dcl1 phenotype.
• CS66327  — dcl1 mutant-like defects in embryo development in 25% of the selfed progeny. Full penetrance of the dcl1 phenotype.
• CS66328  — Supression of dcl1 phenotypes in early stages of embryo development (globular and early heart stage). Full penetrance of dcl1 phenotype in later stages (late heart and torpedo stage).
• CS68113  — Homozygous mutants are embryo lethal. Early embryos of homozygous mutants accumulate more chlorophyll, mature earlier than the wild-type, and have abnormal patterns of cell division. A second segregating T-DNA insertion slightly increases carpel number.
• CS6953  — Altered ovule development; integuments fail to cover nucellus; female sterile; reduced levels of pollen. Smaller leaves than wild type; late flowering; slow growth; reduced length of inflorescence internodes; reduced plant height.
• CS84713  — developmental arrest of mutant embryos occurs at globular stage, altered suspensor; white to pale yellow-green seeds; white to pale yellow-green embryo; 24.4% mutant; 50.5% aborted seeds in top half of silique.
• CS84714  — developmental arrest of mutant embryos occurs at globular stage, abnormally large suspensor; pale yellow-green seeds; white embryo; 25.8% mutant; 49.3% aborted seeds in top half of silique.

Function-related keywords:

• flower meristem ,  plant embryo ,  plant ovule ,  cauline leaf ,  inflorescence meristem ,  seed ,  carpel ,  petal ,  stem ,  pollen ,  plant sperm cell ,  guard cell

Literature:

• Disruption of an RNA helicase/RNAse III gene in Arabidopsis causes unregulated cell division in floral meristems.   DOI:  10.1242/dev.126.23.5231 ;  PMID:  10556049
• Maternal effects of the short integument mutation on embryo development in Arabidopsis.   DOI:  10.1006/dbio.1996.0309 ;  PMID:  8948599
• SHORT INTEGUMENT (SIN1), a gene required for ovule development in Arabidopsis, also controls flowering time.   DOI:  10.1242/dev.122.9.2631 ;  PMID:  8787738
• sin 1, a mutation affecting female fertility in Arabidopsis, interacts with mod 1, its recessive modifier.   DOI:  10.1093/genetics/137.4.1101 ;  PMID:  7982564
• MicroRNAs in plants.   DOI:  10.1101/gad.1004402 ;  PMID:  12101121
• Embryonic Lethals and T-DNA Insertional Mutagenesis in Arabidopsis.   DOI:  10.1105/tpc.3.2.149 ;  PMID:  12324593
• Ovule Development in Wild-Type Arabidopsis and Two Female-Sterile Mutants.   DOI:  10.1105/tpc.4.10.1237 ;  PMID:  12297633
• CARPEL FACTORY, a Dicer homolog, and HEN1, a novel protein, act in microRNA metabolism in Arabidopsis thaliana.   DOI:  10.1016/s0960-9822(02)01017-5 ;  PMID:  12225663
• DICER-LIKE1: blind men and elephants in Arabidopsis development.   DOI:  10.1016/s1360-1385(02)02355-5 ;  PMID:  12417148
• SHORT INTEGUMENTS1/SUSPENSOR1/CARPEL FACTORY, a Dicer homolog, is a maternal effect gene required for embryo development in Arabidopsis.   DOI:  10.1104/pp.003491 ;  PMID:  12376646
• Posttranscriptional gene silencing is not compromised in the Arabidopsis CARPEL FACTORY (DICER-LIKE1) mutant, a homolog of Dicer-1 from Drosophila.   DOI:  10.1016/s0960-9822(03)00010-1 ;  PMID:  12573220
• Arabidopsis HEN1: a genetic link between endogenous miRNA controlling development and siRNA controlling transgene silencing and virus resistance.   DOI:  10.1016/s0960-9822(03)00293-8 ;  PMID:  12747833
• Negative feedback regulation of Dicer-Like1 in Arabidopsis by microRNA-guided mRNA degradation.   DOI:  10.1016/s0960-9822(03)00281-1 ;  PMID:  12725739
• Evidence for nuclear processing of plant micro RNA and short interfering RNA precursors.   DOI:  10.1104/pp.103.021980 ;  PMID:  12857820
• The nuclear dsRNA binding protein HYL1 is required for microRNA accumulation and plant development, but not posttranscriptional transgene silencing.   DOI:  10.1016/j.cub.2004.01.035 ;  PMID:  14972688
• Genetic and functional diversification of small RNA pathways in plants.   DOI:  10.1371/journal.pbio.0020104 ;  PMID:  15024409
• Arabidopsis micro-RNA biogenesis through Dicer-like 1 protein functions.   DOI:  10.1073/pnas.0403115101 ;  PMID:  15314213
• Endogenous trans-acting siRNAs regulate the accumulation of Arabidopsis mRNAs.   DOI:  10.1016/j.molcel.2004.09.028 ;  PMID:  15469823
• microRNA-directed phasing during trans-acting siRNA biogenesis in plants.   DOI:  10.1016/j.cell.2005.04.004 ;  PMID:  15851028
• Regulation of Arabidopsis shoot apical meristem and lateral organ formation by microRNA miR166g and its AtHD-ZIP target genes.   DOI:  10.1242/dev.01942 ;  PMID:  16033795
• Methylation protects miRNAs and siRNAs from a 3'-end uridylation activity in Arabidopsis.   DOI:  10.1016/j.cub.2005.07.029 ;  PMID:  16111943
• A plant RNA virus suppresses RNA silencing through viral RNA replication.   DOI:  10.1038/sj.emboj.7600776 ;  PMID:  16096641
• Partially redundant functions of Arabidopsis DICER-like enzymes and a role for DCL4 in producing trans-acting siRNAs.   DOI:  10.1016/j.cub.2005.07.024 ;  PMID:  16040244
• It's a small RNA world, after all.   DOI:  10.1126/science.1117805 ;  PMID:  16141062
• MicroRNA biogenesis and function in plants.   DOI:  10.1016/j.febslet.2005.07.071 ;  PMID:  16144699
• Specific interactions between Dicer-like proteins and HYL1/DRB-family dsRNA-binding proteins in Arabidopsis thaliana.   DOI:  10.1007/s11103-004-6853-5 ;  PMID:  15821876
• Ectopic DICER-LIKE1 expression in P1/HC-Pro Arabidopsis rescues phenotypic anomalies but not defects in microRNA and silencing pathways.   DOI:  10.1105/tpc.105.036608 ;  PMID:  16214897
• The interaction between DCL1 and HYL1 is important for efficient and precise processing of pri-miRNA in plant microRNA biogenesis.   DOI:  10.1261/rna.2146906 ;  PMID:  16428603
• Characterization of 43 non-protein-coding mRNA genes in Arabidopsis, including the MIR162a-derived transcripts.   DOI:  10.1104/pp.105.073817 ;  PMID:  16500993
• Dissecting Arabidopsis thaliana DICER function in small RNA processing, gene silencing and DNA methylation patterning.   DOI:  10.1038/ng1804 ;  PMID:  16699516
• DRB4-dependent TAS3 trans-acting siRNAs control leaf morphology through AGO7.   DOI:  10.1016/j.cub.2006.03.035 ;  PMID:  16682354
• An antagonistic function for Arabidopsis DCL2 in development and a new function for DCL4 in generating viral siRNAs.   DOI:  10.1038/sj.emboj.7601217 ;  PMID:  16810317
• SERRATE is a novel nuclear regulator in primary microRNA processing in Arabidopsis.   DOI:  10.1111/j.1365-313X.2006.02835.x ;  PMID:  16889646
• Four plant Dicers mediate viral small RNA biogenesis and DNA virus induced silencing.   DOI:  10.1093/nar/gkl886 ;  PMID:  17090584
• A diverse and evolutionarily fluid set of microRNAs in Arabidopsis thaliana.   DOI:  10.1101/gad.1476406 ;  PMID:  17182867
• RNA silencing of host transcripts by cauliflower mosaic virus requires coordinated action of the four Arabidopsis Dicer-like proteins.   DOI:  10.1073/pnas.0604627103 ;  PMID:  17164336
• The N-terminal double-stranded RNA binding domains of Arabidopsis HYPONASTIC LEAVES1 are sufficient for pre-microRNA processing.   DOI:  10.1105/tpc.106.048637 ;  PMID:  17337628
• Arabidopsis primary microRNA processing proteins HYL1 and DCL1 define a nuclear body distinct from the Cajal body.   DOI:  10.1073/pnas.0701061104 ;  PMID:  17369351
• Identification of nuclear dicing bodies containing proteins for microRNA biogenesis in living Arabidopsis plants.   DOI:  10.1016/j.cub.2007.04.005 ;  PMID:  17442570
• and intercellular RNA interference in Arabidopsis thaliana requires components of the microRNA and heterochromatic silencing pathways.   DOI:  10.1038/ng2081 ;  PMID:  17558406
• Location of a possible miRNA processing site in SmD3/SmB nuclear bodies in Arabidopsis.   DOI:  10.1093/pcp/pcm099 ;  PMID:  17675322
• A novel class of bacteria-induced small RNAs in Arabidopsis.   DOI:  10.1101/gad.1595107 ;  PMID:  18003861
• The disturbance of small RNA pathways enhanced abscisic acid response and multiple stress responses in Arabidopsis.   DOI:  10.1111/j.1365-3040.2008.01786.x ;  PMID:  18208512
• Dual roles of the nuclear cap-binding complex and SERRATE in pre-mRNA splicing and microRNA processing in Arabidopsis thaliana.   DOI:  10.1073/pnas.0802493105 ;  PMID:  18550839
• Global analysis of Arabidopsis gene expression uncovers a complex array of changes impacting pathogen response and cell cycle during geminivirus infection.   DOI:  10.1104/pp.108.121038 ;  PMID:  18650403
• The FHA domain proteins DAWDLE in Arabidopsis and SNIP1 in humans act in small RNA biogenesis.   DOI:  10.1073/pnas.0804218105 ;  PMID:  18632581
• The RNA-binding proteins HYL1 and SE promote accurate in vitro processing of pri-miRNA by DCL1.   DOI:  10.1073/pnas.0803356105 ;  PMID:  18632569
• The roles of plant dsRNA-binding proteins in RNAi-like pathways.   DOI:  10.1016/j.febslet.2008.07.004 ;  PMID:  18625233
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• Evolution of Arabidopsis MIR genes generates novel microRNA classes.   DOI:  10.1093/nar/gkn670 ;  PMID:  18842626
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• SINE RNA induces severe developmental defects in Arabidopsis thaliana and interacts with HYL1 (DRB1), a key member of the DCL1 complex.   DOI:  10.1371/journal.pgen.1000096 ;  PMID:  18551175
• A dominant mutation in DCL1 suppresses the hyl1 mutant phenotype by promoting the processing of miRNA.   DOI:  10.1261/rna.1297109 ;  PMID:  19155326
• Computational and analytical framework for small RNA profiling by high-throughput sequencing.   DOI:  10.1261/rna.1473809 ;  PMID:  19307293
• Histone acetyltransferase GCN5 interferes with the miRNA pathway in Arabidopsis.   DOI:  10.1038/cr.2009.59 ;  PMID:  19436261
• A loop-to-base processing mechanism underlies the biogenesis of plant microRNAs miR319 and miR159.   DOI:  10.1038/emboj.2009.292 ;  PMID:  19816405
• Structure of the Arabidopsis thaliana DCL4 DUF283 domain reveals a noncanonical double-stranded RNA-binding fold for protein-protein interaction.   DOI:  10.1261/rna.1965310 ;  PMID:  20106953
• RNAi-mediated down-regulation of DCL1 and AGO1 induces developmental changes in resynthesized Arabidopsis allotetraploids.   DOI:  10.1111/j.1469-8137.2010.03187.x ;  PMID:  20409179
• Structure of Arabidopsis HYPONASTIC LEAVES1 and its molecular implications for miRNA processing.   DOI:  10.1016/j.str.2010.02.006 ;  PMID:  20462493
• Argonaute quenching and global changes in Dicer homeostasis caused by a pathogen-encoded GW repeat protein.   DOI:  10.1101/gad.1908710 ;  PMID:  20439431
• siRNAs from miRNA sites mediate DNA methylation of target genes.   DOI:  10.1093/nar/gkq590 ;  PMID:  20621980
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• MicroRNAs prevent precocious gene expression and enable pattern formation during plant embryogenesis.   DOI:  10.1101/gad.1986710 ;  PMID:  21123653
• MicroRNAs regulate the timing of embryo maturation in Arabidopsis.   DOI:  10.1104/pp.110.171355 ;  PMID:  21330492
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• The helicase and RNaseIIIa domains of Arabidopsis Dicer-Like1 modulate catalytic parameters during microRNA biogenesis.   DOI:  10.1104/pp.112.193508 ;  PMID:  22474216
• Systematic identification of functional plant modules through the integration of complementary data sources.   DOI:  10.1104/pp.112.196725 ;  PMID:  22589469
• Regulation of miRNA abundance by RNA binding protein TOUGH in Arabidopsis.   DOI:  10.1073/pnas.1204915109 ;  PMID:  22802657
• DRB2, DRB3 and DRB5 function in a non-canonical microRNA pathway in Arabidopsis thaliana.   DOI:  10.4161/psb.21518 ;  PMID:  22902697
• Roles of dicer-like and argonaute proteins in TAS-derived small interfering RNA-triggered DNA methylation.   DOI:  10.1104/pp.112.200279 ;  PMID:  22846193
• Genome-wide identification of reverse complementary microRNA genes in plants.   DOI:  10.1371/journal.pone.0046991 ;  PMID:  23110057
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• Crystal structure of Arabidopsis thaliana Dawdle forkhead-associated domain reveals a conserved phospho-threonine recognition cleft for dicer-like 1 binding.   DOI:  10.1093/mp/sst007 ;  PMID:  23313986
• NOT2 proteins promote polymerase II-dependent transcription and interact with multiple MicroRNA biogenesis factors in Arabidopsis.   DOI:  10.1105/tpc.112.105882 ;  PMID:  23424246
• A role for the RNA-binding protein MOS2 in microRNA maturation in Arabidopsis.   DOI:  10.1038/cr.2013.23 ;  PMID:  23399598
• Protein-coding cis-natural antisense transcripts have high and broad expression in Arabidopsis.   DOI:  10.1104/pp.112.212100 ;  PMID:  23457227
• Second double-stranded RNA binding domain of dicer-like ribonuclease 1: structural and biochemical characterization.   DOI:  10.1021/bi301247r ;  PMID:  23194006
• Complementation of HYPONASTIC LEAVES1 by double-strand RNA-binding domains of DICER-LIKE1 in nuclear dicing bodies.   DOI:  10.1104/pp.113.219071 ;  PMID:  23886622
• Small RNA pathways and diversity in model legumes: lessons from genomics.   DOI:  10.3389/fpls.2013.00236 ;  PMID:  23847640
• RACK1 scaffold proteins influence miRNA abundance in Arabidopsis.   DOI:  10.1111/tpj.12308 ;  PMID:  23941160
• Bidirectional processing of pri-miRNAs with branched terminal loops by Arabidopsis Dicer-like1.   DOI:  10.1038/nsmb.2646 ;  PMID:  23934148
• Dissecting the interactions of SERRATE with RNA and DICER-LIKE 1 in Arabidopsis microRNA precursor processing.   DOI:  10.1093/nar/gkt667 ;  PMID:  23921632
• Construction of Specific Parallel Amplification of RNA Ends (SPARE) libraries for the systematic identification of plant microRNA processing intermediates.   DOI:  10.1016/j.ymeth.2013.08.032 ;  PMID:  24018204
• Fungal small RNAs suppress plant immunity by hijacking host RNA interference pathways.   DOI:  10.1126/science.1239705 ;  PMID:  24092744
• Identification of proteins enriched in rice egg or sperm cells by single-cell proteomics.   DOI:  10.1371/journal.pone.0069578 ;  PMID:  23936051
• The SERRATE protein is involved in alternative splicing in Arabidopsis thaliana.   DOI:  10.1093/nar/gkt894 ;  PMID:  24137006
• Transcription termination and chimeric RNA formation controlled by Arabidopsis thaliana FPA.   DOI:  10.1371/journal.pgen.1003867 ;  PMID:  24204292
• Salicylic acid and gentisic acid induce RNA silencing-related genes and plant resistance to RNA pathogens.   DOI:  10.1016/j.plaphy.2014.01.016 ;  PMID:  24531234
• miRNAs trigger widespread epigenetically activated siRNAs from transposons in Arabidopsis.   DOI:  10.1038/nature13069 ;  PMID:  24670663
• Arabidopsis miR156 Regulates Tolerance to Recurring Environmental Stress through SPL Transcription Factors.   DOI:  10.1105/tpc.114.123851 ;  PMID:  24769482
• Reprint of: construction of Specific Parallel Amplification of RNA Ends (SPARE) libraries for the systematic identification of plant microRNA processing intermediates.   DOI:  10.1016/j.ymeth.2014.04.001 ;  PMID:  24731939
• Long non-coding RNAs: a novel endogenous source for the generation of Dicer-like 1-dependent small RNAs in Arabidopsis thaliana.   DOI:  10.4161/rna.28725 ;  PMID:  24717238
• Global Regulation of Embryonic Patterning in Arabidopsis by MicroRNAs.   DOI:  10.1104/pp.114.240846 ;  PMID:  24784759
• A trihelix DNA binding protein counterbalances hypoxia-responsive transcriptional activation in Arabidopsis.   DOI:  10.1371/journal.pbio.1001950 ;  PMID:  25226037
• Structural determinants of Arabidopsis thaliana Hyponastic leaves 1 function in vivo.   DOI:  10.1371/journal.pone.0113243 ;  PMID:  25409478
• The rolB gene activates the expression of genes encoding microRNA processing machinery.   DOI:  10.1007/s10529-014-1743-7 ;  PMID:  25491479
• PRL1, an RNA-binding protein, positively regulates the accumulation of miRNAs and siRNAs in Arabidopsis.   DOI:  10.1371/journal.pgen.1004841 ;  PMID:  25474114
• Diversity, expression and mRNA targeting abilities of Argonaute-targeting miRNAs among selected vascular plants.   DOI:  10.1186/1471-2164-15-1049 ;  PMID:  25443390
• DICER-LIKE1 processed trans-acting siRNAs mediate DNA methylation: case study of complex small RNA biogenesis and action pathways in plants.   DOI:  10.4161/psb.22476 ;  PMID:  23104109
• CMA33/XCT Regulates Small RNA Production through Modulating the Transcription of Dicer-Like Genes in Arabidopsis.   DOI:  10.1016/j.molp.2015.03.002 ;  PMID:  25770820
• Phytophthora effector targets a novel component of small RNA pathway in plants to promote infection.   DOI:  10.1073/pnas.1421475112 ;  PMID:  25902521
• Induced folding in RNA recognition by Arabidopsis thaliana DCL1.   DOI:  10.1093/nar/gkv627 ;  PMID:  26101256
• Retraction for Moissiard and Voinnet, RNA silencing of host transcripts by cauliflower mosaic virus requires coordinated action of the four Arabidopsis Dicer-like proteins.   DOI:  10.1073/pnas.1513620112 ;  PMID:  26216957
• Endogenous Arabidopsis messenger RNAs transported to distant tissues.   DOI:  10.1038/nplants.2015.25 ;  PMID:  27247031
• KH domain protein RCF3 is a tissue-biased regulator of the plant miRNA biogenesis cofactor HYL1.   DOI:  10.1073/pnas.1512865112 ;  PMID:  26512101
• The Roles of Arabidopsis CDF2 in Transcriptional and Posttranscriptional Regulation of Primary MicroRNAs.   DOI:  10.1371/journal.pgen.1005598 ;  PMID:  26473486
• Expression of Concern: Misregulation of AUXIN RESPONSE FACTOR 8 Underlies the Developmental Abnormalities Caused by Three Distinct Viral Silencing Suppressors in Arabidopsis.   DOI:  10.1371/journal.ppat.1005234 ;  PMID:  26451730
• Dicer-independent RNA-directed DNA methylation in Arabidopsis.   DOI:  10.1038/cr.2015.145 ;  PMID:  26642813
• Chimeric DCL1-Partnering Proteins Provide Insights into the MicroRNA Pathway.   DOI:  10.3389/fpls.2015.01201 ;  PMID:  26779232
• dsRNA-protein interactions studied by molecular dynamics techniques. Unravelling dsRNA recognition by DCL1.   DOI:  10.1016/j.abb.2016.03.013 ;  PMID:  26987516
• Correction: Misregulation of AUXIN RESPONSE FACTOR 8 Underlies the Developmental Abnormalities Caused by Three Distinct Viral Silencing Suppressors in Arabidopsis.   DOI:  10.1371/journal.ppat.1005627 ;  PMID:  27148883
• Transcription and processing of primary microRNAs are coupled by Elongator complex in Arabidopsis.   DOI:  10.1038/nplants.2015.75 ;  PMID:  27250010
• Metabolomic analysis reveals the relationship between AZI1 and sugar signaling in systemic acquired resistance of Arabidopsis.   DOI:  10.1016/j.plaphy.2016.06.016 ;  PMID:  27337039
• Analyses of RNA-Seq and sRNA-Seq data reveal a complex network of anti-viral defense in TCV-infected Arabidopsis thaliana.   DOI:  10.1038/srep36007 ;  PMID:  27782158
• Recovery of dicer-like 1-late flowering phenotype by miR172 expressed by the noncanonical DCL4-dependent biogenesis pathway.   DOI:  10.1261/rna.044966.114 ;  PMID:  24966167
• Homodimerization of HYL1 ensures the correct selection of cleavage sites in primary miRNA.   DOI:  10.1093/nar/gku907 ;  PMID:  25294831
• In vitro Reconstitution Assay of miRNA Biogenesis by Arabidopsis DCL1.   DOI:  10.21769/bioprotoc.1454 ;  PMID:  27430007
• Pre-microRNA processing activity in nuclear extracts from Arabidopsis suspension cells.   DOI:  10.1007/s10265-016-0874-4 ;  PMID:  27885505
• Intron Lariat RNA Inhibits MicroRNA Biogenesis by Sequestering the Dicing Complex in Arabidopsis.   DOI:  10.1371/journal.pgen.1006422 ;  PMID:  27870853
• Both AtrbohD and AtrbohF are essential for mediating responses to oxygen deficiency in Arabidopsis.   DOI:  10.1007/s00299-017-2128-x ;  PMID:  28337518
• HIGLE is a bifunctional homing endonuclease that directly interacts with HYL1 and SERRATE in Arabidopsis thaliana.   DOI:  10.1002/1873-3468.12628 ;  PMID:  28321834
• Disruption of morphogenesis and transformation of the suspensor in abnormal suspensor mutants of Arabidopsis.   DOI:  10.1242/dev.120.11.3235 ;  PMID:  28534607
• Loss of function of Arabidopsis microRNA-machinery genes impairs fertility, and has effects on homologous recombination and meiotic chromatin dynamics.   DOI:  10.1038/s41598-017-07702-x ;  PMID:  28839139
• Arabidopsis thaliana miRNAs promote embryo pattern formation beginning in the zygote.   DOI:  10.1016/j.ydbio.2017.09.009 ;  PMID:  28912016
• [A Betasatellite-Encoded Protein Regulates Key Components of Gene Silencing System in Plants].   DOI:  10.7868/S002689841703003X ;  PMID:  28900084
• The siRNA suppressor RTL1 is redox-regulated through glutathionylation of a conserved cysteine in the double-stranded-RNA-binding domain.   DOI:  10.1093/nar/gkx820 ;  PMID:  28981840
• MAC3A and MAC3B, Two Core Subunits of the MOS4-Associated Complex, Positively Influence miRNA Biogenesis.   DOI:  10.1105/tpc.17.00953 ;  PMID:  29437988
• Coordinated regulation of Arabidopsis microRNA biogenesis and red light signaling through Dicer-like 1 and phytochrome-interacting factor 4.   DOI:  10.1371/journal.pgen.1007247 ;  PMID:  29522510
• Conformational sampling of the intrinsically disordered dsRBD-1 domain from Arabidopsis thaliana DCL1.   DOI:  10.1039/c7cp07908g ;  PMID:  29632904
• SWI2/SNF2 ATPase CHR2 remodels pri-miRNAs via Serrate to impede miRNA production.   DOI:  10.1038/s41586-018-0135-x ;  PMID:  29769717
• DAWDLE Interacts with DICER-LIKE Proteins to Mediate Small RNA Biogenesis.   DOI:  10.1104/pp.18.00354 ;  PMID:  29784765
• Regulation of Plant Microprocessor Function in Shaping microRNA Landscape.   DOI:  10.3389/fpls.2018.00753 ;  PMID:  29922322
• SMA1, a homolog of the splicing factor Prp28, has a multifaceted role in miRNA biogenesis in Arabidopsis.   DOI:  10.1093/nar/gky591 ;  PMID:  29982637
• Gene regulation by translational inhibition is determined by Dicer partnering proteins.   DOI:  10.1038/nplants.2014.27 ;  PMID:  27246880
• Transcriptional read-through of the long non-coding RNA SVALKA governs plant cold acclimation.   DOI:  10.1038/s41467-018-07010-6 ;  PMID:  30385760
• Detection of MicroRNA Processing Intermediates Through RNA Ligation Approaches.   DOI:  10.1007/978-1-4939-9042-9_20 ;  PMID:  30701507
• Alternative use of miRNA-biogenesis co-factors in plants at low temperatures.   DOI:  10.1242/dev.172932 ;  PMID:  30760482
• Genome-wide identification of EMBRYO-DEFECTIVE (EMB) genes required for growth and development in Arabidopsis.   DOI:  10.1111/nph.16071 ;  PMID:  31334862
• Light Triggers the miRNA-Biogenetic Inconsistency for De-etiolated Seedling Survivability in Arabidopsis thaliana.   DOI:  10.1016/j.molp.2019.10.011 ;  PMID:  31678531
• Translational Landscape of Protein-Coding and Non-Protein-Coding RNAs upon Light Exposure in Arabidopsis.   DOI:  10.1093/pcp/pcz219 ;  PMID:  31794029
• Dual function of HYPONASTIC LEAVES 1 during early skotomorphogenic growth in Arabidopsis.   DOI:  10.1111/tpj.14681 ;  PMID:  31922639
• Phylogenetic analyses of key developmental genes provide insight into the complex evolution of seeds.   DOI:  10.1016/j.ympev.2020.106778 ;  PMID:  32165160
• HUA ENHANCER1 Mediates Ovule Development.   DOI:  10.3389/fpls.2020.00397 ;  PMID:  32351522
• The Intrinsically Disordered Protein CARP9 Bridges HYL1 to AGO1 in the Nucleus to Promote MicroRNA Activity.   DOI:  10.1104/pp.20.00258 ;  PMID:  32636339
• mRNA adenosine methylase (MTA) deposits m(6)A on pri-miRNAs to modulate miRNA biogenesis in Arabidopsis thaliana.   DOI:  10.1073/pnas.2003733117 ;  PMID:  32817553
• AGL15 Controls the Embryogenic Reprogramming of Somatic Cells in Arabidopsis through the Histone Acetylation-Mediated Repression of the miRNA Biogenesis Genes.   DOI:  10.3390/ijms21186733 ;  PMID:  32937992
• Phase separation of SERRATE drives dicing body assembly and promotes miRNA processing in Arabidopsis.   DOI:  10.1038/s41556-020-00606-5 ;  PMID:  33288888
• HASTY modulates miRNA biogenesis by linking pri-miRNA transcription and processing.   DOI:  10.1016/j.molp.2020.12.019 ;  PMID:  33385584
• MicroRNA775 regulates intrinsic leaf size and reduces cell wall pectin levels by targeting a galactosyltransferase gene in Arabidopsis.   DOI:  10.1093/plcell/koaa049 ;  PMID:  33955485
• Direct Molecular Evidence for an Ancient, Conserved Developmental Toolkit Controlling Posttranscriptional Gene Regulation in Land Plants.   DOI:  10.1093/molbev/msab201 ;  PMID:  34196710
• Structural basis of microRNA processing by Dicer-like 1.   DOI:  10.1038/s41477-021-01000-1 ;  PMID:  34593993
• Unpaired nucleotides on the stem of microRNA precursor are important for precise cleavage by Dicer-like 1 in Arabidopsis.   DOI:  10.1111/gtc.12927 ;  PMID:  35143697
• Safeguard DCL2-Dependent 22-nt siRNA generation by DCL1.   DOI:  10.1016/j.bbrc.2022.03.076 ;  PMID:  35316769
• Sucrose synthase activity is not required for cellulose biosynthesis in Arabidopsis.   DOI:  10.1111/tpj.15752 ;  PMID:  35362151
• Chromatin-associated microprocessor assembly is regulated by the U1 snRNP auxiliary protein PRP40.   DOI:  10.1093/plcell/koac278 ;  PMID:  36087009
• microRNA production in Arabidopsis.   DOI:  10.3389/fpls.2023.1096772 ;  PMID:  36743500
• Hyponastic Leaves 1 Interacts with RNA Pol II to Ensure Proper Transcription of MicroRNA Genes.   DOI:  10.1093/pcp/pcad032 ;  PMID:  37040378
• Solution structure and behaviour of the Arabidopsis thaliana HYL1 protein.   DOI:  10.1016/j.bbagen.2023.130376 ;  PMID:  37150226

Sequences: