Gene Details:

  • Gene ID: Gbar_D04G005070
  • Gene Symbol: GbCML45
  • Gene Name: calmodulin-like 45
  • Genome:
  • Species: Gossypium barbadense

Functional Descriptions:

  • Positive roles of the Ca2+ sensors GbCML45 and GbCML50 in improving cotton Verticillium wilt resistance.
  • Discovered that the expression level of GbCML45 was promoted after V. dahliae infection in roots of cotton, suggesting its potential role in Verticillium wilt resistance.
  • Knockdown of GbCML45 in cotton plants decreased resistance while overexpression of GbCML45 in Arabidopsis thaliana plants enhanced resistance to V. dahliae infection.
  • Detailed investigations indicated that several defence-related pathways, including salicylic acid, ethylene, reactive oxygen species and nitric oxide signalling pathways, as well as accumulations of lignin and callose, are responsible for GbCML45- and GbCML50-modulated V. dahliae resistance in cotton.
  • Both GbCML45 and GbCML50 positively regulate Verticillium wilt resistance in Arabidopsis as their Arabidopsis homologues AtCML46 and AtCML49.
  • These results collectively indicated that GbCML45 and GbCML50 act as positive regulators to improve cotton Verticillium wilt resistance, providing potential targets for exploitation of improved Verticillium wilt-tolerant cotton cultivars by genetic engineering and molecular breeding.

Literature:

Gene Resources:

  • NCBI ID:
  • UniProt accessions:

Orthologs:

Sequences:

  • CDS Sequence:
  • Protein Sequence: