Gene Details:

• Gene ID: Seita.4G058800
• Gene Symbol: SiSTL1
• Gene Name:
• Genome:
• Species: Setaria italica

Functional Descriptions:

• SiSTL1, encoding a large subunit of ribonucleotide reductase, is crucial for plant growth, chloroplast biogenesis, and cell cycle progression in Setaria italica.
• Identified a RNR large subunit mutant, SiSTL1, in Setaria italica (foxtail millet), which exhibited growth retardation as well as striped leaf phenotype, i.e. irregularly reduced leaf vein distances and decreased chloroplast biogenesis.
• Determined that a Gly737 to Glu substitution occurring in the C-terminus of the SiSTL1 protein slightly affected its optimal function, leading in turn to the reduced expression of genes variously involved in the assembly and activation of the DNA pre-replicative complex, elongation of replication forks and S phase entry.
• Our study provides new insights into how SiSTL1 regulates plant growth, chloroplast biogenesis, and cell cycle progression in Poaceae crops.

Function-related keywords:

• leaf ,  chloroplast ,  growth ,  plant-growth ,  cell-elongation ,  cell-cycle ,  chloroplast-biogenesis ,  protein

Literature:

• SiSTL1, encoding a large subunit of ribonucleotide reductase, is crucial for plant growth, chloroplast biogenesis, and cell cycle progression in Setaria italica.   DOI:  10.1093/jxb/ery429 ;  PMID:  30534992

Related News:

Gene Resources:

• NCBI ID:
• UniProt accessions:

Orthologs:

Sequences:

• CDS Sequence:
• Protein Sequence: