Gene Details:

Functional Descriptions:

  • The SmMYB36-SmERF6/SmERF115 module regulates the biosynthesis of tanshinones and phenolic acids in salvia miltiorrhiza hairy roots.
  • SmERF6, a positive regulator of tanshinone synthesis activating SmCPS1, was up-regulated and SmERF115, a positive regulator of phenolic acid biosynthesis activating SmRAS, was down-regulated.
  • SmERF6 directly co-regulates tanshinone biosynthesis by binding to the ethylene response element (GCC-box) of SmKSL1 and SmCPS1 promoters and activating their transcription to promote tanshinone biosynthesis.
  • The ethylene response factor SmERF6 co-regulates the transcription of SmCPS1 and SmKSL1 and is involved in tanshinone biosynthesis in Salvia miltiorrhiza hairy roots.
  • SmERF6 shifted available resources to enhance tanshinone accumulation.

Literature:

Gene Resources:

Orthologs:

Sequences:

  • CDS Sequence:
  • Protein Sequence: