Gene Details:
- Gene ID: SmiContig1859
- Gene Symbol: SmMYB2
- Gene Name:
- Genome: S. miltiorrhiza genome
- Species: Salvia miltiorrhiza
Functional Descriptions:
- SmMYB2 promotes salvianolic acid biosynthesis in the medicinal herb Salvia miltiorrhiza.
- Identified the MeJA-responsive R2R3-MYB transcription factor gene SmMYB2 from a transcriptome library produced from MeJA-treated S. miltiorrhiza hairy roots.
- SmMYB2 expression was tightly correlated with the expression of key salvianolic acid biosynthetic genes including CYP98A14. SmMYB2 was highly expressed in the periderm of S. miltiorrhiza and SmMYB2 localized to the nucleus.
- Overexpressing SmMYB2 in S. miltiorrhiza hairy roots significantly increased the levels of salvianolic acids (including rosmarinic acid and salvianolic acid B) by upregulating salvianolic acid biosynthetic genes such as CYP98A14.
- These findings reveal the novel regulatory role of SmMYB2 in MeJA-mediated phenolic acid biosynthesis, providing a useful target gene for metabolic engineering and shedding light on the salvianolic acid regulatory network.
Function-related keywords:
Literature:
- SmMYB2 promotes salvianolic acid biosynthesis in the medicinal herb Salvia miltiorrhiza. DOI: 10.1111/jipb.12943 ; PMID: 32343491
Related News:
Gene Resources:
Orthologs:
Sequences:
- CDS Sequence:
- Protein Sequence: