Gene Details:

• Gene ID: GWHPAAYT014255
• Gene Symbol: PbbZIP4
• Gene Name:
• Genome:
• Species: Pyrus betulifolia

Functional Descriptions:

• Transcription factor PbbZIP4 is targeted for proteasome-mediated degradation by the ubiquitin ligase PbATL18 to influence pear’s resistance to Colletotrichum fructicola by regulating the expression of PbNPR3.
• Found that an E3 ubiquitin ligase, PbATL18, interacts with and ubiquitinates the transcription factor PbbZIP4, and this process is enhanced by C. fructicola infection.
• Silencing PbATL18 and PbbZIP4 in Pyrus betulaefolia seedlings resulted in opposite effects, with PbbZIP4 silencing enhancing resistance to C. fructicola infection and PbATL18 silencing increasing sensitivity to C. fructicola infection.
• PbbZIP4 was ubiquitinated by PbATL18 and degraded by the 26S proteasome, which decreased the expression of PbNPR3 and promoted SA signal transduction, thereby enhancing plant C. fructicola resistance.

Function-related keywords:

• transcription-factor ,  seedlings ,  resistance ,  signal-transduction ,  ubiquitin ,  sa ,  ubiquitin-e3-ligase

Literature:

• Transcription factor PbbZIP4 is targeted for proteasome-mediated degradation by the ubiquitin ligase PbATL18 to influence pear's resistance to Colletotrichum fructicola by regulating the expression of PbNPR3.   DOI:  10.1111/tpj.16417 ;  PMID:  37549222

Related News:

Gene Resources:

• NCBI ID:
• UniProt accessions:

Orthologs:

Sequences:

• CDS Sequence:
• Protein Sequence: