Gene Details:
Functional Descriptions:
- PgLOX6 encoding a lipoxygenase contributes to jasmonic acid biosynthesis and ginsenoside production in Panax ginseng.
- The expression of PgLOX6 was high in vascular bundles, which corresponds with expression of ginsenoside biosynthetic genes.
- Consistent with the role of PgLOX6 in synthesizing JA and promoting ginsenoside synthesis, transgenic plants overexpressing PgLOX6 in Arabidopsis had increased amounts of JA and methyl jasmonate (MJ), increased expression of triterpene biosynthetic genes such as squalene synthase (AtSS1) and squalene epoxidase (AtSE1), and increased squalene content.
- These results demonstrate that PgLOX6 is responsible for the biosynthesis of JA and promotion of the production of triterpenoid saponin through up-regulating the expression of ginsenoside biosynthetic genes. This work provides insight into the role of JA in biosynthesizing secondary metabolites and provides a molecular tool for increasing ginsenoside production.
Function-related keywords:
Literature:
- PgLOX6 encoding a lipoxygenase contributes to jasmonic acid biosynthesis and ginsenoside production in Panax ginseng. DOI: 10.1093/jxb/erw413 ; PMID: 27831475
Related News:
Gene Resources:
- NCBI ID: MG807656.1
- UniProt accessions:
Orthologs:
Sequences:
- CDS Sequence:
- Protein Sequence: