Gene Details:
- Gene ID:
- Gene Symbol: RhoGDI2
- Gene Name: Guanine Nucleotide Dissociation Inhibitor2
- Genome:
- Species: Nicotiana tabacum
Functional Descriptions:
- Bimolecular fluorescence complementation analysis shows in vivo interaction between wild type Nt-Rac5 and Nt-RhoGDI2 fusion proteins.
- The results of this study strongly support the model of Nt-RhoGAP1 and Nt-RhoGDI2 functions in the apical polarization of Nt-Rac5 activity described above, and enhance our understanding of apical dynamics of Rac/Rop signaling proteins.
- This observation demonstrates that Nt-RhoGDI2 can interact with membrane-associated Nt-Rac5, as required for the proposed recycling mechanism.
- Confirmation of this model by the analysis of in situ interactions between Nt-Rac5 variants and Nt-RhoGAP1 or Nt-RhoGDI2 in living pollen tubes has been missing.
Function-related keywords:
Literature:
- In vivo Rac/Rop localization as well as interaction with RhoGAP and RhoGDI in tobacco pollen tubes: analysis by low-level expression of fluorescent fusion proteins and bimolecular fluorescence complementation. DOI: 10.1111/tpj.12961 ; PMID: 26252733
Related News:
Gene Resources:
- NCBI ID: DQ416769.1
- UniProt accessions:
Orthologs:
Sequences:
- CDS Sequence:
- Protein Sequence: