Gene Details:
Functional Descriptions:
- Nt-RhoGDI2 regulates Rac/Rop signaling and polar cell growth in tobacco pollen tubes.
- Nt-RhoGDI2, a homolog of guanine nucleotide dissociation inhibitors (GDIs) regulating Rho signaling in animals and yeast, is co-expressed with the Rac/Rop GTPase Nt-Rac5 specifically in tobacco (Nicotiana tabacum) pollen tubes.
- Transient over-expression of Nt-Rac5 and Nt-RhoGDI2 depolarized or inhibited tobacco pollen tube growth, respectively.
- Nt-RhoGDI2 was localized to the pollen tube cytoplasm and effectively transferred co-over-expressed YFP–Nt-Rac5 fusion proteins from the plasma membrane to this compartment.
- Based on these observations, we propose that Nt-RhoGDI2-mediated recycling of Nt-Rac5 from the flanks of the tip to the apex has an essential function in the maintenance of polarized Rac/Rop signaling and cell expansion in pollen tubes.
Function-related keywords:
Literature:
- Nt-RhoGDI2 regulates Rac/Rop signaling and polar cell growth in tobacco pollen tubes. DOI: 10.1111/j.1365-313X.2006.02757.x ; PMID: 16805734
Related News:
Gene Resources:
- NCBI ID: DQ416769.1
- UniProt accessions: Q1ZZN8
Orthologs:
Sequences:
- CDS Sequence:
- Protein Sequence: